Intravenous immunoglobulin for treatment of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy in France: are daily practices in accordance with guidelines?
ConclusionsThis was the first national study to describe the implementation of the European Federation of Neurological Sciences/Peripheral Nerve Society guidelines in the daily management of IVIGs in patients with MMN and CIDP in France. Efforts are needed to improve long ‐term tailored treatment and home treatment to reduce economic costs. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 15, 2018 Category: Neurology Authors: C. Rosier,
N. Graveline,
A. Lacour,
J. ‐C. Antoine,
J.‐P. Camdessanché Tags: Original Article Source Type: research
Central nervous system involvement in late ‐onset Pompe disease: clues from neuroimaging and neuropsychological analysis
ConclusionsIn this LOPD cohort the results showed morphological and functional brain alterations with mild neuropsychological dysfunction, mainly in the limb ‐girdle muscle weakness group. Cerebrovascular alterations seemed to be not related to common risk factors, suggesting a major role of enzymatic deficiency in the pathogenesis of brain abnormalities. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 15, 2018 Category: Neurology Authors: O. Musumeci,
S. Marino,
F. Granata,
R. Morabito,
L. Bonanno,
T. Brizzi,
V. Lo Buono,
F. Corallo,
M. Longo,
A. Toscano Tags: Original Article Source Type: research
Prognostic significance of genetic biomarkers in isocitrate dehydrogenase ‐wild‐type lower‐grade glioma: the need to further stratify this tumor entity – a meta‐analysis
The clinical outcomes ofisocitrate dehydrogenase‐wild‐type (IDH‐wt) lower‐grade glioma (LGG) have been the subject of debate for some time. In this meta‐analysis, we aimed to assess the prognostic values of several known genetic markers (e.g. TERT promoter mutation, H3F3A mutation, CDKN2A loss) in this tumor group. Four electronic databases, including Pub Med, Scopus, Web of Science and Virtual Health Library, were searched for relevant articles. Pooled hazard ratio (HR) and corresponding 95% confidence interval (CI) for overall survival were calculated using a random‐effect model weighted by an inverse varianc...
Source: European Journal of Neurology - November 13, 2018 Category: Neurology Authors: H. G. Vuong,
T. T. K. Tran,
H. T. T. Ngo,
T. Q. Pham,
T. Nakazawa,
K. ‐M. Fung,
L. Hassell,
R. Katoh,
T. Kondo Tags: Review Article Source Type: research
Sensitivity of MG ‐ADL for generalized weakness in myasthenia gravis
This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 12, 2018 Category: Neurology Authors: Robert H.P. de Meel,
Wouter F. Raadsheer,
Erik W. van Zwet,
Jan J.G.M. Verschuuren,
Martijn R. Tannemaat Tags: Short Communications Source Type: research
Executive function subdomains are associated with poststroke functional outcome and permanent institutionalization
ConclusionsEF was strongly associated with poststroke functional impairment. In follow ‐up, poor inhibition was related to earlier permanent institutionalization. Results suggest the prognostic value of EFs subdomains after stroke.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Hanna M Laakso,
Marja Hietanen,
Susanna Melkas,
Gerli Sibolt,
Sami Curtze,
Maarit Virta,
Raija Ylikoski,
Tarja Pohjasvaara,
Markku Kaste,
Timo Erkinjuntti,
Hanna Jokinen Tags: Original Article Source Type: research
Sapienza GLObal Bedside Evaluation of Swallowing after Stroke The GLOBE ‐3S study
ConclusionGLOBE ‐3S is quick to perform at bedside and can accurately identify aspiration in acute stroke patients. By including the measurement of laryngeal elevation and the monitoring of oxygen desaturation, it could represent a highly sensitive instrument to avoid the misdiagnosis of silent aspirators.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Massimiliano Toscano,
Alessandro Vigan ò,
Andrea Rea,
Angela Verzina,
Tullia Sasso D'Elia,
Francesca Puledda,
Lucia Longo,
Valentina Mancini,
Marco Ruggiero,
Tommaso B. Jannini,
Giada Giuliani,
Francesca Albino,
Marta Altieri,
Edoardo Vicenz Tags: Original Article Source Type: research
Association of Serum Galectin ‐3 with Risks of Death and Vascular Events in Acute Ischemic Stroke Patients: the Role of Hyperglycemia
ConclusionIncreased galectin ‐3 was associated with the primary outcome, stroke recurrence and vascular events within one‐year after stroke in the patients with hyperglycemia, suggesting that galectin‐3 may be an important prognostic factor for ischemic stroke patients with hyperglycemia.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Nimei Zeng,
Aili Wang,
Chongke Zhong,
Xiaowei Zheng,
Zhengbao Zhu,
Tan Xu,
Yanbo Peng,
Hao Peng,
Qunwei Li,
Zhong Ju,
Deqin Geng,
Yonghong Zhang,
Jiang He Tags: Original Article Source Type: research
Comparing Two Classification Schemes for Seizures and Epilepsy in Rural China
ConclusionsThe 1980's and 2017 classifications had 100% agreement in classifying focal seizures and epilepsy in rural China. A small but significant proportion of generalised seizures and epilepsy and aetiologies classified in the old classifications were re ‐classified to unknown in the new classifications. These results highlight the need for improvement in clinical evaluation of people with epilepsy in resource‐poor settings.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Feng Wang,
Zhibin Chen,
Indran Davagnanam,
Chandrashekar Hoskote,
Ding Ding,
Wenzhi Wang,
Bin Yang,
Yingli Wang,
Taiping Wang,
Wenling Li,
Josemir W. Sander,
Patrick Kwan Tags: Original Article Source Type: research
Hemorrhagic transformation after stroke: Interrater and intrarater agreement
ConclusionThe ECASS classification may involve too many categories and the diagnosis of HT may not be easily replicable, except in the presence of a large parenchymal hematoma.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Adrien Guenego,
Augustin Lecler,
Jean Raymond,
Candice Sabben,
Naim Khoury,
Kevin Premat,
Daniele Botta,
William Boisseau,
Benjamin Ma ïer,
Gabriele Ciccio,
Hocine Redjem,
Stanislas Smajda,
Célina Ducroux,
Lucas Di Meglio,
Vincent Davy,
J Tags: Original Article Source Type: research
Mitochondrial DNA haplogroups and age at onset of Machado ‐Joseph disease/Spinocerebellar ataxia type 3: a study in patients from multiple populations
ConclusionsThese findings suggest that JT, W and X haplogroups seem to modify age at onset in Machado ‐Joseph disease; replication studies should be performed in European populations, where the frequency of the candidate modifiers is similar.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: A. Ramos,
M. Planchat,
A R. Vieira Melo,
M. Raposo,
U. Shamim,
V. Suroliya,
A.K. Srivastava,
M. Faruq,
H. Morino,
R. Ohsawa,
H. Kawakami,
L.B. Jardim,
ML Saraiva ‐Pereira,
J. Vasconcelos,
C. Santos,
M. Lima Tags: Original Article Source Type: research
Clinical course of multiple sclerosis and labor ‐force absenteeism: a longitudinal population‐based study
ConclusionsPatients with RRMS have substantially lower levels of sick leave and disability pension over time compared with their counterparts with SPMS and PPMS, while labour ‐force absenteeism is similar for patients with SPMS and PPMS. These findings contribute to the understanding of the impact of MS on socio‐economic outcomes and help inform the discussion on the clinical classification of different courses of the disease.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Anna Castelo ‐Branco,
Erik Landfeldt,
Axel Svedbom,
Emil Löfroth,
Andrius Kavaliunas,
Jan Hillert Tags: Original Article Source Type: research
Increased rate of acute caesarean sections in women with epilepsy: Results from Oppland Perinatal Database in Norway
ConclusionWe found that women with epilepsy using AEDs during pregnancy have increased rate of acute CS, breech presentation and low birth weight, and that seizure frequency during pregnancy did not influence the complication rate.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Anette H. Farmen,
Jacob H. Grundt,
Jakob O. Nakling,
Petter Mowinckel,
Karl O. Nakken,
Morten I. Lossius Tags: Original Article Source Type: research
Dual Antiplatelet Therapy Reduced Stroke Risk in High ‐risk Transient Ischemic Attack Patients Assessed by ABCD3‐I Score
ConclusionsHigh ‐risk TIA patients assessed by ABCD3‐I score received the most pronounced clinical benefit from early use of dual antiplatelet therapy in the real‐clinical experience.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Bo Song,
Lulu Pei,
Yuan Cao,
Pei Chen,
Hui Fang,
Shilei Sun,
Xiao Wang,
Xuan Tian,
Yinan Guo,
Yuming Xu Tags: Original Article Source Type: research
Safety and efficacy of autologous hematopoietic stem cell transplantation following natalizumab discontinuation in aggressive Multiple Sclerosis
ConclusionThese data suggest that an aggressive therapy should be established after NTZ with the shortest possible wash ‐out period. AHSCT after six months from NTZ withdrawal seems safe.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: Alice Mariottini,
Chiara Innocenti,
Benedetta Forci,
Eliana Magnani,
Claudia Mechi,
Alessandro Barilaro,
Riccardo Nistri,
Arianna Fani,
Riccardo Saccardi,
Luca Massacesi,
Anna Maria Repice Tags: Original Article Source Type: research
Dimethyl fumarate and teriflunomide for multiple sclerosis in a real ‐life setting: a French retrospective cohort study
ConclusionIn this retrospective cohort study, DMF demonstrated significantly better efficacy over 2 years than teriflunomide, but tolerance to teriflunomide was better. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 9, 2018 Category: Neurology Authors: S. Cond é,
X. Moisset,
B. Pereira,
M. Zuel,
R. Colamarino,
M. Maillet‐Vioud,
M. Lauxerois,
F. Taithe,
P. Clavelou,
on behalf of the Réseau NeuroSEP Auvergne Tags: Original Article Source Type: research
