Correction to: Exceeding two hours sedentary time is not associated with moderate to severe spinal pain in 11 to 13-year-olds: a cross-sectional analysis
(Source: European Journal of Pediatrics)
Source: European Journal of Pediatrics - January 26, 2024 Category: Pediatrics Source Type: research

Comparison of refugee patients with cystic fibrosis and their counterpart children from Turkey during the war
Conclusion: Although refugee CF patients have equal access to NBS programs and CF medications as well as Turkish patients, the median age at diagnosis of patients, the median age of diagnosis of patients through NBS, their nutritional status, and Pseudomonas colonization were significantly worse than Turkish patients, which may be related to the difficulties of living in another country and poor living conditions. The high genetic heterogeneity and rare mutations detected in the refugee patient group compared to Turkish patients. Well-programmed NBS programs, thorough genetic studies, and the enhancement of living conditio...
Source: European Journal of Pediatrics - January 24, 2024 Category: Pediatrics Source Type: research

Neonatal intubation: what are we doing?
Conclusions: This neonatal manikin study identified three sections in the diagram of the forces applied during intubation, which likely mirrored the three main phases of intubation. Overall, the pattern of each section showed some differences in relation to the laryngoscope (direct or video) that was used during the procedure. These findings may provide useful insights for improving the understanding of the procedure.What is Known:• Neonatal intubation is a life-saving procedure that requires a skilled operator and may cause direct trauma to the  tissues and precipitate adverse reactions.• Intubation with a videolary...
Source: European Journal of Pediatrics - January 23, 2024 Category: Pediatrics Source Type: research

Quality of life and healthcare utilization during the COVID-19 pandemic are more restricted in chronically ill than in healthy children: a tertiary care children ’s hospital experience
Conclusion: Our findings underscore the importance of identifying families with chronically ill children as a vulnerable patient group with higher burdens during the COVID-19 pandemic and potential future pandemics. Healthcare providers may mitigate such burdens by ensuring reliable appointment allocation, offering contactless healthcare options, and providing tailored advice regarding vulnerabilities and preventive measures specific to their chronically ill children.What is Known:• The SARS-CoV-2 pandemic has led to significant restrictions in everyday life and both accessibility and utilization of healthcare for childr...
Source: European Journal of Pediatrics - January 23, 2024 Category: Pediatrics Source Type: research

Adherence to a healthy lifestyle behavior composite score and cardiometabolic risk factors in Spanish children from the CORALS cohort
Conclusions: Higher adherence to the healthy lifestyle behavior composite score was associated with lower waist circumference, FMI, other cardiometabolic risk factors, and risk of overweight or obesity in Spanish preschool children. Further studies are required to confirm these associations.What is Known:• Lifestyle is a well-recognized etiologic factor of obesity and its comorbidities.• Certain healthy behaviors such as adhering to a healthy diet, increasing physical activity, and decreasing screentime are strategies for prevention and treatment of childhood obesity.What is New:• Higher adherence to the healthy life...
Source: European Journal of Pediatrics - January 23, 2024 Category: Pediatrics Source Type: research

Greater rate of weight loss predicts paediatric hospital admission in adolescent typical and atypical anorexia nervosa
Conclusion: This study provides evidence on predictors of hospital admission, from a sample representing the London area. The assessment of weight loss speed, duration and magnitude are recommended as priority parameters that inform the risk of deterioration and the likelihood of hospital admission in adolescent AN and AAN. Further research investigating outcomes of these hospital admission is needed.What is Known:• Hospital admissions for eating disorders (ED) are rapidly increasing.• Limited research exists evidencing the factors that lead to hospital admissions, or their outcomes.What is New:• This study provides ...
Source: European Journal of Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research

Computerized adaptive testing to screen pre-school children for emotional and behavioral problems
Conclusion: A CAT is very promising for the identification of EB problems in pre-school children, as it seems to yield an efficient, yet high-quality identification. This conclusion should be confirmed by real-life administration of this CAT.What is Known:• Studies indicate the validity of using computerized adaptive test (CAT) applications to identify emotional and behavioral problems in school-aged children.• Evidence is as yet limited on whether CAT applications can also be used with pre-school children.What is New:• The results of this study show that a computerized adaptive test is very promising for the identif...
Source: European Journal of Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research

The risk of hospitalisation from RSV is not increased by co-infection in children under 24-months-of-age
Conclusion: This real-world data add to a growing consensus that RSV increases the risk of hospitalisation, while other co-infections, except for co-infection with SARS-CoV-2, do not. Given the timeframe over which our study was conducted, only a few children had SARS-CoV-2 co-infection, so we could not confirm any significant effect from this interaction.What is Known:• RSV increases the risk of hospitalisation and the need tor ventilatory support, especially in very young children.What is New:• Younger age and RSV infection were both associated with the need for hospitalisation and the duration of hospitalisation aft...
Source: European Journal of Pediatrics - January 20, 2024 Category: Pediatrics Source Type: research

Autonomic activity and cardiovascular system risk assessment in pediatric patients with hemolytic uremic syndrome
Conclusion: Patients with HUS may have autonomic nervous system dysfunction. HRV measurement is a non-invasive method that can evaluate this. It can be thought that there may be an increased risk of cardiovascular events and arrhythmias in some patients with HUS. ECG should be also considered to detect arrhythmia.What is Known:• Hemolytic uremic syndrome (HUS) primarily effects the hematologic parameters and kidney.• Secondary cardiomyopathy with hypertension and renal failure could be observed in these patients.• Rhythm problems are not expected primarily in these patients.• There is very limited data in evaluatin...
Source: European Journal of Pediatrics - January 19, 2024 Category: Pediatrics Source Type: research

Efficacy and safety of infliximab in the treatment of Kawasaki disease: A systematic review and meta-analysis
Conclusion: The meta-analysis demonstrates that infliximab alone is a well-tolerated and effective treatment for IVIG-resistant KD. The additional efficacy of infliximab to IVIG for initial treatment of KD is limited. More large and high-quality trials are needed to confirm the efficacy of infliximab, especially for intensification of primary treatment for KD.What is Known:• Infliximab is a novel monoclonal antibody specifically blocking tumor necrosis factor-alpha and is approved for treatment of several immune-mediated inflammatory disorders.• The efficacy of infliximab in treating children with Kawasaki disease is c...
Source: European Journal of Pediatrics - January 19, 2024 Category: Pediatrics Source Type: research

Criteria for discharge of preterm infants from Canadian neonatal intensive care units
Conclusion: There is a significant heterogeneity in discharge practices of preterm infants among Canadian NICUs. This survey provides a basis for benchmarking and knowledge sharing.What is Known:• Discharging preterm infants from the NICU impacts preterm infants, their families, and NICUs.• All efforts should ensure a safe transfer of care to parents, decrease the length of stay, better utilize resources, and improve parents’ satisfaction.What is New:• The discharge criteria of preterm infants vary widely among NICUs.• This survey provides benchmark information and exposes the need to better standardize discharge...
Source: European Journal of Pediatrics - January 19, 2024 Category: Pediatrics Source Type: research

Long-lasting effects of COVID-19 pandemic on hospitalizations and severity of bronchiolitis
Conclusions:  Compared to adults, COVID-19 in infants is often asymptomatic or mildly symptomatic and rarely results in hospitalization. This study indicates that the pandemic has indirectly induced an increased burden of bronchiolitis among hospitalized infants. This shift, which is not explained by the recog nized risk factors, suggests the existence of higher infant vulnerability during the last two seasons.What is known:• The pandemic led to a change in epidemiology of respiratory diseases• Large data on severity of bronchiolitis and underlying risk factors before and during COVID-19 pandemic are scarceWhat is n...
Source: European Journal of Pediatrics - January 18, 2024 Category: Pediatrics Source Type: research

Cardiac point-of-care ultrasound: Practical integration in the pediatric and neonatal intensive care settings
Conclusion: Cardiac POCUS is a technology and tool that reveals important real-time information at the bedside of the critically  ill child and infant. Understanding strengths and limitations of cardiac POCUS views and protocolizing an approach to answer focused clinical questions provides a framework for training and translation to clinical care.What is Known:• Ultrasound technology is now ubiquitous among pediatric critical care and neonatology settings, and growing literature supports an expanded role in not only procedural but also diagnostic applications.• Cardiac POCUS influences provider perception of pathophy...
Source: European Journal of Pediatrics - January 18, 2024 Category: Pediatrics Source Type: research

Use of point-of-care ultrasound (POCUS) to monitor neonatal and pediatric extracorporeal life support
Conclusion: Based on these considerations and on the lack of specific guidelines for the use of POCUS in the neonatal and pediatric ECMO setting, the aim of this paper is to provide a systematic overview for the application of POCUS during ECMO support in these populations.What is Known:• Extracorporeal membrane oxygenation (ECMO) provides advanced cardiopulmonary support for patients with refractory acute cardiac and/or respiratory failure and requires appropriate monitoring.• Point-of-care ultrasound (POCUS) is an accessible and adaptable tool to assess neonatal and pediatric cardiac and/or respiratory failure at bed...
Source: European Journal of Pediatrics - January 18, 2024 Category: Pediatrics Source Type: research

Differences in clinical characteristics of early-onset and late-onset severe acute respiratory syndrome coronavirus 2 infections in neonates
Conclusion: The clinical symptoms and rates of pneumonia caused by SARS-CoV-2 infection in neonates differed between the early-onset and late-onset groups. Different clinical management is necessary for neonates with early-onset and late-onset SARS-CoV-2 infections.What is Known:• Neonates are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).• Differences in clinical characteristics of early-onset and late-onset SARS-CoV-2 infections in neonates remain unclear.What is New:• Fever and cough were the most common symptoms among neonates with late-onset infection.• Neonates with late-onset SA...
Source: European Journal of Pediatrics - January 18, 2024 Category: Pediatrics Source Type: research