Pulmonary function and atherosclerosis in the general population: causal associations and clinical implications
AbstractReduced lung function is associated with cardiovascular mortality, but the relationships with atherosclerosis are unclear. The population-based Swedish CArdioPulmonary BioImage study measured lung function, emphysema, coronary CT angiography, coronary calcium, carotid plaques and ankle-brachial index in 29,593 men and women aged 50 –64 years. The results were confirmed using 2-sample Mendelian randomization. Lower lung function and emphysema were associated with more atherosclerosis, but these relationships were attenuated after adjustment for cardiovascular risk factors. Lung function was not associated with co...
Source: European Journal of Epidemiology - January 2, 2024 Category: Epidemiology Source Type: research
The need for Ignorance in cancer research
(Source: European Journal of Epidemiology)
Source: European Journal of Epidemiology - December 27, 2023 Category: Epidemiology Source Type: research
Chance, ignorance, and the paradoxes of cancer: Richard Peto on developing preventative strategies under uncertainty
AbstractDuring the early 1980s both cancer biology and epidemiological methods were being transformed. In 1984 the leading cancer epidemiologist Richard Peto – who, in 1981, had published the landmarkCauses of Cancer with Richard Doll – wrote a short chapter on “The need for ignorance in cancer research”, in which the worlds of epidemiology and speculative Darwinian biology met. His reflections on how evolutionary theory related to cancer have become known as “Peto’s paradox”, whilst his articulation of “black box e pidemiology” provided the logic of subsequent practice in the field. We reprint this spark...
Source: European Journal of Epidemiology - December 26, 2023 Category: Epidemiology Source Type: research
A note of thanks
(Source: European Journal of Epidemiology)
Source: European Journal of Epidemiology - November 27, 2023 Category: Epidemiology Source Type: research
Losing the Public, for Better or for Worse: A Lesson from John Everett Gordon (1890 –1983) and John Rodman Paul (1893–1971)
AbstractThe Covid-19 pandemic has laid bare a tension around scientific expertise that has major implications for the effectiveness of health systems. Critical engagement with this tension, however, is largely missing from the lessons and programs consolidating in the wake of the emergency. Lacking good frameworks for discussing the tension, the vague term “public trust” has proliferated into a buzzword that stands in for more articulate discussion. The tension between experts and the public is not new, however. It is useful to look back to the 1930s, when health experts identifying as “new epidemiologists” imagine...
Source: European Journal of Epidemiology - November 25, 2023 Category: Epidemiology Source Type: research
State-level economic uncertainty and cardiovascular disease deaths: evidence from the United States
This study examines the association between economic uncertainty and mortality from diseases of the circulatory system in the United States. We obtained monthly state-level mortality data from 2008 to 2017 and used indices capturing economic uncertainty from national/international sources and local sources. Panel data modelling was used to account for unobserved time-invariant differences between the states. Our findings suggest that economic uncertainty is independently linked to cardiovascular mortality. Uncertainty arising from national/international sources is associated with cardiovascular deaths, whereas the respecti...
Source: European Journal of Epidemiology - November 15, 2023 Category: Epidemiology Source Type: research
Authors ’ Reply: Interpreting epidemiologic studies of colorectal cancer prevention
(Source: European Journal of Epidemiology)
Source: European Journal of Epidemiology - November 10, 2023 Category: Epidemiology Source Type: research
Evidence-based policy-making - epidemiology as a key science for quality of life in society
(Source: European Journal of Epidemiology)
Source: European Journal of Epidemiology - November 8, 2023 Category: Epidemiology Source Type: research
