Experimental and Toxicologic Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research

Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells
Exp Toxicol Pathol. 2017 Oct 2;69(8):700-712. doi: 10.1016/j.etp.2017.08.001. Epub 2017 Sep 7.ABSTRACTEsculetin is a polyphenolic compound with cytoprotective properties. We previously demonstrated the induction of apoptosis by esculetin in NB4 human leukemia cells, as a model, by a mechanism not well understood. To analyse the antioxidant activity of esculetin on apoptosis, we have studied the influence of co-treatments of esculetin at a concentration of 100μM with exogenous ROS donors, namely tert-butyl-hydroperoxide and hydrogen peroxide, on NB4 cells. Esculetin (100μM) exerts a protective effect on cell viability and...
Source: Experimental and Toxicologic Pathology - September 12, 2017 Category: Pathology Authors: Virginia Rubio Ana Isabel Garc ía-Pérez Angel Herr áez M Cristina Tejedor Jos é C Diez Source Type: research