Decision-Making Measured by the Iowa Gambling Task in Patients with Alcohol Use Disorders Choosing Harm Reduction versus Relapse Prevention Program
Conclusion: This study confirms that the decision-making process of patients with an alcohol use disorder is impaired. However, the 2 groups differ on the IGT scores, despite comparable clinical and cognitive profiles. The patients ’ decision-making abilities could be a useful guide when developing therapeutic programs.Eur Addict Res (Source: European Addiction Research)
Source: European Addiction Research - May 5, 2019 Category: Addiction Source Type: research

The Degree of Multidimensional Severity of Alcohol Use Disorder among Treatment-Seeking Patients: Is There an Additive Effect of Parental Alcohol Use Disorder?
Conclusions: Exposure to parental AUD is strikingly high among treatment-seeking outpatients. Nonetheless, the additive effect has a modest impact on multidimensional addiction severity and is mostly related to psycho-social impairment among treatment-seeking male offspring.Eur Addict Res (Source: European Addiction Research)
Source: European Addiction Research - April 18, 2019 Category: Addiction Source Type: research

Influence of Gamma-Hydroxybutyric Acid-Use and Gamma-Hydroxybutyric Acid-Induced Coma on Affect and the Affective Network
Conclusions: GHB-use but in particular GHB-induced comas, are associated with altered emotion identification and hippocampal functioning. Awareness campaigns are required to raise consciousness about the adverse effects of GHB-induced comas on affect regulation, despite the absence of subjective side effects.Eur Addict Res (Source: European Addiction Research)
Source: European Addiction Research - April 18, 2019 Category: Addiction Source Type: research

Definition and Validity of the Construct “Problematic Khat Use”: A Systematic Review
Conclusion: Problematic khat use constitutes, but is not limited to, harms, increased use over time, and frequent engagement in other psychoactive substances misuse. Khat use is different from problematic khat use since it is occasional and used for prayer, social, and functional reasons. Strong empirical studies that could establish thresholds for patterns of problematic khat use and a culturally suitable problematic khat use measures that follows a bottom-up approach of scale development are warranted.Eur Addict Res (Source: European Addiction Research)
Source: European Addiction Research - April 16, 2019 Category: Addiction Source Type: research

A Four-Factor Model of Work Addiction: The Development of the Work Addiction Risk Test Revised
Conclusions: As a conclusion, the WART-R is suitable to be used as an indicator of work addiction based on clinically relevant symptom dimensions.Eur Addict Res 2019;25:145 –159 (Source: European Addiction Research)
Source: European Addiction Research - April 15, 2019 Category: Addiction Source Type: research

Feasibility and Acceptability of an Intervention Providing Computer-Generated Tailored Feedback to Target Alcohol Consumption and Depressive Symptoms in Proactively Recruited Health Care Patients and Reactively Recruited Media Volunteers: Results of a Pilot Study
Conclusion: The intervention was technically and logistically feasible, well accepted, and may have the potential to reduce hazardous drinking and depressive symptoms in different populations. Subsamples differed in terms of problem severity, motivation to change, intervention usage, pre-post changes, and attitudes toward the intervention, showing that intervention development should involve the intended target populations to avoid biased conclusions on intervention effectiveness and acceptability.Eur Addict Res 2019;25:119 –131 (Source: European Addiction Research)
Source: European Addiction Research - March 31, 2019 Category: Addiction Source Type: research

Smoking Behavior of Women Before, During, and after Pregnancy: Indicators of Smoking, Quitting, and Relapse
Conclusions: One of the key findings of this study suggests that it is essential that partners quit smoking before pregnancy and do not smoke during pregnancy. If partners continue smoking during pregnancy, they should quit smoking postpartum. Health care professionals can play an important role in addressing partners ’ smoking and giving them evidence-based cessation support before, during, and after pregnancy.Eur Addict Res 2019;25:132 –144 (Source: European Addiction Research)
Source: European Addiction Research - March 31, 2019 Category: Addiction Source Type: research

Thiamine Substitution in Alcohol Use Disorder: A Narrative Review of Medical Guidelines
Conclusion: Substitution of parenteral thiamine in individuals with suspected WE is a well-established treatment regimen. However, suggestions according to guidelines vary widely. Furthermore, hardly any evidence-based recommendations exist on a more general use of thiamine as a preventative intervention in individuals with AUD. Further research is of utmost importance to raise awareness for this potentially undervalued problem.Eur Addict Res 2019;25:103 –110 (Source: European Addiction Research)
Source: European Addiction Research - March 21, 2019 Category: Addiction Source Type: research

History of Lifetime Cannabis Use Is Associated with Better Cognition and Worse Real-World Functioning in Schizophrenia Spectrum Disorders
Conclusions: Lifetime cannabis use is associated with better working memory and processing speed and worse real-world functioning in the area of socially useful activities in patients with schizophrenia-related disorders. Clinicians should, therefore, be aware of it to provide patient-centred care in their daily clinical practice.Eur Addict Res 2019;25:111 –118 (Source: European Addiction Research)
Source: European Addiction Research - March 21, 2019 Category: Addiction Source Type: research

Attention-Deficit Hyperactivity Disorder Symptom Status in a Mixed Gender Population of Opioid-Maintained Prison Inmates
Conclusion: There is a need for assessment of ADHD and other psychiatric comorbidities in OMT prisoners. Evidence-based treatment should be routinely provided.Eur Addict Res 2019;25:80 –92 (Source: European Addiction Research)
Source: European Addiction Research - February 18, 2019 Category: Addiction Source Type: research

Identification and Assessment of Drug-User Groups Among Nightlife Attendees: Self-Reports, Breathalyzer-Tests and Oral Fluid Drug Tests
Conclusions: Despite some discrepancies between self-reports and biological tests, self-reports proved both suitable and useful in identification of substantively different drug-user typologies, potentially informing targeted policy responses. Still, methodological challenges associated with onsite studies of illicit drug use should be further explored.Eur Addict Res 2019;25:93 –102 (Source: European Addiction Research)
Source: European Addiction Research - February 18, 2019 Category: Addiction Source Type: research

Psychometric Properties of the AUDIT, AUDIT-C, CRAFFT and ASSIST-Y among Swedish Adolescents
Conclusion: Based on the current sample, ASSIST-Y and the CRAFFT performed better than AUDIT and AUDIT-C. Health-care clinics working with adolescents should carefully consider their choice of screening instruments.Eur Addict Res 2019;25:68 –77 (Source: European Addiction Research)
Source: European Addiction Research - February 6, 2019 Category: Addiction Source Type: research

Addiction Research and Socialpsychiatry Between Machiavelli and Modern Art
Eur Addict Res 2019;25:78 –79 (Source: European Addiction Research)
Source: European Addiction Research - February 6, 2019 Category: Addiction Source Type: research

Intravenous Misuse of Methadone, Buprenorphine and Buprenorphine-Naloxone in Patients Under Opioid Maintenance Treatment: A Cross-Sectional Multicentre Study
Conclusions: We offered new information on factors associated with intravenous OMT misuse, repeated misuse and ER admission in Italian patients under OMT. Our data indicate that BUP-NLX misuse is not different from that of BUP or MET. Choosing the more expensive BUP-NLX over MET will likely not lead to the expected reduction of the risk of injection misuse of the OMT. Instead of prescribing new and expensive OMT formulations, addiction unit physicians and medical personnel should better focus on patient ’s features that are associated with a higher likelihood of misuse. Care should be paid to concurrent benzodiazepin...
Source: European Addiction Research - January 31, 2019 Category: Addiction Source Type: research

Effect of Assertive Community Treatment for Patients with Substance Use Disorder: A Systematic Review
Conclusions: The results of the very few existing randomized control studies are mixed. Treatment engagement was higher for ACT in 4 datasets. One dataset reported higher service contact rates for the ACT group than for controls. In 2 datasets a positive effect on hospitalization rates was found. Higher fidelity to the ACT model appears to improve outcomes. Substance use reduced only in half of the datasets, of which only one showed a significant reduction in the ACT group. Overall, ACT is a promising approach that may be useful for promoting treatment engagement for patients with SUD. According to earlier studies on patie...
Source: European Addiction Research - January 31, 2019 Category: Addiction Source Type: research

DNA Methylation of the Leptin Gene Promoter is Altered by Chronic Alcohol Exposure in an Animal Model for Alcohol Dependence
The objective of our study was to investigate the dynamics of leptin gene promoter methylation during alcohol withdrawal and specific treatment in a rodent (rat) model for alcohol dependence. DNA methylation was measured using direct bisulfite sequencing at 0 h, 24 h, and 6 days of alcohol withdrawal as well as after treatment with alpha-melanocyte-stimulating hormone (alpha-MSH), Beta-Endorphin, or saline. We found significantly lower methylation levels in alcohol-consuming animals compared to alcohol-na ïve animals. During 6 days of alcohol deprivation, this difference in methylation vanished. Leptin methylation of ...
Source: European Addiction Research - January 16, 2019 Category: Addiction Source Type: research

Intrapretuvalisuse of Methadone, Buprenorphine and Buprenorphine-Naloxone in Patients Under Opioid Maintenance Treatment: A Cross-Sectional Multicentre Study
Conclusions: We offered new information on factors associated with intravenous OMT misuse, repeated misuse and ER admission in Italian patients under OMT. Our data indicate that BUP-NLX misuse is not different from that of BUP or MET. Choosing the more expensive BUP-NLX over MET will likely not lead to the expected reduction of the risk of injection misuse of the OMT. Instead of prescribing new and expensive OMT formulations, addiction unit physicians and medical personnel should better focus on patient ’s features that are associated with a higher likelihood of misuse. Care should be paid to concurrent benzodiazepin...
Source: European Addiction Research - January 13, 2019 Category: Addiction Source Type: research

Substance Abuse-Related Self-Stigma in Women with Substance Use Disorder and Comorbid Posttraumatic Stress Disorder
Conclusions: The progressive model of self-stigma could be confirmed in women with SUD and PTSD, but PTSD severity and childhood trauma did not directly affect this process. Self-stigma appears to be related to depression in a stronger way than PTSD is related to women with SUD and PTSD.Eur Addict Res 2019;25:20 –29 (Source: European Addiction Research)
Source: European Addiction Research - January 13, 2019 Category: Addiction Source Type: research

Gambling on Smartphones: A Study of a Potentially Addictive Behaviour in a Naturalistic Setting
Smartphone users engage extensively with their devices, on an intermittent basis for short periods of time. These patterns of behaviour have the potential to make mobile gambling especially perseverative. This paper reports the first empirical study of mobile gambling in which a simulated gambling app was used to measure gambling behaviour in phases of acquisition and extinction. We found that participants showed considerable perseverance in the face of continued losses that were linearly related to their prior engagement with the app. Latencies between gambles were associated with the magnitude of reinforcement; more posi...
Source: European Addiction Research - January 13, 2019 Category: Addiction Source Type: research

The Effects of Oxytocin on Withdrawal, Craving and Stress Response in Heroin-Dependent Patients: A Randomized, Double-Blind Clinical Trial
Opioid dependence is an increasing clinical and public health problem. Current pharmacotherapies have limited efficacy and cause serious side effects. Increasing bodies of evidences suggest the neuropeptide, oxytocin (OT), as a potential treatment for drug abuse disorders. The current study was designed to evaluate the effect of OT on withdrawal, craving and anxiety scores, cortisol and dehydroepiandrosterone sulphate (DHEAS) blood level in heroin-dependent male patients. This randomized, double-blind placebo-controlled clinical trial was conducted on 58 males with opioid dependence by Abstinence Center of Addictive People...
Source: European Addiction Research - January 13, 2019 Category: Addiction Source Type: research

Acknowledgement
Eur Addict Res 2018;24:312 (Source: European Addiction Research)
Source: European Addiction Research - January 2, 2019 Category: Addiction Source Type: research

Contents Vol. 24, 2018
Eur Addict Res 2018;24:I –IV (Source: European Addiction Research)
Source: European Addiction Research - January 2, 2019 Category: Addiction Source Type: research

European Addiction Research Award 2019
Eur Addict Res 2019;25:1 (Source: European Addiction Research)
Source: European Addiction Research - December 18, 2018 Category: Addiction Source Type: research

Early Predictors of Trajectories of Tobacco Use Level from Adolescence to Young Adulthood: A 16-Year Follow-Up of the TEMPO Cohort Study (1999 –2015)
Conclusions: Tobacco smoking trajectories from adolescence to adulthood are associated with early substance use initiation, parental smoking, and academic difficulties.Eur Addict Res 2019;25:2 –9 (Source: European Addiction Research)
Source: European Addiction Research - December 18, 2018 Category: Addiction Source Type: research

Expression Levels of the Tyrosine Hydroxylase Gene and Histone Modifications Around its Promoter in the Locus Coeruleus and Ventral Tegmental Area of Rats during Forced Abstinence from Morphine
Conclusions: Results of the present study, for the first time, demonstrate the involvement of histone H3 acetylation in the regulation of TH gene expression in the LC of rats during forced abstinence from morphine.Eur Addict Res 2018;24:304 –311 (Source: European Addiction Research)
Source: European Addiction Research - December 5, 2018 Category: Addiction Source Type: research

Nalmefene, Given as Needed, in the Routine Treatment of Patients with Alcohol Dependence: An Interventional, Open-Label Study in Primary Care
Conclusions: Patients with alcohol dependence treated in primary care with nalmefene, taken as needed, in conjunction with simple psychosocial support, significantly reduced their alcohol consumption. Treatment was well tolerated.Eur Addict Res 2018;24:293 –303 (Source: European Addiction Research)
Source: European Addiction Research - November 28, 2018 Category: Addiction Source Type: research

The LASSO Program in Oslo: Harm Reduction Using Buprenorphine-Naloxone (Suboxone ®) in a Low Threshold Setting
Conclusion: This study shows that BPNX is highly effective in treating marginalized heroin addicts in low threshold settings. Even during their first attempt, 76.4% completed induction. There were no cases of severe precipitated withdrawal. Prolonged lag time affected neither the length of first treatment nor the total treatment length. Individualized induction readiness approach and motivation were central to the above results.Eur Addict Res 2018;24:286 –292 (Source: European Addiction Research)
Source: European Addiction Research - November 22, 2018 Category: Addiction Source Type: research

Investigating Sex-Specific Characteristics of Nicotine Addiction Using Metabolic and Structural Magnetic Resonance Imaging
This study sought to examine the sex-specific influence of nicotine addiction on gamma amino butyric acid (GABA) and the white matter (WM) microstructure. Sixty healthy subjects (smokers/non-smokers) underwent structural and metabolic magnetic resonance imaging scans. Results showed alterations in WM integrity (measured as changes in fractional anisotropy [FA] and GABA in smokers versus non-smokers and females versus males. No overall significant smoking and sex-specific interactions were observed in this study. However, on comparing female smokers with female non-smokers, significantly higher GABA and FA values were obser...
Source: European Addiction Research - November 16, 2018 Category: Addiction Source Type: research

The Impact of Childhood Maltreatment on Age of Onset of Alcohol Use Disorder in Women
It is unclear whether exposure to childhood maltreatment is associated with the age of onset of alcohol use disorder (AUD). A group of socially stable women with AUD seeking treatment (n = 75) were interviewed using the Addiction Severity Index and the Mini International Neuropsychiatric Interview. They also filled out the Childhood Trauma Questionnaire-short form. Emotional abuse, sexual abuse and multiple childhood traumas were found to be associated with earlier onset of AUD. Multivariable linear regression analysis showed that independent predictors for an earlier onset of AUD were exposure to emotional abuse (beta = &...
Source: European Addiction Research - November 16, 2018 Category: Addiction Source Type: research

The Impact of the Opioid Antagonist Naloxone on Experimentally Induced Craving in Nicotine-Dependent Individuals
Conclusion: Naloxone influenced nicotine withdrawal and strengthened significantly by cue exposure, both on objective measurement and on craving scales. These findings suggest an involvement of the endogenous opioid system in the development and maintenance of nicotine dependence.Eur Addict Res 2018;24:255 –265 (Source: European Addiction Research)
Source: European Addiction Research - November 13, 2018 Category: Addiction Source Type: research

Cost-Effectiveness Analysis of Genotype-Guided Treatment Allocation in Patients with Alcohol Use Disorders Using Naltrexone or Acamprosate, Using a Modeling Approach
In conclusion, pharmacogenetic treatment allocation of AUD patients to naltrexone, based onOPRM1 genotype, can be a cost-effective strategy, and could have potential individual and societal benefits. However, more evidence on the impact of genotype-guided treatment allocation on relapse is needed to substantiate these conclusions, as there is contradictory evidence about the effectiveness ofOPRM1 genotyping.Eur Addict Res 2018;24:245 –254 (Source: European Addiction Research)
Source: European Addiction Research - November 1, 2018 Category: Addiction Source Type: research

Schema Modes and Personality Disorder Symptoms in Alcohol-Dependent and Cocaine-Dependent Patients
Substance use disorders (SUD) and personality disorders co-occur frequently. This relationship might be understood by studying schema modes (a key concept in Schema therapy), which explain the dysfunctions characterizing personality disorder patients. In the present study, we compared the schema modes and personality disorder symptoms between alcohol-dependent patients, cocaine-dependent patients and healthy controls. We found indications that specific schema modes are specific for SUD patients. However, no differences between specific subtypes of SUD patients (alcohol- vs. cocaine-dependent patients) could be found regard...
Source: European Addiction Research - October 5, 2018 Category: Addiction Source Type: research

Risky Alcohol Use: The Impact on Health Service Use
Conclusions: Risky drinkers use more expensive services, such as hospitals and emergency rooms, but not PHC services, which may suggest that prevention strategies and alcohol interventions should also be implemented in those settings.Eur Addict Res 2018;24:234 –244 (Source: European Addiction Research)
Source: European Addiction Research - October 5, 2018 Category: Addiction Source Type: research

Neurocognitive Functioning in Alcohol Use Disorder: Cognitive Test Results Do not Tell the Whole Story
Conclusion: Like other psychiatric patients, patients with AUD show marked neurocognitive impairments that seem to be aggravated by, for example, distraction and lack of effort. This tentatively suggests that performance only partly reflects cortical impairments in areas hosting neurocognitive faculties. Contextual factors deserve greater attention in patients with addiction. The cross-sectional design of our study limits conclusions relating to causality.Eur Addict Res (Source: European Addiction Research)
Source: European Addiction Research - August 28, 2018 Category: Addiction Source Type: research

Increased Risk-Taking Behaviour and Brain-Derived Neurotrophic Factor Val66Met Polymorphism Correlates to Decreased Serum Brain-Derived Neurotrophic Factor Level in Heroin Users
Conclusions: These results indicate that genetic variant Met66 decreased the serum BDNF levels in combination with self-reported risk-taking propensity among heroin users. If results of future work confirm the influence of this combined effect between neurotrophic genotype and risk-taking behaviour, 66Met carriers might require higher levels of intervention to overcome their drug use pattern and risky behaviour.Eur Addict Res 2018;24:189 –200 (Source: European Addiction Research)
Source: European Addiction Research - August 22, 2018 Category: Addiction Source Type: research

A Survey on the Medical Use of Cannabis in Europe: A Position Paper
Conclusion: The use of medical cannabis in Europe seems to be restricted mostly to the use of the cannabis extract, nabiximol. There is only limited use of the cannabis plant as such for medical purposes, possibly indicating a different scenario in Europe as compared to the USA.Position Statement: EUFAS as an umbrella association of European addiction societies stresses the need for further studies on the efficacy of medical cannabis and warrants for possible dangers associated with the increasing popularity of medical cannabis. We need regulations at European level concerning registration and medical indications, developm...
Source: European Addiction Research - August 22, 2018 Category: Addiction Source Type: research

A Matter of Rules? A Longitudinal Study of Parents ’ Influence on Young People’s Drinking Trajectories
Based on longitudinal survey data (2005, 2008, 2015), this paper investigates binge drinking among young people in Denmark. We analyse the relationship between parental alcohol rules in 2005 and the development of their children ’s heavy episodic drinking from age 15 to 25/26 using a multilevel approach to repeated measures. Two hypotheses are tested. The first is that young people from families with “strict” alcohol rules have a lower level of binge drinking than young people from families with lenient rules. However , given the cultural pressure on adolescents to drink heavily in Denmark, we also expect...
Source: European Addiction Research - August 22, 2018 Category: Addiction Source Type: research

Daclatasvir Plasma Levels in a Cohort of Patients with Hepatitis C Virus Infection Taking Methadone: A Prospective Analysis
Conclusion: We found a significant difference in DCV levels at 2 weeks and 1 month: 150 ng/mL in patients without MET and 313 ng/mL with MET at 2 weeks (p #x3c; 0.001), 149 and 279  ng/mL at 1 month (p = 0.006). DCV levels were lower in cirrhotic patients (p #x3c; 0.001); among cirrhotic patients we also evidenced higher DCV concentrations in patients receiving MET at 2 weeks, 1 and 2 months (p #x3c; 0.001,p = 0.005, andp = 0.031, respectively). In multivariate analysis, the only predictive factor associated with DCV plasma levels was the  presence of MET. The reason for this increased DCV exposure is unclear; on...
Source: European Addiction Research - August 10, 2018 Category: Addiction Source Type: research

Gender Differences in Anxiety and Depression before and after Alcohol Detoxification: Anxiety and Depression as Gender-Related Predictors of Relapse
Conclusions: In both genders, the psychopathological dimension that showed the most significant worsening at 6-month follow-up (i.e., anxiety in males and depression in females) was found to be a significant predictor of relapse at the 12-month follow-up.Eur Addict Res 2018;24:163 –172 (Source: European Addiction Research)
Source: European Addiction Research - July 17, 2018 Category: Addiction Source Type: research

Long-Term Opioid Agonist Treatment Participation after First Treatment Entry is Similar across 4 European Regions but Lower in Non-Nationals
Heroin users in opioid agonist treatment (OAT) show markedly reduced heroin consumption, less crime and a lower mortality rate. However, the extent of long-term OAT participation over subsequent treatment episodes remains unclear. We analysed the annual proportion of patients in treatment  (at least 1 day) since the start of first OAT in 4 European regions: Barcelona (BA) 1996–2012: 8,602 patients; Czech ­Republic (CZ) 2000–2014: 4,377 patients; Netherlands (NL) 1994–2014: 33,235 patients, Zurich (ZU) 1992–2015: 11,795. We estimated the long-term decline of treatment need d ue to mortality ...
Source: European Addiction Research - July 17, 2018 Category: Addiction Source Type: research

The Clinical Efficacy of Mindfulness-Based Treatments for Alcohol and Drugs Use Disorders: A Meta-Analytic Review of Randomized and Nonrandomized Controlled Trials
Conclusion: MBIs seemed to show clinically significant advantages compared to other clinical approaches in relation to specific primary and secondary outcomes. Conversely, treatment retention was independent of the therapeutic approach.Eur Addict Res 2018;24:137 –162 (Source: European Addiction Research)
Source: European Addiction Research - July 17, 2018 Category: Addiction Source Type: research

Executive Impairments in Binge Drinking: Evidence for a Specific Performance-Monitoring Difficulty during Alcohol-Related Processing
This study evaluated inhibition and performance-monitoring abilities through the explicit processing of alcohol cues. Twenty-two binge drinkers (BD) and 22 control participants performed a speeded Go/No-Go task using pictures of alcohol and soft cans as Go and No-Go targets. This task measures inhibitory control and performance monitoring (i.e., task adjustment through errors and feedback processing) during the explicit processing of alcohol cues. Groups did not significantly differ regarding inhibition abilities. However, BD had poorer performance-monitoring abilities, reflected by a difficulty to adjust after errors, esp...
Source: European Addiction Research - July 3, 2018 Category: Addiction Source Type: research

Early Screening for Posttraumatic Stress Disorder in Inpatient Detoxification and Motivation Treatment: Results and Consequences
Conclusions: Early and systematic evaluation of PTSD in SUD inpatient detoxification treatment is largely safe and yields important information for individual treatment. The high PTSD-rate and the high symptom load in SUD patients during inpatient detoxification treatment highlight the need for a more stringent address of trauma/PTSD in early SUD treatment.Eur Addict Res 2018;24:128 –136 (Source: European Addiction Research)
Source: European Addiction Research - July 3, 2018 Category: Addiction Source Type: research

Quantitative Criteria to Screen for Cannabis Use Disorder
Conclusion: Frequency and quantity should be considered when exploring cannabis risks. A 1 SJU per day is proposed as a preliminary quantitative-based criterion to screen users with at least a moderate risk for CUD.Eur Addict Res 2018;24:109 –117 (Source: European Addiction Research)
Source: European Addiction Research - June 27, 2018 Category: Addiction Source Type: research

The European Innovation Express: Wim van den Brink Retires as Editor in Chief of European Addiction Research and Will Be Succeeded by Anna E. Goudriaan
Eur Addict Res 2018;24:107 –108 (Source: European Addiction Research)
Source: European Addiction Research - June 18, 2018 Category: Addiction Source Type: research

The Association between the Level of Plasma Oxytocin and Craving among Former Heroin Users
Conclusion: This finding may be taken into account in future studies and may provide a basis for the development of potential treatment for addiction. The effect of oxytocin for the treatment of opioid dependence might be modulated by some psychological factors.Eur Addict Res 2018;24:71 –78 (Source: European Addiction Research)
Source: European Addiction Research - June 14, 2018 Category: Addiction Source Type: research

Is Cannabis Use Treatment Also Indicated for Patients with Low to Moderate Polysubstance Use
Conclusions: CU treatment is also effective for patients with moderate PSU. However, treatment effects may be enhanced by addressing specific PSU characteristics as part of a modularized program.Eur Addict Res 2018;24:79 –87 (Source: European Addiction Research)
Source: European Addiction Research - June 14, 2018 Category: Addiction Source Type: research

Comment on “Methadone Dose Adjustments, Plasma R-Methadone Levels and Therapeutic Outcome of Heroin Users: A Randomized Clinical Trial”
Eur Addict Res 2018;24:88 (Source: European Addiction Research)
Source: European Addiction Research - June 14, 2018 Category: Addiction Source Type: research

Response to Letter to the Editor by Ernesto de Bernadis
Eur Addict Res 2018;24:89 –90 (Source: European Addiction Research)
Source: European Addiction Research - June 14, 2018 Category: Addiction Source Type: research

Predictors of Utilization of an Addiction-Specific Behavioural Couple Therapy in Alcohol Dependence
Conclusions: Certain subgroups of patients with AD are less likely to participate in BCT during inpatient treatment.Eur Addict Res 2018;24:91 –97 (Source: European Addiction Research)
Source: European Addiction Research - June 14, 2018 Category: Addiction Source Type: research