Survivals of patients with surgically treated and High-grade pancreatic neuroendocrine carcinomas: A comparative study between two American Joint Committee on Cancer 8th tumor-node-metastasis staging systems
Publication date: Available online 11 January 2019Source: European Journal of Surgical OncologyAuthor(s): Min Yang, Yi Zhang, Lin Zeng, Neng-wen Ke, Chun-lu Tan, Bo-le Tian, Bo Xiang, Xu-bao LiuAbstractBackground and objectiveWe aimed to compare the two new defined tumor-node-metastasis (TNM) systems in the American Joint Committee on Cancer (AJCC) 8th staging manual for overall survival (OS) analysis of G3 pancreatic neuroendocrine carcinomas (p-NECs) that are currently proposed for pancreatic exocrine adenocarcinomas (p-EACs) and G1/G2 pancreatic neuroendocrine tumors (p-NETs), respectively.MethodsThe data of patients wh...
Source: European Journal of Surgical Oncology (EJSO) - January 18, 2019 Category: Surgery Source Type: research

Persistent disparities in breast cancer surgical outcomes among hispanic and African American patients
Publication date: Available online 17 January 2019Source: European Journal of Surgical OncologyAuthor(s): Elbert J. Mets, Fouad K. Chouairi, Kyle S. Gabrick, Tomer Avraham, Michael AlperovichAbstractBackgroundRacial disparities among patients who receive breast mastectomy and reconstruction have not been well characterized.MethodsRecords of patients undergoing breast extirpative and reconstructive surgery at a high-volume university-affiliated hospital over 5 consecutive years were reviewed. Patient demographics, breast cancer profiles, reconstructive modality, and outcomes were compared by race.ResultsA total of 1045 pati...
Source: European Journal of Surgical Oncology (EJSO) - January 18, 2019 Category: Surgery Source Type: research

A single-center study on simple mastectomy versus skin-sparing mastectomy in case of pure ductal carcinoma in situ of the breast
ConclusionsIn our study, the LR rate following mastectomy is low, regardless of the surgical technique used, with an excellent OS at 10 years. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - January 18, 2019 Category: Surgery Source Type: research

Does the subtype of breast cancer affect the diagnostic performance of axillary ultrasound for nodal staging in breast cancer patients?
ConclusionThere was no significant difference in the diagnostic performance of axillary US between the subtypes, except for NPV. This was highest in triple negative subtype and lowest in HER2+ tumors. This can be explained by the difference in prevalence of axillary lymph node metastases in our cohort. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - January 15, 2019 Category: Surgery Source Type: research

Is it possible to predict underestimation in ductal carcinoma in situ of the breast? Yes, using a simple score!
This study aimed to describe the prevalence of upstaging in women with an initial diagnosis of pure DCIS and identify predictive factors of invasion.
MethodsThis is a cross-sectional study including patients with an initial unilateral DCIS diagnosed through needle core or vacuum-assisted biopsy. All patients were submitted to surgical excision. Clinical, radiological and histological variables were retrospectively collected from our medical records.
ResultsA total of 169 biopsies diagnosed with DCIS were included in this study. 53 patients presented upstaging for invasive carcinoma (31.4%). In the univariate analysis t...
Source: European Journal of Surgical Oncology (EJSO) - January 15, 2019 Category: Surgery Source Type: research

Survivals of patients with surgically treated and High‐grade pancreatic neuroendocrine carcinomas: A comparative study between two American Joint Committee on Cancer 8th tumor-node-metastasis staging systems
Publication date: Available online 11 January 2019Source: European Journal of Surgical OncologyAuthor(s): Min Yang, Yi Zhang, Lin Zeng, Neng-wen Ke, Chun-lu Tan, Bo-le Tian, Bo Xiang, Xu-bao LiuAbstractBackground and objectiveWe aimed to compare the two new defined tumor-node-metastasis (TNM) systems in the American Joint Committee on Cancer (AJCC) 8th staging manual for overall survival (OS) analysis of G3 pancreatic neuroendocrine carcinomas (p-NECs) that are currently proposed for pancreatic exocrine adenocarcinomas (p-EACs) and G1/G2 pancreatic neuroendocrine tumors (p-NETs), respectively.MethodsThe data of patients wh...
Source: European Journal of Surgical Oncology (EJSO) - January 12, 2019 Category: Surgery Source Type: research

Onco-reconstructive supermicrosurgery
Publication date: Available online 9 January 2019Source: European Journal of Surgical OncologyAuthor(s): Takumi YamamotoAbstractSupermicrosurgery is sophisticated microsurgical technique, which allows dissection and anastomosis of blood/lymphatic vessels and nerves with external diameter of 0.5 mm or smaller. With increasing attention to quality of life of cancer survivors, less invasive and functionally-better oncological reconstruction using supermicrosurgical techniques is warranted. Unlike conventional free flap reconstruction, supermicrosurgical free flaps can be elevated from anywhere using innominate vessels with ...
Source: European Journal of Surgical Oncology (EJSO) - January 10, 2019 Category: Surgery Source Type: research

Patterns of pathological response to neoadjuvant chemotherapy and its clinical implications in patients undergoing interval cytoreductive surgery for advanced serous epithelial ovarian cancer- A study by the Indian Network for Development of Peritoneal Surface Oncology (INDEPSO)
Publication date: Available online 9 January 2019Source: European Journal of Surgical OncologyAuthor(s): Aditi Bhatt, Snita Sinukumar, Sanket Mehta, Dileep Damodaran, Shabber Zaveri, Praveen Kammer, Suniti Mishra, Loma Parikh, Rohit Ranade, Prasanth Penumadu, Firoz RajanAbstractObjectivesThe goals were to study• The pattern of pathological response to neoadjuvant chemotherapy (NACT) and its clinical implications• The impact of chemotherapy response grade (CRG) on survivalMethodsA retrospective analysis of patients undergoing interval cytoreductive surgery (CRS) between January 2013 to December 2017 was performed....
Source: European Journal of Surgical Oncology (EJSO) - January 10, 2019 Category: Surgery Source Type: research

Conversion due to vascular injury during video-assisted thoracic surgery lobectomy: A multicentre retrospective analysis from the Italian video-assisted thoracic surgery group registry
ConclusionVascular injuries in VATS lobectomies represented a rare complication which could directly affect the postoperative outcomes. The predictive factors for conversion were multifactorial and depended on characteristics of centres and surgeons’ seniority. Minimally invasive VATS lobectomy approaches did not influence the risk of vascular damages. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - January 9, 2019 Category: Surgery Source Type: research

Rectal cancer in old age –is it appropriately managed? Evidence from population-based analysis of routine data across the English national health service
This study sought to examine the use of radical rectal cancer treatments and associated outcomes in relation to age across the English NHS.MethodsPatient, tumour and treatment characteristics for all patients diagnosed with a first primary rectal cancer in England between 1st April 2009 and 31st December 2014 were obtained from the CORECT-R data repository. Descriptive analyses and adjusted logistic regression models were undertaken to examine any association between age and the use of major resection and post-surgical outcomes. Funnel plots were used to show variation in adjusted rates of major resection.ResultsThe propor...
Source: European Journal of Surgical Oncology (EJSO) - January 9, 2019 Category: Surgery Source Type: research

Implementation of value based breast cancer care
ConclusionAssessment of patient reported as well as provider reported outcomes was implemented within our standard of breast cancer care. For this, dedicated resources, change of culture and practice, and improved knowledge and awareness about Value Based Health Care (VBHC) were essential. Our proposed framework aims to serve as a blueprint for implementation of VBHC in daily care. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - January 5, 2019 Category: Surgery Source Type: research

Is the AJCC TNM staging system still appropriate for gastric cancer patients survival after 5 years?
Publication date: Available online 4 January 2019Source: European Journal of Surgical OncologyAuthor(s): Jian-Xian Lin, Jun-Peng Lin, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Chao-Hui Zheng, Chang-Ming Huang, Ping LiAbstractPurposeThe aim of this study was to evaluate the prognostic value of the eighth AJCC TNM staging classification for patients with gastric cancer who had already survived for 5 years.Patients and methodsPatients who underwent radical gastrectomy at a large eastern center were considered. The prognostic value of staging systems were assessed and compared. Additio...
Source: European Journal of Surgical Oncology (EJSO) - January 5, 2019 Category: Surgery Source Type: research

Variability in breast cancer surgery training across Europe: An ESSO-EUSOMA international survey
ConclusionThere is a great variability in breast cancer surgery training in Europe. It is imperative to develop quality standards for breast cancer surgery training to ensure that patients get standardized and certified surgical management regardless of the country in which they are treated. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - January 5, 2019 Category: Surgery Source Type: research

Breast cancer treatment-related lymphedema (BCRL): An overview of the literature and updates in microsurgery reconstructions
Publication date: Available online 4 January 2019Source: European Journal of Surgical OncologyAuthor(s): Bayu Brahma, Takumi YamamotoAbstractBreast cancer is the most common cancer in Dharmais hospital. The treatment can give rise to breast cancer treatment-related lymphedema (BCRL) that will cause significant morbidities. Based on author's (BB) patient series in Dharmais hospital, BCRL occurred in 27.7% after axillary lymph nodes dissection (ALND). The development of diagnostic modalities as well as lymphatic microsurgery have become promising instruments for lymphedema treatment. To date, modern approach of lymphedema ca...
Source: European Journal of Surgical Oncology (EJSO) - January 4, 2019 Category: Surgery Source Type: research

Survival outcomes following adrenalectomy for isolated metastases to the adrenal gland
Publication date: Available online 4 January 2019Source: European Journal of Surgical OncologyAuthor(s): Jason Ramsingh, Patrick O'Dwyer, Carol WatsonAbstractBackgroundAdrenal metastases can arise from different primary sites. Surgical resection of the adrenal gland in patients with isolated metastases may offer improved survival in many of these patients. However, the benefit of surgery in this heterogenous group is often disputed. The aim of this study was to identify patients undergoing adrenalectomy for isolated metastases and to describe survival outcomes based on origin of the primary malignancy.MethodsPatients under...
Source: European Journal of Surgical Oncology (EJSO) - January 4, 2019 Category: Surgery Source Type: research

European validation of the Yonsei Gastric Cancer Prognosis Prediction Model after gastrectomy: Validation with the Netherlands Cancer Registry
This study aimed to validate this model in a European cohort.MethodsAll patients who underwent gastrectomy for gastric cancer were selected from the Netherlands Cancer Registry (2005–2015). Patients with 30-day mortality, co-existing cancer, neoadjuvant therapy, or missing data were excluded. The prediction model included gender, age, resection type, pT-stage, pM-stage, number of retrieved lymph nodes, number of metastatic lymph nodes, and tumor histology. The model was validated and compared to the 7th TNM staging system using calibration plots and the concordance index (c-statistic with 95% confidence interval (CI)...
Source: European Journal of Surgical Oncology (EJSO) - January 3, 2019 Category: Surgery Source Type: research

Patterns of recurrence and prognosis in locally advanced FIGO stage IB2 to IIB cervical cancer: Retrospective multicentre study from the FRANCOGYN group
ConclusionsRecurrence location and time to recurrence differ widely depending on the FIGO stage, LN status and treatment modalities, with potential impact on follow-up modalities and therapeutic approaches. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 30, 2018 Category: Surgery Source Type: research

Surgical resection of neuroendocrine tumor liver metastases as part of multimodal treatment strategies: A propensity score matching analysis
ConclusionAfter minimizing patient selection bias, patients with hepatic resection as integral of multimodal therapy of NELM do not have better overall survival than those receiving non-surgical treatment alone. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 29, 2018 Category: Surgery Source Type: research

Long term survival and perioperative propensity score matched outcomes in diaphragmatic interventions in cytoreductive surgery + intra-peritoneal chemotherapy
ConclusionAfter our three-tiered research strategy, we conclude that despite the marginal increase in short term morbidity; diaphragmatic interventions do not decrease survival in colorectal cancers and diaphragmatic disease in LAMNs maybe an independent prognosticator of disease aggression. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 29, 2018 Category: Surgery Source Type: research

An analysis of the morbidity associated with abdominal wall resection and reconstruction after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC)
ConclusionThis study demonstrates that patients undergoing AWR have a higher incidence of postoperative WD. CST was associated with an increased incidence of Grade III WC and WD. Patients with a higher PSS were more likely to develop midline wound recurrence. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 29, 2018 Category: Surgery Source Type: research

Hospital transfer after a breast cancer diagnosis: A population-based study in the Netherlands of the extent, predictive characteristics and its impact on time to treatment
Publication date: Available online 29 December 2018Source: European Journal of Surgical OncologyAuthor(s): E. Heeg, K. Schreuder, P.E.R. Spronk, J.C. Oosterwijk, P.J. Marang-van de Mheen, S. Siesling, M.T.F.D. Vrancken Peeters, NABON Breast Cancer AuditAbstractPurposePatients may transfer of hospital for clinical reasons but this may delay time to treatment. The purpose of this study is to provide insight in the extent of hospital transfer in breast cancer care; which type of patients transfer and what is the impact on time to treatment.MethodsWe included 41,413 breast cancer patients registered in the Netherlands Cancer R...
Source: European Journal of Surgical Oncology (EJSO) - December 29, 2018 Category: Surgery Source Type: research

Hospital volume and outcome in rectal cancer patients; results of a population-based study in the Netherlands
ConclusionHospital volume was not associated with survival in cT1-3 rectal cancer. In cT4 rectal cancer, treatment in high volume cT4 hospitals was associated with improved survival compared to low volume cT4 hospitals, although this association lost statistical significance after correction for neoadjuvant treatment. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 26, 2018 Category: Surgery Source Type: research

Prognostic and clinical significance of syndecan-1 expression in breast cancer: A systematic review and meta-analysis
Publication date: Available online 25 December 2018Source: European Journal of Surgical OncologyAuthor(s): Weiqiang Qiao, Heyang Liu, Wanying Guo, Peng Li, Miao DengAbstractBackgroundThe prognostic value of syndecan-1 (SDC1, also called CD138) in breast cancer remains controversial. Therefore, we performed a meta-analysis to assess the clinical significance of SDC1 expression in breast cancer.Materials and methodsVarious databases were searched to evaluate possible correlations between SDC1 protein or mRNA expression and prognostic significance in breast cancer. Pooled hazard ratios (HRs) and odds ratios (ORs) with 95% con...
Source: European Journal of Surgical Oncology (EJSO) - December 25, 2018 Category: Surgery Source Type: research

Isolated Langerhans islets: Potential pitfall in solid and pseudopapillary neoplasm resection?
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Adriana Handra-Luca (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Survival comparison in gastric cancer patients between 7th and 8th edition of the AJCC TNM staging system: The first western single center experience
ConclusionRestaging system seems to improve survival rate discrimination in particular comparing stage IIIB and stage IIIC; whereas in stage IIIA this is not so clear.More studies are necessary to confirm these data. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Liver resection is justified for multinodular hepatocellular carcinoma in selected patients with cirrhosis a multicenter analysis of 1,066 patients
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Zhen-Li Li, Jiong-Jie Yu, Jun-Wu Guo, Cheng-Jun Sui, Bing-Hua Dai, Wan-Guang Zhang, Ting-Hao Chen, Chao Li, Wei-Min Gu, Ya-Hao Zhou, Hong Wang, Yao-Ming Zhang, Xian-Hai Mao, Timothy M. Pawlik, Ming-Da Wang, Lei Liang, Han Wu, Wan Yee Lau, Meng-Chao Wu, Feng ShenAbstractBackgroundThe role of liver resection for multinodular (≥3 nodules) hepatocellular carcinoma (HCC) remains unclear, especially among patients with severe underlying liver disease. We sought to evaluate surgical outcomes among patients with cirrhosis ...
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

FDG-avid presacral soft tissue mass in previously treated rectal cancer: Diagnostic outcome and additional value of MRI, including diffusion-weighted imaging
ConclusionsFDG-PET/CT has a poor PPV for locally recurrent rectal cancer in the presacral space. The observation of air in the FDG-avid presacral lesion and additional MRI assessment are diagnostically helpful, without a significant additional value of DWI. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

A new nomogram for recurrence-free survival prediction of gastrointestinal stromal tumors: Comparison with current risk classification methods
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Tao Chen, Lili Xu, Liangying Ye, Haibo Qiu, Yanfeng Hu, Hao Liu, Zhiwei Zhou, Guoxin Li, Jiang YuAbstractBackgroundGastrointestinal stromal tumors (GISTs) focused on a popular factor Ki-67 to enable individualized and precise predictions of the most suitable candidates for imatinib therapy.MethodsWe retrospectively collected clinicopathologic data of the patients diagnosed with GISTs from January 1998 to December 2015 at Southern Medical University Nanfang Hospital as the experiment group. And patients with GISTs at...
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Acute malignant obstruction in patients with peritoneal carcinomatosis: The role of palliative surgery
Publication date: Available online 21 December 2018Source: European Journal of Surgical OncologyAuthor(s): Nadine L. de Boer, Jan A.W. Hagemans, Bob T.A. Schultze, Alexandra R.M. Brandt-Kerkhof, Eva V.E. Madsen, Cornelis Verhoef, Jacobus W.A. BurgerAbstractIntroductionPatients with peritoneal carcinomatosis who do not have curative treatment options often develop acute obstructive symptoms and when conservative management fails, surgical treatment is the remaining option. However, palliative surgery is associated with high morbidity and mortality and the chance of success is unclear. The aim of this study was to evaluate o...
Source: European Journal of Surgical Oncology (EJSO) - December 22, 2018 Category: Surgery Source Type: research

Evaluation of the MDACC clinical classification system for pancreatic cancer patients in an European multicenter cohort
This study intents to evaluate the proposed borderline classification system in a multicenter patient cohort without neoadjuvant treatment.MethodsEvaluation was based on a multicenter database of pancreatic cancer patients undergoing surgery from 2005 to 2016 (n = 1020). Complications were classified based on the Clavien-Dindo classification. χ2-test, Kaplan–Meier estimator and Cox regression hazard model were used for statistical analysis.ResultsMost patients (55.1%) were assigned as type A patients, followed by type C (35.8%) and type B patients (9.1%). Neither the complication rate, nor the mortality rate ...
Source: European Journal of Surgical Oncology (EJSO) - December 20, 2018 Category: Surgery Source Type: research

ypT0N+ status in oesophageal cancer patients: Location of residual metastatic lymph nodes with regard to the neoadjuvant radiation field
ConclusionMost ypT0N + lymph nodes are located within the neoadjuvant radiation field. Although a small heterogeneous population was included, this might be due to an inadequate response to neoadjuvant chemoradiotherapy leading to a trend towards worse PFS and OS in ypT0N + patients. Larger studies need to validate our findings. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Mesothelioma and thymic tumors: Treatment challenges in (outside) a network setting
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Martina Imbimbo, Jean-Michel Maury, Marina Garassino, Nicolas Girard, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick Arveux, Marc MaynadiéAbstractThe management of patients with mesothelioma and thymic malignancy requires continuous multidisciplinary expertise at any step of the disease. A dramatic impr...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Editorial Board
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Epidemiology of rare cancers and inequalities in oncologic outcomes
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): G. Gatta, A. Trama, R. Capocaccia, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick Arveux, Marc Maynadié, Anne-Sophie WoronoffAbstractRare cancers epidemiology is better known compared to the other rare diseases. Thanks to the long history of the European population-based cancer registries and to the EUR...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Networking in rare cancers: What was done, what's next
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Anna Maria Frezza, Annalisa Trama, Jean-Yves Blay, Paolo G. CasaliAbstractRare cancers represent approximately one fourth of all cancers. Despite being a heterogeneous group of diseases, they share similar problems including lack of expertise, issues in quality of care, discrepancies in outcome and limitations in research. Traditionally, centralization of rare cancer patients to dedicated reference centres has been recommended to ensure expertise, multidisciplinarity and access to innovation. However, centralization en...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Centers of excellence or excellence networks: The surgical challenge and quality issues in rare cancers
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): S. Sandrucci, P. Naredi, S. BonvalotAbstractThere are several suggestions that centralization of care improves outcome for rare cancers, particularly when optimal treatment requires complex surgery or high-technology radiotherapy equipment. Diagnosis and treatment in reference centers are expected to be more accurate because they benefit from large numbers of cases discussed in a multidisciplinary tumor board with a well-run pathway. However, centralization is sometimes moderately perceived by oncologists as a solution...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Evidence-based data and rare cancers: The need for a new methodological approach in research and investigation
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): S. Mathoulin-Pélissier, K. Pritchard-JonesAbstractRare cancers are not so rare, their incidence is increasing and, as a group, they have worse survival than the common cancers. These factors emphasise the societal need to ensure sufficient focus on research into their biological basis, aetiological factors, new more effective therapies and organisation of healthcare to improve access to best practice and innovation. Accuracy of diagnosis is one of the first hurdles to be overcome, with around one third of tumour...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a network setting: Soft tissue sarcomas
This article will discuss issues with management of patients with STS, such as pathological diagnosis and adherence to guidelines, and the definition of referral centres and networks will be illustrated along with existing experiences and population-based data. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a network setting: Head and neck cancers
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Ester Orlandi, Salvatore Alfieri, Christian Simon, Annalisa Trama, Lisa Licitra, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick ArveuxAbstractHead and neck cancer (HNC) is a rare disease that can affect different sites and is characterized by variable incidence and 5-year survival rates across Europe.Multiple ...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a specialist network setting: Pancreatic neuroendocrine tumours
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Panagis M. Lykoudis, Stefano Partelli, Francesca Muffatti, Martyn Caplin, Massimo Falconi, Giuseppe K. Fusai, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie BouvierAbstractPancreatic Neuroendocrine Neoplasms comprise a group of rare tumours with special biology, an often indolent behaviour and particular diagnostic and therape...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Treatment challenges in and outside a network setting: Gastrointestinal neuroendocrine tumours
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Faidon-Marios Laskaratos, Martyn CaplinAbstractGastroenteropancreatic neuroendocrine tumours (GEP NETs) are relatively rare neoplasms arising from the enterochromaffin cells of the gastrointestinal tract. They comprise a heterogeneous group of tumours with a diverse natural history, variable biological behaviour and different clinical outcomes. Their management is often complex and may include a combination of surgery, systemic treatments and locoregional approaches. A multidisciplinary team approach is therefore ...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): Nicola Nicolai, Davide Biasoni, Mario A. Catanzaro, Maurizio Colecchia, Annalisa Trama, Monika Hackl, Elizabeth Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit Leinonen, Michel Velten, Xavier Troussard, Veronique Bouvier, Anne-Valérie Guizard, Anne-Marie Bouvier, Patrick ArveuxAbstractGerm-cell tumours (GCT) of the testis and penile squamous cell carcinoma (PeSCC) are a rare and a very rare uro-genital cancers, respectively. Both tumours are we...
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Rare ovarian tumours: Epidemiology, treatment challenges in and outside a network setting
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): I. Ray-Coquard, AnnaLisa Trama, M.J. Seckl, C. Fotopoulou, P. Pautier, S. Pignata, G. Kristensen, G. Mangili, H. Falconer, L. Massuger, J. Sehouli, E. Pujade-Lauraine, D. Lorusso, F. Amant, E. Rokkones, I. Vergote, J.A. Ledermann, Monika Hackl, Elizabeth Van Eycken, Kris HenauAbstractPurpose of the reviewMore than 50% of all gynaecological cancers can be classified as rare tumours (defined as an annual incidence of
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Calendar
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Announcements
Publication date: January 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 1Author(s): (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 19, 2018 Category: Surgery Source Type: research

Silver-coated (Agluna®) tumour prostheses can be a protective factor against infection in high risk failure patients
ConclusionsSilver-coated prostheses in high risk patients show similar infection free survival as non-silver coated prosthesis in standard sites in primary bone tumours of the extremities. (Source: European Journal of Surgical Oncology (EJSO))
Source: European Journal of Surgical Oncology (EJSO) - December 15, 2018 Category: Surgery Source Type: research

Early local recurrence and one-year mortality of rectal cancer after restricting the neoadjuvant therapy regime
Publication date: Available online 12 December 2018Source: European Journal of Surgical OncologyAuthor(s): Janneke J.C. Tersteeg, Levi M. van Esch, Paul D. Gobardhan, Peter A.M. Kint, Tom Rozema, Rogier M.P.H. Crolla, Jennifer M.J. SchreinemakersAbstractIntroductionTo reduce the risk of local recurrence after rectal cancer surgery, neoadjuvant radiotherapy (RT) can be applied. However, as this causes morbidity and increases mortality, new Dutch guidelines withhold RT in low-risk patients. The aim of this study is to investigate if early local recurrence and one-year mortality in rectal cancer patients has changed since thi...
Source: European Journal of Surgical Oncology (EJSO) - December 13, 2018 Category: Surgery Source Type: research

Oncologic outcomes of minimally invasive versus open distal pancreatectomy for pancreatic ductal adenocarcinoma: A systematic review and meta-analysis
Publication date: Available online 13 December 2018Source: European Journal of Surgical OncologyAuthor(s): Jony van Hilst, Maarten Korrel, Thijs de Rooij, Sanne Lof, Olivier R. Busch, Bas Groot Koerkamp, David A. Kooby, Susan van Dieren, Mo Abu Hilal, Marc G. Besselink, DIPLOMA study groupAbstractIn the absence of randomized trials, uncertainty regarding the oncologic efficacy of minimally invasive distal pancreatectomy (MIDP) remains. This systematic review aimed to compare oncologic outcomes after MIDP (laparoscopic or robot-assisted) and open distal pancreatectomy (ODP) in patients with pancreatic ductal adenocarcinoma ...
Source: European Journal of Surgical Oncology (EJSO) - December 13, 2018 Category: Surgery Source Type: research

High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis
Publication date: Available online 11 December 2018Source: European Journal of Surgical OncologyAuthor(s): Nerys Dawn Forester, Simon Lowes, Elizabeth Mitchell, Maureen TwiddyAbstractIntroductionProvide evidence to support evolving management strategies for high-risk (B3) breast lesions by assessing risk of carcinoma in subgroups of B3 lesions using systematic review and meta-analysis.MethodsDatabases identified observational studies between 1980 and 2015 that reported on underestimation of malignancy following B3 lesion diagnosis at core needle biopsy. Critical appraisal, quality assessment, data extraction and meta-analy...
Source: European Journal of Surgical Oncology (EJSO) - December 11, 2018 Category: Surgery Source Type: research

Rates of lymph node invasion and their impact on cancer specific mortality in upper urinary tract urothelial carcinoma
Publication date: Available online 11 December 2018Source: European Journal of Surgical OncologyAuthor(s): Sebastiano Nazzani, Elio Mazzone, Felix Preisser, Zhe Tian, Francesco A. Mistretta, Shahrokh F. Shariat, Emanuele Montanari, Pietro Acquati, Alberto Briganti, Fred Saad, Luca Carmignani, Pierre I. KarakiewiczAbstractPurposeTo analyze lymph node invasion (LNI) rates according to tumor characteristics and to test the impact of LNI and its extent on cancer specific mortality (CSM) in surgically-treated non metastatic urothelial upper urinary tract carcinoma (UTUC) patients.Materials and methodsWithin the SEER database (2...
Source: European Journal of Surgical Oncology (EJSO) - December 11, 2018 Category: Surgery Source Type: research