Identification of DNA methylation of < em > CAPN10 < /em > gene changes in the patients with type 2 diabetes mellitus as a predictive biomarker instead of HbA1c, random blood sugar, lipid profile, kidney function test, and some risk factors
Conclusion. These results indicate that DNA methylation changes in the CAPN10 gene promoter region may be used as a potential predictive biomarker to diagnose T2DM; however, this study requires further data to support this evidence.PMID:37823570 | DOI:10.2478/enr-2023-0025 (Source: Endocrine Regulations)
Source: Endocrine Regulations - October 12, 2023 Category: Endocrinology Authors: Harem Othman Smail Dlnya Asaad Mohamad Source Type: research
Correlation of leucocyte and platelet indices in patients with type 2 diabetes mellitus with microvascular complications at a tertiary care hospital in south India - A prospective cross-sectional study
Conclusions. Since no significant correlation was found between the different platelet indices and microvascular complications, it is evident that these markers cannot be used as the predictors of microvascular complications in T2DM patients.PMID:37823571 | DOI:10.2478/enr-2023-0026 (Source: Endocrine Regulations)
Source: Endocrine Regulations - October 12, 2023 Category: Endocrinology Authors: Raj Gokul Chidambaram Yoganathan Christopher Paul Clement Jenil Dhas Nekkanti Abilash Petchiappan Velammal Kumar Bhargavi Sivaraj Sujith Kumar Source Type: research
Oxidative stress in liver of streptozotocin-induced diabetic mice fed a high-fat diet: A treatment role of < em > Artemisia annua < /em > L
Conclusion. Therapeutic effects of AA on liver dysfunction showed that antioxidant activity of hot-water and alcoholic AA extracts were similar or higher than of metformin.PMID:37823572 | DOI:10.2478/enr-2023-0027 (Source: Endocrine Regulations)
Source: Endocrine Regulations - October 12, 2023 Category: Endocrinology Authors: Mahshid Ghanbari Mohammad Shokrzadeh Lamuki Forouzan Sadeghimahalli Emran Habibi Mohammad Reza Sayedi Moqadam Source Type: research
Hypoxia controls the expression of genes responsible for serine synthesis in U87MG cells on ERN1-dependent manner
Conclusion. The results of the present study demonstrate that the expression of genes responsible for serine synthesis is sensitive to hypoxia in gene-specific manner and that ERN1 knockdown significantly modifies the impact of hypoxia on the expression of PHGDH, PSAT1, PSPH, and ATF4 genes in glioblastoma cells and reflects the ERN1-mediated reprograming of hypoxic regulation at gene expression level.PMID:37823569 | DOI:10.2478/enr-2023-0028 (Source: Endocrine Regulations)
Source: Endocrine Regulations - October 12, 2023 Category: Endocrinology Authors: Myroslava Y Sliusar Dmytro O Minchenko Olena O Khita Dariia O Tsymbal Yuliia M Viletska Olha Y Luzina Serhij V Danilovskyi Oksana O Ratushna Oleksandr H Minchenko Source Type: research
Identification of DNA methylation of < em > CAPN10 < /em > gene changes in the patients with type 2 diabetes mellitus as a predictive biomarker instead of HbA1c, random blood sugar, lipid profile, kidney function test, and some risk factors
Conclusion. These results indicate that DNA methylation changes in the CAPN10 gene promoter region may be used as a potential predictive biomarker to diagnose T2DM; however, this study requires further data to support this evidence.PMID:37823570 | DOI:10.2478/enr-2023-0025 (Source: Endocrine Regulations)
Source: Endocrine Regulations - October 12, 2023 Category: Endocrinology Authors: Harem Othman Smail Dlnya Asaad Mohamad Source Type: research
