Enhanced recovery after surgery pathway with modified biportal endoscopic transforaminal lumbar interbody fusion using a large cage. Comparative study with minimally invasive microscopic transforaminal lumbar interbody fusion
ConclusionBiportal endoscopic TLIF with ERAS pathway may have good aspect to accelerate recovery after surgery. There was no inferiority of fusion rate of endoscopic TLIF comparing to microscopic TLIF. Biportal endoscopic TLIF using a large cage with ERAS pathway may be a good alternative treatment for lumbar degenerative disease. (Source: European Spine Journal)
Source: European Spine Journal - May 21, 2023 Category: Orthopaedics Source Type: research

Influence of the preoperative L5S1 disc state on lateral L2 to L5 fusion ’s outcomes at an average follow-up of 3,5 years (minimum 2 years)
ConclusionA preop L5S1 disc degeneration does not seem to impact the final clinical outcomes after lumbar lateral interbody fusion at a minimal two years F.U. It should not be systematically involved in an overlying fusion. (Source: European Spine Journal)
Source: European Spine Journal - May 20, 2023 Category: Orthopaedics Source Type: research

Efficacy of perioperative gabapentin use in patients with idiopathic scoliosis undergoing fusion surgery: a systematic review and meta-analysis
ConclusionsGabapentin decreased opioid consumption during the first 48  h. Doses of 15 mg/kg showed superiority in reducing opioid consumption in the first 48 h.Level of evidence IDiagnostic: individual cross-sectional studies with consistently applied reference standard and blinding. (Source: European Spine Journal)
Source: European Spine Journal - May 20, 2023 Category: Orthopaedics Source Type: research

Clinical differences in preoperative symptoms and surgical outcomes between early and late-teen patients with Lenke type 5C adolescent idiopathic scoliosis
ConclusionIn patients with Lenke type 5C AIS, we showed that late teens had significantly worse SRS-22r scores than did early teens. Postoperative coronal malalignment was frequently observed in the late teens due to the reduced ability of compensation by subjacent disc wedging. (Source: European Spine Journal)
Source: European Spine Journal - May 20, 2023 Category: Orthopaedics Source Type: research

Raftlin and 8-iso-prostaglandin F2 α levels and gene network analysis in patients with Modic changes
ConclusionOur findings indicated that oxidative stress in patients with MC-I may be aggravated and it may cause an inflammation formation of the lesion areas in these patients. Also, the increased 8-iso-PGF2 α and Raftlin levels in patients with MC-II and MC-III may be an adaptive response to against oxidative stress. (Source: European Spine Journal)
Source: European Spine Journal - May 19, 2023 Category: Orthopaedics Source Type: research

Outcomes of different zero-profile spacers in the treatment of two-level cervical degenerative disk disease
ConclusionsZero-profile spacers showed promising clinical outcomes in CDDD patients having contiguous two-level ACDF. However, ROI-C resulted in a higher intervertebral space height loss and a higher cage subsidence rate than anchor-C during the follow-up. (Source: European Spine Journal)
Source: European Spine Journal - May 17, 2023 Category: Orthopaedics Source Type: research

Description of age-related changes in cervical sagittal alignment based on pelvic incidence classification in asymptomatic Chinese population
ConclusionThis study showed the PI- and age-related cervical alignment changes of Chinese healthy population. Based on the classification in our study, high or low PI apparently did not correlate with the occurrence of cervical degenerative disease. (Source: European Spine Journal)
Source: European Spine Journal - May 17, 2023 Category: Orthopaedics Source Type: research

The importance of inflammatory biomarkers in non-specific acute and chronic low back pain: a systematic review
ConclusionsThis systematic review found evidence of increased levels of pro-inflammatory biomarkers CRP, IL-6 and TNF- α and decreased levels of anti-inflammatory biomarker IL-10 in patients with LBP. Hs-CRP was not correlated with LBP. There is insufficient evidence to associate these findings with the degree of pain severity or the activity status of the lumbar pain over time. (Source: European Spine Journal)
Source: European Spine Journal - May 17, 2023 Category: Orthopaedics Source Type: research

Machine learning for the prediction of postoperative nosocomial pulmonary infection in patients with spinal cord injury
ConclusionAge, ASIA scale and tracheotomy were the independent risk factors of postoperative nosocomial pulmonary infection in SCI. The prediction model based on RF algorithm had the best performance. (Source: European Spine Journal)
Source: European Spine Journal - May 17, 2023 Category: Orthopaedics Source Type: research

Ultrashort time-to-echo MR morphology of cartilaginous endplate correlates with disc degeneration in the lumbar spine
ConclusionThese results suggest that abnormal CEPs are frequently found, and it associates significantly with disc degeneration, suggesting an insight into pathoetiology of disc degeneration. (Source: European Spine Journal)
Source: European Spine Journal - May 17, 2023 Category: Orthopaedics Source Type: research

An improved total en bloc spondylectomy for L5 vertebral giant cell tumor through a single-stage posterior approach
ConclusionSingle-stage posterior TES for L5 GCT was previously considered impossible. In this study, we presented our experience with the use of an improved surgical technique for L5 TES through the single-stage posterior approach, which has proved to be superior to the conventional procedures in terms of blood loss control and complication and recurrence rates.Level of EvidenceIV. (Source: European Spine Journal)
Source: European Spine Journal - May 16, 2023 Category: Orthopaedics Source Type: research

The relationship between frailty and spinal alignment in the elderly general population: a two-year longitudinal study
ConclusionFrailty was associated with a worsening in global alignment along the 2- year follow up. The frailty may begin with a decrease in activity and progression of exhaustion; preventing this progression is important through motivation to exercise.Level of evidenceII (Source: European Spine Journal)
Source: European Spine Journal - May 16, 2023 Category: Orthopaedics Source Type: research

Intraoperative cell-salvaged autologous blood transfusion is safe in metastatic spine tumour surgery: early outcomes of prospective clinical study
ConclusionsPatients of SBT had OS and tumour progression better than ABT/NBT groups. This is the first prospective study to report of SBT in comparison with control groups in MSTS. (Source: European Spine Journal)
Source: European Spine Journal - May 16, 2023 Category: Orthopaedics Source Type: research

Software-assisted preoperative planning of S1 Alar Iliac screws: a 3D morphometric and anatomical study
ConclusionPreoperative 3D modeling would be an invaluable adjunct to increase the accuracy of S1AI screw placement. Surgeon ’s perspective of the trajectory differs from standard CT sections and should be considered in preoperative planning. (Source: European Spine Journal)
Source: European Spine Journal - May 14, 2023 Category: Orthopaedics Source Type: research

Novel 3D printable PEEK-HA-Mg2SiO4 composite material for spine implants: biocompatibility and imaging compatibility assessments
ConclusionComposite A demonstrated superior bioactivity vs PEEK and PEEK-HA materials and comparable imaging compatibility vs PEEK and PEEK-HA. Therefore, our material displays an excellent potential to manufacture spine implants with enhanced mechanical and bioactive property. (Source: European Spine Journal)
Source: European Spine Journal - May 13, 2023 Category: Orthopaedics Source Type: research