Mix Masters: Using a New Tool to Identify Commonly Occurring Chemical Mixtures
PDF Version (898 KB) About This Article Published: 5 December 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article A Method for Identifying Prevalent Chemical Combinations in the U...
Source: EHP Research - December 5, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Compound Interest: Assessing the Effects of Chemical Mixtures
This study … gives the field a new perspective on how to approach the question of adequately and accurately describing how the different chemicals in a mixture can exert biological effects,” says Gabriel Knudsen, a toxicologist at the National Cancer Institute, who was not involved in the study. Knudsen says he hopes that applying this new “mixtures” approach can help inform agencies tasked with setting and enforcing chemical regulations. “More mixtures studies like this one could help shape more well-informed and useful regulations for chemicals that are encountered by people every day,&rdqu...
Source: EHP Research - December 4, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Sanitary Sewer Overflows and Emergency Room Visits for Gastrointestinal Illness: Analysis of Massachusetts Data, 2006 –2007
Conclusions: We demonstrated an association between SSO events and ER visits for GI illness using a case-crossover study design. In light of the aging water infrastructure in the United States and the expected increase in heavy rainfall events, our findings suggest a potential health impact associated with sewage overflows. https://doi.org/10.1289/EHP2048 Received: 13 April 2017 Revised: 20 October 2017 Accepted: 24 October 2017 Published: 28 November 2017 Address correspondence to J.S. Jagai, Division of Environmental and Occupational Health Sciences, School of Public Health, University of Illinois at Chicago, 2121 W....
Source: EHP Research - November 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Ambient Ozone Pollution and Daily Mortality: A Nationwide Study in 272 Chinese Cities
Conclusions: Our findings provide robust evidence of higher nonaccidental and cardiovascular mortality in association with short-term exposure to ambient ozone in China. https://doi.org/10.1289/EHP1849 Received: 4 March 2017 Revised: 3 October 2017 Accepted: 20 October 2017 Published: 21 November 2017 Address correspondence to H. Kan, Department of Environmental Health, School of Public Health, Fudan University, P.O. Box 249, 130 Dong-An Road, Shanghai 200032, China. Telephone: 86 (21) 5423 7908. Email: kanh@fudan.edu.cn and M. Zhou, National Center for Chronic and Noncommunicable Disease Control and Prevention, Chines...
Source: EHP Research - November 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Long-Term Exposure to Transportation Noise in Relation to Development of Obesity —a Cohort Study
Conclusion: Our results link transportation noise exposure to development of obesity and suggest that combined exposure from different sources may be particularly harmful. https://doi.org/10.1289/EHP1910 Received: 17 March 2017 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 20 November 2017 Address correspondence to A. Pyko, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden. Telephone: 46(0) 852487561. Email: Andrei.pyko@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1910). The authors declare they have no actual or potential competing fina...
Source: EHP Research - November 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Exposure to Perfluoroalkyl Substances and Metabolic Outcomes in Pregnant Women: Evidence from the Spanish INMA Birth Cohorts
Conclusions: Although further confirmation is required, the findings from this study suggest that PFAS exposures during pregnancy may influence lipid metabolism and glucose tolerance and thus may impact the health of the mother and her child. https://doi.org/10.1289/EHP1062 Received: 7 September 2016 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 13 November 2017 Address correspondence to M. Vrijheid, ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), 88 Doctor Aiguader, 08003 Barcelona, Catalonia, Spain. Telephone: 93 214 73 46. Email: martine.vrijheid@isglobal.org Supplemental Material ...
Source: EHP Research - November 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Early-Life Selenium Status and Cognitive Function at 5 and 10 Years of Age in Bangladeshi Children
Conclusions: Measures of prenatal and childhood (below the 98th percentile) selenium status were associated with higher cognitive function scores at 5 and 10 y of age. https://doi.org/10.1289/EHP1691 Received: 30 January 2017 Revised: 20 September 2017 Accepted: 21 September 2017 Published: 07 November 2017 Address correspondence to M. Kippler, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77, Stockholm, Sweden. Telephone: 46 8 524 874 07. Email: maria.kippler@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1691). The authors declare they have no actual or pot...
Source: EHP Research - November 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Long-term Fine Particulate Matter Exposure and Nonaccidental and Cause-specific Mortality in a Large National Cohort of Chinese Men
Conclusions: Long-term exposure to PM2.5 was associated with nonaccidental, CVD, lung cancer, and COPD mortality in China. The IER estimator may underestimate the excess relative risk of cause-specific mortality due to long-term exposure to PM2.5 over the exposure range experienced in China and other low- and middle-income countries. https://doi.org/10.1289/EHP1673 Received: 24 February 2017 Revised: 01 September 2017 Accepted: 05 September 2017 Published: 07 November 2017 Address correspondence to M. Zhou, National Center for Chronic Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control ...
Source: EHP Research - November 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

From Intuitive to Evidence Based: Developing the Science of Nature as a Public Health Resource
PDF Version (1.1 MB) About This Article Published: 6 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  Related EHP Article Nature Contact and Human Health: A Research Agenda H...
Source: EHP Research - November 6, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

Biological Cleavage of the C –P Bond in Perfluoroalkyl Phosphinic Acids in Male Sprague-Dawley Rats and the Formation of Persistent and Reactive Metabolites
Conclusions: PFPiAs were metabolized in Sprague-Dawley rats to form persistent PFPAs as well as 1H-PFAs, which contain a labile hydrogen that may undergo further metabolism. These results in rats produced preliminary findings of the pharmacokinetics and metabolism of PFPiAs, which should be further investigated in humans. If there is a parallel between the disposition of these chemicals in humans and rats, then humans with detectable amounts of PFPiAs in their blood may be undergoing continuous exposure. https://doi.org/10.1289/EHP1841 Received: 1 March 2017 Revised: 20 September 2017 Accepted: 21 September 2017 Publish...
Source: EHP Research - November 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

New Blood: The Promise of Environmental Health Citizen Science Projects
PDF Version (4.5 MB) About This Article About This Article Supplemental Material Published: 2 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Published: 2 November 2017 Note to r...
Source: EHP Research - November 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Focus Source Type: research

New Blood: The Promise of Environmental Health Citizen Science Projects
PDF Version (4.5 MB) About This Article Published: 2 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  Mónica Ramírez-Andreotta sat on a folding chair holding a ...
Source: EHP Research - November 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Focus Source Type: research

Erratum: “Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization”
PDF Version (233 KB) About This Article Received: 1 September 2017 Accepted: 9 September 2017 Published: 1 November 2017 Address correspondence to C. Carignan, Department of Environmental Health, Building 1, 14th Floor, 665 Huntington Avenue, Boston, MA 02115 USA. Phone: (617) 432-4572. Email: carignan@hsph.harvard.edu Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assi...
Source: EHP Research - November 1, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Erratum Source Type: research

Unwell: The Public Health Implications of Unregulated Drinking Water
PDF Version (1.5 MB) About This Article Published: 1 November 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days.  Related EHP Article Strategies to Improve Private-Well Water Quality: A ...
Source: EHP Research - November 1, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selection Source Type: research

An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells
Conclusions: Concentrations of MnBP, MBzP and MEHP similar to those found in the urine of pregnant women consistently altered hCG and PPARγ expression in primary placental cells. These findings provide evidence for the molecular basis by which phthalates may alter placental function, and they provide a preliminary mechanistic hypothesis for opposite responses by sex. https://doi.org/10.1289/EHP1539 Received: 23 December 2016 Revised: 6 September 2017 Accepted: 18 September 2017 Published: 31 October 2017 Address correspondence to J.J. Adibi, 130 Desoto Street, Parran Hall 5132, Pittsburgh, PA 15261 USA. Telephone...
Source: EHP Research - October 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research