Ear and upper airway clinical outcome measures for use in primary ciliary dyskinesia research: a scoping review
Conclusions
This scoping review highlights the lack of data regarding ear and upper airway outcomes in PCD. It also reports a high heterogeneity in outcome definitions or measures. We provide well-founded specific suggestions to standardise ear and upper airway outcome definitions and reporting for future PCD research studies. (Source: European Respiratory Review)
Source: European Respiratory Review - July 12, 2023 Category: Respiratory Medicine Authors: Alexandru, M., Veil, R., Rubbo, B., Goutaki, M., Kim, S., Lam, Y. T., Nevoux, J., Lucas, J. S., Papon, J.-F. Tags: Respiratory clinical practice, Paediatric pulmonology Reviews Source Type: research
Physical activity measurements in individuals with interstitial lung disease: a systematic review and meta-analysis
Conclusion
The use of activity monitors and questionnaires in ILD lacks consistency. Improvement is required in the reporting quality of PA measurement methods using activity monitors. (Source: European Respiratory Review)
Source: European Respiratory Review - July 12, 2023 Category: Respiratory Medicine Authors: Iwakura, M., Kawagoshi, A., Tamaki, A., Oki, Y., Oshima, Y., Spruit, M. A. Tags: Interstitial and orphan lung disease Reviews Source Type: research
"Noninvasive respiratory support after extubation: a systematic review and network meta-analysis".A. Boscolo, T. Pettenuzzo, N. Sella, M. Zatta, M. Salvagno, M. Tassone, C. Pretto, A. Peralta, L. Muraro, F. Zarantonello, A. Bruni, F. Geraldini, A. De Cassai and P. Navalesi. Eur Respir Rev 2023; 32: 220196.
(Source: European Respiratory Review)
Source: European Respiratory Review - June 21, 2023 Category: Respiratory Medicine Tags: Author correction Source Type: research
The role of oral appliance therapy in obstructive sleep apnoea
There is now widespread recognition within the world of sleep medicine of the increasing importance of dental sleep medicine and, in particular, the role of oral appliance therapy (OAT) in the management of adults with obstructive sleep apnoea (OSA). For the purpose of this review, the term OAT refers to a custom-made intra-oral appliance, which acts to posture the mandible in a forward and downward direction, away from its natural resting position. Whilst nasally applied continuous positive airway pressure remains the "gold standard" in nonsurgical OSA management, OAT remains the recognised alternative treatment.
This rev...
Source: European Respiratory Review - June 21, 2023 Category: Respiratory Medicine Authors: Johal, A., Hamoda, M. M., Almeida, F. R., Marklund, M., Tallamraju, H. Tags: Sleep medicine Reviews Source Type: research
Meditative movement for breathlessness in advanced COPD or cancer: a systematic review and meta-analysis
In conclusion, in people with advanced COPD or cancer, meditative movement does not improve breathlessness, health-related quality of life or exercise capacity. Methodological limitations lead to low levels of certainty in the results. (Source: European Respiratory Review)
Source: European Respiratory Review - June 21, 2023 Category: Respiratory Medicine Authors: Nolan, C. M., Brighton, L. J., Mo, Y., Bayly, J., Higginson, I. J., Man, W. D.-C., Maddocks, M. Tags: COPD and smoking, Respiratory clinical practice, Lung cancer Reviews Source Type: research
Barriers to and facilitators of populational adherence to prevention and control measures of COVID-19 and other respiratory infectious diseases: a qualitative evidence synthesis
Conclusions:
This review suggests that financial and social support, assertive communication, trust in political authorities and greater regulation of social media enhance adherence to prevention and control measures for COVID-19 and infectious respiratory diseases. Designing and implementing effective educational public health interventions targeting the findings of barriers and facilitators highlighted in this review are key to reducing the impact of infectious respiratory diseases at the population level. (Source: European Respiratory Review)
Source: European Respiratory Review - June 21, 2023 Category: Respiratory Medicine Authors: Zaildo, T., Santino, T. A., Chaves, G., da Silva, B. A. K., Alchieri, J. C., Patino, C. M., Leite, S., Luz, K. G., Guerra, R. O., da Penha, T. H. S., da Silva, G. R., Jacome, A. C., Monteiro, K. S., de Mendonca, K. M. P. P. Tags: Respiratory infections and tuberculosis Reviews Source Type: research
Clinical utility of WHO-recommended screening tools and development and validation of novel clinical prediction models for pulmonary tuberculosis screening among outpatients living with HIV: an individual participant data meta-analysis
Conclusions:
CRP sets the standard for tuberculosis screening among outpatient PLHIV. The choice between using CRP at 5 mg·L–1 cut-off or in a CPM depends on available resources. (Source: European Respiratory Review)
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Authors: Dhana, A., Gupta, R. K., Hamada, Y., Kengne, A. P., Kerkhoff, A. D., Yoon, C., Cattamanchi, A., Reeve, B. W. P., Theron, G., Ndlangalavu, G., Wood, R., Drain, P. K., Calderwood, C. J., Noursadeghi, M., Boyles, T., Meintjes, G., Maartens, G., Barr, D. A. Tags: Respiratory infections and tuberculosis Reviews Source Type: research
Extreme weather and asthma: a systematic review and meta-analysis
Conclusions:
Our study showed that extreme weather events more prominently increased the risk of asthma morbidity and mortality in children and females. Climate change is a critical concern for asthma control. (Source: European Respiratory Review)
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Authors: Makrufardi, F., Manullang, A., Rusmawatiningtyas, D., Chung, K. F., Lin, S.-C., Chuang, H.-C. Tags: Asthma and allergy Reviews Source Type: research
Basic, translational and clinical aspects of bronchiectasis in adults
Bronchiectasis is a common progressive respiratory disease with recognisable radiological abnormalities and a clinical syndrome of cough, sputum production and recurrent respiratory infections. Inflammatory cell infiltration into the lung, in particular neutrophils, is central to the pathophysiology of bronchiectasis. Herein we explore the roles and relationships between infection, inflammation and mucociliary clearance dysfunction in the establishment and progression of bronchiectasis. Microbial and host-mediated damage are important processes underpinning bronchiectasis and the relative contribution of proteases, cytokin...
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Authors: Chalmers, J. D., Elborn, S., Greene, C. M. Tags: CF and non-CF bronchiectasis Reviews Source Type: research
The role of diet and nutrition in the management of COPD
In 2014, the European Respiratory Society published a statement on nutritional assessment and therapy in COPD. Since then, increasing research has been performed on the role of diet and nutrition in the prevention and management of COPD. Here, we provide an overview of recent scientific advances and clinical implications. Evidence for a potential role of diet and nutrition as a risk factor in the development of COPD has been accumulating and is reflected in the dietary patterns of patients with COPD. Consuming a healthy diet should, therefore, be promoted in patients with COPD. Distinct COPD phenotypes have been identified...
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Authors: Beijers, R. J. H. C. G., Steiner, M. C., Schols, A. M. W. J. Tags: COPD and smoking, Respiratory clinical practice Nonpharmacological interventions in COPD: state of the art and future directions Source Type: research
"Strength of association between comorbidities and asthma: a meta-analysis" Paola Rogliani, Rossella Laitano, Josuel Ora, Richard Beasley and Luigino Calzetta. Eur Respir Rev 2023; 32: 220202
(Source: European Respiratory Review)
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Tags: Author correction Source Type: research
Deep learning for pneumothorax diagnosis: a systematic review and meta-analysis
Conclusions
Our review found the diagnostic performance of DL models was similar to that of physicians, although the majority of studies had a high risk of bias. Further pneumothorax AI research is needed. (Source: European Respiratory Review)
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Authors: Sugibayashi, T., Walston, S. L., Matsumoto, T., Mitsuyama, Y., Miki, Y., Ueda, D. Tags: Lung imaging, Respiratory clinical practice Reviews Source Type: research
Pulmonary rehabilitation and physical interventions
Pulmonary rehabilitation has established a status of evidence-based therapy for patients with symptomatic COPD in the stable phase and after acute exacerbations. Rehabilitation should have the possibility of including different disciplines and be offered in several formats and lines of healthcare. This review focusses on the cornerstone intervention, exercise training, and how training interventions can be adapted to the limitations of patients. These adaptations may lead to altered cardiovascular or muscular training effects and/or may improve movement efficiency. Optimising pharmacotherapy (not the focus of this review) ...
Source: European Respiratory Review - June 7, 2023 Category: Respiratory Medicine Authors: Troosters, T., Janssens, W., Demeyer, H., Rabinovich, R. A. Tags: COPD and smoking, Respiratory clinical practice Nonpharmacological interventions in COPD: state of the art and future directions Source Type: research
Efficacy and safety of gefapixant for chronic cough: a meta-analysis of randomised controlled trials
Conclusions
This meta-analysis revealed dose-dependent efficacy and adverse effects of gefapixant against chronic cough. Further studies are required to investigate the feasibility of moderate-dose (i.e. 45–50 mg twice daily) gefapixant in clinical practice. (Source: European Respiratory Review)
Source: European Respiratory Review - May 17, 2023 Category: Respiratory Medicine Authors: Chuang, M.-H., Chen, I.-W., Chen, J.-Y., Kang, F.-C., Ho, C.-N., Wu, S.-C., Yew, M., Lan, K.-M., Hung, K.-C. Tags: Pulmonary pharmacology and therapeutics, Respiratory clinical practice Reviews Source Type: research
Phenotype overlap in the natural history of asthma
The heterogeneity of asthma makes it challenging to unravel the pathophysiologic mechanisms of the disease. Despite the wealth of research identifying diverse phenotypes, many gaps still remain in our knowledge of the disease's complexity. A crucial aspect is the impact of airborne factors over a lifetime, which often results in a complex overlap of phenotypes associated with type 2 (T2), non-T2 and mixed inflammation. Evidence now shows overlaps between the phenotypes associated with T2, non-T2 and mixed T2/non-T2 inflammation. These interconnections could be induced by different determinants such as recurrent infections,...
Source: European Respiratory Review - May 17, 2023 Category: Respiratory Medicine Authors: Ricciardolo, F. L. M., Guida, G., Bertolini, F., Di Stefano, A., Carriero, V. Tags: Asthma and allergy Reviews Source Type: research
