Occupational Exposure to Benzene and Non-Hodgkin Lymphoma in a Population-Based Cohort: The Shanghai Women’s Health Study
Conclusions: Our findings, using a population-based prospective cohort of women with diverse occupational histories, provide additional evidence that occupational exposure to benzene is associated with NHL risk. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the public...
Source: EHP Research - March 6, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Prenatal and Postnatal Exposure to Persistent Organic Pollutants and Infant Growth: A Pooled Analysis of Seven European Birth Cohorts
Conclusion: To our knowledge, this is the largest study to date of POPs exposure and infant growth, and with state of the art exposure modelling. Prenatal p,p‘-DDE was associated with increased infant growth, and postnatal PCB-153 with decreased growth at European exposure levels. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the ci...
Source: EHP Research - March 6, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Prediagnostic Serum Organochlorine Concentrations and Metastatic Prostate Cancer: A Nested Case–Control Study in the Norwegian Janus Serum Bank Cohort
Conclusions: Our study highlights the importance of estimating associations with specific organochlorine chemicals and suggests a possible role of OC insecticides and PCBs in the etiology of metastatic prostate cancer. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the...
Source: EHP Research - March 3, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice
Conclusions: These results demonstrate that adipocyte AhR mediates PCB-induced adipose inflammation and impairment of glucose homeostasis in mice. Moreover, deficiency of AhR in adipocytes augmented the development of obesity, indicating that endogenous ligand(s) for AhR regulate adipose homeostasis. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number ...
Source: EHP Research - March 3, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Maternal Blood Manganese and Early Neurodevelopment: The Mothers and Children’s Environmental Health (MOCEH) Study
Conclusion: While no cut-off point has been established to define manganese toxicity, both high and low blood manganese levels may be associated with neurobehavioral function in infants. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation:&...
Source: EHP Research - March 3, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Diversity Outbred: A New Generation of Mouse Model
Charles W. Schmidt, MS, an award-winning science writer from Portland, ME, has written for Discover Magazine, Science, and Nature Medicine. About This Article open Citation: Schmidt CW. 2015. Diversity Outbred: a new generation of mouse model. Environ Health Perspect 123:A64–A67; http://dx.doi.org/10.1289/ehp.123-A64 News Topics: Animal Models, Chemical Testing, Genetic Research, Genomics, Research Issues and Initiatives Published: 1 March 2015 PDF Version (3.6 MB) The use of genetically identical mice in toxicology studies can make it tricky to extrapolate findings to people. A new mouse model known as the Di...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Spheres of Influence Animal Models Chemical Testing Genetic Research Genomics March 2015 Research Issues and Initiatives Source Type: research

Hand-Me-Down Hazard: Flame Retardants in Discarded Foam Products
This study also found the highest body burdens among black girls.Researchers have also found that low-income residences tend to have higher levels of flame retardants in dust.44 Little has been published on levels of newer flame retardants in the bodies or homes of lower-income populations. Few hard data exist to explain these disparities in flame retardant exposures, says Ami Zota, an assistant professor at George Washington University’s Department of Environmental and Occupational Health. It is possible that the physical weathering and crumbling of treated foam in older or cheaper furniture, which is more often fou...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News and Policy Cancer Children's Health Dust Flame Retardants Health Disparities Industry Issues Laws March 2015 Occupational Health Polybrominated Diphenyl Ethers (PBDEs) Regulations Surveillance and Monitori Source Type: research

Air Pollution and ASDs: Homing In on an Environmental Risk Factor
This study provides some really nice continuing evidence of the potential relationship between air pollution and autism across the entire United States,” says Heather Volk, an epidemiologist at the University of Southern California, who was not involved in the study. Previous work in animal models has suggested a possible mechanism for how air pollution exposure may increase ASD risk. Mice exposed to concentrated ambient ultrafine PM showed ventriculomegaly, altered neurochemistry, and activation of glial cells in the brain.13 These responses, which occurred preferentially in male mice, signal an inflammatory respons...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Featured News Science Selection Air Pollution Children's Health March 2015 Neurologic Health Particulate Matter (PM) Risk Assessment Source Type: research

Comparing Models: DBP Effects in Rat and Human Germ Cells
This study highlights that attention should be shifting towards the seminiferous cord effects of phthalate exposure during development,” says Kim Boekelheide, a professor of pathology and laboratory medicine at the Brown University School of Medicine, who was not involved in the study. “I think this article points that out nicely and suggests some tools that can be used to look at those effects.” The implications of the current results for human health are unclear, however. “Although our results show small effects of DBP on germ cells in the human fetal testis, none of these effects are directly rel...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Featured News Science Selection Animal Models Endocrine Disruptors March 2015 Men's Health Phthalates Reproductive Health Source Type: research

Roadmap for Children’s Health: Controlling Diverse Environmental Exposures in Latin America
Carol Potera, based in Montana, also writes for Microbe, Genetic Engineering News, and the American Journal of Nursing. About This Article open Citation: Potera C. 2015. Roadmap for children’s health: controlling diverse environmental exposures in Latin America. Environ Health Perspect 123:A70; http://dx.doi.org/10.1289/ehp.123-A70 News Topics: Arsenic, Asthma, Cancer, Children’s Health, Drinking Water Quality, Electronics and Electronic Waste, Household Air Pollution, International Environmental Health, Lead, Pesticides, Surveillance and Monitoring Published: 1 March 2015 PDF Version (947 KB) Related EHP...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Featured News Science Selection Arsenic Asthma Cancer Children's Health Drinking Water Quality Electronics and Electronic Waste Household Air Pollution International Environmental Health Lead March 2015 Pesticides Surveillance Source Type: research

Continental Reference Point: Harmonized Human Biomonitoring across Europe
Kris S. Freeman has written for the National Institutes of Health and the National Park Service. About This Article open Citation: Freeman KS. 2015. Continental reference point: harmonized human biomonitoring across Europe. Environ Health Perspect 123:A71; http://dx.doi.org/10.1289/ehp.123-A71 News Topics: Children’s Health, Exposure Science, International Environmental Health, Mercury, Phthalates, Research Issues and Initiative, Smoking and Secondhand Smoke (SHS), Surveillance and Monitoring Published: 1 March 2015 PDF Version (775 KB) Related EHP Article First Steps toward Harmonized Human Biomonitoring in Eu...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Featured News Science Selection Children's Health Exposure Science International Environmental Health March 2015 Mercury Phthalates Research Issues and Initiatives Smoking and Secondhand Smoke (SHS) Surveillance and Monitoring Source Type: research

Jenny Pronczuk de Garbino: A Global Champion for Children’s Health
1Department of Preventive Medicine, and 2Arnhold Global Health Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA; 3National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA About This Article open Citation: Landrigan PJ, Suk WA. 2015. Jenny Pronczuk de Garbino: A global champion for children’s health. Environ Health Perspect 123:A52–A53; http://dx.doi.org/10.1289/ehp.1408293. E-mail: phil.landrigan@mssm.edu Final Publication: 1 March 2015 PDF Version (284 KB) On 20 Se...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Editorial March 2015 Source Type: research

Theodora (Theo) Colborn: 1927–2014
About This Article open Citation: Grossman E, et al. 2015. Theodora (Theo) Colborn: 1927–2014. Environ Health Perspect 123:A54; http://dx.doi.org/10.1289/ehp.1509743. Final Publication: 1 March 2015 PDF Version (294 KB) Theodora Colborn, research scientist and environmental activist, died 14 December 2014 at the age of 87. As the scientist who coined the term “endocrine disruptor,” Theo—as we had the privilege to call her—played a watershed role in the field of environmental health science, particularly in raising public awareness of the effects of chemical contaminants on human health and...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Announcement March 2015 Source Type: research

Children’s Health in Latin America: The Influence of Environmental Exposures
Conclusions: To control environmental threats to children’s health in Latin America, WHO, including PAHO, will focus on the most highly prevalent and serious hazards—indoor and outdoor air pollution, water pollution, and toxic chemicals. Strategies for controlling these hazards include developing tracking data on regional trends in children’s environmental health (CEH), building a network of Collaborating Centres, promoting biomedical research in CEH, building regional capacity, supporting development of evidence-based prevention policies, studying the economic costs of chronic diseases in children, and d...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Review March 2015 Source Type: research

Comparative Effects of Di(n-Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts
Conclusions: Our findings provide the first comparison of DBP effects on germ cell number, differentiation, and aggregation in human testis xenografts and in vivo in rats. We observed comparable effects on germ cells in both species, but the effects in the human were muted compared with those in the rat. Nevertheless, phthalate effects on germ cells have potential implications for the next generation, which merits further study. Our results indicate that the rat is a human-relevant model in which to explore the mechanisms for germ cell effects. Citation: van den Driesche S, McKinnell C, Calarrão A, Kennedy L, H...
Source: EHP Research - March 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Research Article March 2015 Source Type: research

Combining PM2.5 Component Data from Multiple Sources: Data Consistency and Characteristics Relevant to Epidemiological Analyses of Predicted Long-Term Exposures
Conclusions: Investigators conducting epidemiological studies of long-term PM2.5 components need to be mindful of the features of the monitoring data and incorporate this understanding into the design of their monitoring campaigns and the development of their exposure prediction models. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the ci...
Source: EHP Research - February 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

In Utero and Childhood Polybrominated Diphenyl Ether Exposures and Body Mass at Age 7 Years: The CHAMACOS Study
Conclusions: We estimated sex-specific associations with maternal PBDE levels during pregnancy and body mass index at age 7 with positive associations in boys and negative associations in girls. Children’s serum BDE-153 concentrations were inversely associated with body mass index at age 7 with no difference by sex. Future studies should examine the longitudinal trends in obesity with PBDE exposure and changes in hormonal environment as children transition through puberty, as well as evaluate the potential for reverse causality. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for ...
Source: EHP Research - February 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Blood Pressure, Left Ventricular Geometry, and Systolic Function in Children Exposed to Inorganic Arsenic
This study investigates the association between iAs exposure, blood pressure (BP) and functional and anatomical echocardiographic parameters in children. Methods: A cross sectional study of 161 children between 3-8 years was conducted in Central Mexico. The total concentration of arsenic (As) species in urine (U-tAs) was determined by HG-CT-AAS and lifetime iAs exposure was estimated by multiplying As concentrations measured in drinking water by the duration of water consumption in years (LAsE, µg/L-year). BP was measured by standard protocols, and M-mode echocardiographic parameters were determined by ultrasonograph...
Source: EHP Research - February 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Rapid Responses and Mechanism of Action for Low-Dose Bisphenol S on ex Vivo Rat Hearts and Isolated Myocytes: Evidence of Female-Specific Proarrhythmic Effects
Conclusion: Rapid exposure to low-dose BPS has pro-arrhythmic impact on female rat hearts; these effects at the organ, cellular and molecular levels are remarkably similar to those reported for BPA. Evaluation of the bioactivity and safety of BPS and other BPA analogs is necessary before they are used as BPA alternatives in consumer products. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon ...
Source: EHP Research - February 26, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Natural Cause Mortality and Long-Term Exposure to Particle Components: An Analysis of 19 European Cohorts within the Multi-Center ESCAPE Project
Author Affiliations open 1Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands; 2Danish Cancer Society Research Center, Copenhagen, Denmark; 3Department of Epidemiology, Lazio Regional Health Service, Rome, Italy; 4Center for Epidemiology and Screening, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; 5Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany; 6IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany, and Medical Faculty, University of Düsseldorf, Germany; 7In...
Source: EHP Research - February 24, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

A Case-Cohort Study of Cadmium Body Burden and Gestational Diabetes Mellitus in American Women
We examined the association between body burden of Cd and GDM risk. Methods: We used 140 GDM cases and 481 randomly selected non-case subcohort members from the Omega Study to conduct a case-cohort study. Creatinine (Cr) corrected Cd in early pregnancy urine (U-Cd) was measured by inductively coupled plasma mass spectrometry. Tertiles (
Source: EHP Research - February 24, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Ambient Air Pollution and Adult Asthma Incidence in Six European Cohorts (ESCAPE)
Conclusions: Results are suggestive of a deleterious effect of ambient air pollution on asthma incidence in adults. Further research with improved personal-level exposure assessment (versus residential exposure assessment only) and phenotypic characterization is needed. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will ...
Source: EHP Research - February 24, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Humans
Conclusions: The IARC Monographs have made, and continue to make, major contributions to the scientific underpinning for societal actions to improve the public’s health. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Pearce...
Source: EHP Research - February 24, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Commentary Source Type: research

Background Ionizing Radiation and the Risk of Childhood Cancer: A Census-Based Nationwide Cohort Study
Author Affiliations open 1Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; 2Swiss Tropical and Public Health Institute, Basel, Switzerland; 3University of Basel, Basel, Switzerland; 4Department of Oncology, University Children’s Hospital Zurich, Zürich, Switzerland; 5Department of Oncology/Hematology, Children’s Hospital, Cantonal Hospital Lucerne, Lucerne, Switzerland PDF Version (426 KB) Abstract About This Article Supplemental Material Article-Level Metrics Background: Exposure to medium or high doses of ionizing radiation is a kno...
Source: EHP Research - February 23, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Estimated Exposure to Arsenic in Breastfed and Formula-Fed Infants in a United States Cohort
Author Affiliations open 1Children’s Environmental Health and Disease Prevention Research Center at Dartmouth, Hanover, New Hampshire, USA; 2Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire, USA; 3Trace Element Analysis Laboratory, Department of Earth Sciences, Dartmouth College, Hanover, New Hampshire, USA; 4Department of Epidemiology and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA; 5Department of Pharmacology and Toxicology, University of Arizona, Tuscon, Arizona, USA. *These authors have contributed equ...
Source: EHP Research - February 23, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Reproductive Toxicity of a Mixture of Regulated Drinking-Water Disinfection By-Products in a Multigenerational Rat Bioassay
Conclusions: A mixture of regulated DBPs at up to 2000× the MCLs had no adverse effects on fertility, pregnancy maintenance, prenatal survival, postnatal survival, or birth weights. Delayed puberty at ≥1000× may have been secondary to reduced water consumption. Male nipple retention and compromised sperm motility at 2000× may have been secondary to reduced body weights. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced w...
Source: EHP Research - February 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Examination of the Safety of Pediatric Vaccine Schedules in a Non-Human Primate Model: Assessments of Neurodevelopment, Learning, and Social Behavior
Conclusions: This comprehensive five-year, case-control study, which closely examined the effects of pediatric vaccines on early primate development, provided no consistent evidence of neurodevelopmental deficits or aberrant behavior in vaccinated animals. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to acc...
Source: EHP Research - February 18, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Mercury Exposure and Antinuclear Antibodies among Females of Reproductive Age in the United States: NHANES
Conclusions: Methylmercury, at low levels generally considered safe, was associated with subclinical autoimmunity among reproductive-age females. Autoantibodies may predate clinical disease by years, thus methylmercury exposure may be relevant to future autoimmune disease risk. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, y...
Source: EHP Research - February 10, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice
Conclusions: These novel findings are consistent with Notch3 and Notch4 as susceptibility genes for ozone-induced lung injury, and suggest that Notch receptors protect against innate immune inflammation. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication pr...
Source: EHP Research - February 6, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Estimating Pesticide Exposure from Dietary Intake and Organic Food Choices: The Multi-Ethnic Study of Atherosclerosis (MESA)
Author Affiliations open 1Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA; 2Department of Epidemiology, University of Washington, Seattle, Washington, USA; 3Department of Environmental Health, Harvard University, Boston, Massachusetts, USA; 4Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center, Houston, Texas, USA; 5Department of Medicine, University of Washington, Seattle, Washington, USA PDF Version (1.5 MB) Abstract About This Article Article-Level Metrics Back...
Source: EHP Research - February 5, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

New Link in the Food Chain? Marine Plastic Pollution and Seafood Safety
Investigators are researching whether consumption of plastic debris by marine organisms translates into toxic exposures for people who eat seafood.© Alex RM/Alamy Different marine plastics resemble foods eaten at various trophic levels. These plastic bags look like the jellyfish eaten by turtles.© Norbert Wu/Minden Pictures/Corbis Plastic debris can travel far from its point of departure—this beach in Svalbard, Norway, for instance, is only about 600 miles from the North Pole. A 2014 study reported finding large quantities of microplastics frozen into Arctic ice.52&co...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Bisphenol A (BPA) Dioxins and Furans Ecology and Wildlife Endocrine Disruptors February 2015 Flame Retardants Food Safety and Regulation Marine and Coastal Science Nanomaterials Personal Care Products Phthalat Source Type: research

Seeds of Toxicity? Erythrocytes and Lead-Associated Kidney Damage
In this study the researchers hypothesized that lead exposure increases the number of PS-tagged erythrocytes, which are then consumed by the proximal tubular epithelial cells in the kidney. They further hypothesized that iron from the erythrocytes accumulates in the kidney cells, where it triggers the formation of reactive oxygen species, the first step in oxidative damage. The ultimate biological outcome of toxic exposures is frequently a combination of two factors—individual responses of multiple tissues and, subsequently, complex interactions of altered tissues—says study coauthor Jin-Ho Chung, a professor i...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Cardiovascular Health February 2015 Lead Metals Urinary Health Source Type: research

The View from Afar: Satellite-Derived Estimates of Global PM2.5
Lindsey Konkel is a Worcester, MA–based journalist who reports on science, health, and the environment. About This Article open Citation: Konkel L. 2015. The view from afar: satellite-derived estimates of global PM2.5. Environ Health Perspect 123:A43; http://dx.doi.org/10.1289/ehp.123-A43 News Topics: Air Pollution, International Environmental Health, Particulate Matter (PM), Surveillance and Monitoring Published: 1 February 2015 PDF Version (1.6 MB) Related EHP Article Use of Satellite Observations for Long-Term Exposure Assessment of Global Concentrations of Fine Particulate Matter Aaron van Donkelaar, Randal...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Air Pollution February 2015 International Environmental Health Particulate Matter (PM) Surveillance and Monitoring Source Type: research

Tracking Alternative Flame Retardants: Hand-to-Mouth Exposures in Adults
Kellyn S. Betts writes about environmental contaminants, hazards, and technology for solving environmental problems for publications including EHP and Environmental Science & Technology. About This Article open Citation: Betts KS. 2015. Tracking alternative flame retardants: hand-to-mouth exposures in adults. Environ Health Perspect 123:A44; http://dx.doi.org/10.1289/ehp.123-A44 News Topics: Dust, Flame Retardants, Men’s Health, Personal Care Products, Polybrominated Diphenyl Ethers (PBDEs), Women’s Health Published: 1 February 2015 PDF Version (350 KB) Related EHP Article Monitoring Indoor Expo...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Dust February 2015 Flame Retardants Men's Health Personal Care Products Polybrominated Diphenyl Ethers (PBDEs) Women's Health Source Type: research

Shrimp Consumption after Deepwater Horizon: No Evidence of Excess Risks for Vietnamese Americans
Janet L. Pelley, MS, based in Toronto, ON, Canada, writes for Chemical & Engineering News and Frontiers in Ecology and the Environment. About This Article open Citation: Pelley JL. 2015. Shrimp consumption after Deepwater Horizon: no evidence of excess risks for Vietnamese Americans. Environ Health Perspect 123:A45; http://dx.doi.org/10.1289/ehp.123-A45 News Topics: Cancer, Disaster Response, Food Safety and Regulation, Health Disparities, Polycyclic Aromatic Hydrocarbons (PAHs), Risk Assessment Published: 1 February 2015 PDF Version (393 KB) Related EHP Article A Targeted Health Risk Assessment Following t...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Cancer Disaster Response February 2015 Food Safety and Regulation Health Disparities Polycyclic Aromatic Hydrocarbons (PAHs) Risk Assessment Source Type: research

Evaluating Health Risks from Inhaled Polychlorinated Biphenyls: Research Needs for Addressing Uncertainty
Conclusions: In certain contexts, inhalation exposure to PCBs may contribute more to total PCB exposure than previously assumed. New epidemiological and toxicological studies addressing the potential health impacts of inhaled PCBs may be useful for quantifying exposure–response relationships and evaluating risks. Citation: Lehmann GM, Christensen K, Maddaloni M, Phillips LJ. 2015. Evaluating health risks from inhaled polychlorinated biphenyls: research needs for addressing uncertainty. Environ Health Perspect 123:109–113; http://dx.doi.org/10.1289/ehp.1408564 Address correspondence to G.M. Leh...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Commentary February 2015 Source Type: research

Human Health Effects of Dichloromethane: Key Findings and Scientific Issues
Conclusion: The 2011 IRIS assessment of dichloromethane provides insights into the toxicity of a commonly used solvent. Citation: Schlosser PM, Bale AS, Gibbons CF, Wilkins A, Cooper GS. 2015. Human health effects of dichloromethane: key findings and scientific issues. Environ Health Perspect 123:114–119; http://dx.doi.org/10.1289/ehp.1308030 Address correspondence to G.S. Cooper, National Center for Environmental Assessment (8601-P), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460 USA. Telephone: (703) 347-8636. E-mail: Cooper.Glinda@epa.gov The views expressed are ...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Commentary February 2015 Source Type: research

Erythrophagocytosis of Lead-Exposed Erythrocytes by Renal Tubular Cells: Possible Role in Lead-Induced Nephrotoxicity
Conclusions: Our data strongly suggest that erythrophagocytosis and subsequent iron deposition in renal tubular cells could significantly enhance nephrotoxicity following lead exposure, providing insight on lead-associated kidney damages. Citation: Kwon SY, Bae ON, Noh JY, Kim K, Kang S, Shin YJ, Lim KM, Chung JH. 2015. Erythrophagocytosis of lead-exposed erythrocytes by renal tubular cells: possible role in lead-induced nephrotoxicity. Environ Health Perspect 123:120–127; http://dx.doi.org/10.1289/ehp.1408094 Address correspondence to J.-H. Chung, Institute of Pharmaceutical Sciences, College of Ph...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Research Article February 2015 Source Type: research

Association between Lifetime Exposure to Inorganic Arsenic in Drinking Water and Coronary Heart Disease in Colorado Residents
Author Affiliations open 1Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado, USA; 2Department of Preventive Medicine, State University of New York, Stony Brook, New York, USA PDF Version (176 KB) Abstract About This Article Supplemental Material Background: Chronic diseases, including coronary heart disease (CHD), have been associated with ingestion of drinking water with high levels of inorganic arsenic (> 1,000 μg/L). However, associations have been inconclusive in populations with lower levels (
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Research Article February 2015 Source Type: research

Use of Satellite Observations for Long-Term Exposure Assessment of Global Concentrations of Fine Particulate Matter
Conclusions: Satellite observations provide insight into global long-term changes in ambient PM2.5 concentrations. Satellite-derived estimates and ground-based PM2.5 observations from this study are available for public use. Citation: van Donkelaar A, Martin RV, Brauer M, Boys BL. 2015. Use of satellite observations for long-term exposure assessment of global concentrations of fine particulate matter. Environ Health Perspect 123:135–143; http://dx.doi.org/10.1289/ehp.1408646 Address correspondence to A. van Donkelaar, Department of Physics and Atmospheric Science, Dalhousie University, 6300 Cob...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Research Article February 2015 Source Type: research

A Review of Nonoccupational Pathways for Pesticide Exposure in Women Living in Agricultural Areas
Author Affiliations close 1Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA; 2Department of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut, USA; 3Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA; 4Division of Surveillance, Hazard Evaluation and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA; 5National Exposure Research Laboratory, U.S. Environmental Protection Agency, Re...
Source: EHP Research - January 30, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Predicting Hospitalization for Heat-Related Illness at the Census Tract Level: Accuracy of a Generic Heat Vulnerability Index in Phoenix, Arizona (USA)
Author Affiliations close 1School of Sustainability, Arizona State University, Tempe, Arizona, USA; 2School of Geographic Sciences and Urban Planning, Arizona State University, Tempe, Arizona, USA; 3Johnson-Shoyama Graduate School of Public Policy, University of Saskatchewan, Saskatoon, Saskatchewan, Canada About This Article open This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as...
Source: EHP Research - January 30, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Arsenic Exposure and Prevalence of the Varicella Zoster Virus in the United States: NHANES (2003-2004 and 2009-2010)
Conclusions: In this cross-sectional analysis urinary arsenic was inversely associated with VZV IgG seroprevalence in the US population. This finding is in accordance with clinical observations of zoster virus reactivation from high doses of arsenic. Additional studies are needed to confirm the association and evaluate causal mechanisms. (Source: EHP Research)
Source: EHP Research - January 30, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Estimating the Number of Vulnerable People in the United States Exposed to Residential Wood Smoke
Center for Environmental Health Sciences, University of Montana, Missoula, Montana, USA About This Article open E-mail: curtis.noonan@umontana.edu The authors’ research related to residential biomass combustion is supported by the National Institute of Environmental Health Sciences (grants 1R01ES022583, 1R01ES022649, 1R01ES016336). The authors declare they have no actual or potential competing financial interests. Published: 1 February 2015 PDF Version (111 KB) Rogalsky et al. (2014) recently estimated the number of homes and individuals at risk of adverse health effects from exposure to emissions from r...
Source: EHP Research - January 30, 2015 Category: Environmental Health Authors: Web Admin Tags: Correspondence February 2015 Source Type: research

Estimating the Number of Vulnerable People in the United States Exposed to Residential Wood Smoke: Rogalsky et al. Respond
1Georgetown University School of Medicine, Georgetown University, Washington, DC, USA; 2Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA; 3Department of Environmental Health, East Tennessee State University, Johnson City, Tennessee, USA About This Article open E-mail: dkr24@georgetown.edu The authors declare they have no actual or potential competing financial interests. Published: 1 February 2015 PDF Version (85 KB) We appreciate the thoughtful comments by Noonan et al. and consi...
Source: EHP Research - January 30, 2015 Category: Environmental Health Authors: Web Admin Tags: Correspondence February 2015 Source Type: research

Erratum: “A Prospective Study of Growth and Biomarkers of Exposure to Aflatoxin and Fumonisin during Early Childhood in Tanzania”
About This Article open Final Publication: 1 February 2015 PDF Version (48 KB) After Advance Publication of “A Prospective Study of Growth and Biomarkers of Exposure to Aflatoxin and Fumonisin during Early Childhood in Tanzania” (Environ Health Perspect 123:173–178; http://dx.doi.org/10.1289/ehp.1408097), Shirima et al. discovered errors in the models used for analyses of the joint effects of aflatoxin and fumonisin. After they ran the corrected joint-effects models, it became clear that the data were not sufficient to produce interpretable results. Therefore, the authors removed the joint-effects ana...
Source: EHP Research - January 30, 2015 Category: Environmental Health Authors: Web Admin Tags: Erratum February 2015 Source Type: research

Variation in Urinary Flow Rates According to Demographic Characteristics and Body Mass Index in NHANES: Potential Confounding of Associations between Health Outcomes and Urinary Biomarker Concentrations
Conclusions: UFR and UFRBW exhibit systematic variations with age, sex, race/ethnicity, and BMI category. These variations can confound assessments of potential exposure-health outcome associations based on urinary concentration. Analyte excretion rates are valuable exposure metrics in such assessments. (Source: EHP Research)
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Air Pollution and Atherosclerosis: A Cross-Sectional Analysis of Four European Cohort Studies in the ESCAPE Study
Conclusions: Using a standardized exposure and analytical protocol in four European cohorts, cross-sectional associations between CIMT and the eight ESCAPE markers of long-term residential air pollution exposure did not reach statistical significance. The additional meta-analysis of CIMT and PM2.5 across all published studies also was positive but not significant. (Source: EHP Research)
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Metro Nature, Environmental Health, and Economic Value
Conclusions: Metro nature provides diverse and substantial benefits to human populations in cities. This article begins to address the need for development of valuation methodologies, and new approaches to understanding the potential economic outcomes of these benefits. (Source: EHP Research)
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Association between Ambient Air Pollution and Diabetes Mellitus in Europe and North America: Systematic Review and Meta-Analysis
Author Affiliations close 1Swiss Tropical and Public Health Institute, Basel, Switzerland; 2University of Basel, Basel, Switzerland; 3Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland; 4IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany; 5Medical Faculty, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany About This Article open This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using th...
Source: EHP Research - January 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research