Stress-associated neurobiological activity is linked with acute plaque instability via enhanced macrophage activity: a prospective serial 18F-FDG-PET/CT imaging assessment
ConclusionAmygA, AI, and HEMA were concordantly enhanced in patients with AMI, showing concurrent dynamic changes over time. These results raise the possibility that stress-associated neurobiological activity is linked with acute plaque instability via augmented macrophage activity and could be a potential therapeutic target for plaque inflammation in AMI. (Source: European Heart Journal)
Source: European Heart Journal - January 18, 2021 Category: Cardiology Source Type: research
Multisystem positron emission tomography: interrogating vascular inflammation, emotional stress, and bone marrow activity in a single scan
(Source: European Heart Journal)
Source: European Heart Journal - January 18, 2021 Category: Cardiology Source Type: research
Machine learning-guided phenotyping of dilated cardiomyopathy and treatment of heart failure by antisense oligonucleotides: the future has begun
(Source: European Heart Journal)
Source: European Heart Journal - January 18, 2021 Category: Cardiology Source Type: research
The Year in Cardiovascular Medicine 2020: Coronary Intervention
Focusing on The Year in Cardiovascular Medicine for 2020 in the field of coronary intervention is Professor Fernando Alfonso and Professor Javier Escaned. Mark Nicholls meets them (Source: European Heart Journal)
Source: European Heart Journal - January 17, 2021 Category: Cardiology Source Type: research
The cardiovascular –dialysis nexus: the transition to dialysis is a treacherous time for the heart
This article reviews how dialysis initiation modifies the interpretation of circulating biomarkers, alters the accuracy of CV imaging, and worsens prognosis. We advocate a multidisciplinary approach and outline the issues practitioners should consider to optimize CV care for this unique and vulnerable population during a perilous passage. (Source: European Heart Journal)
Source: European Heart Journal - January 17, 2021 Category: Cardiology Source Type: research
Women experiencing myocardial infarction at a young age have worse outcomes compared with men: only for non-cardiovascular deaths and when treated inadequately?
This commentary refers to ‘Women who experience a myocardial infarction at a young age have worse outcomes compared with men: the Mass General Brigham YOUNG-MI registry’, by E.M. DeFilippiset al., 2020;41:4127 –4137. (Source: European Heart Journal)
Source: European Heart Journal - January 17, 2021 Category: Cardiology Source Type: research
Changing the paradigm for post-MI cholesterol lowering from intensive statin monotherapy towards intensive lipid-lowering regimens and individualized care
This editorial refers to ‘Low-density lipoprotein cholesterol reduction and statin intensity in myocardial infarction patients and major adverse outcomes: a Swedish nationwide cohort study’††, by J. Schubertet al., on page243. (Source: European Heart Journal)
Source: European Heart Journal - January 17, 2021 Category: Cardiology Source Type: research
The year in cardiovascular medicine 2020: interventional cardiology
(Source: European Heart Journal)
Source: European Heart Journal - January 15, 2021 Category: Cardiology Source Type: research
Alcohol consumption, atrial fibrillation, and cardiovascular disease: finding the right balance
(Source: European Heart Journal)
Source: European Heart Journal - January 13, 2021 Category: Cardiology Source Type: research
Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes
Conclusions In contrast to other cardiovascular diseases such as HF, even modest habitual alcohol intake of 1.2 drinks/day was associated with an increased risk of AF, which needs to be considered in AF prevention. (Source: European Heart Journal)
Source: European Heart Journal - January 13, 2021 Category: Cardiology Source Type: research
Illuminating the path from genetics to clinical outcome in Brugada syndrome
(Source: European Heart Journal)
Source: European Heart Journal - January 13, 2021 Category: Cardiology Source Type: research
Risk stratification in Brugada syndrome: the challenge of the grey zone
(Source: European Heart Journal)
Source: European Heart Journal - January 11, 2021 Category: Cardiology Source Type: research
Learning whether to subtract beta-blockers: it ’s about time
Graphical AbstractProposed framework for foundational and provisional secondary prevention therapy over time in low-risk post-MI patients. Foundational therapies should be considered in all patients without contraindications, while provisional therapies should be considered in selected patients with comorbidities or post-infarction complications. The horizontal time axis proposes duration of therapies and timeframes for pharmacotherapeutic re-assessment, and should be responsive to the temporal evolution of post-MI risk and events. ADP, adenosine diphosphate receptor inhibitors; ASA, acetylsalicylic acid; CKD, chronic kidn...
Source: European Heart Journal - January 11, 2021 Category: Cardiology Source Type: research
Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish, nationwide cohort study
ConclusionsIn this nationwide cohort study of stable, optimally treated MI patients without HF, we found no long-term effect of BB treatment on CV prognosis following the patients from 3 months to 3 years after MI admission. (Source: European Heart Journal)
Source: European Heart Journal - January 11, 2021 Category: Cardiology Source Type: research
The new frontiers in prevention: from sports cardiology to spaceflight, and back to earth with cardiovascular disease and cancer
(Source: European Heart Journal)
Source: European Heart Journal - January 11, 2021 Category: Cardiology Source Type: research
