Peptide-based pore formation and cell membrane deformation: European Biophysics Journal Prizes at EBSA 2023
Eur Biophys J. 2023 Nov 23. doi: 10.1007/s00249-023-01691-8. Online ahead of print.ABSTRACTThe European Biophysics Journal Prizes awarded at the European Biophysical Societies Association (EBSA) Congress in Stockholm in the Summer of 2023 recognised papers published in 2020 and 2021 which made use of multiple complementing experimental, theoretical and computational approaches. One of the winning papers addressed the specific role of arginine residues within antimicrobial and cell-penetrating peptides, in promoting membrane defect stabilisation and pore formation. The other winning paper described the influence of atomic f...
Source: European Biophysics Journal : EBJ - November 23, 2023 Category: Physics Authors: Robert J C Gilbert Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Drug-ionic surfactant interactions: density, sound speed, spectroscopic, and electrochemical studies
Eur Biophys J. 2023 Nov 9. doi: 10.1007/s00249-023-01689-2. Online ahead of print.ABSTRACTThe failure of antibiotics against infectious diseases has become a global health issue due to the incessant use of antibiotics in the community and a lack of entry of new antibacterial drugs onto the market. The limited knowledge of biophysical interactions of existing antibiotics with bio-membranes is one of the major hurdles to design and develop more effective antibiotics. Surfactant systems are the simplest biological membrane models that not only mimic the cell membrane functions but are also used to investigate the biophysical ...
Source: European Biophysics Journal : EBJ - November 9, 2023 Category: Physics Authors: Muhammad Sohail Hafiz Muhammad Abd Ur Rahman Muhammad Nadeem Asghar Source Type: research

Annexin A5 stabilizes matrix vesicle-biomimetic lipid membranes: unravelling a new role of annexins in calcification
Eur Biophys J. 2023 Nov 8. doi: 10.1007/s00249-023-01687-4. Online ahead of print.ABSTRACTMatrix vesicles are a special class of extracellular vesicles thought to actively contribute to both physiologic and pathologic mineralization. Proteomic studies have shown that matrix vesicles possess high amounts of annexin A5, suggesting that the protein might have multiple roles at the sites of calcification. Currently, Annexin A5 is thought to promote the nucleation of apatitic minerals close to the inner leaflet of the matrix vesicles' membrane enriched in phosphatidylserine and Ca2+. Herein, we aimed at unravelling a possible a...
Source: European Biophysics Journal : EBJ - November 8, 2023 Category: Physics Authors: Claudio R Ferreira Marcos Ant ônio E Cruz Mayt ê Bolean Luiz Henrique da S Andrilli Jos é Luis Millan Ana Paula Ramos Massimo Bottini Pietro Ciancaglini Source Type: research

Correction to: Relation between flexibility and intrinsically disorder regions in thermosensitive TRP channels reveal allosteric effects
Eur Biophys J. 2023 Nov 7. doi: 10.1007/s00249-023-01690-9. Online ahead of print.NO ABSTRACTPMID:37934234 | DOI:10.1007/s00249-023-01690-9 (Source: European Biophysics Journal : EBJ)
Source: European Biophysics Journal : EBJ - November 7, 2023 Category: Physics Authors: Abigail Garc ía-Morales Nancy O Pulido Daniel Balleza Source Type: research

Correction to: Relation between flexibility and intrinsically disorder regions in thermosensitive TRP channels reveal allosteric effects
Eur Biophys J. 2023 Nov 7. doi: 10.1007/s00249-023-01690-9. Online ahead of print.NO ABSTRACTPMID:37934234 | DOI:10.1007/s00249-023-01690-9 (Source: European Biophysics Journal : EBJ)
Source: European Biophysics Journal : EBJ - November 7, 2023 Category: Physics Authors: Abigail Garc ía-Morales Nancy O Pulido Daniel Balleza Source Type: research

Stability of multilamellar lipid tubules in excess water
Eur Biophys J. 2023 Oct 26. doi: 10.1007/s00249-023-01686-5. Online ahead of print.ABSTRACTIn the lyotropic phase of lipids with excess water, multilamellar tubules (MLTs) grow from defects. A phenomenological model for the stability of MLTs is developed that is universal and independent of the underlying growth mechanisms of MLTs. The stability of MLTs implies that they are in hydrostatic equilibrium and stable as elastic objects that have compression and bending elasticity. The results show that even with solvent pressure differences of 0.1 atm, the density profile is not significantly altered, so suggesting the stabilit...
Source: European Biophysics Journal : EBJ - October 26, 2023 Category: Physics Authors: Tripta Bhatia Source Type: research