Vitamin D status modulates innate immune responses and metabolomic profiles following acute prolonged cycling
ConclusionThese findings provide evidence of the influence of vitamin D status on exercise-induced changes in parameters of innate immune defence and metabolomic signatures such as markers of inflammation and metabolic stress. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 30, 2023 Category: Nutrition Source Type: research

Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study
ConclusionOur findings suggest that distinguishing between “fasting” and “non-fasting” blood samples may be inadequate, and a more granular approach is warranted. This may have implications for how to account for dietary intake when blood sampling in both clinical and research settings. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 30, 2023 Category: Nutrition Source Type: research

The healthy beverage index is not associated with insulin resistance, prediabetes and type 2 diabetes risk in the Rotterdam Study
ConclusionOur findings suggest no major role for overall beverage intake quality assessed with the HBI in insulin resistance, prediabetes and T2D incidence. The HBI may not be an adequate tool to assess beverage intake quality in our population. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 30, 2023 Category: Nutrition Source Type: research

A short-term intervention of ingesting iron along with methionine and threonine leads to a higher hemoglobin level than that with iron alone in young healthy women: a randomized, double-blind, parallel-group, comparative study
ConclusionsIngestion of methionine and threonine with low doses of iron leads to a higher hemoglobin levels than that with iron alone in a short period of 4  weeks.Trial registrationUniversity Hospital Medical Information Network Clinical Trial Registry (UMIN000046621). (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 30, 2023 Category: Nutrition Source Type: research

Ameliorative effect of mussel-derived ACE inhibitory peptides on spontaneous hypertension rats
ConclusionOur findings demonstrate the potential use of MEPs as active components in functional foods designed to lower blood pressure. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 30, 2023 Category: Nutrition Source Type: research

The association of obesity-related dietary patterns and main food groups derived by reduced-rank regression with cardiovascular diseases incidence and all-cause mortality: findings from 116,711 adults
ConclusionsWe developed obesity-related DPs prospectively associated with increased risks of CVD and all-cause mortality. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

Aerobic exercise and vitamin E improve high-fat diet-induced NAFLD in rats by regulating the AMPK pathway and oxidative stress
ConclusionAerobic exercise and vitamin E supplementation can improve HFD-induced NAFLD in rats by regulating the AMPK pathway and reducing oxidative stress. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

Bacillus coagulans GBI-30, 6086 (BC30) improves lactose digestion in rats exposed to a high-lactose meal
ConclusionTreatment with BC30 improved the digestibility of lactose in an acute lactose challenge and ameliorated some of the parameters associated with lactose-induced malnutrition. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women ’s Circle of Health Study
ConclusionOur findings suggest that mTOR genetic variants may interact with energy intake in relation to breast cancer risk, including the ER − subtype, in Black women. Future studies should confirm these findings. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

Association of serum 25-hydroxyvitamin D with the incidence of 16 cancers, cancer mortality, and all-cause mortality among individuals with metabolic syndrome: a prospective cohort study
ConclusionThese findings emphasize the importance of 25(OH)D in cancer prevention and longevity promotion among patients with MetS. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

Metabolic signature of 13C-labeled wheat bran consumption related to gut fermentation in humans: a pilot study
ConclusionThis pilot study allowed to consider novel procedures for the development of biomarkers revealing dietary fiber-gut microbiota interactions. The non-invasive assessment of exhaled gas following13C-labeled fibers ingestion enabled to decipher distinct fermentation profiles: high-CH4 producers vs low-CH4 producers. The isotope labeling permits a specific in vivo characterisation of the dietary fiber impact consumption on microbiota metabolite production.Clinical trial registrationThe study has been registered under the number NCT03717311 at ClinicalTrials.gov on October 24, 2018. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

The effects of long-term almond consumption on whole-body insulin sensitivity, postprandial glucose responses, and 48  h continuous glucose concentrations in males and females with prediabetes: a randomized controlled trial
ConclusionsIn participants with prediabetes, long-term almond consumption showed adverse effects on insulin sensitivity and glucose metabolism. As almonds seemed not to have fully replaced other food items, it might be necessary to provide more supporting guidelines on how to incorporate energy-dense nuts into healthy diets to prevent type 2 diabetes development.Clinical Trial RegistrationThis clinical trial was registered in February 2018 as NCT03419702. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 11, 2023 Category: Nutrition Source Type: research

Dietary intakes of total, nonheme, and heme iron and hypertension risk: a longitudinal study from the China Health and Nutrition Survey
ConclusionsOur findings emphasize the importance of maintaining moderate iron intake in the prevention of hypertension. Both insufficient and excess intake of iron might increase the risk of hypertension. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 9, 2023 Category: Nutrition Source Type: research

The effect of vitamin K4 supplementation on insulin resistance in individuals with type 2 diabetes: a double-blind randomised placebo-controlled clinical trial
ConclusionVitamin K4 supplementation for 24  weeks is capable of improving insulin resistance and TG levels in individuals with type 2 diabetes. In addition, the improvement in insulin resistance was reflected in the decrease in antidiabetic medication doses. However, it did not affect fasting plasma glucose (FPG) or glycated haemoglobin (Hb A1c).Trial registrationThe study was registered on clinicaltrials.gov with ID: NCT04285450. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 8, 2023 Category: Nutrition Source Type: research

A diet containing cod backbone proteins attenuated the development of mesangial sclerosis and tubular dysfunction in male obese BTBR ob/ob mice
ConclusionA diet containing cod backbone protein powder attenuated the development of mesangial sclerosis and tubular dysfunction in obese BTBRob/ob mice, but did not prevent the development of glomerular hypertrophy and albuminuria in these mice. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - August 7, 2023 Category: Nutrition Source Type: research