Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother–Child Study (NewGeneris)
Author Affiliations close 1Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; 2Universitat Pompeu Fabra, Barcelona, Spain; 3CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; 4INSERM (National Institute of Health and Medical Research), U823, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute Albert Bonniot, Grenoble, France; 5Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina, United States; 6Department of Molecular Environmental Epidemiology, National Institute of Environmental Health, Budapest, H...
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

A Study of the Combined Effects of Physical Activity and Air Pollution on Mortality in Elderly Urban Residents: The Danish Diet, Cancer, and Health Cohort
Conclusions: In general, exposure to high levels of traffic-related air pollution did not modify associations indicating beneficial effects of physical activity on mortality. These novel findings require replication in other study populations. (Source: EHP Research)
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Prenatal Air Pollution Exposure and Newborn Blood Pressure
Conclusions: Exposures to PM2.5 and BC in late pregnancy were positively associated with newborn SBP, while O3 was negatively associated with SBP. Longitudinal follow-up will enable us to assess the implications of these findings for health during later childhood and adulthood. (Source: EHP Research)
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Association of Arsenic with Adverse Pregnancy Outcomes–Infant Mortality: A Systematic Review and Meta-Analysis
Conclusions: Arsenic is associated with adverse pregnancy outcomes and infant mortality. The interpretation of the causal association is hampered by methodological challenges and limited studies on dose-response. Exposure to arsenic continues to be a major global health issue and we therefore advocate for high quality prospective studies that include individual level data to quantify the impact of arsenic on adverse pregnancy outcomes/infant mortality. (Source: EHP Research)
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Associations of Mortality with Long-Term Exposures to Fine and Ultrafine Particles, Species and Sources: Results from the California Teachers Study Cohort
Author Affiliations close 1Air Pollution Epidemiology Section, California Office of Environmental Health Hazard Assessment, Oakland, California, USA; 2Department of Civil and Environmental Engineering, University of California, Davis, California, USA; 3Cancer Prevention Institute of California, Berkeley, California, USA; 4City of Hope National Medical Center, Duarte, California, USA About This Article open This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document...
Source: EHP Research - January 23, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Associations of Mortality with Long-Term Exposures to Fine and Ultrafine Particles, Species and Sources: Results from the California Teachers Study Cohort
Author Affiliations close 1Air Pollution Epidemiology Section, California Office of Environmental Health Hazard Assessment, Oakland, California, USA; 2Department of Civil and Environmental Engineering, University of California, Davis, California, USA; 3Cancer Prevention Institute of California, Berkeley, California, USA; 4City of Hope National Medical Center, Duarte, California, USA About This Article open This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document...
Source: EHP Research - January 23, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Lead Exposure and Tremor among Older Men: The VA Normative Aging Study
Author Affiliations close 1Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA; 2Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA; 3VA Boston Healthcare System, Boston, Massachusetts, USA; 4Boston University Schools of Public Health and Medicine, Boston, Massachusetts, USA; 5Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; 6Mailman School of Public Health, Columbia University, New York, USA About This Article open This EHP Advance Publication article has been peer-reviewed, revised, and accepted for p...
Source: EHP Research - January 23, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Lead Exposure and Tremor among Older Men: The VA Normative Aging Study
Author Affiliations close 1Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA; 2Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA; 3VA Boston Healthcare System, Boston, Massachusetts, USA; 4Boston University Schools of Public Health and Medicine, Boston, Massachusetts, USA; 5Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; 6Mailman School of Public Health, Columbia University, New York, USA About This Article open This EHP Advance Publication article has been peer-reviewed, revised, and accepted for p...
Source: EHP Research - January 23, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Antibiotics, Bacteria, and Antibiotic Resistance Genes: Aerial Transport from Cattle Feed Yards via Particulate Matter
Conclusions: Wind dispersed PM from feedyards harbors antibiotics, bacteria, and ARGs. (Source: EHP Research)
Source: EHP Research - January 22, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Antibiotics, Bacteria, and Antibiotic Resistance Genes: Aerial Transport from Cattle Feed Yards via Particulate Matter
Conclusions: Wind dispersed PM from feedyards harbors antibiotics, bacteria, and ARGs. (Source: EHP Research)
Source: EHP Research - January 22, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Markers of Inflammation and Coagulation after Long-Term Exposure to Coarse Particulate Matter: A Cross-Sectional Analysis from the Multi-Ethnic Study of Atherosclerosis
Conclusions: Our cross-sectional analysis provided some evidence that long-term PM10-2.5 exposure was associated with inflammation and coagulation, but associations were modest and depended on particle composition. (Source: EHP Research)
Source: EHP Research - January 20, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Markers of Inflammation and Coagulation after Long-Term Exposure to Coarse Particulate Matter: A Cross-Sectional Analysis from the Multi-Ethnic Study of Atherosclerosis
Conclusions: Our cross-sectional analysis provided some evidence that long-term PM10-2.5 exposure was associated with inflammation and coagulation, but associations were modest and depended on particle composition. (Source: EHP Research)
Source: EHP Research - January 20, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

MicroRNAs as Potential Signatures of Environmental Exposure or Effect: A Systematic Review
Conclusions: MiRNA changes may be sensitive readouts of the effects of acute and chronic environmental exposure. Therefore miRNAs are valuable novel biomarkers for exposure. Further studies should elucidate the role of the mediation effect of miRNA between exposures and effect through all stages of life to provide a more accurate assessment of the consequences of miRNA changes. (Source: EHP Research)
Source: EHP Research - January 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Title: MicroRNAs as Potential Signatures of Environmental Exposure or Effect: A Systematic Review
Conclusions: MiRNA changes may be sensitive readouts of the effects of acute and chronic environmental exposure. Therefore miRNAs are valuable novel biomarkers for exposure. Further studies should elucidate the role of the mediation effect of miRNA between exposures and effect through all stages of life to provide a more accurate assessment of the consequences of miRNA changes. (Source: EHP Research)
Source: EHP Research - January 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts
Conclusions: The current results suggest a novel mechanism through which atrazine may exert relevant biological effects in cancer cells and CAFs. On the basis of our data, atrazine should be included among the environmental contaminants that may elicit estrogenic activity through the GPER-mediated signaling. (Source: EHP Research)
Source: EHP Research - January 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts
Conclusions: The current results suggest a novel mechanism through which atrazine may exert relevant biological effects in cancer cells and CAFs. On the basis of our data, atrazine should be included among the environmental contaminants that may elicit estrogenic activity through the GPER-mediated signaling. (Source: EHP Research)
Source: EHP Research - January 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Effects of Ambient Coarse, Fine, and Ultrafine Particles and Their Biological Constituents on Systemic Biomarkers: A Controlled Human Exposure Study
We examined changes of blood and urinary biomarkers following exposures to three particle sizes. Methods: Fifty healthy non-smoking volunteers, mean age 28 years, were exposed to coarse (2.5-10 µm, mean 213 µg/m3) and fine (0.15-2.5 µm, mean 238 µg/m3) concentrated ambient particles (CAPs), and filtered ambient and/or medical air. Twenty-five participants were exposed to ultrafine CAP (
Source: EHP Research - January 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Effects of Ambient Coarse, Fine, and Ultrafine Particles and Their Biological Constituents on Systemic Biomarkers: A Controlled Human Exposure Study
We examined changes of blood and urinary biomarkers following exposures to three particle sizes. Methods: Fifty healthy non-smoking volunteers, mean age 28 years, were exposed to coarse (2.5-10 µm, mean 213 µg/m3) and fine (0.15-2.5 µm, mean 238 µg/m3) concentrated ambient particles (CAPs), and filtered ambient and/or medical air. Twenty-five participants were exposed to ultrafine CAP (
Source: EHP Research - January 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study
Conclusions: This experimental approach fills critical gaps unaddressed by recent large-scale toxicity testing programs, providing quantitative, experimentally based estimates of human toxicodynamic variability, and also testable hypotheses about mechanisms contributing to inter-individual variation. (Source: EHP Research)
Source: EHP Research - January 13, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study
Conclusions: This experimental approach fills critical gaps unaddressed by recent large-scale toxicity testing programs, providing quantitative, experimentally based estimates of human toxicodynamic variability, and also testable hypotheses about mechanisms contributing to inter-individual variation. (Source: EHP Research)
Source: EHP Research - January 13, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice
Conclusions: We have developed a panel of transcripts as biomarkers which, together with biological endpoints, might be used to screen and evaluate potentially estrogenic chemicals and infer mode of activity. (Source: EHP Research)
Source: EHP Research - January 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice
Conclusions: We have developed a panel of transcripts as biomarkers which, together with biological endpoints, might be used to screen and evaluate potentially estrogenic chemicals and infer mode of activity. (Source: EHP Research)
Source: EHP Research - January 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

E2F1-Mediated FOS Induction in Arsenic Trioxide–Induced Cellular Transformation: Effects of Global H3K9 Hypoacetylation and Promoter-Specific Hyperacetylation in Vitro
Conclusion: Global H3K9 hypo-acetylation and promoter-specific hyper-acetylation facilitate E2F1-mediated FOS induction in As2O3-induced cellular transformation. (Source: EHP Research)
Source: EHP Research - January 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: E2F1-Mediated FOS Induction in Arsenic Trioxide–Induced Cellular Transformation: Effects of Global H3K9 Hypoacetylation and Promoter-Specific Hyperacetylation in Vitro
Conclusion: Global H3K9 hypo-acetylation and promoter-specific hyper-acetylation facilitate E2F1-mediated FOS induction in As2O3-induced cellular transformation. (Source: EHP Research)
Source: EHP Research - January 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Fine Particulate Matter Components and Emergency Department Visits for Cardiovascular and Respiratory Diseases in the St. Louis, Missouri–Illinois, Metropolitan Area
Conclusions: Our findings add to the growing field examining the health effects of PM2.5 components. Combustion-related components of the pollutant mix showed particularly strong associations with cardiorespiratory ED visit outcomes. (Source: EHP Research)
Source: EHP Research - January 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Interaction between Arsenic Exposure from Drinking Water and Genetic Polymorphisms on Cardiovascular Disease in Bangladesh: A Prospective Case-Cohort Study
Conclusions: Associations between CVD and arsenic exposure may be modified by genetic variants related to endothelial dysfunction. (Source: EHP Research)
Source: EHP Research - January 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Associations between Long-Term Exposure to Chemical Constituents of Fine Particulate Matter (PM2.5) and Mortality in Medicare Enrollees in the Eastern United States
Conclusions: Long-term exposures to PM2.5 and several constituents were associated with mortality in the elderly population of the Eastern US. Moreover, some constituents increased the association between long-term exposure to PM2.5 and mortality. These results provide new evidence that chemical composition can partly explain the differential toxicity of PM2.5. (Source: EHP Research)
Source: EHP Research - January 6, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: In Search of “Just Right”: The Challenge of Regulating Arsenic in Rice
Charles W. Schmidt, MS, an award-winning science writer from Portland, ME, has written for Discover Magazine, Science, and Nature Medicine. Background image: © Koji Kitagawa/amanaimages/Corbis About This Article open Citation: Schmidt CW. 2015. In search of “just right”: the challenge of regulating arsenic in rice. Environ Health Perspect 123:A16–A19; http://dx.doi.org/10.1289/ehp.123-A16 News Topics: Agriculture and Farming, Arsenic, Diet and Nutrition, Drinking Water Quality, Food Safety and Regulation, Laws, Regulations, and Policy, Risk Assessment, Soil Pollution, Standards Published: 1 January...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Spheres of Influence Agriculture and Farming Arsenic Diet and Nutrition Drinking Water Quality Food Safety and Regulation Risk Assessment Soil Pollution Standards Source Type: research

Title: The WASH Approach: Fighting Waterborne Disease in Emergency Situations
Refugees collect water from a public tap stand in an Adjumani settlement. © Wendee Nicole Rhino Camp, Arua District. Refugees in Uganda live on land donated by Ugandan nationals. Refugee families are given plots on which they can build temporary shelters and grow crops.© Wendee Nicole Oxfam staff members Tim Sutton (left) and Pius Nzuki Kitonyi (right) with the soon-to-be-repaired water pump in Adjumani. In disaster-affected situations, Oxfam takes a lead in delivering WASH-related services.© Wendee Nicole Hand-operated water pumps are a reliab...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Community Health Disaster Response Drinking Water Quality Infectious Disease Infrastructure International Environmental Health Microbial Agents Sanitation Warfare and Aftermath Water Pollution Source Type: research

Title: ToxCast™ Wants You: Recommendations for Engaging the Broader Scientific Community
Carrie Arnold is a freelance science writer living in Virginia. Her work has appeared in Scientific American, Discover, New Scientist, Smithsonian, and more. About This Article open Citation: Arnold C. 2015. ToxCast™ wants you: recommendations for engaging the broader scientific community. Environ Health Perspect 123:A20; http://dx.doi.org/10.1289/ehp.123-A20 News Topics: Chemical Testing, High-Throughput Screening, Research Issues and Initiatives Published: 1 January 2015 PDF Version (266 KB) Related EHP Article Building a Robust 21st Century Chemical Testing Program at the U.S. Environmental Protection ...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Chemical Testing High-Throughput Screening January 2015 Research Issues and Initiatives Source Type: research

Title: Inner Workings of Arsenic: DNA Methylation Targets Offer Clues to Mechanisms of Toxicity
Lindsey Konkel is a Worcester, MA–based journalist who reports on science, health, and the environment. About This Article open Citation: Konkel L. 2015. Inner workings of arsenic: DNA methylation targets offer clues to mechanisms of toxicity. Environ Health Perspect 123:A21; http://dx.doi.org/10.1289/ehp.123-A21 News Topics: Arsenic, Epigenetics, Molecular Biology, Skin Health Published: 1 January 2015 PDF Version (500 KB) Related EHP Article Gene-Specific Differential DNA Methylation and Chronic Arsenic Exposure in an Epigenome-Wide Association Study of Adults in Bangladesh Maria Argos, Lin Chen, Farzan...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Arsenic Epigenetics January 2015 Molecular Biology Skin Health Source Type: research

Title: “Exported” Deaths and Short-Term PM10 Exposure: Factoring the Impact of Commuting into Mortality Estimates
Julia R. Barrett, MS, ELS, is a Madison, WI–based science writer and editor. She is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences. About This Article open Citation: Barrett JR. 2015. “Exported” deaths attributable to short-term PM10 exposure: factoring the impact of commuting into mortality estimates. Environ Health Perspect 123:A22; http://dx.doi.org/10.1289/ehp.123-A22 News Topics: Air Pollution, Cardiovascular Health, Exposure Science, Particulate Matter (PM), Respiratory Health Published: 1 January 2015 PDF Version (517 KB) Related EHP ...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Air Pollution Cardiovascular Health Exposure Science January 2015 Particulate Matter (PM) Respiratory Health Source Type: research

Title: Potential Mitochondrial Toxicants: Tox21 Screen Identifies Chemicals of Interest
Carol Potera, based in Montana, also writes for Microbe, Genetic Engineering News, and the American Journal of Nursing. About This Article open Citation: Potera C. 2015. Potential mitochondrial toxicants: Tox21 identifies chemicals of interest. Environ Health Perspect 123:A23; http://dx.doi.org/10.1289/ehp.122-A23 News Topics: Biochemistry, Chemical Testing, High-Throughput Screening, Molecular Biology Published: 1 January 2015 PDF Version (946 KB) Related EHP Article Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potentia...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Biochemistry Chemical Testing High-Throughput Screening January 2015 Molecular Biology Source Type: research

Title: Perfluorochemicals and Human Semen Quality: The LIFE Study
Conclusions: Select PFCs were associated with certain semen end points, with the most significant associations observed for PFOSA but with results in varying directions. Citation: Buck Louis GM, Chen Z, Schisterman EF, Kim S, Sweeney AM, Sundaram R, Lynch CD, Gore-Langton RE, Barr DB. 2015. Perfluorochemicals and human semen quality: the LIFE Study. Environ Health Perspect 123:57–63; http://dx.doi.org/10.1289/ehp.1307621 Address correspondence to G.M. Buck Louis, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockvi...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Research Article January 2015 Source Type: research

Title: Genistein Disrupts Glucocorticoid Receptor Signaling in Human Uterine Endometrial Ishikawa Cells
Conclusions: Using Ishikawa cells, we observed that exposure to genistein resulted in distinct changes in gene expression and unique differences in the GR transcriptome. Citation: Whirledge S, Senbanjo LT, Cidlowski JA. 2015. Genistein disrupts glucocorticoid receptor signaling in human uterine endometrial Ishikawa cells. Environ Health Perspect 123:80–87; http://dx.doi.org/10.1289/ehp.1408437 Address correspondence to J.A. Cidlowski, NIH/NIEHS, MD F3-07, P.O. Box 12233, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-1564. E-mail: cidlows1@niehs.nih.gov We thank X. Xu (Integrative Bioinf...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Research Article January 2015 Source Type: research

Title: Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential
Author Affiliations open 1National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda, Maryland, USA; 2Division of the National Toxicology Program, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, USA; 3National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA PDF Version (884 KB) Abstract About This Article Supplemental Material Background: Mitochondri...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Research Article January 2015 Source Type: research

Title: Association between Lung Function in Adults and Plasma DDT and DDE Levels: Results from the Canadian Health Measures Survey
Conclusions: DDT exposures, which may have occurred decades ago, were still detectable among Canadians. Plasma DDT and DDE were negatively associated with lung function parameters. Additional research on the potential effects of DDT use on lung function is warranted. (Source: EHP Research)
Source: EHP Research - December 23, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Developmental Exposure to a Commercial PBDE Mixture: Effects on Protein Networks in the Cerebellum and Hippocampus of Rats
Conclusions: Results suggest that changes in energy metabolism and processes related to neuroplasticity and growth may be involved in the developmental neurotoxicity of PBDEs. (Source: EHP Research)
Source: EHP Research - December 19, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort
Conclusions: In this study we found no evidence to suggest that prenatal PFAS exposure increases the risk of ADHD or childhood autism in children. (Source: EHP Research)
Source: EHP Research - December 19, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Title: Autism Spectrum Disorder and Particulate Matter Air Pollution before, during, and after Pregnancy: A Nested Case–Control Analysis within the Nurses’ Health Study II Cohort
Conclusions: Higher maternal exposure to PM2.5 during pregnancy, in particular the third trimester, was associated with greater odds of her child having ASD. (Source: EHP Research)
Source: EHP Research - December 18, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Title: Comparative Effects of Di(n-Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts
Conclusions: Our findings provide the first comparison of DBP effects in vivo on germ cell number, differentiation and aggregation in human and rat. They show comparable effects on germ cells in both species, but the effects in the human were muted compared with the rat. Nevertheless, phthalate effects on germ cells have potential implications for the next generation, which merits further study. Our results show that the rat is a human-relevant model in which to explore the mechanisms for germ cell effects. (Source: EHP Research)
Source: EHP Research - December 16, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: Interaction Effects of Temperature and Ozone on Lung Function and Markers of Systemic Inflammation, Coagulation, and Fibrinolysis: A Crossover Study of Healthy Young Volunteers
Conclusion: Ozone-induced systemic but not respiratory effects varied according to temperature. Our study suggests that at moderate temperature ozone may activate the fibrinolytic pathway, whilst at elevated temperature it may impair it. These findings provide a biological basis for the interaction between temperature and ozone on mortality observed in some epidemiologic studies. (Source: EHP Research)
Source: EHP Research - December 16, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Title: First Steps toward Harmonized Human Biomonitoring in Europe: Demonstration Project to Perform Human Biomonitoring on a European Scale
Conclusions: We have taken the first steps to assess personal chemical exposures in Europe as a whole. Key success factors were the harmonised protocol development, intensive training and capacity building for field work, chemical analysis and communication, as well as stringent quality control programs for chemical and data analysis. Our project demonstrates the feasibility of a European-wide human biomonitoring framework to support the decision-making process of environmental measures to protect public health. (Source: EHP Research)
Source: EHP Research - December 11, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Title: Children’s Health in Latin America: The Influence of Environmental Exposures
Conclusions: To control environmental threats to children’s health in Latin America, WHO, including PAHO will focus on the most highly prevalent and serious hazards – indoor and outdoor air pollution, water pollution, and toxic chemicals. Strategies for controlling these hazards include developing tracking data on regional trends in children’s environmental health (CEH); building a network of Collaborating Centres; promoting biomedical research in CEH; building regional capacity; supporting development of evidence-based prevention policies; studying the economic costs of chronic diseases in children; and ...
Source: EHP Research - December 5, 2014 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Title: Erratum: “Comparative Assessment of the Effects of Climate Change on Heat- and Cold-Related Mortality in the United Kingdom and Australia”
About This Article open Final Publication: 1 December 2014 PDF Version (57 KB) In the Advance Publication of “Comparative Assessment of the Effects of Climate Change on Heat- and Cold-Related Mortality in the United Kingdom and Australia” by Vardoulakis et al. [Environ Health Perspect 122:1285–1292 (2014); http://dx.doi.org/10.1289/ehp.1307524], Anthony J. McMichael was inadvertently omitted from the list of authors. His name has been included in the final version. The authors regret the error. (Source: EHP Research)
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Erratum December 2014 Source Type: research

Title: Erratum: “Aerial Application of Mancozeb and Urinary Ethylene Thiourea (ETU) Concentrations among Pregnant Women in Costa Rica: The Infants’ Environmental Health Study (ISA)”
About This Article open Final Publication: 1 December 2014 PDF Version (57 KB) In the Advance Publication of “Aerial Application of Mancozeb and Urinary Ethylene Thiourea (ETU) Concentrations among Pregnant Women in Costa Rica: The Infants’ Environmental Health Study (ISA)” by van Wendel de Joode et al. [Environ Health Perspect 122:1323–1328 (2014); http://dx.doi.org/10.1289/ehp.1307679], the unit given for daily creatinine release in pregnant women (1.21 g/day) should have been 1.21 g. It has been corrected in the final version. The authors regret the error. (Source: EHP Research)
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Erratum December 2014 Source Type: research

Title: Erratum: “Nutrient Pollution: A Persistent Threat to Waterways”
About This Article open Final Publication: 1 December 2014 PDF Version (69 KB) The November 2014 News article “Nutrient Pollution: A Persistent Threat to Waterways” [Environ Health Perspect 122:A304–A309; http://dx.doi.org/10.1289/ehp.122-A304] accidentally used the same map to depict both phosphorus and nitrogen pollution in U.S. waterways. In addition, the caption for the phosphorus map incorrectly stated that six of nine ecoregions have phosphorus levels rated “poor” in at least a third of river and stream miles, when in fact this is true of eight ecoregions. EHP regrets the errors. (Source: EHP Research)
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Erratum December 2014 Source Type: research

Title: Erratum: “Performance of Multi-City Land Use Regression Models for Nitrogen Dioxide and Fine Particles”
About This Article open Final Publication: 1 December 2014 PDF Version (80 KB) Wang et al. discovered an error in their article “Performance of Multi-City Land Use Regression Models for Nitrogen Dioxide and Fine Particles” [Environ Health Perspect 122:843–849 (2014); http://dx.doi.org/10.1289/ehp.1307271]. In Table 3, beta values for the NO2 model were incorrect. The corrected table appears below. Table 3 – European models for NO2, PM2.5, and PM2.5 absorbance. View Table (HTML Version) View larger image (TIF File) The authors regret the error. (Source: EHP Research)
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Erratum December 2014 Source Type: research

Title: Advanced Thinking: Potable Reuse Strategies Gain Traction
Richard Dahl is a freelance writer in Boston. He also writes periodically for the Massachusetts Institute of Technology. Background image: © Shutterstock About This Article open Citation: Dahl R. 2014. Advanced thinking: potable reuse strategies gain traction. Environ Health Perspect 122:A332–A335; http://dx.doi.org/10.1289/ehp.122-A332 News Topics: Drinking Water Quality, Infrastructure, Innovative Technologies, Laws, Regulations, and Policy, Natural Resources, Water Security, Water Treatment Published: 1 December 2014 PDF Version (3.3 MB) Advanced treatment capabilities enable cities to augment drinking...
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Spheres of Influence December 2014 Drinking Water Quality Infrastructure Innovative Technologies Natural Resources Water Security Water Treatment Source Type: research

Title: Arising from the Ashes? Environmental Health in Detroit
Detroit Iron and Steel Company, circa 1903, in the early days of Zug Island.© Niday Picture Library/Alamy La’Miya, age 5, uses a nebulizer at her home in River Rouge, a suburb of Detroit. Although some asthma indicators have improved in recent years, Detroit’s hospitalization rate for the disease is three times the state average.52© Ami Vitale/Panos Pictures   A researcher changes the filter on a mobile air sampler parked near Maybury Elementary School, an area of Detroit with an especially high prevalence of asthma.© Jim West/Alamy ...
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Agriculture and Farming Air Pollution Asthma Cardiovascular Health Community Health December 2014 Dust Health Disparities Infrastructure Mental Health Trade and Commerce Urban Issues Source Type: research