Prenatal Exposure to Nonpersistent Endocrine Disruptors and Behavior in Boys at 3 and 5 Years
Conclusions:
The observed associations between BPA, MnBP, and behavior in boys are consistent with previous findings. Further health impact assessment studies based on dose–response functions corrected for exposure misclassification are required to quantify the public health burden possibly entailed by such associations. https://doi.org/10.1289/EHP1314
Received: 02 November 2016
Revised: 23 May 2017
Accepted: 19 June 2017
Published: 15 September 2017
Address correspondence to C. Philippat, Institut for Advanced Biosciences, Site Santé – Allée des Alpes, 38700 La Tronche, France. Phone: +33 4 76 54 94 66, Email:...
Source: EHP Research - September 15, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Adipogenic Effects and Gene Expression Profiling of Firemaster ® 550 Components in Human Primary Preadipocytes
Conclusions:
We found that FM550, and two of its components, induced adipogenesis in human primary preadipocytes. Further, using global gene expression analysis we showed that both TPP and IPTP likely exert their effects through PPARG to induce adipogenesis. In addition, IPTP perturbed signaling pathways that were not affected by TPP. https://doi.org/10.1289/EHP1318
Received: 02 November 2016
Revised: 18 May 2017
Accepted: 23 May 2017
Published: 14 September 2017
Address correspondence to E. Atlas, Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ottawa, Ontario, K1A 0K9, Canada...
Source: EHP Research - September 15, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Changes in Transportation-Related Air Pollution Exposures by Race-Ethnicity and Socioeconomic Status: Outdoor Nitrogen Dioxide in the United States in 2000 and 2010
Conclusions:
Findings suggest that absolute NO2 exposure disparities by race-ethnicity decreased from 2000 to 2010, but relative NO2 exposure disparities persisted, with higher NO2 concentrations for nonwhites than whites in 2010. https://doi.org/10.1289/EHP959
Received: 15 August 2016
Revised: 07 June 2017
Accepted: 09 June 2017
Published: 14 September 2017
Please address correspondence to J.D. Marshall, Dept. of Civil, Environmental, and Geo-Engineering, University of Washington, 201 More Hall, Seattle, WA 98195 USA. Telephone: (206) 685-2591. Email: jdmarsh@uw.edu
Supplemental Material is available online (https:/...
Source: EHP Research - September 15, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization
Conclusions:
Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685
Received: 19 June 2016
Revised: 07 June 2017
Accepted: 19 June 2017
Published: 13 September 2017
Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Randomized Trial of Interventions to Improve Childhood Asthma in Homes with Wood-burning Stoves
Conclusions:
Among children with asthma and chronic exposure to woodsmoke, an air-filter intervention that improved indoor air quality did not affect quality-of-life measures. Intent-to-treat analysis did show an improvement in the secondary measure of dPFV.
Trial registration:
ClincialTrials.gov NCT00807183. https://doi.org/10.1289/EHP849
Received: 21 July 2016
Revised: 13 June 2017
Accepted: 16 June 2017
Published: 13 September 2017
Address correspondence to C.W. Noonan, School of Public and Community Health Sciences, 32 Campus Dr., University of Montana, Missoula, MT 59812 USA. Telephone: (406) 243-4957; Fax: (406...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Children ’s Lead Exposure: A Multimedia Modeling Analysis to Guide Public Health Decision-Making
Conclusions:
This methodology advances scientific understanding of the relationship between lead concentrations in drinking water and BLLs in children. It can guide national health-based benchmarks for lead and related community public health decisions. https://doi.org/10.1289/EHP1605
Received: 12 January 2017
Revised: 09 May 2017
Accepted: 18 May 2017
Published: 12 September 2017
Address correspondence to V. Zartarian, 5 Post Office Square, Suite 100, MC ORA 01-3, Boston, MA 02109-3912 USA. Telephone: (617) 918-1541. Email: zartarian.valerie@epa.gov
Supplemental Material is available online (https://doi.org/10.1289/...
Source: EHP Research - September 12, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Scientific Challenges in the Risk Assessment of Food Contact Materials
Conclusion:
We think that exposures to hazardous substances migrating from FCAs require more attention. We recommend a) limiting the number and types of chemicals authorized for manufacture and b) developing novel approaches for assessing the safety of chemicals in FCAs, including unidentified chemicals that form during or after production. https://doi.org/10.1289/EHP644
Received: 10 June 2016
Revised: 08 June 2017
Accepted: 09 June 2017
Published: 11 September 2017
Address correspondence to J. Muncke, Food Packaging Forum, Staffelstrasse 8, 8045 Zurich, Switzerland. Telephone: 41-44-5155255. Email: jane.muncke@fp-fo...
Source: EHP Research - September 11, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
Early-Life Phthalate Exposure and Adiposity at 8 Years of Age
Conclusion:
In this cohort, we did not find evidence of an obesogenic effect of prenatal phthalate exposure. Positive associations between postnatal MEP and ∑DEHP concentrations depended on the timing of exposure. https://doi.org/10.1289/EHP1022
Received: 29 August 2016
Revised: 17 February 2017
Accepted: 28 February 2017
Published: 11 September 2017
Address Correspondence to J.R. Shoaff, Brown University School of Public Health, Box G-S121-2, Providence, RI 02912 USA. Email: jessica_shoaff@brown.edu
Supplemental Material is available online (https://doi.org/10.1289/EHP1022).
The authors declare they have no actual...
Source: EHP Research - September 11, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Combined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism Spectrum Disorder
Conclusions:
In this study population, associations between pesticide exposures and ASD were attenuated among those with high versus low FA intake during the first month of pregnancy. Confirmatory and mechanistic studies are needed. https://doi.org/10.1289/EHP604
Received: 07 June 2016
Revised: 16 March 2017
Accepted: 18 March 2017
Published: 08 September 2017
Address correspondence to R. J. Schmidt, 123 Medical Sciences 1C, One Shields Ave., Davis, CA 95616-8638 USA; Telephone: (530) 752-3226. Email: rjschmidt@ucdavis.edu
*Current address: Department of Mental Health, Wendy Klag Center for Autism and Developmental D...
Source: EHP Research - September 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
In Utero Exposure to Select Phenols and Phthalates and Respiratory Health in Five-Year-Old Boys: A Prospective Study
Conclusion:
Ethyl-paraben, bisphenol A, 2,5-dichlorophenol, and DIDP tended to be associated with altered respiratory health, with ethyl-paraben and bisphenol A exhibiting some consistency across respiratory outcomes. The trends between bisphenol A pregnancy level and increased asthma and bronchiolitis/bronchitis rates in childhood were consistent with a previous cohort study. https://doi.org/10.1289/EHP1015
Received: 25 August 2016
Revised: 12 January 2017
Accepted: 26 January 2017
Published: 08 September 2017
Address correspondence to C. Vernet, Institute for Advanced Biosciences (IAB), Centre de Recherche INSERMâ€...
Source: EHP Research - September 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Rice Consumption and Squamous Cell Carcinoma of the Skin in a United States Population
Conclusion:
Rice consumption may be related to the occurrence of SCC in the United States, especially among those with relatively low drinking water arsenic exposure. https://doi.org/10.1289/EHP1065
Received: 06 September 2016
Revised: 04 July 2017
Accepted: 06 July 2017
Published: 07 September 2017
Address correspondence to M.R. Karagas, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756 USA. Telephone: (603) 653-9010. Email: Margaret.R.Karagas@dartmouth.edu
Supplemental Material is available online (https://doi.org/10.1289/EHP1065).
The authors declare they have no actual ...
Source: EHP Research - September 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Exposure to Road, Railway, and Aircraft Noise and Arterial Stiffness in the SAPALDIA Study: Annual Average Noise Levels and Temporal Noise Characteristics
Conclusions:
Long-term exposure to railway noise, particularly in an intermittent nighttime noise environment, and to nighttime noise events, mainly related to road noise, may affect arterial stiffness, a major determinant of cardiovascular disease. Ascertaining noise exposure characteristics beyond average noise levels may be relevant to better understand noise-related health effects. https://doi.org/10.1289/EHP1136
Received: 23 September 2016
Revised: 20 March 2017
Accepted: 31 March 2017
Published: 07 September 2017
Address correspondence to M. Foraster, Swiss Tropical and Public Health Institute, Dept. of Epidemi...
Source: EHP Research - September 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Estimated Changes in Life Expectancy and Adult Mortality Resulting from Declining PM2.5 Exposures in the Contiguous United States: 1980 –2010
Conclusions:
Our estimates suggest that declines in PM2.5 exposures between 1980 and 2010 have benefitted public health. https://doi.org/10.1289/EHP507
Received: 13 May 2016
Revised: 19 June 2017
Accepted: 20 June 2017
Published: 06 September 2017
Address correspondence to N. Fann, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Mail drop C539-07; RTP, NC 27711 USA. Phone: (919) 541-0209. Email: Fann.neal@epa.gov
Supplemental Material is available online (https://doi.org/10.1289/EHP507).
The authors declare they have no actual or potential competing financial interests.
The views in this manuscript are ...
Source: EHP Research - September 6, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Insecticide Use and Breast Cancer Risk among Farmers ’ Wives in the Agricultural Health Study
Conclusion:
Use of several organophosphate insecticides was associated with elevated breast cancer risk. However, associations for the women’s and husbands’ use of these insecticides showed limited concordance. Ongoing cohort follow-up may help clarify the relationship, if any, between individual insecticide exposures and breast cancer risk. https://doi.org/10.1289/EHP1295
Received: 28 October 2016
Revised: 25 April 2017
Accepted: 08 May 2017
Published: 06 September 2017
Address correspondence to L. Engel, Dept. of Epidemiology, University of North Carolina, CB #7435, Chapel Hill, NC 27599-7435 USA. Telephone: 91...
Source: EHP Research - September 6, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Application of Adverse Outcome Pathways to U.S. EPA ’s Endocrine Disruptor Screening Program
Conclusions:
A variety of biological systems affect apical end points used in regulatory risk assessments, and without mechanistic data, an endocrine mode of action cannot be determined. Because the EDSP was designed to consider mode of action, toxicity pathway and AOP concepts are a natural fit. Pathway frameworks have diverse applications to endocrine screening and testing. An estrogen pathway example is presented, and similar approaches are being used to evaluate alternative methods and develop predictive models for androgen and thyroid pathways. https://doi.org/10.1289/EHP1304
Received: 31 October 2016
Revised: 13 ...
Source: EHP Research - September 1, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
