Expression of Tim-3/galectin-9 pathway and CD8+T cells and related factors in patients with cystic echinococcosis
CONCLUSION: This study suggests that the high expression of Tim-3 on CD8+T cell surfaces in AE patients might promote an increase in CD8+CD28-T cells and related factors, while suppressing CTL and related factor expressions. This potentially induces the onset of immune tolerance, which is unfavorable for the clearance of Echinococcus multilocularis in patients, leading to the exacerbation of persistent infections.PMID:37793539 | DOI:10.1016/j.exppara.2023.108623 (Source: Experimental Parasitology)
Source: Experimental Parasitology - October 4, 2023 Category: Parasitology Authors: Hui Zhao Yuyu Ma Fengming Tian Bin Li Ning Xiao Xiaojin Mo Madinaimu Aibibula Hongyue Min Xuanlin Cai Ting Zhang Xiumin Ma Source Type: research
In vitro and in vivo studies on a group of chalcones find promising results as potential drugs against fascioliasis
Exp Parasitol. 2023 Sep 28:108628. doi: 10.1016/j.exppara.2023.108628. Online ahead of print.ABSTRACTAbout a third of the world population is infected by helminth parasites implicated in foodborne trematodiasis. Fascioliasis is a worldwide disease caused by trematodes of the genus Fasciola spp. It generates huge economic losses to the agri-food industry and is currently considered an emerging zoonosis by the World Health Organization (WHO). The only available treatment relies on anthelmintic drugs, being triclabendazole (TCBZ) the drug of choice to control human infections. The emergence of TCBZ resistance in several count...
Source: Experimental Parasitology - September 30, 2023 Category: Parasitology Authors: Zoraima Art ía Florencia Ferraro Carina S ánchez Hugo Cerecetto Jorge Gil Luc ía Pareja Mar ía Noel Alonzo Teresa Freire Mauricio Cabrera Ileana Corvo Source Type: research
In vitro and in vivo studies on a group of chalcones find promising results as potential drugs against fascioliasis
Exp Parasitol. 2023 Sep 28:108628. doi: 10.1016/j.exppara.2023.108628. Online ahead of print.ABSTRACTAbout a third of the world population is infected by helminth parasites implicated in foodborne trematodiasis. Fascioliasis is a worldwide disease caused by trematodes of the genus Fasciola spp. It generates huge economic losses to the agri-food industry and is currently considered an emerging zoonosis by the World Health Organization (WHO). The only available treatment relies on anthelmintic drugs, being triclabendazole (TCBZ) the drug of choice to control human infections. The emergence of TCBZ resistance in several count...
Source: Experimental Parasitology - September 30, 2023 Category: Parasitology Authors: Zoraima Art ía Florencia Ferraro Carina S ánchez Hugo Cerecetto Jorge Gil Luc ía Pareja Mar ía Noel Alonzo Teresa Freire Mauricio Cabrera Ileana Corvo Source Type: research
In vitro and in vivo studies on a group of chalcones find promising results as potential drugs against fascioliasis
Exp Parasitol. 2023 Sep 28:108628. doi: 10.1016/j.exppara.2023.108628. Online ahead of print.ABSTRACTAbout a third of the world population is infected by helminth parasites implicated in foodborne trematodiasis. Fascioliasis is a worldwide disease caused by trematodes of the genus Fasciola spp. It generates huge economic losses to the agri-food industry and is currently considered an emerging zoonosis by the World Health Organization (WHO). The only available treatment relies on anthelmintic drugs, being triclabendazole (TCBZ) the drug of choice to control human infections. The emergence of TCBZ resistance in several count...
Source: Experimental Parasitology - September 30, 2023 Category: Parasitology Authors: Zoraima Art ía Florencia Ferraro Carina S ánchez Hugo Cerecetto Jorge Gil Luc ía Pareja Mar ía Noel Alonzo Teresa Freire Mauricio Cabrera Ileana Corvo Source Type: research
Prevalence and effects of a parasitic trematode on the blue mussel, Mytilus edulis, in the Boston Harbor
Exp Parasitol. 2023 Sep 26:108624. doi: 10.1016/j.exppara.2023.108624. Online ahead of print.ABSTRACTThe blue mussel, Mytilus edulis, is a keystone species in the North Atlantic that plays critical roles in nutrient cycling, water filtration, and habitat creation. Blue mussel populations have declined significantly throughout the North Atlantic due to various factors, including habitat loss, pollution, increasing water temperature, and parasites. One parasite is Proctoeces maculatus, a digenetic trematode, which uses M. edulis as an intermediate host. This parasite causes reduced growth, castration, and death in mussels. T...
Source: Experimental Parasitology - September 28, 2023 Category: Parasitology Authors: K Garrett Evensen Alexandra E Figueroa Alyssa M Goncalves Tiffany J Chan Emily B Vu Isaac Hounain Helen C Poynton Source Type: research
Molecular identification and phylogenetic analysis of gastrointestinal nematodes in different populations of Kazakh sheep
This study provides valuable molecular approaches for epidemiological surveillance and for assisting in the control of Nematodirus infection in sheep.PMID:37769836 | DOI:10.1016/j.exppara.2023.108625 (Source: Experimental Parasitology)
Source: Experimental Parasitology - September 28, 2023 Category: Parasitology Authors: Xiaofei Yan Sangang He Yiyong Liu Bing Han Ning Zhang Haifeng Deng Yuqi Wang Mingjun Liu Source Type: research
Prevalence and effects of a parasitic trematode on the blue mussel, Mytilus edulis, in the Boston Harbor
Exp Parasitol. 2023 Sep 26:108624. doi: 10.1016/j.exppara.2023.108624. Online ahead of print.ABSTRACTThe blue mussel, Mytilus edulis, is a keystone species in the North Atlantic that plays critical roles in nutrient cycling, water filtration, and habitat creation. Blue mussel populations have declined significantly throughout the North Atlantic due to various factors, including habitat loss, pollution, increasing water temperature, and parasites. One parasite is Proctoeces maculatus, a digenetic trematode, which uses M. edulis as an intermediate host. This parasite causes reduced growth, castration, and death in mussels. T...
Source: Experimental Parasitology - September 28, 2023 Category: Parasitology Authors: K Garrett Evensen Alexandra E Figueroa Alyssa M Goncalves Tiffany J Chan Emily B Vu Isaac Hounain Helen C Poynton Source Type: research
Molecular identification and phylogenetic analysis of gastrointestinal nematodes in different populations of Kazakh sheep
This study provides valuable molecular approaches for epidemiological surveillance and for assisting in the control of Nematodirus infection in sheep.PMID:37769836 | DOI:10.1016/j.exppara.2023.108625 (Source: Experimental Parasitology)
Source: Experimental Parasitology - September 28, 2023 Category: Parasitology Authors: Xiaofei Yan Sangang He Yiyong Liu Bing Han Ning Zhang Haifeng Deng Yuqi Wang Mingjun Liu Source Type: research
Prevalence and effects of a parasitic trematode on the blue mussel, Mytilus edulis, in the Boston Harbor
Exp Parasitol. 2023 Sep 26:108624. doi: 10.1016/j.exppara.2023.108624. Online ahead of print.ABSTRACTThe blue mussel, Mytilus edulis, is a keystone species in the North Atlantic that plays critical roles in nutrient cycling, water filtration, and habitat creation. Blue mussel populations have declined significantly throughout the North Atlantic due to various factors, including habitat loss, pollution, increasing water temperature, and parasites. One parasite is Proctoeces maculatus, a digenetic trematode, which uses M. edulis as an intermediate host. This parasite causes reduced growth, castration, and death in mussels. T...
Source: Experimental Parasitology - September 28, 2023 Category: Parasitology Authors: K Garrett Evensen Alexandra E Figueroa Alyssa M Goncalves Tiffany J Chan Emily B Vu Isaac Hounain Helen C Poynton Source Type: research
Molecular identification and phylogenetic analysis of gastrointestinal nematodes in different populations of Kazakh sheep
This study provides valuable molecular approaches for epidemiological surveillance and for assisting in the control of Nematodirus infection in sheep.PMID:37769836 | DOI:10.1016/j.exppara.2023.108625 (Source: Experimental Parasitology)
Source: Experimental Parasitology - September 28, 2023 Category: Parasitology Authors: Xiaofei Yan Sangang He Yiyong Liu Bing Han Ning Zhang Haifeng Deng Yuqi Wang Mingjun Liu Source Type: research
Growth inhibitory effect of selected quinones from Indian medicinal plants against Theileria annulata
Exp Parasitol. 2023 Sep 25:108622. doi: 10.1016/j.exppara.2023.108622. Online ahead of print.ABSTRACTTropical Bovine Theileriosis, caused by the protozoan parasite Theileria annulata, poses a significant threat to cattle populations. Currently, Buparvaquone is the sole effective naphthoquinone drug commercially available for its treatment. In our research, we delved into the potential of naturally occurring quinones as alternative treatments. We isolated two quinones, emodin and chrysophanol, from Rheum emodi Wall, and two more, embelin and lawsone, from Embelia ribes Burm.f. and Lawsonia inermis L. respectively. We assess...
Source: Experimental Parasitology - September 27, 2023 Category: Parasitology Authors: Rose Mary Kiriyanthan A Radha Perumal Pandikumar Palavesam Azhahianambi N Madan Savarimuthu Ignacimuthu Source Type: research
Growth inhibitory effect of selected quinones from Indian medicinal plants against Theileria annulata
Exp Parasitol. 2023 Sep 25:108622. doi: 10.1016/j.exppara.2023.108622. Online ahead of print.ABSTRACTTropical Bovine Theileriosis, caused by the protozoan parasite Theileria annulata, poses a significant threat to cattle populations. Currently, Buparvaquone is the sole effective naphthoquinone drug commercially available for its treatment. In our research, we delved into the potential of naturally occurring quinones as alternative treatments. We isolated two quinones, emodin and chrysophanol, from Rheum emodi Wall, and two more, embelin and lawsone, from Embelia ribes Burm.f. and Lawsonia inermis L. respectively. We assess...
Source: Experimental Parasitology - September 27, 2023 Category: Parasitology Authors: Rose Mary Kiriyanthan A Radha Perumal Pandikumar Palavesam Azhahianambi N Madan Savarimuthu Ignacimuthu Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
