The growing role of genetics in the understanding of cardiovascular diseases: towards personalized medicine
With thanks to Amelia Meier-Batschelet, Johanna Huggler, and Martin Meyer for help with compilation of this article. (Source: European Heart Journal)
Source: European Heart Journal - May 21, 2021 Category: Cardiology Source Type: research
Broaden your horizons with the latest addition to the journal family, EHJ Open
(Source: European Heart Journal)
Source: European Heart Journal - May 14, 2021 Category: Cardiology Source Type: research
The central role of amygdala in stress-related cardiac diseases and an update on long-COVID
(Source: European Heart Journal)
Source: European Heart Journal - May 14, 2021 Category: Cardiology Source Type: research
The ongoing impact of COVID-19 on cardiovascular care
Last Spring, CardioPulse spoke to leading cardiologists from four continents to assess their views of the COVID-19 crisis and its impact on the fight against cardiovascular disease.1 One year on, we return to them for their updated assessment and thoughts. (Source: European Heart Journal)
Source: European Heart Journal - May 8, 2021 Category: Cardiology Source Type: research
StatinWISE sheds new light on statin-related muscle symptoms
Comment on ‘Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials’ published in theBritish Medical Journal (DOI:http://dx.doi.org/10.1136/bmj.n135). (Source: European Heart Journal)
Source: European Heart Journal - May 7, 2021 Category: Cardiology Source Type: research
New challenges in vascular biology and medicine: from unravelling the mechanisms of neointima formation to the prevention of amputations and of ischaemic stroke
(Source: European Heart Journal)
Source: European Heart Journal - May 7, 2021 Category: Cardiology Source Type: research
Leveraging clinical epigenetics in heart failure with preserved ejection fraction: a call for individualized therapies
AbstractDescribed as the ‘single largest unmet need in cardiovascular medicine’, heart failure with preserved ejection fraction (HFpEF) remains an untreatable disease currently representing 65% of new heart failure diagnoses. HFpEF is more frequent among women and associates with a poor prognosis and unsustainable healt hcare costs. Moreover, the variability in HFpEF phenotypes amplifies complexity and difficulties in the approach. In this perspective, unveiling novel molecular targets is imperative. Epigenetic modifications—defined as changes of DNA, histones, and non-coding RNAs (ncRNAs)—represent a molecular fra...
Source: European Heart Journal - May 5, 2021 Category: Cardiology Source Type: research
Dr John Joseph Gallagher (1943 –2020)
Last November, my mentor in clinical electrophysiology Dr Eric Prystowsky, informed me about the decease of his mentor, our good friend John Gallagher (seeFigure 1). John passed away from complications of Covid-19, 21 November 2020. This was such a shock to us all. John was a giant in our field of clinical electrophysiology. His contributions, particularly in understanding and treatment of the WPW syndrome was pivotal. He offered hope and cure to so many patients. Since he was also an outstanding teacher and trained so many fellows, he not only helped his own patients but innumerable patients worldwide. (Source: European Heart Journal)
Source: European Heart Journal - May 1, 2021 Category: Cardiology Source Type: research
Prediction of sudden death in the era of personalized medicine
(Source: European Heart Journal)
Source: European Heart Journal - May 1, 2021 Category: Cardiology Source Type: research
Corrigendum to: Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23
Eur Heart J 2021; doi:10.1093/eurheartj/ehab030 (Source: European Heart Journal)
Source: European Heart Journal - April 24, 2021 Category: Cardiology Source Type: research
Genome-wide association for heart failure: from discovery to clinical use
(Source: European Heart Journal)
Source: European Heart Journal - April 21, 2021 Category: Cardiology Source Type: research
The Year in Cardiovascular Medicine 2020: Valvular Heart Disease
Discussing the Year in Cardiovascular Medicine for 2020 in the field of valvular heart disease is Professor Helmut Baumgartner and Dr Javier Bermejo. Mark Nicholls reports (Source: European Heart Journal)
Source: European Heart Journal - April 21, 2021 Category: Cardiology Source Type: research
Music of the cosmos and the heart
Cardiologists and a musician join to discuss similarities between the non-linear arrangement of micro- and macro-cosmos phenomena, and their relation to philosophy (Pythagoras, Fibonacci), art, music (J.S. Bach and others), and analogies to the functional anatomy of cardiomyocytes (Source: European Heart Journal)
Source: European Heart Journal - April 21, 2021 Category: Cardiology Source Type: research
Emerging causes and risk factors of heart failure: amyloidosis, myocarditis, immune checkpoint inhibitors, air pollution, and visceral adipose tissue
(Source: European Heart Journal)
Source: European Heart Journal - April 21, 2021 Category: Cardiology Source Type: research
Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research
Conclusions Acknowledging the dynamic and evolving nature of less-invasive aortic valve therapies, further refinements of clinical research processes are required. The adoption of these updated and newly proposed VARC-3 endpoints and definitions will ensure homogenous event reporting, accurate adjudication, and appropriate comparisons of clinical research studies involving devices and new therapeutic strategies. (Source: European Heart Journal)
Source: European Heart Journal - April 19, 2021 Category: Cardiology Source Type: research
