Differences in cutaneous melanoma outcomes with changes in lymphoscintigraphy timings?
Publication date: Available online 10 March 2019Source: European Journal of Surgical OncologyAuthor(s): Torin H.A. Elmhirst, Amer J. Durrani, Animesh J.K. Patel (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 11, 2019 Category: Surgery Source Type: research

Sub-millimeter surgical margin is acceptable in patients with good tumor biology after liver resection for colorectal liver metastases
ConclusionsTumor biology plays an important role in deciding the appropriate resection margin in patients with CRLM undergoing radical surgery. R1 resection margin is only acceptable in RAS wild-type patients who respond to chemotherapy. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 11, 2019 Category: Surgery Source Type: research

Corrigendum to “A retrospective study on parasitic thyroid nodules: A Romanian single-center 20-years experience” [45 (2) (February 2019) e124]
Publication date: Available online 9 March 2019Source: European Journal of Surgical OncologyAuthor(s): E.A. Bonci, A. Petrusan, V.I. Bobes, S. Titu, E. Puscas, C. Lisencu, A. Irimie, P. Achimas-Cadariu, D. Piciu, B. Fetica (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 9, 2019 Category: Surgery Source Type: research

Pathological complete response may underestimate distant metastasis in locally advanced rectal cancer following neoadjuvant chemoradiotherapy and radical surgery: Incidence, metastatic pattern, and risk factors
Publication date: Available online 9 March 2019Source: European Journal of Surgical OncologyAuthor(s): Yanwu Sun, Xuejing Wu, Yiyi Zhang, Huiming Lin, Xingrong Lu, Ying Huang, Pan ChiAbstractAimTo evaluate the pattern of tumor relapse of pathological complete response (pCR) patients with locally advanced rectal cancer (LARC) following neoadjuvant chemoradiotherapy (nCRT) and total mesorectal excision (TME), and to identify predictive factors of distant metastasis in pCR patients after nCRT.MethodThis was a retrospective analysis of 118 LARC patients who achieved a pCR following nCRT and TME from 2008 to 2015. Clinicopathol...
Source: European Journal of Surgical Oncology (EJSO) - March 9, 2019 Category: Surgery Source Type: research

Downstaging of lymph node metastasis after neoadjuvant intraperitoneal and systemic chemotherapy in gastric carcinoma with peritoneal metastasis
ConclusionDownstaging of LNMs were achieved in patients of gastric cancer with PM who received NIPS. Downstaging of LNMs after NIPS is related with the prognosis of gastric cancer and should be valued in subsequent surgery for gastric cancer with peritoneal and lymph nodes metastasis. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 9, 2019 Category: Surgery Source Type: research

Impact of body mass index on tumor recurrence among patients undergoing curative-intent resection of intrahepatic cholangiocarcinoma- a multi-institutional international analysis
ConclusionIncreasing BMI was associated with incremental increases in the risk of recurrence following curative-intent resection of ICC. Future studies should aim to achieve a better understanding of BMI-related factors relative to prognosis of patients with ICC. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 9, 2019 Category: Surgery Source Type: research

Corrigendum to ‘Surgery in perforated pediatric intestinal lymphoma’ [European Journal of Surgical Oncology 45 (2019) 279–283]
Publication date: Available online 7 March 2019Source: European Journal of Surgical OncologyAuthor(s): Gehad Ahmed, Maged ElShafiey, Hany Abdelrahman, Samah Semary, Naglaa Elkinaai, Marwa Romeih, Rana Mohy, Alaa Younes (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 9, 2019 Category: Surgery Source Type: research

Reply letter to: Spatial resolution of CT (predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis [clinical stage II/III]: The analysis of data from the clinical trial [JCOG0212])
Publication date: Available online 8 March 2019Source: European Journal of Surgical OncologyAuthor(s): Koji Komori, Shin Fujita (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 9, 2019 Category: Surgery Source Type: research

Surgery and adjuvant radiotherapy for unilateral ductal carcinoma in situ (DCIS) in women aged over 70 years: A population based cohort study
ConclusionTreatment decisions for women with DCIS varied by age at diagnosis. Lower rates of surgery and adjuvant radiotherapy in older women were only partly explained by patient fitness. Better evidence is needed to aid treatment selection for older women with DCIS. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 8, 2019 Category: Surgery Source Type: research

The prognostic value of sarcopenia in patients with surgically treated urothelial carcinoma: A systematic review and meta-analysis
Publication date: Available online 7 March 2019Source: European Journal of Surgical OncologyAuthor(s): Xu Hu, Wei-Chao Dou, Yan-Xiang Shao, Jian-Bang Liu, San-Chao Xiong, Wei-Xiao Yang, Xiang LiAbstractObjectiveSarcopenia is associated with unfavorable prognosis in patients undergoing surgical treatments of the respiratory tract, gastrointestinal tract and urinary tracts. We summarized all available evidence to investigate the prognostic value of sarcopenia in patients with surgically treated urothelial carcinoma (UC).MethodsWe conducted a comprehensive study search up to January 2019, searching the online database Embase,...
Source: European Journal of Surgical Oncology (EJSO) - March 8, 2019 Category: Surgery Source Type: research

Spontaneous rupture of hepatocellular carcinoma: Optimal timing of partial hepatectomy
Publication date: Available online 5 March 2019Source: European Journal of Surgical OncologyAuthor(s): Jing-jing Wu, Peng Zhu, Zhan-guo Zhang, Bi-xiang Zhang, Chang Shu, Abdoul-aziz Mba'nbo-koumpa, Zhi-wei Zhang, Zhi-yong Huang, Wan-guang Zhang, Wan Yee Lau, Xiao-ping ChenAbstractBackgroundPartial hepatectomy has been used to treat patients with resectable hepatocellular carcinoma (HCC) which spontaneously ruptured. It is still controversial as to whether emergency partial hepatectomy (EmPH) should be carried out at the time of rupture, or the patients should initially be managed by operative or non-operative treatment to ...
Source: European Journal of Surgical Oncology (EJSO) - March 6, 2019 Category: Surgery Source Type: research

Post-operative wall shear stress in the superior mesenteric artery: Biomarker of long term outcome in patients with residual disease after incomplete cytoreductive surgery for pseudomyxoma peritonei
The objective was to assess the efficacy of wall shear stress (WSS) measured in superior mesenteric artery (SMA) to predict PMP progression in the postoperative setting to propose additional treatments.MethodsIn a prospective study, 52 patients with PMP had Doppler-ultrasound examination of the SMA with WSS calculation within one year after CRS with a mean follow-up of 43.3 ± 18.3 months. Patients were categorized according to the completeness of CRS and clinical outcome: Group-1 (n = 19): complete CRS and no recurrence, group-2 (n = 20): incomplete CRS with slowly progressive disease (alive at 2 years w...
Source: European Journal of Surgical Oncology (EJSO) - March 6, 2019 Category: Surgery Source Type: research

Ovarian function after ovarian transposition and additional pelvic radiotherapy: A systematic review
ConclusionFrom our systematic review of literature we conclude that the preservation of ovarian function after OT prior to EBRT is successful in 20–100% of patients. Most favorable outcome with regard to preservation of ovarian function is seen in patients after OT and BT, followed by OT and EBRT and OT and RT combined with chemotherapy. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 6, 2019 Category: Surgery Source Type: research

Staging of oropharyngeal squamous cell carcinoma of the head and neck: Prognostic features and power of the 8th edition of the UICC staging manual
Conclusion8th edition of UICC achieves to differentiate properly between the UICC stages. However, the staging rule of ignoring ENE in HPV-mediated OPSCC should be further analyzed. Moreover LNR might be a possible additional prognostic factor – especially regarding HPV-positive tumors. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - March 4, 2019 Category: Surgery Source Type: research

Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer
Publication date: Available online 27 February 2019Source: European Journal of Surgical OncologyAuthor(s): Stephen T. McSorley, Alexander Tham, Colin W. Steele, Ross D. Dolan, Campbell SD. Roxburgh, Paul G. Horgan, Donald C. McMillanAbstractBackgroundInflammation is recognised to be associated with perturbation of serum measures of iron status. However, the impact of colorectal cancer associated host inflammation on red cell measures of iron status has not been previously quantified.MethodsPatients undergoing elective surgery with curative intent, for colorectal cancer, at a single centre between 2008 and 2017 were include...
Source: European Journal of Surgical Oncology (EJSO) - February 28, 2019 Category: Surgery Source Type: research

Peritoneal MRI in patients undergoing cytoreductive surgery and HIPEC: History, clinical applications, and implementation
Publication date: Available online 28 February 2019Source: European Journal of Surgical OncologyAuthor(s): Russell N. Low, Robert M. Barone, Pascal RoussetAbstractMR imaging provides considerable advantages in the evaluation of patients with peritoneal metastases. A standardized peritoneal MRI protocol, including diffusion-weighted and gadolinium-enhanced sequences, allows an efficient exploration of small peritoneal tumors that are often missed on other imaging tests. In experienced hands, a dedicated reading allows producing a quantitative and qualitative evaluation of lesional localization to better assist surgeons in t...
Source: European Journal of Surgical Oncology (EJSO) - February 28, 2019 Category: Surgery Source Type: research

Evaluation of the efficacy and toxicity of upper extremity isolated limb infusion chemotherapy for melanoma: An Australian multi-center study
ConclusionsUL-ILI is safe to perform and effective, resulting in low limb toxicity. CR rates were similar to those for LL-ILI, but OR rates were lower for UL-ILI. It may be possible to improve OR rates achieved by UL-ILI by optimizing perioperative factors while maintaining low toxicity. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 27, 2019 Category: Surgery Source Type: research

UQCRC1 downregulation is correlated with lymph node metastasis and poor prognosis in CRC
Publication date: Available online 26 February 2019Source: European Journal of Surgical OncologyAuthor(s): W. Li, G. Wubulikasimu, X. Zhao, C. Wang, R. Liu, L. Wang, X. Zhu, Z. ChenAbstractBackgroundMitochondrial dysfunction is common in cancer. UQCRC1 is a nuclear-encoded protein localized to the inner mitochondrial membrane; however, little is known about it in colorectal cancer (CRC). The purpose of this study was to investigate the expression pattern and the possible clinical significance of UQCRC1 in CRC.MethodsA total of 197 patients with CRC were enrolled in this study. Immunohistochemistry was used to evaluate the ...
Source: European Journal of Surgical Oncology (EJSO) - February 26, 2019 Category: Surgery Source Type: research

A comparison of outcomes following total and selective peritonectomy performed at the time of interval cytoreductive surgery for advanced serous epithelial ovarian, fallopian tube and primary peritoneal cancer – A study by INDEPSO
ConclusionsTPP was not associated with increased morbidity compared to SPP. There was a trend towards a longer OS in the TPP group and the finding of residual disease in ‘normal looking’ peritoneum’ warrants prospective evaluation of the benefit of TPP in this setting. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 25, 2019 Category: Surgery Source Type: research

Radical cystectomy under continuous antiplatelet therapy with acetylsalicylic acid
ConclusionPerioperative continuation of therapy with acetylsalicylic acid in radical cystectomy is safe with no difference in intraoperative blood loss, transfusion rate, complications or mortality. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 23, 2019 Category: Surgery Source Type: research

Autopsy of an expert consensus: End of hyperthermic intraperitoneal chemotherapy in colorectal carcinomatosis. Editorial
Publication date: Available online 23 February 2019Source: European Journal of Surgical OncologyAuthor(s): Alberto Gómez Portilla (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 23, 2019 Category: Surgery Source Type: research

Individual prediction of lateral neck metastasis risk in patients with unifocal papillary thyroid carcinoma
ConclusionTwo predictive nomograms were generated. Nomogram (c) is a clinical model, whereas nomogram (c + p) is a clinicopathological model. Each nomogram incorporates only four variables and can give an accurate estimate of LNM risk in unifocal PTC patients, which may assist clinicians in patient counseling and decision making regarding LND. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 22, 2019 Category: Surgery Source Type: research

Is bile leakage after hepatic resection associated with impaired long-term survival?
ConclusionsMany concerns have been raised regarding tumour progression after major complications. In this study, we only found a relevant influence of BL on OS in pCC, whereas no association was seen in other cancer types, indicating that tumour progression might be triggered by BL in cancer types arising from the bile ducts itself. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 22, 2019 Category: Surgery Source Type: research

Multicentre validation of a clinical prognostic score integrating the systemic inflammatory response to the host for patients treated with curative-intent for colorectal liver metastases: The Liverpool score
This study aimed to create a new prognostic score integrating the systemic inflammatory response to predict survival in patients treated with curative intent for colorectal liver metastases (CLM).MethodsWe identified independent prognostic factors in patients who underwent liver surgery for CLM in a tertiary centre in the United Kingdom (UK) between 2010 and 2015. A pre- and a postoperative score (Liverpool score) were created by combining these factors to stratify patients into different risk groups. These new scores were validated in an international cohort of 219 patients from China and France.ResultsMultivariate cox re...
Source: European Journal of Surgical Oncology (EJSO) - February 22, 2019 Category: Surgery Source Type: research

Invited editorial re: “Response assessment after (chemo) radiotherapy for rectal cancer: Why are we missing complete responses with MRI and endoscopy?”
Publication date: Available online 20 February 2019Source: European Journal of Surgical OncologyAuthor(s): Deborah S. Keller, Gina Brown (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 20, 2019 Category: Surgery Source Type: research

2019 Calendar
Publication date: March 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 3Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 20, 2019 Category: Surgery Source Type: research

Editorial Board
Publication date: March 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 3Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 20, 2019 Category: Surgery Source Type: research

Thyroidectomy for thyroid cancer in the elderly: A meta-analysis
Publication date: March 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 3Author(s): Kyle R. Joseph, Senarath Edirimanne, Guy D. EslickAbstractThyroid cancer, the most common endocrine malignancy, has patients who generally have excellent prognosis. It has been shown that elderly patients are more likely to undergo sub-therapeutic management, despite having more aggressive disease, resulting in increased mortality and morbidity. The present study aimed to quantitatively investigate the risks of elderly patients who underwent thyroidectomy for thyroid cancer regarding mortality/survival, recurrence of dis...
Source: European Journal of Surgical Oncology (EJSO) - February 20, 2019 Category: Surgery Source Type: research

Announcements: Training Fellowships
Publication date: March 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 3Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 20, 2019 Category: Surgery Source Type: research

Lymphadenectomy in elderly patients with high-intermediate-risk, high-risk or advanced endometrial cancer: Time to move from personalized cancer medicine to personalized patient medicine!
We examined the survival of elderly women diagnosed with high-risk EC according to whether lymphadenectomy was performed or not.MethodsWe selected women over 70 years with high-intermediate risk, high-risk or advanced EC from a multicenter retrospective cohort of women diagnosed between 2001 and 2013. Multivariate logistic regression models and Cox proportional hazards survival methods for overall survival (OS), disease-free survival (DFS) and cancer-specific survival (CSS) were used for analyses.Results71 women had lymphadenectomy and were compared with the 213 who did not. Recurrence was similar in both groups (42% vs 33...
Source: European Journal of Surgical Oncology (EJSO) - February 19, 2019 Category: Surgery Source Type: research

Predictors for pathological parametrial invasion in clinical stage IIB cervical cancer
ConclusionIn clinical stage IIB cervical cancer, accuracy for pathological parametrial invasion is low-modest. With absence of DSI, only one in five clinical stage IIB diseases has pathological stage IIB disease. Survival of pathological stage IIB varies widely and is largely dependent on nodal factors. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 19, 2019 Category: Surgery Source Type: research

Metastatic pattern discriminates survival benefit of primary surgery for de novo stage IV breast cancer: A real-world observational study
Publication date: Available online 19 February 2019Source: European Journal of Surgical OncologyAuthor(s): Kang Wang, Yang Shi, Zhu-Yue Li, Ye-Lei Xiao, Jie Li, Xiang Zhang, Hong-Yuan LiAbstractIntroductionRole of surgery in the management of de novo stage IV breast cancer (BC) remains controversial. We aimed to determine the survival benefit of primary surgery on the basis of metastatic pattern.Materials and methodsA retrospective cohort study based on the SEER database was conducted to identify patients with de novo stage IV BC diagnosed between 2010 and 2015. Patients were divided into surgery and non-surgery group, and...
Source: European Journal of Surgical Oncology (EJSO) - February 19, 2019 Category: Surgery Source Type: research

Prognostic impact of celiac lymph node involvement in patients after frontline treatment for advanced ovarian cancer
ConclusionCLN involvement and high preoperative tumor burden are independently associated with decreased survival after complete cytoreduction for OC. CLN involvement is a marker of diffuse disease and an independent risk factor for early recurrent disease. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 19, 2019 Category: Surgery Source Type: research

Reply to: Letter re: Efficacy of isolated limb perfusion (ILP) in patients with Merkel cell carcinoma: A multicenter experience
Publication date: Available online 16 February 2019Source: European Journal of Surgical OncologyAuthor(s): Linde M. van Veenendaal, Max F. Madu, Margot E.T. Tesselaar, Cornelis Kees Verhoef, Dirk J. Grünhagen, Alexander C.J. van Akkooi (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 18, 2019 Category: Surgery Source Type: research

Association between the novel classification of lung adenocarcinoma subtypes and EGFR/KRAS mutation status: A systematic literature review and pooled-data analysis
This study aims to determine the association of EGFR/KRAS mutation status with histological subtypes of lung adenocarcinoma (LAC) based on the IASLC/ATS/ERS classification.MethodsPubmed and Cochrane databases were searched from January 2011 to June 2018 for studies that included patients with LAC who underwent surgical resection were classified according to the new IASLC/ATS/ERS classification. EGFR/KRAS status assessment was requireded. The primary outcome was determined by the odds ratio (OR) of the incidence of mutation status of certain of each histological subtype. The reference group consisted of EGFR/KRAS mutation n...
Source: European Journal of Surgical Oncology (EJSO) - February 16, 2019 Category: Surgery Source Type: research

Considerations on “Impact of ABO-incompatibility on hepatocellular carcinoma recurrence after living donor liver transplantation”
Publication date: Available online 14 February 2019Source: European Journal of Surgical OncologyAuthor(s): Desirée Gianardi, Davide Ghinolfi, Simone Guadagni, Luca Morelli (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 15, 2019 Category: Surgery Source Type: research

Solid predominant subtype in lung adenocarcinoma is related to poor prognosis after surgical resection: A systematic review and meta-analysis
ConclusionsSP subtype is associated with significantly worse OS and DFS in patients with LADC after pulmonary resection. These data provide evidence for the integration of the distinct histological LADC subtyping into prognostic tools and guidelines for adjuvant treatment after complete surgical resection. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 14, 2019 Category: Surgery Source Type: research

Surgical delay may extend the indications for nipple-sparing mastectomy: A multicentric study
ConclusionThis is the largest series of SD with NSM presented so far in the literature. In our experience, SD extends indications for NSM in high-risk women. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 14, 2019 Category: Surgery Source Type: research

Reply to: Considerations on “Impact of ABO-incompatibility on hepatocellular carcinoma recurrence after living donor liver transplantation”
Publication date: Available online 12 February 2019Source: European Journal of Surgical OncologyAuthor(s): Seong Hoon Kim (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 12, 2019 Category: Surgery Source Type: research

A retrospective comparative analysis of risk factors and outcomes in direct-to-implant and two-stages prepectoral breast reconstruction: BMI and radiotherapy as new selection criteria of patients
This study revises a series of 397 patients. We conducted a retrospective comparative analysis of risk factors and outcomes between patients undergoing direct to-implant (DTI) and patients undergoing two-stages expander-assisted (TSE) PBR. Univariate binary logistic regression was performed to investigate the association between the incidence of postoperative and aesthetic complications and several variables.521 breasts were included in the analysis, with an average follow-up of 38 months. 210 patients underwent DTI and 187 TSE PBR. No statistical differences were found between the two populations in term of the characteri...
Source: European Journal of Surgical Oncology (EJSO) - February 11, 2019 Category: Surgery Source Type: research

Resection margins and local recurrences in breast cancer: Comparison between conventional and oncoplastic breast conserving surgery
Publication date: Available online 11 February 2019Source: European Journal of Surgical OncologyAuthor(s): Laura Niinikoski, Marjut H.K. Leidenius, Päivi Vaara, Aleksandar Voynov, Päivi Heikkilä, Johanna Mattson, Tuomo J. MeretojaAbstractBackgroundThis retrospective cohort study aims to compare surgical margins, reoperations and local recurrences after conventional or oncoplastic breast conservation surgery (BCS). Furthermore, we aim to investigate differences between various oncoplastic techniques.Material and methodsWe reviewed 1800 consecutive patients with primary invasive breast cancer (N = 1707) or...
Source: European Journal of Surgical Oncology (EJSO) - February 11, 2019 Category: Surgery Source Type: research

Repeat breast-conserving therapy for ipsilateral breast cancer recurrence: A systematic review
Publication date: Available online 10 February 2019Source: European Journal of Surgical OncologyAuthor(s): Coco J.E.F. Walstra, Robert-Jan Schipper, Ingrid G.M. Poodt, Yvonne E. van Riet, Adri C. Voogd, Maurice J.C. van der Sangen, Grard A.P. NieuwenhuijzenAbstractThe standard of care for patients with an ipsilateral breast tumour recurrence (IBTR) after breast-conserving therapy (BCT) is a salvage mastectomy. However, there is growing interest in the feasibility of repeat BCT for these patients. This systematic review contains the latest insights on BCT options for patients with an IBTR after initial BCT.A PubMed literatu...
Source: European Journal of Surgical Oncology (EJSO) - February 10, 2019 Category: Surgery Source Type: research

Reply to: Central pancreatectomy for benign or low-grade malignant pancreatic lesions - A single-center retrospective analysis of 116 cases
Publication date: Available online 8 February 2019Source: European Journal of Surgical OncologyAuthor(s): Salvatore Paiella, Matteo De Pastena, Roberto Salvia (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 9, 2019 Category: Surgery Source Type: research

Comments on “Central pancreatectomy for benign or low-grade malignant pancreatic lesions - A single-center retrospective analysis of 116 cases”
Publication date: Available online 7 February 2019Source: European Journal of Surgical OncologyAuthor(s): Bingqing Du, Xubao Liu (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 8, 2019 Category: Surgery Source Type: research

Microscopically positive surgical margins and local recurrence in thyroid cancer. A meta-analysis
ConclusionMeta-analysis did not find a statistically significant association between microscopically positive surgical margin and local recurrence in this population. A finding of microscopically positive surgical margin in the absence of other adverse factors is not an indication for adjuvant treatment. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 8, 2019 Category: Surgery Source Type: research

Perioperative immune function and pain control may underlie early hospital readmission and 90 day mortality following lung cancer resection: A prospective cohort study of 932 patients
ConclusionsPostoperative mortality is not simply due to fixed factors; the impacts of age, gender and surgical procedure on postoperative survival are reduced when the postoperative course of recovery is examined. Perioperative immune function, as portrayed by the occurrence of infection and lower lymphocyte count in the immediate perioperative period, and pain control method are strongly associated with 90 day mortality; further studies in these fields are indicated as are studies of psychological factors in recovery.Clinical registration numberISRCTN00061628. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 6, 2019 Category: Surgery Source Type: research

Limbs and trunk soft tissue sarcoma systematic local and remote monitoring by MRI and thoraco-abdomino-pelvic scanner: A single-centre retrospective study
ConclusionLocal MRI seems particularly suitable for monitoring deep tumors. In addition, the systematic monitoring by TAP CT highlighted a limited number of cases of exclusive extrathoracic metastases. The schedule of local and remote monitoring should primarily be adjusted to tumor grade. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 6, 2019 Category: Surgery Source Type: research

Stage-specific disease recurrence and survival in localized and regionally advanced cutaneous melanoma
ConclusionA substantial number of patients developed disease recurrence. Of these patients, a considerably high proportion developed distant metastases which had a great impact on survival. Identifying disease recurrence at its earliest stage is crucial because metastatic melanoma remains incurable for most patients. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 6, 2019 Category: Surgery Source Type: research

Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
We present a primer on epigenetics for surgical oncologists with examples from colorectal cancer, breast cancer, pancreatic cancer and hepatocellular carcinoma. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - February 6, 2019 Category: Surgery Source Type: research

Sarcopenia is an effective prognostic indicator of postoperative outcomes in laparoscopic-assisted gastrectomy
Publication date: Available online 6 February 2019Source: European Journal of Surgical OncologyAuthor(s): Xi-Yi Chen, Bo Li, Bing-Wei Ma, Xian-Zhong Zhang, Wei-Zhe Chen, Lie-Sheng Lu, Xian Shen, Cheng-Le Zhuang, Zhen YuAbstractBackgroundThe association between sarcopenia and postoperative outcomes in patients who undergo laparoscopic-assisted gastrectomy is unclear. We aimed to determine the predictive value of sarcopenia for adverse postoperative outcomes after laparoscopic-assisted gastrectomy for gastric cancer.Materials and methodsWe prospectively collected the clinical data of patients who underwent elective radical l...
Source: European Journal of Surgical Oncology (EJSO) - February 6, 2019 Category: Surgery Source Type: research