Insomnia in epilepsy is associated with nocturnal seizures and anxiety
CONCLUSION: PWE with insomnia are more likely to experience depression and EDS. Nocturnal seizures and anxiety are identified as independent factors associated with insomnia in PWE. Furthermore, Anxiety has a greater impact on insomnia in PWE and the likelihood of insomnia has increased significantly with the aggravation of anxiety levels.PMID:38035537 | DOI:10.1016/j.yebeh.2023.109559 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - November 30, 2023 Category: Neurology Authors: Bofei Tan Qiang Liu Yameng Qin Qiuyan Chen Rong Chen Yanzi Jin Mengyun Li Xiaodan Jia Xianrui Xu Qing Zhang Source Type: research
Non-pharmacological therapeutic needs in people with Dravet syndrome
Epilepsy Behav. 2023 Nov 29;150:109553. doi: 10.1016/j.yebeh.2023.109553. Online ahead of print.ABSTRACTDravet syndrome (DS) is a genetic rare disease, which is usually caused by a mutation in the SCN1A gene. DS is characterised by a drug-resistant epilepsy and by cognitive and behavioural disturbances. Thus, DS patients require both pharmacological and non-pharmacological treatments. However, there is a paucity of studies on non-pharmacological therapies and their potential benefits. The main aim of this study was to describe the non-pharmacological therapy modalities received by DS patients and their socio-economic impac...
Source: Epilepsy and Behaviour - November 30, 2023 Category: Neurology Authors: Carla Ballesteros-Sayas Alicia Mu ñoz-Montero Simona Giorgi Elena Cardenal-Mu ñoz Eulalia Tur ón-Viñas Federico Pallard ó Jos é Ángel Aibar Source Type: research
Using design thinking to strengthen the community pharmacist's role in epilepsy care
This study used design thinking. Three patient personas were created based on previous research: a newly diagnosed PWE, a well-controlled PWE, and a complex PWE with uncontrolled seizures. An intervention prototype was developed for each of the three personas. Structured interviews were conducted with pharmacists, pharmacy students, patients with diagnosed epilepsy, and caregivers to elicit feedback on which features of each intervention prototype were desirable, feasible, and viable. Interviews were analyzed using rapid content analysis. A multidisciplinary advisory group and the research team prioritized features of the ...
Source: Epilepsy and Behaviour - November 30, 2023 Category: Neurology Authors: Sabra Zaraa H Steve White Andy Stergachis Edward J Novotny Chris Protos Grant Simic Jennifer L Bacci Source Type: research
Early antiseizure medication withdrawal and risk of seizure recurrence in children after epilepsy surgery: A retrospective study
This study included 145 children with a median follow-up duration of 40 months. Early ASM tapering was attempted postoperatively in 99 (68.3 %) children. Postoperative ASM discontinuation was attempted in 87 (60.0 %) children. Nine (9.1 %) children experienced seizure recurrence during the ASM reduction stage, and 10 (11.5 %) experienced recurrence after ASM discontinuation. Incomplete resection (P = 0.003) and postoperative seizures before ASM tapering (P = 0.003) were independent predictors of seizure recurrence during and after early ASM withdrawal.SIGNIFICANCE: ASM withdrawal is viable and safe to be initiated in child...
Source: Epilepsy and Behaviour - November 29, 2023 Category: Neurology Authors: YuXin Wu ZaiYu Zhang Ping Liang Bin Zou Difei Wang XuanXuan Wu Xuan Zhai Source Type: research
Early antiseizure medication withdrawal and risk of seizure recurrence in children after epilepsy surgery: A retrospective study
This study included 145 children with a median follow-up duration of 40 months. Early ASM tapering was attempted postoperatively in 99 (68.3 %) children. Postoperative ASM discontinuation was attempted in 87 (60.0 %) children. Nine (9.1 %) children experienced seizure recurrence during the ASM reduction stage, and 10 (11.5 %) experienced recurrence after ASM discontinuation. Incomplete resection (P = 0.003) and postoperative seizures before ASM tapering (P = 0.003) were independent predictors of seizure recurrence during and after early ASM withdrawal.SIGNIFICANCE: ASM withdrawal is viable and safe to be initiated in child...
Source: Epilepsy and Behaviour - November 29, 2023 Category: Neurology Authors: YuXin Wu ZaiYu Zhang Ping Liang Bin Zou Difei Wang XuanXuan Wu Xuan Zhai Source Type: research
