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New drugs targeting calcitonin gene-related peptide for the management of migraines
Expert Opin Emerg Drugs. 2023 Nov 23. doi: 10.1080/14728214.2023.2288334. Online ahead of print.ABSTRACTINTRODUCTION: Significant advances in migraine research have contributed to the development of new drugs for the treatment of migraine. Monoclonal antibodies (mAbs) against Calcitonin Gene-Related Peptide (CGRP) or its receptor and CGRP receptor antagonists (gepants) have been associated with a good safety profile and resulted in an overall efficacy in reducing the number of monthly migraine days both in episodic and chronic forms of migraine.AREAS COVERED: The results from main investigation studies (phase 2 or 3) of CG...
Source: Expert Opinion on Emerging Drugs - November 23, 2023 Category: Drugs & Pharmacology Authors: Claudio Tana Francesco Cipollone Maria Adele Giamberardino Paolo Martelletti Source Type: research