Neurological manifestations and risk factors associated with poor prognosis in hospitalized children with Omicron variant infection
Conclusion: In this study, 32.8% of hospitalized children suffering from COVID-19 due to the Omicron variant infection experienced neurological manifestations. Baseline albumin and CK-MB levels could accurately predict poor prognosis in this patient population.What is Known:• Neurological injury has been reported in SARS-CoV-2 infection; compared with other strains, the Omicron strain is more likely to cause neurological manifestations in adults.• Neurologic injury in adults such as cerebral hemorrhage and epilepsy has been reported in patients with Omicron variant infection.What is New:• One-third hospitalized child...
Source: European Journal of Pediatrics - March 2, 2024 Category: Pediatrics Source Type: research
Educational programmes for paediatric healthcare professionals in patient- and family-centred care. A scoping review
Conclusion: A large variety of educational programmes in paediatric patient- and family-centred care exist. Educational content mainly focused on communication and relational competencies. Experiential learning including roleplay and simulation was the most used educational strategy.What is Known:• Delivery of patient- and family-centred care improves parental satisfaction of care but requires clinicians have a certain attitude towards involving the child and parents in a healthcare partnership as well as advanced triadic communication skills. Little is known about how this attitude, and m ore broadly, patient- and famil...
Source: European Journal of Pediatrics - March 2, 2024 Category: Pediatrics Source Type: research
Correction to: Erythema nodosum in children: a cohort study from a tertiary pediatric hospital in Italy
(Source: European Journal of Pediatrics)
Source: European Journal of Pediatrics - March 2, 2024 Category: Pediatrics Source Type: research
Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial
Conclusion: The uptake ofL. reuteri NCIMB 30351 leads to a significant reduction in the number of regurgitations, feeding-induced constipations, and diarrhea as well as mean daily numbers of crying and crying duration in infants during the first months of life. Our results suggest thatL. reuteri NCIMB 30351 represents a safe and effective treatment for colic in newborns. Trial registration:ClinicalTrials.gov: NCT04262648.What is Known:• Infantile functional gastrointestinal disorders, such as colic, constipation, diarrhea, and gastroesophageal reflux (regurgitation), often occur in early infancy and, represent one of...
Source: European Journal of Pediatrics - March 1, 2024 Category: Pediatrics Source Type: research
In-person versus electronic screening for social risks among carers of pediatric inpatients: A mixed methods randomized trial
Conclusion: Differences in the disclosure of social risks according to self- versus assisted-completion were small, suggesting that either method could be used. Most carers expressed a preference for self- completion, which is therefore recommended as the ideal mode for such data collection for Australian pediatric inpatient settings. Trial registration: Australia New Zealand Clinical Trial Registry (www.anzctry.org.au; #ACTRN12620001326987; date of registration 8 December 2020).What is Known:• Most evidence on screening of social risks in pediatric inpatient settings is from the USA.• Little is known about disclosure...
Source: European Journal of Pediatrics - March 1, 2024 Category: Pediatrics Source Type: research
Influence of gastric residual assessment in preterm neonates on time to achieve enteral feeding (the GRASS trial) —Multi-centre, assessor-blinded randomised clinical trial
Conclusion: There was no difference in time to attainment of enteral feeds of 100 ml/kg/day in premature infants when gastric residuals were not monitored. In the absence of a clinical benefit to routine monitoring, it may be appropriate to discontinue this practice and only monitor residuals when clinical c oncern of feeding intolerance or gastrointestinal pathology arises in this group of patients.Trial registration: NCT03111329—https://clinicaltrials.gov/. Registered 06/04/2017.What is Known:• Previous randomized trials have shown little benefit to the performance of routine assessment of gastric residuals in p...
Source: European Journal of Pediatrics - March 1, 2024 Category: Pediatrics Source Type: research
Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial
Conclusion: The uptake ofL. reuteri NCIMB 30351 leads to a significant reduction in the number of regurgitations, feeding-induced constipations, and diarrhea as well as mean daily numbers of crying and crying duration in infants during the first months of life. Our results suggest thatL. reuteri NCIMB 30351 represents a safe and effective treatment for colic in newborns. Trial registration:ClinicalTrials.gov: NCT04262648.What is Known:• Infantile functional gastrointestinal disorders, such as colic, constipation, diarrhea, and gastroesophageal reflux (regurgitation), often occur in early infancy and, represent one of...
Source: European Journal of Pediatrics - March 1, 2024 Category: Pediatrics Source Type: research
In-person versus electronic screening for social risks among carers of pediatric inpatients: A mixed methods randomized trial
Conclusion: Differences in the disclosure of social risks according to self- versus assisted-completion were small, suggesting that either method could be used. Most carers expressed a preference for self- completion, which is therefore recommended as the ideal mode for such data collection for Australian pediatric inpatient settings. Trial registration: Australia New Zealand Clinical Trial Registry (www.anzctry.org.au; #ACTRN12620001326987; date of registration 8 December 2020).What is Known:• Most evidence on screening of social risks in pediatric inpatient settings is from the USA.• Little is known about disclosure...
Source: European Journal of Pediatrics - March 1, 2024 Category: Pediatrics Source Type: research
Influence of gastric residual assessment in preterm neonates on time to achieve enteral feeding (the GRASS trial) —Multi-centre, assessor-blinded randomised clinical trial
Conclusion: There was no difference in time to attainment of enteral feeds of 100 ml/kg/day in premature infants when gastric residuals were not monitored. In the absence of a clinical benefit to routine monitoring, it may be appropriate to discontinue this practice and only monitor residuals when clinical c oncern of feeding intolerance or gastrointestinal pathology arises in this group of patients.Trial registration: NCT03111329—https://clinicaltrials.gov/. Registered 06/04/2017.What is Known:• Previous randomized trials have shown little benefit to the performance of routine assessment of gastric residuals in p...
Source: European Journal of Pediatrics - March 1, 2024 Category: Pediatrics Source Type: research
Is adherence to the 24-h movement guidelines associated with greater academic-related outcomes in children and adolescents? A systematic review and meta-analysis
Conclusion: Findings from this systematic review and meta-analysis reveal a small association between adherence to all three recommendations and greater academic achievement in children and adolescents. Nevertheless, it is imperative to underscore the need for more studies to establish robust evidence underpinning this relationship. Trial registration: PROSPERO (CRD42021295403).What is Known:• Regular physical activity, reduced screen time, and optimal sleep duration are independently associated with improved academic-related outcomes in children and adolescents.• The associations between adherence to the 24-h move...
Source: European Journal of Pediatrics - February 28, 2024 Category: Pediatrics Source Type: research
Impact of preterm birth on muscle mass and function: a systematic review and meta-analysis
Conclusion: Overall, this systematic review summarizing the existing literature on the impact of preterm birth on skeletal muscle indicates emerging evidence that individuals born preterm, display alteration in the development of their skeletal muscle mass and function. This work also highlights a clear knowledge gap in understanding the effect of preterm birth on skeletal muscle development.What is Known:• Preterm birth, which occurs at a critical time of skeletal muscle development and maturation, impairs the development of different organs and tissues leading to a higher risk of comorbidities such as cardiovascular di...
Source: European Journal of Pediatrics - February 28, 2024 Category: Pediatrics Source Type: research
Congenital diaphragmatic hernia: automatic lung and liver MRI segmentation with nnU-Net, reproducibility of pyradiomics features, and a machine learning application for the classification of liver herniation
Conclusion: Our results suggest that automatic MRI segmentation is feasible, with good reproducibility of pyradiomics features, and that a ML system for liver herniation prediction offers good reliability. Trial registration:https://clinicaltrials.gov/ct2/show/NCT04609163?term=NCT04609163&draw=2&rank=1; Clinical Trial Identification no. NCT04609163.What is Known:• Magnetic resonance imaging (MRI) is crucial for prenatal congenital diaphragmatic hernia (CDH) assessment. It enables the quantification of the total lung volume and the extent of liver herniation, which are essential for stratifying the ...
Source: European Journal of Pediatrics - February 28, 2024 Category: Pediatrics Source Type: research
Neonatal hemodynamics of recipient twins after fetoscopic selective laser coagulation for twin-to-twin transfusion syndrome: An unicist classification
Conclusion: Four distinct and well-characterized groups of recipients were identified based on their hemodynamics. High blood pressure and heart failure occurred in approximately 20% of the infants and were associated with a time between laser coagulation and birth of less than 2 months.What is Known:• Twin-to-twin transfusion syndrome (TTTS) is characterized by a hemodynamic imbalance that leads to high fetal and neonatal mortality if left untreated. One-third of recipient twins born without prenatal fetoscopic laser coagulation (FSLC) develop a life-threatening cardiac failure.What is New:• Four distinct groups of...
Source: European Journal of Pediatrics - February 28, 2024 Category: Pediatrics Source Type: research
Is adherence to the 24-h movement guidelines associated with greater academic-related outcomes in children and adolescents? A systematic review and meta-analysis
Conclusion: Findings from this systematic review and meta-analysis reveal a small association between adherence to all three recommendations and greater academic achievement in children and adolescents. Nevertheless, it is imperative to underscore the need for more studies to establish robust evidence underpinning this relationship. Trial registration: PROSPERO (CRD42021295403).What is Known:• Regular physical activity, reduced screen time, and optimal sleep duration are independently associated with improved academic-related outcomes in children and adolescents.• The associations between adherence to the 24-h move...
Source: European Journal of Pediatrics - February 28, 2024 Category: Pediatrics Source Type: research
Impact of preterm birth on muscle mass and function: a systematic review and meta-analysis
Conclusion: Overall, this systematic review summarizing the existing literature on the impact of preterm birth on skeletal muscle indicates emerging evidence that individuals born preterm, display alteration in the development of their skeletal muscle mass and function. This work also highlights a clear knowledge gap in understanding the effect of preterm birth on skeletal muscle development.What is Known:• Preterm birth, which occurs at a critical time of skeletal muscle development and maturation, impairs the development of different organs and tissues leading to a higher risk of comorbidities such as cardiovascular di...
Source: European Journal of Pediatrics - February 28, 2024 Category: Pediatrics Source Type: research
