European Review for Medical and Pharmacological Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

High triglyceride-glucose index is associated with low postoperative satisfaction in patients with posterior instrumented lumbar fusion
CONCLUSIONS: In patients who underwent posterior lumbar instrumentation and fusion surgery, a high preoperative TyG index may predict poor postoperative ODI and PF scores, indicating lower patient satisfaction.PMID:38567605 | DOI:10.26355/eurrev_202403_35750 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: V K ıyak Source Type: research

The CRISPR-Cas9 induced CCR5 Δ32 mutation as a potent gene therapy methodology for resistance to HIV-1 variant: a review
Eur Rev Med Pharmacol Sci. 2024 Mar;28(6):2430-2463. doi: 10.26355/eurrev_202403_35751.ABSTRACTHuman Immunodeficiency Virus (HIV) has continuously been the greatest epidemic for humanity over a period spanning almost five decades. With no specific cure or treatment available to date despite extensive research, the C-C Chemokine Receptor 5, Delta 32 (CCR5 Δ32) allele genetic point mutation plays an imperative role in the prevention of acquired immunodeficiency syndrome (AIDS). This comprehensive study aims to review the induction of the homozygous recessive deletion genotype using the Clustered Regularly Interspaced Short ...
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: M Saifullah O Laghzaoui H Ozyahyalar A Irfan Source Type: research

Association of SOD1 gene variants (50 bp Ins/Del, rs4817415, rs2070424, rs1041740, rs17880135) with plasma protein levels in vitiligo patients and their analysis in silico
CONCLUSIONS: Information regarding the pathogenesis of vitiligo helps recognize risk factors and identify the relationship of diagnostic markers of cell damage inherent to the disease. This will help improve aspects of prevention and the choice of treatment alternatives appropriate to each case.PMID:38567607 | DOI:10.26355/eurrev_202403_35752 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: B C G ómez-Meda G M Z úñiga-González L D Ba ñuelos-Díaz M P Oceguera-Angel A Galindo-G ómez M G S ánchez-Parada A F Garibaldi-R íos B M Torres-Mendoza A L Zamora-Perez J I Delgado-Saucedo M G M árquez-Rosales M P Gallegos-Arreola Source Type: research

Effects of different doses of remimazolam on hemodynamics during general anesthesia in patients with septic shock
CONCLUSIONS: Remimazolam is safe and effective for inducing general anesthesia in patients with septic shock. Low, medium, and high doses of remimazolam can maintain a stable hemodynamic state, and the recovery of hepatic and renal function is certain to depend on the dose.PMID:38567608 | DOI:10.26355/eurrev_202403_35755 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: Q-C Dai J-L Zhao X-Y Miao R Wang Z Hui Source Type: research

Effect of intravenous and topical laryngeal lidocaine on sore throat after extubation: a prospective randomized controlled study
CONCLUSIONS: Both topical laryngeal lidocaine and intravenous lidocaine before intubation have positive effects on preventing sore throat. Topical laryngeal route was superior to intravenous route. Chictr.org.cn ID: ChiCTR2100042442.PMID:38567609 | DOI:10.26355/eurrev_202403_35756 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: J Lin W-D Wang Q-Y Yang Y-L Wen J-H Yang W-Q Fan Y-B Zuo Source Type: research

Dexmedetomidine protects the uterus against ischemia-reperfusion injury in rats
CONCLUSIONS: In our study, it has been documented that dexmedetomidine protects the uterine tissue against ischemia-reperfusion injury.PMID:38567610 | DOI:10.26355/eurrev_202403_35757 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: V K ölükçü M G ürler Balta H Tapar T Karaman S Karaman V Unsal F Gevrek M Katar Source Type: research

Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research

Potential acetylcholinesterase inhibitors to treat Alzheimer's disease
CONCLUSIONS: This study found that Z-9 (Fluoroquinolones) and TBAF-6 (benzimidazole-benzothiazole) compounds improve behavioral and biochemical parameters, thus treating neurodegenerative disorders effectively.PMID:38567612 | DOI:10.26355/eurrev_202403_35759 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: A Saud V Krishnaraju A Taha K Kalpana V Malarkodi S Durgaramani V Vinoth Prabhu F A Saleh S Ezhilarasan Source Type: research

Effects of adenosine triphosphate, Lacidipine, and Benidipine on 5-fluorouracil-induced kidney damage in rats
CONCLUSIONS: It may be possible to prevent nephrotoxicity by adding ATP + Benidipine or ATP to 5-FU treatment.PMID:38567613 | DOI:10.26355/eurrev_202403_35760 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: T Dagel D Altuner B Suleyman R Mammadov S Bulut T Bal Tastan M Gulaboglu H Suleyman Source Type: research

A comparative perspective on brucellar, pyogenic, and tuberculous spondylodiscitis
CONCLUSIONS: Weight loss, painless palpation, involved thoracic spine, psoas abscess, and neurologic deficit are symptoms favoring tuberculous spondylodiscitis. History of spine surgery, high fever, skin erythema, and paraspinal abscess are findings in favor of pyogenic spondylodiscitis. Rural living, sweating, and involved lumbar spine are symptoms that indicate brucellar spondylodiscitis. These symptoms can be used to distinguish the types of spondylodiscitis.PMID:38567614 | DOI:10.26355/eurrev_202403_35761 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: A I Baran M Celik Y Arslan S Incecik I Binici M Toprak M Sunnetcioglu Source Type: research

Analysis of candidemia cases in a city hospital during the COVID-19 pandemic
CONCLUSIONS: As our study observed, the COVID-19 pandemic brought increasing numbers of immunosuppressed patients, widespread use of antibacterials, and central venous catheters, increasing the frequency and mortality of candidemia cases. All health institutions should be prepared for the diagnosis and treatment of candidemia. In addition, C. auris, the frequency of which has increased in recent years, is a new factor that should be considered in candidemia cases.PMID:38567615 | DOI:10.26355/eurrev_202403_35762 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: O Ozalp S Komec M Unsel A Gunduz O Altuntas Aydin Source Type: research

Severity of COVID-19 manifestations in HIV patients: a systematic review and meta-analysis
CONCLUSIONS: PLWHs and HIV-negative individuals showed comparable rates and intensity of COVID-19. ART users exhibited immunological health comparable to immunocompetent people, demonstrating the essential role of ART in reducing the severity and mortality of PLWH with COVID-19.PMID:38567616 | DOI:10.26355/eurrev_202403_35763 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: A Alam A A Soeroto R A Susilohadi L A Chandra Source Type: research

Evaluation of vaccine effectiveness of mRNA COVID-19 vaccines in children: a systematic review and meta-analysis
CONCLUSIONS: Both partial and full immunization of the BNT162b2 mRNA vaccine provide benefits in reducing infection rates. VE varies over time and is closely associated with viral mutations and waning immunity. The specific mechanisms require further investigation.PMID:38567617 | DOI:10.26355/eurrev_202403_35764 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: Y-H Hu Y Ding L-W Li J Cheng Y-H Cai Source Type: research

Post-COVID syndrome: analysis of the prevalence of chemosensory dysfunction and predictive factors of recovery in COVID-19 long-haulers in Jordan
CONCLUSIONS: Chemosensory dysfunctions are largely subjective; therefore, more objective examinations are required to draw more definite conclusions.PMID:38567618 | DOI:10.26355/eurrev_202403_35765 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: H M Sawan A H Khalifeh M Ahmed M M Khalil S M Al Omari R Binsuwaidan Source Type: research

Evaluation of the hematological and immunological markers after the first and second doses of BNT162b2 mRNA vaccine
CONCLUSIONS: We can conclude that the Pfizer/BioNTech vaccine produced a more potent T-cell response than humoral ones.PMID:38567619 | DOI:10.26355/eurrev_202403_35766 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: M Rafeeq M S Jabir H M Al-Kuraishy Z M A Jeddoa S F Jawad M A A Najm A F Almulla E Elekhnawy J Z Tayyeb A Turkistani B A Alsfouk G E Batiha Source Type: research