Anti-Seizure Medications on Trial Again: Accused of Parkinson's Disease!
Epilepsy Curr. 2023 Jun 13;23(5):277-279. doi: 10.1177/15357597231180068. eCollection 2023 Sep-Oct.NO ABSTRACTPMID:37901782 | PMC:PMC10601026 | DOI:10.1177/15357597231180068 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Rani A Sarkis Source Type: research
AI-nalyzing Mouse Behavior to Combat Epilepsy
Epilepsy Curr. 2023 Jul 7;23(5):315-317. doi: 10.1177/15357597231185215. eCollection 2023 Sep-Oct.NO ABSTRACTPMID:37901783 | PMC:PMC10601027 | DOI:10.1177/15357597231185215 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Yuliya Voskobiynyk Jeanne T Paz Source Type: research
Mechanisms of Neurostimulation for Epilepsy
Epilepsy Curr. 2023 Oct 15;23(5):298-302. doi: 10.1177/15357597231191887. eCollection 2023 Sep-Oct.ABSTRACTThis review discusses the use of neurostimulation therapies for epilepsy treatment, including vagal nerve stimulation, responsive neurostimulation, and deep brain stimulation. Different therapeutic strategies and their underlying mechanisms are explored, with a focus on optimizing parameters for seizure reduction. The review also highlights the paradigm shift toward a more diverse and multimodal approach to deep brain neuromodulation.PMID:37901784 | PMC:PMC10601041 | DOI:10.1177/15357597231191887 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Sheela Toprani Dominique M Durand Source Type: research
Epilepsy, Cardiovascular Risks, and Dementia: A M énage à Trois
Epilepsy Curr. 2023 Aug 9;23(5):283-285. doi: 10.1177/15357597231189588. eCollection 2023 Sep-Oct.NO ABSTRACTPMID:37901785 | PMC:PMC10601029 | DOI:10.1177/15357597231189588 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Ifrah Zawar Source Type: research
More Than Meets the Eye: Human Versus Computer in the Neuroimaging of Temporal Lobe Epilepsy
Epilepsy Curr. 2023 Sep 4;23(5):289-290. doi: 10.1177/15357597231193298. eCollection 2023 Sep-Oct.NO ABSTRACTPMID:37901786 | PMC:PMC10601035 | DOI:10.1177/15357597231193298 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Peter Widdess-Walsh Source Type: research
Don't Give Me Lip: A Role for Lipid-Accumulated Reactive Astrocytes in Temporal Lobe Epilepsy
Epilepsy Curr. 2023 Jun 27;23(5):321-323. doi: 10.1177/15357597231182785. eCollection 2023 Sep-Oct.NO ABSTRACTPMID:37901787 | PMC:PMC10601037 | DOI:10.1177/15357597231182785 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Evan C Rosenberg Ethan M Goldberg Source Type: research
The ECHO Was Heard Throughout the School
Epilepsy Curr. 2023 Jun 21;23(5):296-297. doi: 10.1177/15357597231181888. eCollection 2023 Sep-Oct.NO ABSTRACTPMID:37901788 | PMC:PMC10601032 | DOI:10.1177/15357597231181888 (Source: Epilepsy Curr)
Source: Epilepsy Curr - October 30, 2023 Category: Neurology Authors: Danielle A Becker Source Type: research
Electrical stimulation of the peripheral and central vestibular system
Curr Opin Neurol. 2023 Oct 26. doi: 10.1097/WCO.0000000000001228. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Electrical stimulation of the peripheral and central vestibular system using noninvasive (galvanic vestibular stimulation, GVS) or invasive (intracranial electrical brain stimulation, iEBS) approaches have a long history of use in studying self-motion perception and balance control. The aim of this review is to summarize recent electrophysiological studies of the effects of GVS, and functional mapping of the central vestibular system using iEBS in awake patients.RECENT FINDINGS: The use of GVS has become incre...
Source: Epilepsy Curr - October 27, 2023 Category: Neurology Authors: Christophe Lopez Kathleen E Cullen Source Type: research
Electrical stimulation of the peripheral and central vestibular system
Curr Opin Neurol. 2023 Oct 26. doi: 10.1097/WCO.0000000000001228. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Electrical stimulation of the peripheral and central vestibular system using noninvasive (galvanic vestibular stimulation, GVS) or invasive (intracranial electrical brain stimulation, iEBS) approaches have a long history of use in studying self-motion perception and balance control. The aim of this review is to summarize recent electrophysiological studies of the effects of GVS, and functional mapping of the central vestibular system using iEBS in awake patients.RECENT FINDINGS: The use of GVS has become incre...
Source: Epilepsy Curr - October 27, 2023 Category: Neurology Authors: Christophe Lopez Kathleen E Cullen Source Type: research
Electrical stimulation of the peripheral and central vestibular system
Curr Opin Neurol. 2023 Oct 26. doi: 10.1097/WCO.0000000000001228. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Electrical stimulation of the peripheral and central vestibular system using noninvasive (galvanic vestibular stimulation, GVS) or invasive (intracranial electrical brain stimulation, iEBS) approaches have a long history of use in studying self-motion perception and balance control. The aim of this review is to summarize recent electrophysiological studies of the effects of GVS, and functional mapping of the central vestibular system using iEBS in awake patients.RECENT FINDINGS: The use of GVS has become incre...
Source: Epilepsy Curr - October 27, 2023 Category: Neurology Authors: Christophe Lopez Kathleen E Cullen Source Type: research
Noradrenaline tracks emotional modulation of attention in human amygdala
Curr Biol. 2023 Oct 18:S0960-9822(23)01355-6. doi: 10.1016/j.cub.2023.09.074. Online ahead of print.ABSTRACTThe noradrenaline (NA) system is one of the brain's major neuromodulatory systems; it originates in a small midbrain nucleus, the locus coeruleus (LC), and projects widely throughout the brain.1,2 The LC-NA system is believed to regulate arousal and attention3,4 and is a pharmacological target in multiple clinical conditions.5,6,7 Yet our understanding of its role in health and disease has been impeded by a lack of direct recordings in humans. Here, we address this problem by showing that electrochemical estimates of...
Source: Epilepsy Curr - October 24, 2023 Category: Neurology Authors: Dan Bang Yi Luo Leonardo S Barbosa Seth R Batten Beniamino Hadj-Amar Thomas Twomey Natalie Melville Jason P White Alexis Torres Xavier Celaya Priya Ramaiah Samuel M McClure Gene A Brewer Robert W Bina Terry Lohrenz Brooks Casas Pearl H Chiu Marina Vannucc Source Type: research
Noradrenaline tracks emotional modulation of attention in human amygdala
Curr Biol. 2023 Oct 18:S0960-9822(23)01355-6. doi: 10.1016/j.cub.2023.09.074. Online ahead of print.ABSTRACTThe noradrenaline (NA) system is one of the brain's major neuromodulatory systems; it originates in a small midbrain nucleus, the locus coeruleus (LC), and projects widely throughout the brain.1,2 The LC-NA system is believed to regulate arousal and attention3,4 and is a pharmacological target in multiple clinical conditions.5,6,7 Yet our understanding of its role in health and disease has been impeded by a lack of direct recordings in humans. Here, we address this problem by showing that electrochemical estimates of...
Source: Epilepsy Curr - October 24, 2023 Category: Neurology Authors: Dan Bang Yi Luo Leonardo S Barbosa Seth R Batten Beniamino Hadj-Amar Thomas Twomey Natalie Melville Jason P White Alexis Torres Xavier Celaya Priya Ramaiah Samuel M McClure Gene A Brewer Robert W Bina Terry Lohrenz Brooks Casas Pearl H Chiu Marina Vannucc Source Type: research
Epilepsy in gliomas: recent insights into risk factors and molecular pathways
Curr Opin Neurol. 2023 Oct 2. doi: 10.1097/WCO.0000000000001214. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to discuss the molecular pathways governing the development of seizures in glioma patients.RECENT FINDINGS: The intrinsic epileptogenicity of the neuronal component of glioneuronal and neuronal tumors is the most relevant factor for seizure development. The two major molecular alterations behind epileptogenicity are the rat sarcoma virus (RAS)/mitogen-activated protein kinase / extracellular signal-regulated kinase (MAPK/ERK) and phosphatidylinositol-3-kinase / protein kinase B / m...
Source: Epilepsy Curr - October 22, 2023 Category: Neurology Authors: Roberta Rud à Francesco Bruno Alessia Pellerino Source Type: research
Epilepsy in gliomas: recent insights into risk factors and molecular pathways
Curr Opin Neurol. 2023 Oct 2. doi: 10.1097/WCO.0000000000001214. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to discuss the molecular pathways governing the development of seizures in glioma patients.RECENT FINDINGS: The intrinsic epileptogenicity of the neuronal component of glioneuronal and neuronal tumors is the most relevant factor for seizure development. The two major molecular alterations behind epileptogenicity are the rat sarcoma virus (RAS)/mitogen-activated protein kinase / extracellular signal-regulated kinase (MAPK/ERK) and phosphatidylinositol-3-kinase / protein kinase B / m...
Source: Epilepsy Curr - October 22, 2023 Category: Neurology Authors: Roberta Rud à Francesco Bruno Alessia Pellerino Source Type: research
Epilepsy in gliomas: recent insights into risk factors and molecular pathways
Curr Opin Neurol. 2023 Oct 2. doi: 10.1097/WCO.0000000000001214. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to discuss the molecular pathways governing the development of seizures in glioma patients.RECENT FINDINGS: The intrinsic epileptogenicity of the neuronal component of glioneuronal and neuronal tumors is the most relevant factor for seizure development. The two major molecular alterations behind epileptogenicity are the rat sarcoma virus (RAS)/mitogen-activated protein kinase / extracellular signal-regulated kinase (MAPK/ERK) and phosphatidylinositol-3-kinase / protein kinase B / m...
Source: Epilepsy Curr - October 22, 2023 Category: Neurology Authors: Roberta Rud à Francesco Bruno Alessia Pellerino Source Type: research
