Effects of Prenatal PM10 Exposure on Fetal Cardiovascular Malformations in Fuzhou, China: A Retrospective Case-Control Study
Conclusions: Our findings suggest some positive associations between maternal exposure to ambient PM10 during the first two months of pregnancy and fetal cardiovascular malformations. https://doi.org/10.1289/EHP289 Received: 8 December 2015 Revised: 30 May 2016 Accepted: 17 June 2016 Published: 25 May 2017 Address correspondence to X.-R. Hong, Department of Obstetrics and Gynecology, Fuzhou General Hospital, 156 North Xihuan Rd., Fuzhou 350025, Fujian, China. Telephone: +86-591-2285-9200. E-mail: hxr0812@163.com or to X.-Q. Chen, Fujian Central Station of Environmental Monitoring, 138 South Fufei Rd., Fuzhou 350003, Fu...
Source: EHP Research - May 26, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

Manganese in Drinking Water and Cognitive Abilities and Behavior at 10 Years of Age: A Prospective Cohort Study
Author Affiliations open 1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden 2International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh 3Center of Neurodevelopmental Disorders (KIND), Pediatric Neuropsychiatry Unit, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden 4Center for Psychiatry Research, Stockholm County Council, Stockholm, Sweden PDF Version (191 KB) Abstract About This Article Supplemental Material Background: Cross-sectional studies have indicated impaired neurodevelopment with elevated...
Source: EHP Research - May 26, 2017 Category: Environmental Health Authors: Terrie Young Tags: Research Source Type: research

An Integrated Chemical Environment to Support 21st-Century Toxicology
Author Affiliations open 1Integrated Laboratory Systems, Inc. (ILS), Research Triangle Park, North Carolina, USA; 2Sciome, Research Triangle Park, North Carolina, USA; 3Program Operations Branch, National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA; 4NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, NTP, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA PDF Version (277 KB) Abstract About This Article ...
Source: EHP Research - May 25, 2017 Category: Environmental Health Authors: Terrie Young Tags: Brief Communication Source Type: research

Retraction: “A Case-Cohort Study of Cadmium Body Burden and Gestational Diabetes Mellitus in American Women”
This article is being retracted at the request of the authors because of inadvertent errors in the statistical code that resulted in the exclusion of 12 gestational diabetes mellitus cases with urinary cadmium below the limit of detection. The coding errors do not impact any other published studies of this population. In Table 1, the corrected geometric mean for the gestational diabetes mellitus cases was 0.33 μg/g Cr [95% confidence interval (CI): 0.30, 0.37]. In Table 2, the magnitude of the effect estimates reported was attenuated and the p-trend was no longer statistically significant, such that the odds ratios for ...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: Perspectives Retraction April 2017 Source Type: research

Erratum: “Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study”
About This Article open Citation: Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro A, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. 2017. Erratum: “Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study.” Environ Health Perspect 125:A63; http://dx.doi.org/10.1289/EHP1813 Final Publication: 31 March 2017 PDF Version (58 KB) Related EHP Article Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study Elena Colicino...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: Perspectives Erratum April 2017 Source Type: research

Erratum: “Microcystis Rising: Why Phosphorus Reduction Isn’t Enough to Stop CyanoHABs”
About This Article open Citation: Levy S. 2017. Erratum: “Microcystis Rising: Why Phosphorus Reduction Isn’t Enough to Stop CyanoHABs.” Environ Health Perspect 125:A62; http://dx.doi.org/10.1289/EHP1787 Final Publication: 31 March 2017 PDF Version (50 KB) Related EHP Article Microcystis Rising: Why Phosphorus Reduction Isn’t Enough to Stop CyanoHABs Sharon Levy Environ Health Perspect 125(2):A34–A39 (2017), http://dx.doi.org/10.1289/ehp.125-A34 One of the researchers quoted in this article was not fully identified. Timothy Davis is a research scientist at the Great Lakes En...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: Perspectives Erratum April 2017 Source Type: research

The Forest and the Trees: How Population-Level Health Protections Sometimes Fail the Individual
Burdening individuals with the responsibility of reducing their own environmental exposures is not only unreliable in terms of health protection but also a contributor to environmental injustice.© Raga/Getty Images These photos show the air quality in Beijing on 1 January 2017 (top) in the midst of an “airpocalypse” smog emergency and on a clear day the week before. The notoriously bad air in many Chinese cities is slowly improving overall, but long-term exposures are still many times higher than World Health Organization recommendations.© Greg Baker/AFP/Getty Images  ...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: News Focus April 2017 Source Type: research

Way to Go: Identifying Routes for Walkers and Cyclists to Avoid Air Pollutants
Carol Potera, based in Montana, also writes for Microbe, Genetic Engineering News, and the American Journal of Nursing. About This Article open Citation: Potera C. 2017. Way to go: identifying routes for walkers and cyclists to avoid air pollutants. Environ Health Perspect 125:A71; http://dx.doi.org/10.1289/ehp.125-A71 Published: 31 March 2017 PDF Version (2.1 MB) Related EHP Article Population-Level Exposure to Particulate Air Pollution during Active Travel: Planning for Low-Exposure, Health-Promoting Cities Steve Hankey, Greg Lindsey, and Julian D. Marshall Exposures to air pollutants may offset a p...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: News Science Selections April 2017 Source Type: research

A Satellite –Ground Hybrid Approach: Relative Risks for Exposures to PM2.5 Estimated from a Combination of Data Sources
Nate Seltenrich covers science and the environment from Petaluma, CA. His work has appeared in High Country News, Sierra, Yale Environment 360, Earth Island Journal, and other regional and national publications. About This Article open Citation: Seltenrich N. 2017. A satellite–ground hybrid approach: relative risks for exposures to PM2.5 estimated from a combination of data sources. Environ Health Perspect 125:A73; http://dx.doi.org/10.1289/ehp.125-A73 Published: 31 March 2017 PDF Version (360 KB) Related EHP Article Comparing the Health Effects of Ambient Particulate Matter Estimated Using Ground-B...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: News Science Selections April 2017 Source Type: research

A Blend of Old and New: Biomonitoring Methods to Study the Exposome
Rachel Cernansky is a freelance journalist in Denver, Colorado, covering science, health, and the environment. She has written for publications including Yale Environment 360, Nature, Civil Eats, and The New York Times. About This Article open Citation: Cernansky R. 2017. A blend of old and new: biomonitoring methods to study the exposome. Environ Health Perspect 125:A74; http://dx.doi.org/10.1289/ehp.125-A74 Published: 31 March 2017 PDF Version (502 KB) Related EHP Article Biomonitoring in the Era of the Exposome Kristine K. Dennis, Elizabeth Marder, David M. Balshaw, Yuxia Cui, Michael A. Lynes, Gary J....
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: News Science Selections April 2017 Source Type: research

Programming the Future: Epigenetics in the Context of DOHaD
Julia R. Barrett, MS, ELS, a Madison, WI–based science writer and editor, is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences. About This Article open Citation: Barrett JR. 2017. Programming the future: epigenetics in the context of DOHaD. Environ Health Perspect 125:A72; http://dx.doi.org/10.1289/ehp.125-A72 Published: 31 March 2017 PDF Version (191 KB) Related EHP Article Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children’s Environmental Health Studies: The Children’s Environmental Health and Disease ...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: News Science Selections April 2017 Source Type: research

The Emergence of Environmental Health Literacy —From Its Roots to Its Future Potential
Conclusions: We posit that EHL can potentially benefit the conduct and outcomes of community-engaged and health disparities EHS research and can ensure that the translation of research findings will lead to greater understanding of specific risks, reduction of exposures, and improvement of health outcomes for individuals and communities. We provide four recommendations to advance work in EHL. Citation: Finn S, O’Fallon L. 2017. The emergence of environmental health literacy—from its roots to its future potential. Environ Health Perspect 125:495–501; http://dx.doi.org/10.1289/ehp.1409337 Address correspo...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries April 2017 Source Type: research

Biomonitoring in the Era of the Exposome
Conclusions: To understand the complexity of exposures faced throughout the lifespan, both traditional and nontraditional biomonitoring methods should be used. Through hybrid approaches and the integration of emerging techniques, biomonitoring strategies can be maximized in research to define the exposome. Citation: Dennis KK, Marder E, Balshaw DM, Cui Y, Lynes MA, Patti GJ, Rappaport SM, Shaughnessy DT, Vrijheid M, Barr DB. 2017. Biomonitoring in the era of the exposome. Environ Health Perspect 125:502–510; http://dx.doi.org/10.1289/EHP474 Address correspondence to D.B. Barr, Department of Environmental Health, Ro...
Source: EHP Research - March 31, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries April 2017 Source Type: research

Climate and Health Co-Benefits in Low-Income Countries: A Case Study of Carbon Financed Water Filters in Kenya and a Call for Independent Monitoring
Conclusion: Independent monitoring should be a key requirement for carbon credit verification in future international carbon trading mechanisms to ensure programs achieve benefits in line with sustainable development goals. Citation: Pickering AJ, Arnold BF, Dentz HN, Colford JM Jr., Null C. 2017. Climate and health co-benefits in low-income countries: a case study of carbon financed water filters in Kenya and a call for independent monitoring. Environ Health Perspect 125:278–283; http://dx.doi.org/10.1289/EHP342 Address correspondence to A.J. Pickering, Civil and Environmental Engineering, 473 Via Ortega, Y2E2 Bui...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries March 2017 Source Type: research

Health Risk Assessment of Dietary Cadmium Intake: Do Current Guidelines Indicate How Much is Safe?
Conclusion Current population risk assessment of dietary Cd intake relies on estimates of dietary Cd intake and/or maintenance of threshold levels of urinary Cd that should protect the kidney from Cd-induced damage. Risk assessment using dietary Cd intake estimates has been questioned because they show only a marginal correlation with urinary Cd levels, a well-founded measure of lifetime intakes. Blood Cd levels, however, show a correlation with urinary Cd levels, and they could thus be of value in risk assessment; blood Cd levels ≥ 1 μg/L were associated with CKD, while blood Cd levels above 0.5 μg/L were associa...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries March 2017 Source Type: research

An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays
Conclusion: This integrated study design is efficient in that the same generational cohort of rats used for evaluating long-term outcomes can be monitored in satellite parallel experiments to measure biomarkers and other parameters related to system-specific responses including metabolic alterations and endocrine disturbances. Citation: Manservisi F, Babot Marquillas C, Buscaroli A, Huff J, Lauriola M, Mandrioli D, Manservigi M, Panzacchi S, Silbergeld EK, Belpoggi F. 2017. An integrated experimental design for the assessment of multiple toxicological end points in rat bioassays. Environ Health Perspect 125:289–295...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries March 2017 Source Type: research

Relative Contributions of Agricultural Drift, Para-Occupational, and Residential Use Exposure Pathways to House Dust Pesticide Concentrations: Meta-Regression of Published Data
Conclusion: Our quantification of the relative contributions of pesticide exposure pathways in agricultural populations could improve exposure assessments in epidemiologic studies. The meta-regression models can be updated when additional data become available. Citation: Deziel NC, Beane Freeman LE, Graubard BI, Jones RR, Hoppin JA, Thomas K, Hines CJ, Blair A, Sandler DP, Chen H, Lubin JH, Andreotti G, Alavanja MC, Friesen MC. 2017. Relative contributions of agricultural drift, para-occupational, and residential use exposure pathways to house dust pesticide concentrations: meta-regression of published data. Environ Heal...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Reviews March 2017 Source Type: research

Biomarker Levels of Toxic Metals among Asian Populations in the United States: NHANES 2011 –2012
Author Affiliations open 1University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA; 2CH2M HILL, Inc., Houston, Texas, USA PDF Version (188 KB) Abstract About This Article Supplemental Material Introduction: The Centers for Disease Control and Prevention (CDC) recently found that Asians have considerably higher biomarker levels of cadmium, lead, mercury, and arsenic than whites, blacks, Mexican Americans, and other Hispanics in the United States. Objective: Our goal was to further evaluate the higher metal biomarker levels among Asians. Methods: Biomarker data (blood cadm...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles Children's Health March 2017 Source Type: research

Association of Dietary Intake and Biomarker Levels of Arsenic, Cadmium, Lead, and Mercury among Asian Populations in the United States: NHANES 2011 –2012
Author Affiliations open 1University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA; 2CH2M HILL, Inc., Houston, Texas, USA PDF Version (1.1 MB) Abstract About This Article Supplemental Material Background: We have recently shown that biomarker levels of selected metals are higher in Asians than in other U.S. ethnic groups, with important differences within selected Asian subgroups. Much of this difference may be dietary in origin; however, this is not well established. Objective: We evaluated dietary intake of toxic metals as a source of increased biomarker levels of meta...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles Children's Health March 2017 Source Type: research

Passive Sampling for Indoor and Outdoor Exposures to Chlorpyrifos, Azinphos-Methyl, and Oxygen Analogs in a Rural Agricultural Community
Conclusions: We identified higher levels in air and on surfaces at both proximal and farmworker households. Our findings further confirm the presence of pesticides and their oxygen analogs in air and highlight their potential for infiltration of indoor living environments. Citation: Gibbs JL, Yost MG, Negrete M, Fenske RA. 2017. Passive sampling for indoor and outdoor exposures to chlorpyrifos, azinphos-methyl, and oxygen analogs in a rural agricultural community. Environ Health Perspect 125:333–341; http://dx.doi.org/10.1289/EHP425 Address correspondence to J.L. Gibbs, Department of Occupational and Environmental ...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles March 2017 Source Type: research

Estimating State-Specific Contributions to PM2.5 ‐ and O3-Related Health Burden from Residential Combustion and Electricity Generating Unit Emissions in the United States
Conclusions: Our findings reinforce the importance of pollutant-specific, location-specific, and source-specific models of health impacts in design of health-risk minimizing emissions control policies. Citation: Penn SL, Arunachalam S, Woody M, Heiger-Bernays W, Tripodis Y, Levy JI. 2017. Estimating state-specific contributions to PM2.5‐ and O3-related health burden from residential combustion and electricity generating unit emissions in the United States. Environ Health Perspect 125:324–332; http://dx.doi.org/10.1289/EHP550 Address correspondence to S.L. Penn, Boston University School of Public Health, Departmen...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles March 2017 Source Type: research

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study
Conclusion: PM2.5 was associated with depressive and anxiety symptoms, with associations the strongest among individuals with lower SES or among those with certain health-related characteristics. Citation: Pun VC, Manjourides J, Suh H. 2017. Association of ambient air pollution with depressive and anxiety symptoms in older adults: results from the NSHAP study. Environ Health Perspect 125:342–348; http://dx.doi.org/10.1289/EHP494 Address correspondence to H. Suh, Department of Civil and Environmental Engineering, Tufts University, Medford, MA 02153 USA. Telephone: (617) 627-2941. Email: Helen.Suh@tufts.edu We ack...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles March 2017 Source Type: research

Air Pollution and Deaths among Elderly Residents of S ão Paulo, Brazil: An Analysis of Mortality Displacement
Conclusions: We found evidence of mortality displacement within 30 days for nonaccidental and circulatory deaths in elderly residents of São Paulo. We did not find evidence of mortality displacement within 30 days for respiratory or cancer deaths. Citation: Costa AF, Hoek G, Brunekreef B, Ponce de Leon AC. 2017. Air pollution and deaths among elderly residents of São Paulo, Brazil: an analysis of mortality displacement. Environ Health Perspect 125:349–354; http://dx.doi.org/10.1289/EHP98 Address correspondence to A.F. Costa, Rua Equador 831, Rio de Janeiro, RJ, Brazil, 20220-410. Telephone: 5521320728...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles March 2017 Source Type: research

Multiple Threats to Child Health from Fossil Fuel Combustion: Impacts of Air Pollution and Climate Change
Conclusion: Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141–148; http://dx.doi.org/10.1289/EHP299 Address correspondence to F.P. Perera, Department of Environmental Health Sciences, Columbia Center for Children’s Environmental Health, Columbia University Mailman School of Public Health, 722 West 168th St. ...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries Children's Health February 2017 Source Type: research

The Case for “Environment in All Policies”: Lessons from the “Health in All Policies” Approach in Public Health
Conclusions: We encourage further exploration of the feasibility of EiAP as an approach that could make explicit the sometimes surprising environmental implications of a whole range of strategic policies. Citation: Browne GR, Rutherfurd ID. 2017. The case for “environment in all policies”: lessons from the “health in all policies” approach in public health. Environ Health Perspect 125:149–154; http://dx.doi.org/10.1289/EHP294 Address correspondence to G.R. Browne, McCaughey VicHealth Centre for Community Wellbeing, Centre for Health Equity, School of Population and Global Health, The Univers...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries February 2017 Source Type: research

Effects of Neonicotinoid Pesticide Exposure on Human Health: A Systematic Review
Conclusions: The studies conducted to date were limited in number with suggestive but methodologically weak findings related to chronic exposure. Given the wide-scale use of neonics, more studies are needed to fully understand their effects on human health. Citation: Cimino AM, Boyles AL, Thayer KA, Perry MJ. 2017. Effects of neonicotinoid pesticide exposure on human health: a systematic review. Environ Health Perspect 125:155–162; http://dx.doi.org/10.1289/EHP515 Address correspondence to M.J. Perry, Department of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington Un...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Reviews February 2017 Source Type: research

Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations
Conclusions: The theoretical merits of the low-dose carcinogenesis hypothesis are well founded with clear biological relevance, and therefore, the premise warrants further investigation. Expert recommendations include the need for better insights into the ways in which noncarcinogenic constituents might combine to uniquely affect the process of cellular transformation (in vitro) and environmental carcinogenesis (in vivo), including investigations of the role of key defense mechanisms in maintaining transformed cells in a dormant state. The scientific community will need to acknowledge limitations of animal-based models in ...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Reviews February 2017 Source Type: research

The Prevalence and Use of Walking Loops in Neighborhood Parks: A National Study
Conclusions: Walking loops may be a promising means of increasing population level physical activity. Further studies are needed to confirm a causal relationship. Citation: Cohen DA, Han B, Evenson KR, Nagel C, McKenzie TL, Marsh T, Williamson S, Harnik P. 2017. The prevalence and use of walking loops in neighborhood parks: a national study. Environ Health Perspect 125:170–174; http://dx.doi.org/10.1289/EHP293 Address correspondence to D.A. Cohen, RAND Corporation, 1776 Main St., Santa Monica, CA 90407 USA. Telephone: (310) 393-0411, ext 6023. E-mail: dcohen@rand.org This study was funded by the National Heart, Lun...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Cardiovascular Benefits of Wearing Particulate-Filtering Respirators: A Randomized Crossover Trial
Conclusions: Short-term wearing of particulate-filtering respirators may produce cardiovascular benefits by improving autonomic nervous function and reducing BP. Citation: Shi J, Lin Z, Chen R, Wang C, Yang C, Cai J, Lin J, Xu X, Ross JA, Zhao Z, Kan H. 2017. Cardiovascular benefits of wearing particulate-filtering respirators: a randomized crossover trial. Environ Health Perspect 125:175–180; http://dx.doi.org/10.1289/EHP73 Address correspondence to H. Kan, Department of Environmental Health, School of Public Health, Fudan University, P.O. Box 249, 130 Dong-An Rd., Shanghai 200032, China. Telephone: 86 (21) 5423 7...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Evaluating the Impact of the U.S. National Toxicology Program: A Case Study on Hexavalent Chromium
Conclusions: This study identified a broad and objective approach for assessing NTP’s effectiveness, including methodological needs for more thorough and efficient impact assessments in the future. Citation: Xie Y, Holmgren S, Andrews DMK, Wolfe MS. 2017. Evaluating the impact of the U.S. National Toxicology Program: a case study on hexavalent chromium. Environ Health Perspect 125:181–188; http://dx.doi.org/10.1289/EHP21 Address correspondence to Y. Xie, National Institute of Environmental Health Sciences, P.O. Box 12233, Mail Drop K2-03, Research Triangle Park, NC 27709 USA. Express mail address: 530 Davis D...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Associations between Unconventional Natural Gas Development and Nasal and Sinus, Migraine Headache, and Fatigue Symptoms in Pennsylvania
Conclusions: This study provides evidence that UNGD is associated with nasal and sinus, migraine headache, and fatigue symptoms in a general population representative sample. Citation: Tustin AW, Hirsch AG, Rasmussen SG, Casey JA, Bandeen-Roche K, Schwartz BS. 2017. Associations between unconventional natural gas development and nasal and sinus, migraine headache, and fatigue symptoms in Pennsylvania. Environ Health Perspect 125:189–197; http://dx.doi.org/10.1289/EHP281 Address correspondence to B.S. Schwartz, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., Room W7041, Baltimore, MD 21205 USA. Te...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Sex-Specific Effects of Organophosphate Diazinon on the Gut Microbiome and Its Metabolic Functions
Conclusions: Diazinon exposure perturbed the gut microbiome community structure, functional metagenome, and associated metabolic profiles in a sex-specific manner. These findings may provide novel insights regarding perturbations of the gut microbiome and its functions as a potential new mechanism contributing to diazinon neurotoxicity and, in particular, its sex-selective effects. Citation: Gao B, Bian X, Mahbub R, Lu K. 2017. Sex-specific effects of organophosphate diazinon on the gut microbiome and its metabolic functions. Environ Health Perspect 125:198–206; http://dx.doi.org/10.1289/EHP202 Address corresponden...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Genes Interacting with Occupational Exposures to Low Molecular Weight Agents and Irritants on Adult-Onset Asthma in Three European Studies
Author Affiliations open 1Inserm, U1168, VIMA: Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Villejuif, France; 2Spanish National Cancer Research Centre (CNIO), Genetic and Molecular Epidemiology Group, Human Cancer Genetics Program, Madrid, Spain; 3Inserm UMR 1181 [Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases (B2PHI)], Villejuif, France; 4Institut Pasteur, UMR 1181, B2PHI, Paris, France; 5Univ Versailles St.-Quentin-en-Yvelines, UMR 1181, B2PHI, Montigny le Bretonneux, France; 6ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spai...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles February 2017 Source Type: research

Erratum: “Para– and Ortho-Substitutions Are Key Determinants of Polybrominated Diphenyl Ether Activity toward Ryanodine Receptors and Neurotoxicity”
About This Article open Citation: Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. 2012. Erratum: “Para– and Ortho-Substitutions Are Key Determinants of Polybrominated Diphenyl Ether Activity toward Ryanodine Receptors and Neurotoxicity.” Environ Health Perspect 120:A189; http://dx.doi.org/10.1289/ehp.120-A189 Final Publication: 1 May 2012   Related EHP Article Para– and Ortho-Substitutions Are Key Determinants of Polybrominated Diphenyl Ether Activity toward Ryanodine Receptors and Neurotoxicity Kyung Ho Kim, Diptiman D. Bose, Atefeh Ghogha, Joyce Riehl, Rui...
Source: EHP Research - January 23, 2017 Category: Environmental Health Authors: Sam Duvall Tags: Perspectives Erratum May 2012 Source Type: research

Errata: “Temporal Variability of Tungsten and Cobalt in Fallon, Nevada” & “A Retrospective Assessment of Occupational Exposure to Elemental Carbon in the U.S. Trucking Industry”
Discussion”), there was a coding error in the original calculation: The percentage of person-years prior to 1971 was 8% and not 1.1%, as stated in the article. The authors apologize for the error. This error has been corrected in the PDF version of this article. (Source: EHP Research)
Source: EHP Research - January 23, 2017 Category: Environmental Health Authors: Sam Duvall Tags: Perspectives Erratum February 2012 Source Type: research

Erratum: “A Retrospective Assessment of Occupational Exposure to Elemental Carbon in the U.S. Trucking Industry”
Discussion”), there was a coding error in the original calculation: The percentage of person-years prior to 1971 was 8% and not 1.1%, as stated in the article. The authors apologize for the error. This error has been corrected in the PDF version of this article. (Source: EHP Research)
Source: EHP Research - January 23, 2017 Category: Environmental Health Authors: Sam Duvall Tags: Perspectives Erratum February 2012 Source Type: research

Colorectal Cancer and Long-Term Exposure to Trihalomethanes in Drinking Water: A Multicenter Case –Control Study in Spain and Italy
Conclusions: We did not find clear evidence of an association between detailed estimates of lifetime total THM exposure and colorectal cancer in our large case–control study population. Negative associations with chloroform concentrations and ingestion suggest differences among specific THMs, but these findings should be confirmed in other study populations. Citation: Villanueva CM, Gracia-Lavedan E, Bosetti C, Righi E, Molina AJ, Martín V, Boldo E, Aragonés N, Perez-Gomez B, Pollan M, Gomez Acebo I, Altzibar JM, Jiménez Zabala A, Ardanaz E, Peiró R, Tardón A, Chirlaque MD, Tavani...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice
Conclusion: In utero exposure to environmental mutagens contributes to somatic and germline mosaicism, permanently affecting both the genetic health of the F1 and the population gene pool. Citation: Meier MJ, O’Brien JM, Beal MA, Allan B, Yauk CL, Marchetti F. 2017. In utero exposure to benzo[a]pyrene increases mutation burden in the soma and sperm of adult mice. Environ Health Perspect 125:82–88; http://dx.doi.org/10.1289/EHP211 *These authors contributed equally to this work. Address correspondence to F. Marchetti, Environmental Health Science and Research Bureau, Health Canada, 50 Colombine Driveway, Ot...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

Urban and Transport Planning Related Exposures and Mortality: A Health Impact Assessment for Cities
Conclusions: PA factors and environmental exposures can be modified by changes in urban and transport planning. We emphasize the need for a) the reduction of motorized traffic through the promotion of active and public transport and b) the provision of green infrastructure, both of which are suggested to provide opportunities for PA and for mitigation of air pollution, noise, and heat. Citation: Mueller N, Rojas-Rueda D, Basagaña X, Cirach M, Cole-Hunter T, Dadvand P, Donaire-Gonzalez D, Foraster M, Gascon M, Martinez D, Tonne C, Triguero-Mas M, Valentín A, Nieuwenhuijsen M. 2017. Urban and transport pla...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

Delineation of Spatial Variability in the Temperature –Mortality Relationship on Extremely Hot Days in Greater Vancouver, Canada
Conclusions: Our methods provide a data-driven framework for spatial delineation of the temperature–mortality relationship by heat exposure and social vulnerability. The results can be used to map and target the most vulnerable areas for public health intervention. Citation: Ho HC, Knudby A, Walker BB, Henderson SB. 2017. Delineation of spatial variability in the temperature–mortality relationship on extremely hot days in greater Vancouver, Canada. Environ Health Perspect 125:66–75; http://dx.doi.org/10.1289/EHP224 Address correspondence to H.C. Ho, Institute of Environment, Energy and Sustainability, C...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study
Conclusions: TL and CRP levels may help predict the impact of BC exposure on cognitive function in older men. Citation: Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro A III, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. 2017. Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men: the VA Normative Aging Study. Environ Health Perspect 125:76–81; http://dx.doi.org/10.1289/EHP241 Address correspondence to E. Colicino, Department of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Building 1, Room G03,...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

Associations between Source-Specific Fine Particulate Matter and Emergency Department Visits for Respiratory Disease in Four U.S. Cities
Conclusions: We introduced an approach for comparing the chemical compositions of PM2.5 sources across cities and conducted one of the first multicity studies of source-specific PM2.5 and ED visits. Across four U.S. cities, among the primary PM2.5 sources assessed, biomass burning PM2.5 was most strongly associated with respiratory health. Citation: Krall JR, Mulholland JA, Russell AG, Balachandran S, Winquist A, Tolbert PE, Waller LA, Sarnat SE. 2017. Associations between source-specific fine particulate matter and emergency department visits for respiratory disease in four U.S. cities. Environ Health Perspect 125:97...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

Mother ’s Milk and the Environment: Might Chemical Exposures Impair Lactation?
New mothers who quit breastfeeding earlier than they had wanted often chalk it up to not being able to produce enough milk. But a handful of researchers are exploring whether certain environmental exposures may affect some women’s ability to lactate.© Tony Anderson/Getty Images Lactation support includes teaching women techniques to breastfeed and build their milk supply, as well as reassuring them of their ability to nourish their infants.© Phanie/Alamy Stock Photo Education and counseling have been important tools in boosting breastfeeding rates, after decades of ma...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: News Focus January 2017 Source Type: research

In Memoriam: Steve Wing
Virginia T. Guidry is an epidemiologist and writer who worked with Steve Wing for 12 years during her master’s, doctoral, and postdoctoral training at UNC-CH. About This Article open Citation: Guidry VT. 2017. In memoriam: Steve Wing. Environ Health Perspect 125:A1–A2; http://dx.doi.org/10.1289/EHP1406 Final Publication: 1 January 2017 PDF Version (183 KB) Steve Wing, 1952–2016 We lost a beloved scholar, mentor, and environmental justice warrior when Steve Wing passed away on 9 November 2016. He was at home with his family in Pittsboro, North Carolina. Steve was an epidemiologist who studied ...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Perspectives In Memoriam January 2017 Source Type: research

Comment on “Individual and Neighborhood Socioeconomic Status and the Association between Air Pollution and Cardiovascular Disease”
1Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; 2Emory Clinical Cardiovascular Research Institute, Emory University, Atlanta, Georgia, USA About This Article open Citation: Ahmed T, Kelli HM, Sandesara P. 2017. Comment on “Individual and Neighborhood Socioeconomic Status and the Association between Air Pollution and Cardiovascular Disease.” Environ Health Perspect 125:A15; http://dx.doi.org/10.1289/EHP852 Address correspondence to H.M. Kelli, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, 1462 Clifton Rd NE, Ste 513, Atlanta, G...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Perspectives Correspondence January 2017 Source Type: research

Comment on “On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens”
1National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA; 2National Center for Advancing Translational Sciences, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA; 3National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA About This Article open Citation: Houck KA, Judson RS, Knudsen TB, Martin MT, Richard AM, Crofton KM, Sim...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Perspectives Correspondence January 2017 Source Type: research

Connecting PM2.5 Exposure to Insulin Resistance: Oxidative Stress May Be an Intermediate Step
Julia R. Barrett, MS, ELS, a Madison, WI–based science writer and editor, is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences. About This Article open Citation: Barrett JR. 2016. Connecting PM2.5 exposure to insulin resistance: oxidative stress may be an intermediate step. Environ Health Perspect 124:A236; http://dx.doi.org/10.1289/ehp.124-A236 Published: 1 December 2016 PDF Version (385 KB) Related EHP Article Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress Petra Haberzettl, ...
Source: EHP Research - December 1, 2016 Category: Environmental Health Authors: Web Admin Tags: News Science Selections December 2016 Source Type: research

Two Decades of Enhancing Children ’s Environmental Health Protection at the U.S. Environmental Protection Agency
This article provides an overview of public health efforts by the U.S. Environmental Protection Agency (EPA) during the past two decades to protect children’s health from environmental hazards. It highlights examples of concrete steps and accomplishments toward improving environmental protection and health outcomes achieved through public policy, rules and regulations, increased scientific understanding, and public health messaging. Additionally, examples of future challenges for better understanding and improving children’s environmental health are discussed. Citation: Firestone M, Berger M, Foos B, Etzel R....
Source: EHP Research - December 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Brief Communications Children's Health December 2016 Source Type: research

Statistical Approaches for Assessing Health Effects of Environmental Chemical Mixtures in Epidemiology: Lessons from an Innovative Workshop
Conclusions and Future Directions This workshop and its format were unique and novel in the field of environmental chemical mixtures and epidemiology, because participants were asked to conduct statistical analyses of specific model data sets and to compare their results to other statistical approaches. Based on the attendance, number of abstracts submitted, and enthusiastic discussion at the workshop, this format was successful in bringing statisticians and epidemiologists together to work on a common problem. The questions participants were asked to address in their analyses helped focus the discussion on the desired out...
Source: EHP Research - December 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Brief Communications December 2016 Source Type: research

Children ’s Environmental Health: Homes of Influence
Author Affiliations open Children’s Environmental Health Network (CEHN), Washington, DC, USA PDF Version (156 KB) Summary About This Article Over the past two decades, diverse stakeholder groups, representing various disciplines and perspectives (e.g., federal, state and local policy makers; nonprofit organizations; health professionals; and industry), have devoted considerable resources, expertise, and influence toward efforts that wittingly and unwittingly affect children’s environmental health. In this article, we refer to these groups as “homes of influence,” and we summarize the wide...
Source: EHP Research - December 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Perspectives Brief Communications Children's Health December 2016 Source Type: research