Prognostic and clinical significance of syndecan-1 expression in breast cancer: A systematic review and meta-analysis
Publication date: Available online 25 December 2018Source: European Journal of Surgical OncologyAuthor(s): Weiqiang Qiao, Heyang Liu, Wanying Guo, Peng Li, Miao DengAbstractBackgroundThe prognostic value of syndecan-1 (SDC1, also called CD138) in breast cancer remains controversial. Therefore, we performed a meta-analysis to assess the clinical significance of SDC1 expression in breast cancer.Materials and methodsVarious databases were searched to evaluate possible correlations between SDC1 protein or mRNA expression and prognostic significance in breast cancer. Pooled hazard ratios (HRs) and odds ratios (ORs) with 95% con...
Source: European Journal of Surgical Oncology (EJSO) - December 25, 2018 Category: Surgery Source Type: research

Isolated Langerhans islets: Potential pitfall in solid and pseudopapillary neoplasm resection?
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Adriana Handra-Luca (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Survival comparison in gastric cancer patients between 7th and 8th edition of the AJCC TNM staging system: The first western single center experience
ConclusionRestaging system seems to improve survival rate discrimination in particular comparing stage IIIB and stage IIIC; whereas in stage IIIA this is not so clear.More studies are necessary to confirm these data. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Liver resection is justified for multinodular hepatocellular carcinoma in selected patients with cirrhosis a multicenter analysis of 1,066 patients
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Zhen-Li Li, Jiong-Jie Yu, Jun-Wu Guo, Cheng-Jun Sui, Bing-Hua Dai, Wan-Guang Zhang, Ting-Hao Chen, Chao Li, Wei-Min Gu, Ya-Hao Zhou, Hong Wang, Yao-Ming Zhang, Xian-Hai Mao, Timothy M. Pawlik, Ming-Da Wang, Lei Liang, Han Wu, Wan Yee Lau, Meng-Chao Wu, Feng ShenAbstractBackgroundThe role of liver resection for multinodular (≥3 nodules) hepatocellular carcinoma (HCC) remains unclear, especially among patients with severe underlying liver disease. We sought to evaluate surgical outcomes among patients with cirrhosis ...
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

FDG-avid presacral soft tissue mass in previously treated rectal cancer: Diagnostic outcome and additional value of MRI, including diffusion-weighted imaging
ConclusionsFDG-PET/CT has a poor PPV for locally recurrent rectal cancer in the presacral space. The observation of air in the FDG-avid presacral lesion and additional MRI assessment are diagnostically helpful, without a significant additional value of DWI. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

A new nomogram for recurrence-free survival prediction of gastrointestinal stromal tumors: Comparison with current risk classification methods
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Tao Chen, Lili Xu, Liangying Ye, Haibo Qiu, Yanfeng Hu, Hao Liu, Zhiwei Zhou, Guoxin Li, Jiang YuAbstractBackgroundGastrointestinal stromal tumors (GISTs) focused on a popular factor Ki-67 to enable individualized and precise predictions of the most suitable candidates for imatinib therapy.MethodsWe retrospectively collected clinicopathologic data of the patients diagnosed with GISTs from January 1998 to December 2015 at Southern Medical University Nanfang Hospital as the experiment group. And patients with GISTs at...
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Acute malignant obstruction in patients with peritoneal carcinomatosis: The role of palliative surgery
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Nadine L. de Boer, Jan A.W. Hagemans, Bob T.A. Schultze, Alexandra R.M. Brandt-Kerkhof, Eva V.E. Madsen, Cornelis Verhoef, Jacobus W.A. BurgerAbstractIntroductionPatients with peritoneal carcinomatosis who do not have curative treatment options often develop acute obstructive symptoms and when conservative management fails, surgical treatment is the remaining option. However, palliative surgery is associated with high morbidity and mortality and the chance of success is unclear. The aim of this study was to evaluate o...
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Evaluation of the MDACC clinical classification system for pancreatic cancer patients in an European multicenter cohort
This study intents to evaluate the proposed borderline classification system in a multicenter patient cohort without neoadjuvant treatment.MethodsEvaluation was based on a multicenter database of pancreatic cancer patients undergoing surgery from 2005 to 2016 (n = 1020). Complications were classified based on the Clavien-Dindo classification. χ2-test, Kaplan–Meier estimator and Cox regression hazard model were used for statistical analysis.ResultsMost patients (55.1%) were assigned as type A patients, followed by type C (35.8%) and type B patients (9.1%). Neither the complication rate, nor the mortality rate ...
Source: European Journal of Surgical Oncology (EJSO) - December 20, 2018 Category: Surgery Source Type: research

ypT0N+ status in oesophageal cancer patients: Location of residual metastatic lymph nodes with regard to the neoadjuvant radiation field
ConclusionMost ypT0N + lymph nodes are located within the neoadjuvant radiation field. Although a small heterogeneous population was included, this might be due to an inadequate response to neoadjuvant chemoradiotherapy leading to a trend towards worse PFS and OS in ypT0N + patients. Larger studies need to validate our findings. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Mesothelioma and thymic tumors: Treatment challenges in (outside) a network setting
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Martina Imbimbo, Jean-Michel Maury, Marina Garassino, Nicolas Girard, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick Arveux, Marc MaynadiéAbstractThe management of patients with mesothelioma and thymic malignancy requires continuous multidisciplinary expertise at any step of the disease. A dramatic impr...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Editorial Board
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Epidemiology of rare cancers and inequalities in oncologic outcomes
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): G. Gatta, A. Trama, R. Capocaccia, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick Arveux, Marc Maynadié, Anne-Sophie WoronoffAbstractRare cancers epidemiology is better known compared to the other rare diseases. Thanks to the long history of the European population-based cancer registries and to the EUR...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Networking in rare cancers: What was done, what's next
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Anna Maria Frezza, Annalisa Trama, Jean-Yves Blay, Paolo G. CasaliAbstractRare cancers represent approximately one fourth of all cancers. Despite being a heterogeneous group of diseases, they share similar problems including lack of expertise, issues in quality of care, discrepancies in outcome and limitations in research. Traditionally, centralization of rare cancer patients to dedicated reference centres has been recommended to ensure expertise, multidisciplinarity and access to innovation. However, centralization en...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Centers of excellence or excellence networks: The surgical challenge and quality issues in rare cancers
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): S. Sandrucci, P. Naredi, S. BonvalotAbstractThere are several suggestions that centralization of care improves outcome for rare cancers, particularly when optimal treatment requires complex surgery or high-technology radiotherapy equipment. Diagnosis and treatment in reference centers are expected to be more accurate because they benefit from large numbers of cases discussed in a multidisciplinary tumor board with a well-run pathway. However, centralization is sometimes moderately perceived by oncologists as a solution...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Evidence-based data and rare cancers: The need for a new methodological approach in research and investigation
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): S. Mathoulin-Pélissier, K. Pritchard-JonesAbstractRare cancers are not so rare, their incidence is increasing and, as a group, they have worse survival than the common cancers. These factors emphasise the societal need to ensure sufficient focus on research into their biological basis, aetiological factors, new more effective therapies and organisation of healthcare to improve access to best practice and innovation. Accuracy of diagnosis is one of the first hurdles to be overcome, with around one third of tumour...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a network setting: Soft tissue sarcomas
This article will discuss issues with management of patients with STS, such as pathological diagnosis and adherence to guidelines, and the definition of referral centres and networks will be illustrated along with existing experiences and population-based data. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a network setting: Head and neck cancers
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Ester Orlandi, Salvatore Alfieri, Christian Simon, Annalisa Trama, Lisa Licitra, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick ArveuxAbstractHead and neck cancer (HNC) is a rare disease that can affect different sites and is characterized by variable incidence and 5-year survival rates across Europe.Multiple ...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a specialist network setting: Pancreatic neuroendocrine tumours
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Panagis M. Lykoudis, Stefano Partelli, Francesca Muffatti, Martyn Caplin, Massimo Falconi, Giuseppe K. Fusai, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie BouvierAbstractPancreatic Neuroendocrine Neoplasms comprise a group of rare tumours with special biology, an often indolent behaviour and particular diagnostic and therape...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a network setting: Gastrointestinal neuroendocrine tumours
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Faidon-Marios Laskaratos, Martyn CaplinAbstractGastroenteropancreatic neuroendocrine tumours (GEP NETs) are relatively rare neoplasms arising from the enterochromaffin cells of the gastrointestinal tract. They comprise a heterogeneous group of tumours with a diverse natural history, variable biological behaviour and different clinical outcomes. Their management is often complex and may include a combination of surgery, systemic treatments and locoregional approaches. A multidisciplinary team approach is therefore ...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Nicola Nicolai, Davide Biasoni, Mario A. Catanzaro, Maurizio Colecchia, Annalisa Trama, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick ArveuxAbstractGerm-cell tumours (GCT) of the testis and penile squamous cell carcinoma (PeSCC) are a rare and a very rare uro-genital cancers, respectively. Both tumours are we...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Rare ovarian tumours: Epidemiology, treatment challenges in and outside a network setting
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): I. Ray-Coquard, AnnaLisa Trama, M.J. Seckl, C. Fotopoulou, P. Pautier, S. Pignata, G. Kristensen, G. Mangili, H. Falconer, L. Massuger, J. Sehouli, E. Pujade-Lauraine, D. Lorusso, F. Amant, E. Rokkones, I. Vergote, J.A. Ledermann, Monika Hackl, Elizabeth Van Eycken, Kris HenauAbstractPurpose of the reviewMore than 50% of all gynaecological cancers can be classified as rare tumours (defined as an annual incidence of
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Calendar
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Announcements
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Silver-coated (Agluna®) tumour prostheses can be a protective factor against infection in high risk failure patients
ConclusionsSilver-coated prostheses in high risk patients show similar infection free survival as non-silver coated prosthesis in standard sites in primary bone tumours of the extremities. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 15, 2018 Category: Surgery Source Type: research

Early local recurrence and one-year mortality of rectal cancer after restricting the neoadjuvant therapy regime
Publication date: Available online 12 December 2018Source: European Journal of Surgical OncologyAuthor(s): Janneke J.C. Tersteeg, Levi M. van Esch, Paul D. Gobardhan, Peter A.M. Kint, Tom Rozema, Rogier M.P.H. Crolla, Jennifer M.J. SchreinemakersAbstractIntroductionTo reduce the risk of local recurrence after rectal cancer surgery, neoadjuvant radiotherapy (RT) can be applied. However, as this causes morbidity and increases mortality, new Dutch guidelines withhold RT in low-risk patients. The aim of this study is to investigate if early local recurrence and one-year mortality in rectal cancer patients has changed since thi...
Source: European Journal of Surgical Oncology (EJSO) - December 13, 2018 Category: Surgery Source Type: research

Oncologic outcomes of minimally invasive versus open distal pancreatectomy for pancreatic ductal adenocarcinoma: A systematic review and meta-analysis
Publication date: Available online 13 December 2018Source: European Journal of Surgical OncologyAuthor(s): Jony van Hilst, Maarten Korrel, Thijs de Rooij, Sanne Lof, Olivier R. Busch, Bas Groot Koerkamp, David A. Kooby, Susan van Dieren, Mo Abu Hilal, Marc G. Besselink, DIPLOMA study groupAbstractIn the absence of randomized trials, uncertainty regarding the oncologic efficacy of minimally invasive distal pancreatectomy (MIDP) remains. This systematic review aimed to compare oncologic outcomes after MIDP (laparoscopic or robot-assisted) and open distal pancreatectomy (ODP) in patients with pancreatic ductal adenocarcinoma ...
Source: European Journal of Surgical Oncology (EJSO) - December 13, 2018 Category: Surgery Source Type: research

High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis
Publication date: Available online 11 December 2018Source: European Journal of Surgical OncologyAuthor(s): Nerys Dawn Forester, Simon Lowes, Elizabeth Mitchell, Maureen TwiddyAbstractIntroductionProvide evidence to support evolving management strategies for high-risk (B3) breast lesions by assessing risk of carcinoma in subgroups of B3 lesions using systematic review and meta-analysis.MethodsDatabases identified observational studies between 1980 and 2015 that reported on underestimation of malignancy following B3 lesion diagnosis at core needle biopsy. Critical appraisal, quality assessment, data extraction and meta-analy...
Source: European Journal of Surgical Oncology (EJSO) - December 11, 2018 Category: Surgery Source Type: research

Rates of lymph node invasion and their impact on cancer specific mortality in upper urinary tract urothelial carcinoma
Publication date: Available online 11 December 2018Source: European Journal of Surgical OncologyAuthor(s): Sebastiano Nazzani, Elio Mazzone, Felix Preisser, Zhe Tian, Francesco A. Mistretta, Shahrokh F. Shariat, Emanuele Montanari, Pietro Acquati, Alberto Briganti, Fred Saad, Luca Carmignani, Pierre I. KarakiewiczAbstractPurposeTo analyze lymph node invasion (LNI) rates according to tumor characteristics and to test the impact of LNI and its extent on cancer specific mortality (CSM) in surgically-treated non metastatic urothelial upper urinary tract carcinoma (UTUC) patients.Materials and methodsWithin the SEER database (2...
Source: European Journal of Surgical Oncology (EJSO) - December 11, 2018 Category: Surgery Source Type: research

The liver-first approach for locally advanced rectal cancer and synchronous liver metastases
ConclusionTen patients had a (near) complete response of their primary tumour and, in retrospect, rectum sparing therapies could have been considered. Together with 36 patient in whom palliative rectum resection was not necessary this entails that nearly 40% patients with LARC and sRLM might be spared major pelvic surgery if the liver-first approach is applied. A predictor (CEA) was found for non-completion of the liver-first protocol. The majority of patients underwent resection of both primary tumour and hepatic metastasis with curative intent. These findings together entail that the liver-first approach may be considere...
Source: European Journal of Surgical Oncology (EJSO) - December 10, 2018 Category: Surgery Source Type: research

Off-clamp vs on-clamp robotic partial nephrectomy: Perioperative, functional and oncological outcomes from a propensity-score matching between two high-volume centers
ConclusionWe confirm no significant differences in the perioperative and oncological outcomes between off-clamp and on-clamp RPN. Avoided ischemia benefits renal function within 1-year follow-up after surgery. At longer follow-up, difference with on-clamp is softened. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 9, 2018 Category: Surgery Source Type: research

Long-term outcomes following minimally invasive and open esophagectomy in Finland: A population-based study
ConclusionsIn this population-based propensity matched study, minimally invasive esophagectomy was associated with improved long-term survival. Due to multiple confounding factors replication studies are needed. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 7, 2018 Category: Surgery Source Type: research

Changing outlook for colorectal liver metastasis resection in the elderly
This study sought to evaluate the impact of the advancements in clinical care, obtained over the last 20 years, for patients aged 70 and older undergoing liver resection for colorectal liver metastases (CRLM).MethodsConsecutive patients age 70 or older who underwent liver resection for CRLM at Aintree University Hospital (Liverpool, UK) between May 2008 and May 2015 were compared to a dataset of consecutive patients, meeting the same criteria, between 1990 and 2007. An enhanced recovery programme after surgery (ERAS) combined with cardiopulmonary exercise testing (CPET) was introduced in January 2008.ResultsThe proportion ...
Source: European Journal of Surgical Oncology (EJSO) - December 5, 2018 Category: Surgery Source Type: research

Minimally invasive McKeown's vs open oesophagectomy for cancer: A meta-analysis
ConclusionsMcKeown’s-MIO is a safe and effective procedure that has comparable outcomes to OO. However, RCTs with large sample sizes are needed to confirm these results. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 3, 2018 Category: Surgery Source Type: research

Can sentinel node biopsy be safely omitted in thin melanoma? Risk factor analysis of 1272 multicenter prospective cases
Publication date: Available online 1 December 2018Source: European Journal of Surgical OncologyAuthor(s): Dario Piazzalunga, Marco Ceresoli, Niccolò Allievi, Simone Ribero, Pietro Quaglino, Sara Di Lorenzo, Bartolo Corradino, Luca Giovanni Campana, Simone Mocellin, Carlo Riccardo Rossi, IMI (Italian Melanoma Intergroup)AbstractBackgroundThe indication to sentinel node biopsy (SNB) for thin melanomas (Breslow
Source: European Journal of Surgical Oncology (EJSO) - December 2, 2018 Category: Surgery Source Type: research

Electrochemotherapy – Emerging applications technical advances, new indications, combined approaches, and multi-institutional collaboration
Publication date: Available online 1 December 2018Source: European Journal of Surgical OncologyAuthor(s): Luca G. Campana, Ibrahim Edhemovic, Declan Soden, Anna M. Perrone, Marco Scarpa, Laura Campanacci, Maja Cemazar, Sara Valpione, Damijan Miklavčič, Simone Mocellin, Elisabetta Sieni, Gregor SersaAbstractThe treatment of tumors with electrochemotherapy (ECT) has surged over the past decade. Thanks to the transient cell membrane permeabilization induced by the short electric pulses used by ECT, cancer cells are exposed to otherwise poorly permeant chemotherapy agents, with consequent increased cytotoxicity. The codifica...
Source: European Journal of Surgical Oncology (EJSO) - December 2, 2018 Category: Surgery Source Type: research

Central pancreatectomy for benign or low-grade malignant pancreatic lesions - A single-center retrospective analysis of 116 cases
ConclusionsCP is associated with high rates of abdominal complications, however, considering the amount of the normal pancreas that was spared, it might be indicated for selected benign or low-malignancy pancreatic tumors. CP patients have the same incidence of diabetes than the general population. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 30, 2018 Category: Surgery Source Type: research

Diffusion-weighted imaging and loco-regional N staging of patients with colorectal liver metastases
Publication date: Available online 28 November 2018Source: European Journal of Surgical OncologyAuthor(s): Bonifacio Cristiana, Viganò Luca, Felisaz Paolo, Lopci Egesta, Cimino Matteo, Poretti Dario, Donadon Matteo, Pedicini Vittorio, Procopio Fabio, Chiti Arturo, Balzarini Luca, Torzilli GuidoAbstractIntroductionDiffusion-weighted MRI (DWI) contributes to N staging of rectal cancers and diagnosis of colorectal liver metastases (CLM). About 15% of CLM patients have loco-regional lymph node (LN) metastases that impact prognosis and treatment strategy. This retrospective study is the first one to evaluate quantitative...
Source: European Journal of Surgical Oncology (EJSO) - November 29, 2018 Category: Surgery Source Type: research

Minimally invasive McKeown's vs open oesophagectomy for cancer: A meta-analysis
ConclusionsMcKeown’s-MIO is a safe and effective procedure that has comparable outcomes to OO. However, RCTs with large sample sizes are needed to confirm these results. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 25, 2018 Category: Surgery Source Type: research

Response assessment after (chemo)radiotherapy for rectal cancer: Why are we missing complete responses with MRI and endoscopy?
ConclusionsOverstaging of residual tumour after (chemo)radiotherapyin rectal cancer is mainly due to residual mucosal abnormalities at endoscopy, mixed signal intensity or irregular fibrosis at T2-MRI, diffusion restriction at DWI and residual suspicious lymph nodes. Presence of these features is not definitely associated with residual tumour and in selected cases an extended waiting interval can be considered. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 25, 2018 Category: Surgery Source Type: research

Tweeting the meeting: Quantitative and qualitative twitter activity during the 38th ESSO conference
ConclusionsActivity on tweeter during the conference was considerable, with a potential for a wide reach beyond those attending the conference. A more structured approach to the use of twitter for future conferences may enhance experience, activity and reach. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 24, 2018 Category: Surgery Source Type: research

ypT0N+ status in oesophageal cancer patients: Location of residual metastatic lymph nodes with regards to the neoadjuvant radiation field
ConclusionMost ypT0N + lymph nodes are located within the neoadjuvant radiation field. Although a small heterogeneous population was included, this might be due to an inadequate response to neoadjuvant chemoradiotherapy leading to a trend towards worse PFS and OS in ypT0N + patients. Larger studies need to validate our findings. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Resection of small bowel adenocarcinoma metastases: Results of the ARCAD-NADEGE cohort study
ConclusionOverall survival of patients after resection of metastatic SBA remains poor, but long-term survivors are observed. Resection of metastatic SBA should be consider if patients are expected to be operated on with curative intent and have moderately or well-differentiated tumors. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Surgical outcomes of gastrectomy with D1 lymph node dissection performed for patients with unfavorable clinical conditions
Publication date: Available online 22 November 2018Source: European Journal of Surgical OncologyAuthor(s): Marcus Fernando Kodama Pertille Ramos, Marina Alessandra Pereira, Andre Roncon Dias, Osmar Kenji Yagi, Evelise Pelegrinelli Zaidan, Ulysses Ribeiro-Júnior, Bruno Zilberstein, Ivan CecconelloAbstractBackgroundGastric cancer (GC) patients with advanced age and/or multiple morbidities have limited expected survival and may not benefit from extended lymph node resection. The aim of this study was to evaluate the surgical outcomes of these GC patients who underwent gastrectomy with D1 dissection.MethodsWe retrospect...
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Calendar
Publication date: December 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 12Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Editorial Board
Publication date: December 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 12Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Decrease in 30-day and one-year mortality over time in patients aged ≥75 years with stage I–III colon cancer: A population-based study
Publication date: December 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 12Author(s): A.J. Breugom, E. Bastiaannet, J.W.T. Dekker, M.W.J.M. Wouters, C.J.H. van de Velde, G.J. LiefersAbstractBackgroundMonitoring time trends of cancer mortality is essential. Thirty-day mortality is an important surgical outcome measure, though postoperative mortality exceeds to one year after surgery in patients with colorectal cancer. The aim of this nationwide observational study was to assess changes over time in 30-day and one-year mortality in patients with stage I–III colorectal cancer.MethodsAll surgically ...
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Impact of HPV-associated p16-expression and other clinical factors on therapeutic decision-making in patients with oropharyngeal cancer: A GETTEC multicentric study
Publication date: December 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 12Author(s): Dorian Culié, Renaud Garrel, Julien Viotti, Renaud Schiappa, Emmanuel Chamorey, Nicolas Fakhry, Benjamin Lallemant, Sébastien Vergez, Agnès Dupret-Bories, Olivier Dassonville, Gilles Poissonnet, José Santini, Frédéric Peyrade, Karen Benezery, Anne Sudaka, Florence Jourdan-Soulier, Françoise Chapel, Bruno Guelfucci, Alexandre BozecAbstractObjectivesTo analyze the impact of tumor p16 status and other clinical factors on the therapeutic decision-making process in patients...
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Erratum to “2180. Prognostic factors for surgical outcome and survival in women treated for borderline ovarian tumors.” [Eur J Surg Oncol 44 (2018) 1835]
Publication date: December 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 12Author(s): Medhat Esam Eldin Helmy, Gamal Amira, Amany Abd-Elhameed Abou-Bakr, Nabih Elsebaey Elkhouly, Haitham Aboali Hamza, Mohamed Zakaria Sayer Dayer (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Announcements
Publication date: December 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 12Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 22, 2018 Category: Surgery Source Type: research

Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage II/III): The analysis of data from the clinical trial (JCOG0212)
ConclusionsPatient age, tumor location, and short-axis diameter of lateral pelvic lymph node were predictive factors of pathological lateral pelvic lymph node metastasis. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - November 21, 2018 Category: Surgery Source Type: research