Endocrine Disruptors and Health Effects in Africa: A Call for Action
Conclusion:
To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774
Received: 16 February 2017
Revised: 22 May 2017
Accepted: 24 May 2017
Published: 22 August 2017
Address correspond...
Source: EHP Research - August 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride
Conclusions:
Mitochondrial inhibition in vitro occurred at a CPC concentration that may be relevant to human exposures. The antiestrogenic activity of CPC, BAK, rotenone, and triclosan may be related to their mitochondrial inhibitory activity. Our findings support the need for additional research on the mitochondrial inhibitory and antiestrogenic effects of QUATS, including CPC and BAK. https://doi.org/10.1289/EHP1404
Received: 22 November 2016
Revised: 04 May 2017
Accepted: 09 May 2017
Published: 22 August 2017
Address correspondence to G. Cortopassi, 1089 Veterinary Medicine Drive, Davis, CA 95616 USA. Phone: (530)...
Source: EHP Research - August 22, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Influence of Tetrabromobisphenol A, with or without Concurrent Triclosan, upon Bisphenol A and Estradiol Concentrations in Mice
Conclusion:
These data indicate that TBBPA, triclosan, and BPA interact in vivo, consistent with evidence that TBBPA and triclosan inhibit enzymes that are critical for BPA and E2 metabolism. https://doi.org/10.1289/EHP1329
Received: 04 November 2016
Revised: 11 April 2017
Accepted: 13 April 2017
Published: 21 August 2017
Address correspondence to D. deCatanzaro, Dept. of Psychology, Neuroscience & Behaviour, McMaster University, 1280 Main St. West, Hamilton ON L8S 4K1, Canada. Telephone: (905) 525-9140, ext. 23014. Email: decatanz@mcmaster.ca
Supplemental Material is available online (https://doi.org/10.1289/EHP...
Source: EHP Research - August 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Ambient Air Pollution and Cancer Mortality in the Cancer Prevention Study II
Conclusions:
The results from this large prospective study suggest that ambient air pollution was not associated with death from most nonlung cancers, but associations with kidney, bladder, and colorectal cancer death warrant further investigation. https://doi.org/10.1289/EHP1249
Received: 18 October 2016
Revised: 31 March 2017
Accepted: 31 March 2017
Published: 21 August 2017
Address correspondence to M.C. Turner, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, 600 Peter Morand Cres., Room 216, Ottawa, Ontario, Canada K1G 3Z7. Telephone: 613-562-5381. Email: mturner@uottawa.ca
Suppleme...
Source: EHP Research - August 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Personal Care Product Use in Men and Urinary Concentrations of Select Phthalate Metabolites and Parabens: Results from the Environment And Reproductive Health (EARTH) Study
Conclusions:
We identified 10 PCPs of relevance and demonstrated that their use within 6 h of urine collection strongly predicted MEP and paraben urinary concentrations. https://doi.org/10.1289/EHP1374
Received: 16 November 2016
Revised: 05 April 2017
Accepted: 06 April 2017
Published: 18 August 2017
Address correspondence to F.L. Nassan, Dept. of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Building 1, Room 1406, Boston, MA 02115 USA. Telephone: (857) 244-3312. Email: fen769@mail.harvard.edu
Supplemental Material is available online (https://doi.org/10.1289/EHP1374).
The auth...
Source: EHP Research - August 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Air Pollution and Risk of Parkinson ’s Disease in a Large Prospective Study of Men
Conclusions:
In this study, we found no evidence that exposure to air pollution is a risk factor for PD in men. https://doi.org/10.1289/EHP259
Received: 01 April 2016
Revised: 07 November 2016
Accepted: 10 November 2016
Published: 18 August 2017
Address correspondence to N. Palacios, Dept. of Public Health, University of Massachusetts, Lowell; Lowell, Massachusetts. Telephone: 617-304-4254. Email: natalia_palacios@uml.edu
Statistical analysis was done by N.P. and K.C.F.
The authors declare they have no actual or potential competing financial interests.
Note to readers with disabilities: EHP strives to ensure that...
Source: EHP Research - August 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Review of Epidemiological Studies of Drinking-Water Turbidity in Relation to Acute Gastrointestinal Illness
Conclusions:
The observed associations suggest a detectable incidence of waterborne AGI from drinking water in the systems and time periods studied. However, some discrepant results indicate that the association may be context specific. Combining turbidity with seasonal and climatic factors, additional water quality measures, and treatment data may enhance predictive modeling in future studies. https://doi.org/10.1289/EHP1090
Received: 12 September 2016
Revised: 24 February 2017
Accepted: 27 February 2017
Published: 17 August 2017
Address correspondence to A.J. De Roos, Nesbitt Hall, Room 658, 3215 Market St., Philad...
Source: EHP Research - August 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
Outdoor Light at Night and Breast Cancer Incidence in the Nurses ’ Health Study II
Conclusions:
Although further work is required to confirm our results and to clarify potential mechanisms, our findings suggest that exposure to residential outdoor light at night may contribute to invasive breast cancer risk. https://doi.org/10.1289/EHP935
Received: 08 August 2016
Revised: 17 March 2017
Accepted: 20 March 2017
Published: 17 August 2017
Address correspondence to P. James, 401 Park Dr., 3rd Floor West, Boston, MA 02215 USA. Telephone: (617) 525-2567; Email: pjames@hsph.harvard.edu
Supplemental Material is available online (https://doi.org/10.1289/EHP935).
The authors declare they have no actual or pot...
Source: EHP Research - August 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Adaptation to Climate Change: A Comparative Analysis of Modeling Methods for Heat-Related Mortality
Conclusions:
Researchers should carefully consider how to model adaptation because it is a source of uncertainty that can be greater than the uncertainty in emissions and climate modeling. We recommend absolute threshold shifts and reductions in slope. https://doi.org/10.1289/EHP634
Received: 09 June 2016
Revised: 15 September 2016
Accepted: 24 October 2016
Published: 16 August 2017
Address correspondence to S.N. Gosling, School of Geography, University of Nottingham, Nottingham NG7 2RD, UK. Telephone: +44(0)115 951 5437. Email: simon.gosling@nottingham.ac.uk
Supplemental Material is available online (https://doi.org...
Source: EHP Research - August 17, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Quantitative Microbial Risk Assessment for Spray Irrigation of Dairy Manure Based on an Empirical Fate and Transport Model
Conclusions:
Our model-based estimates suggest that reducing pathogen prevalence and concentration in source manure would reduce the risk of AGI from exposure to manure irrigation, and that increasing the distance from irrigated manure (i.e., setbacks) and limiting irrigation to times of low wind speed may also reduce risk. https://doi.org/10.1289/EHP283
Received: 30 March 2016
Revised: 07 March 2017
Accepted: 13 March 2017
Published: 16 August 2017
Address Correspondence to M.A. Borchardt, USDA-ARS, 2615 Yellowstone Dr., Marshfield, WI 54449 USA. Telephone: 715-387-4943. Email: Mark.Borchardt@ars.usda.gov
Supplement...
Source: EHP Research - August 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
New Rodent Population Models May Inform Human Health Risk Assessment and Identification of Genetic Susceptibility to Environmental Exposures
Conclusions:
These new resources offer substantial advances to classical toxicity testing paradigms by including genetically sensitive individuals that may inform toxicity risks for sensitive subpopulations. Both in vivo and complementary in vitro resources provide platforms with which to reduce uncertainty by providing population-level data around biological variability. https://doi.org/10.1289/EHP1274
Received: 25 October 2016
Revised: 19 April 2017
Accepted: 27 April 2017
Published: 15 August 2017
Address correspondence to K.A. McAllister, Program Administrator, Genes, Environment, and Health Branch, Division of E...
Source: EHP Research - August 15, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
Elemental Sulfur Use and Associations with Pediatric Lung Function and Respiratory Symptoms in an Agricultural Community (California, USA)
Conclusions:
This study suggests that elemental sulfur use, allowed in both organic and conventional farming, in close proximity to residential areas, may adversely affect children’s respiratory health. https://doi.org/10.1289/EHP528
Received: 19 May 2016
Revised: 05 May 2017
Accepted: 09 May 2017
Published: 14 August 2017
Address correspondence to R. Raanan, Center for Environmental Research and Children’s Health (CERCH), University of California, Berkeley, School of Public Health, 1995 University Ave., Suite 265, Berkeley, CA 94704 USA. Telephone: (510) 642-9431. Email: rachelraananrr@gmail.com
Supplemental Ma...
Source: EHP Research - August 14, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Heat Wave and Mortality: A Multicountry, Multicommunity Study
Conclusions:
Results indicate that high temperatures create a substantial health burden, and effects of high temperatures over consecutive days are similar to what would be experienced if high temperature days occurred independently. People living in moderate cold and moderate hot areas are more sensitive to heat waves than those living in cold and hot areas. Daily mean and maximum temperatures had similar ability to define heat waves rather than minimum temperature. https://doi.org/10.1289/EHP1026
Received: 26 August 2016
Revised: 20 March 2017
Accepted: 31 March 2017
Published: 14 August 2017
Address correspondence...
Source: EHP Research - August 14, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Detecting and Attributing Health Burdens to Climate Change
Conclusions:
The results of detection and attribution studies can inform evidence-based risk management to reduce current, and plan for future, changes in health risks associated with climate change. Gaining a better understanding of the size, timing, and distribution of the climate change burden of disease and injury requires reliable long-term data sets, more knowledge about the factors that confound and modify the effects of climate on health, and refinement of analytic techniques for detection and attribution. At the same time, significant advances are possible in the absence of complete data and statistical certainty:...
Source: EHP Research - August 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
Developing the Regulatory Utility of the Exposome: Mapping Exposures for Risk Assessment through Lifestage Exposome Snapshots (LEnS)
Conclusions:
The LEnS concept is a practical refinement to the exposome that accounts for total exposures during particular windows of susceptibility in target organ systems. Application of the LEnS framework in risk assessment and regulation will improve protection of children’s health by enhancing protection of sensitive developing organ systems that are critical for lifelong health and well-being. https://doi.org/10.1289/EHP1250
Received: 19 October 2016
Revised: 08 March 2017
Accepted: 04 April 2017
Published: 07 August 2017
Please address correspondence to E.M. Faustman, Dept. of Environmental and Occupational...
Source: EHP Research - August 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
