Antimicrobial resistance monitoring in the Danish swine production by phenotypic methods and metagenomics from 1999 to 2018
ConclusionWe validated the long-term usefulness of indicator bacteria and showed that metagenomics is a promising approach for AMR surveillance. (Source: Eurosurveillance)
Source: Eurosurveillance - May 18, 2023 Category: Infectious Diseases Authors: Ana Sofia R. Duarte, Ana Rita Marques, Vibe D. Andersen , Helle B. Korsgaard, Hanne Mordhorst, Frederik D. M øller, Thomas N. Petersen, Håkan Vigre, Tine Hald and Frank M. Aarestrup Source Type: research

Clinical epidemiology and case fatality due to antimicrobial resistance in Germany: a systematic review and meta-analysis, 1 January 2010 to 31 December 2021
ConclusionContinuous efforts in AMR surveillance and infection prevention and control as well as antibiotic stewardship are needed to limit the spread of AMR in Germany. (Source: Eurosurveillance)
Source: Eurosurveillance - May 18, 2023 Category: Infectious Diseases Authors: Maria R ödenbeck, Olaniyi Ayobami, Tim Eckmanns, Mathias W Pletz, Jutta Bleidorn and Robby Markwart Source Type: research

Associated deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in Switzerland, 2010 to 2019
ConclusionsThe AMR burden estimate in Switzerland has increased significantly between 2010 and 2019. Considerable differences depending on the linguistic region and the hospital type were identified– a finding which affects the nationwide burden estimation. (Source: Eurosurveillance)
Source: Eurosurveillance - May 18, 2023 Category: Infectious Diseases Authors: Michael Gasser, Alessandro Cassini, Danilo Lo Fo Wong, Marcello Gelormini, Saskia Andrea Nahrgang, Walter Zingg and Andreas Oskar Kronenberg Source Type: research

Avian influenza, new aspects of an old threat
(Source: Eurosurveillance)
Source: Eurosurveillance - May 11, 2023 Category: Infectious Diseases Authors: Cornelia Adlhoch and Francesca Baldinelli Source Type: research

Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022
Whole genome sequencing data of 874Escherichia coli isolates carryingblaNDM-5 from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidrug-resistant. Further spread ofE. coli carryingblaNDM-5 would leave limited treatment options for seriousE. coli infections. (Source: Eurosurveillance)
Source: Eurosurveillance - May 11, 2023 Category: Infectious Diseases Authors: Marius Linkevicius, R émy A Bonnin, Erik Alm, Olov Svartström, Petra Apfalter, Rainer Hartl, Henrik Hasman, Louise Roer, Kati Räisänen, Laurent Dortet, Niels Pfennigwerth, Jörg B Hans, Ákos Tóth, Lilla Buzgó, Martin Cormican, Niall Delappe, Monica Source Type: research

Evaluating the effect of targeted strategies as control tools for hypervirulent meningococcal C outbreaks: a case study from Tuscany, Italy, 2015 to 2016
ConclusionsOur findings suggest that there are no effective alternatives to widespread reactive vaccination during outbreaks of highly transmissible MenC strains. Age-targeted campaigns can increase the effectiveness of vaccination campaigns. These results can be instrumental to define effective guidelines for the control of future meningococcal outbreaks caused by hypervirulent strains. (Source: Eurosurveillance)
Source: Eurosurveillance - May 11, 2023 Category: Infectious Diseases Authors: Giorgio Guzzetta, Marco Ajelli, Alessandro Miglietta, Cecilia Fazio, Arianna Neri, Stefano Merler, Giovanni Rezza and Paola Stefanelli Source Type: research

Hepatitis A notifications in the EU/EEA, 2010 –2019: what can we learn from case reporting to the European Surveillance System?
DiscussionApart from some countries in its east, the EU/EEA is characterised by low HepA incidence baseline and susceptible to recurrent large cross-border outbreaks. Analysis of European surveillance data highlighted the need for stronger prevention policies for eastern EU countries, men who have sex with men and travellers. Improving surveillance data-quality will enhance knowledge on food-borne, and travel-related exposures to inform more effective and tailored regional prevention policies. (Source: Eurosurveillance)
Source: Eurosurveillance - May 11, 2023 Category: Infectious Diseases Authors: Ettore Severi, Lara Tavoschi, Paloma Carrillo-Santisteve, Therese Westrell, Gaetano Marrone, Johan Giesecke and Pierluigi Lopalco Source Type: research

Antimicrobial resistance of clinical Enterobacterales isolates from urine samples, Germany, 2016 to 2021
ConclusionsResistance has generally decreased over the past years, independent of sex, age and causative pathogen. Our data provide an important basis for empirical antibiotic recommendations in various settings and patient collectives. (Source: Eurosurveillance)
Source: Eurosurveillance - May 11, 2023 Category: Infectious Diseases Authors: Carolin Stoltidis-Claus, Kerstin Daniela Rosenberger, Falitsa Mandraka, Xenia Quante, J örg Gielen, Dennis Hoffmann, Hilmar Wisplinghoff and Nathalie Jazmati Source Type: research

Serosurveillance of SARS-CoV-2 in Welsh Blood Donors: Establishment of the surveillance system and results up to November 2022
ConclusionWe successfully set up long-term serological surveillance of SARS-CoV-2 using residual samples from blood donations, demonstrating variation based on age, ethnicity and location. (Source: Eurosurveillance)
Source: Eurosurveillance - May 11, 2023 Category: Infectious Diseases Authors: Sophie Harker, Si ân Elizabeth James, James Murphy, Ben Davies, Catherine Moore, Brian P Tennant, John Geen and Daniel Thomas Source Type: research

SARS-CoV-2 self-test uptake and factors associated with self-testing during Omicron BA.1 and BA.2 waves in France, January to May 2022
ConclusionThe analysis showed high self-test uptake in France with some inequalities which must be addressed through education and facilitated access (cost and availability) for making it a more efficient epidemic control tool. (Source: Eurosurveillance)
Source: Eurosurveillance - May 4, 2023 Category: Infectious Diseases Authors: Olivier Supplisson, Tiffany Charmet, Simon Galmiche, Laura Schaeffer, Olivia Ch ény, Anne Lévy, Nathan Jeandet, Faïza Omar, Christophe David, Alexandra Mailles and Arnaud Fontanet Source Type: research

The role of children in transmission of SARS-CoV-2 variants of concern within households: an updated systematic review and meta-analysis, as at 30 June 2022
ConclusionsThese data suggest that the emergence of VOC was associated with a fundamental shift in the epidemiology of SARS-CoV-2. It is unlikely that this is solely the result of age-dependent differences in vaccination during the VOC period and may instead reflect virus evolution over the course of the pandemic. (Source: Eurosurveillance)
Source: Eurosurveillance - May 4, 2023 Category: Infectious Diseases Authors: Yanshan Zhu, Yao Xia, Janessa Pickering, Asha C Bowen and Kirsty R Short Source Type: research

Tick-borne encephalitis epidemiology and surveillance in Poland, and comparison with selected European countries before and during the COVID-19 pandemic, 2008 to 2020
ConclusionThe sensitivity of TBE surveillance in Poland requires improvement. There are considerable regional differences. Regions that test for TBE intensively report most cases. Policymakers should be made aware of the value of quality epidemiological data for planning prophylactic measures in risk areas. (Source: Eurosurveillance)
Source: Eurosurveillance - May 4, 2023 Category: Infectious Diseases Authors: Iwona Paradowska-Stankiewicz, Katarzyna Pancer, Anna Pozna ńska, Martyna Hordowicz, Maria Skibicka, Marek Słowiński, Gerard Motak and Bogdan Falkiewicz Source Type: research

Erratum for Euro Surveill. 2023;28(15)
(Source: Eurosurveillance)
Source: Eurosurveillance - April 27, 2023 Category: Infectious Diseases Authors: Eurosurveillance editorial team Source Type: research

Lack of seroprotection against diphtheria in the Austrian population, in light of reported diphtheria cases in Europe, 2022
Following an increase in diphtheria cases in Europe since 2022, we retrospectively estimated the prevalence of seroprotection against diphtheria and tetanus in 10,247 Austrian residents (population: 8,978,929) voluntarily tested between 2018 and 2022. Lack of seroprotection against diphtheria was found in 36% compared with 4% against tetanus. The geometric mean antibody concentration against tetanus was 7.9-fold higher compared with that for diphtheria. Raising awareness of regular booster vaccinations against diphtheria in combination with tetanus and pertussis is urgently needed. (Source: Eurosurveillance)
Source: Eurosurveillance - April 27, 2023 Category: Infectious Diseases Authors: Angelika Wagner, Joanna Jasinska, Daniela Schmid, Michael Kundi and Ursula Wiedermann Source Type: research

Within-patient horizontal transfer of pOXA-48 from a hypervirulent Klebsiella pneumoniae SL218 to Serratia marcescens following spread of the K. pneumoniae isolate among hospitalised patients, Denmark, 2021
A hypervirulentKlebsiella pneumoniae SL218 (ST23-KL57), phylogenetically distinct from the classical hypervirulent SL23 (ST23-KL1) lineage, was transmitted between hospitalised patients in Denmark in 2021. The isolate carried a hybrid resistance and virulence plasmid containingblaNDM-1 and a plasmid containingblaOXA-48 (pOXA-48); the latter plasmid was horizontally transferred within-patient toSerratia marcescens. The convergence of drug resistance and virulence factors in single plasmids and in different lineages ofK. pneumoniae is concerning and requires surveillance. (Source: Eurosurveillance)
Source: Eurosurveillance - April 27, 2023 Category: Infectious Diseases Authors: Karen Leth Nielsen, Marc S ørensen, Frederik Boëtius Hertz, Maria Anna Misiakou, Henrik Hasman, Susanne Häussler, Marie Helleberg and Kristian Schønning Source Type: research