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Prognostic significance of Dickkopf-1 in head and neck squamous cell carcinoma
CONCLUSION: DKK1 holds promise as a potential biomarker for predicting poor prognosis in HNSC patients, but further research is needed for confirmation.PMID:38044867 | DOI:10.1080/14737140.2023.2289597 (Source: Expert Review of Anticancer Therapy)
Source: Expert Review of Anticancer Therapy - December 4, 2023 Category: Cancer & Oncology Authors: Kai Chen Jin Li Yanfeng Ouyang Yulong Xie Guiqiong Xu Tianliang Xia Rui You Guichao Liu Han He Rong Huang Mingyuan Chen Source Type: research

Ifosfamide-induced nephrotoxicity in oncological patients
Expert Rev Anticancer Ther. 2023 Nov 30:1-10. doi: 10.1080/14737140.2023.2290196. Online ahead of print.ABSTRACTINTRODUCTION: Ifosfamide is an alkylating chemotherapeutic agent used in the treatment of various neoplasms. Its main adverse effects include renal damage.AREAS COVERED: A comprehensive review was conducted, including 100 articles from the Scielo, Scopus, and EMBASE databases. Ifosfamide-induced nephrotoxicity is attributed to its toxic metabolites, such as acrolein and chloroacetaldehyde, which cause mitochondrial damage and oxidative stress in renal tubular cells. Literature review found a 29-year average age w...
Source: Expert Review of Anticancer Therapy - November 30, 2023 Category: Cancer & Oncology Authors: Juan Eduardo Quiroz-Aldave Mar ía Del Carmen Durand-Vásquez Freddy Shanner Ch ávez-Vásquez Alexandra Noelia Rodr íguez-Angulo Sonia Elizabeth Gonz áles-Saldaña Carlos C ésar Alcalde-Loyola Julia Cristina Coronado-Arroyo Francisca Elena Zavaleta-Gu Source Type: research