Effects of Radon and UV Exposure on Skin Cancer Mortality in Switzerland
Conclusions: There is considerable variation in radon and UV exposure across Switzerland. Our study suggests both are relevant risk factors for skin cancer mortality. A better understanding of the role of the UV radiation and radon exposure is of high public health relevance. https://doi.org/10.1289/EHP825 Received: 19 July 2016 Revised: 28 October 2016 Accepted: 15 November 2016 Published: 16 June 2017 Address correspondence to D. Vienneau, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051, Basel, Switzerland. Telephone: 41 (0) 61-284-8398. E-mail: d...
Source: EHP Research - June 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Associations of Prenatal Urinary Bisphenol A Concentrations with Child Behaviors and Cognitive Abilities
Conclusion: Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort, and some associations were stronger among boys. https://doi.org/10.1289/EHP984 Received: 18 August 2016 Revised: 09 December 2016 Accepted: 12 December 2016 Published: 16 June 2017 Address correspondence to Joseph M. Braun, Department of Epidemiology, Box G-S121-2, Brown University, Providence, RI 02912 USA. Telephone: (401) 863-5397. E-mail: joseph_braun_1@brown.edu Supplemental Material is available online (https://doi.org/10.1289/EHP984). The authors declare they have no actual or potential competing f...
Source: EHP Research - June 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children
Conclusion: Our results indicate alterations in systemic inflammatory markers in 8-y-old children in relation to early-life exposure to traffic-related air pollution. https://doi.org/10.1289/EHP460 Received: 04 May 2016 Revised: 20 October 2016 Accepted: 07 November 2016 Published: 16 June 2017 Address correspondence to O. Gruzieva, Karolinska Institutet, Institute of Environmental Medicine, Nobels väg 13 Box 210, SE-17177, Stockholm, Sweden. Telephone: 46 8 524 80022. Fax: 46 8 304571. E-mail: olena.gruzieva@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP460). The authors declare they h...
Source: EHP Research - June 16, 2017 Category: Environmental Health Authors: Karla Gonzalez Tags: Research Source Type: research

Humoral Immunity in Arsenic-Exposed Children in Rural Bangladesh: Total Immunoglobulins and Vaccine-Specific Antibodies
Conclusions: Arsenic exposure increased tIgG and tIgE in plasma, and tended to decrease mumps-specific IgG in children at 9 years of age. https://doi.org/10.1289/EHP318 Received: 09 April 2016 Revised: 09 October 2016 Accepted: 24 October 2016 Published: 14 June 2017 Address correspondence to R. Raqib, Immunobiology, Nutrition and Toxicology Laboratory, Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Mohakhali, Dhaka-1212, Bangladesh. Telephone: 880-2-9827068. E-mail: rubhana@icddrb.org Supplemental Material is available online (https://doi.org/10.1289/EHP318). The authors declare they have n...
Source: EHP Research - June 15, 2017 Category: Environmental Health Authors: Karla Gonzalez Tags: Research Source Type: research

Individual and Joint Effects of Early-Life Ambient PM2.5 Exposure and Maternal Prepregnancy Obesity on Childhood Overweight or Obesity
Conclusions: In the present study, we observed that early life exposure to PM2.5 may play an important role in the early life origins of COWO and may increase the risk of COWO in children of mothers who were overweight or obese before pregnancy beyond the risk that can be attributed to MPBMI alone. Our findings emphasize the clinical and public health policy relevance of early life PM2.5 exposure. https://doi.org/10.1289/EHP261 Received: 29 March 2016 Revised: 08 August 2016 Accepted: 23 August 2016 Published: 14 June 2017 Address correspondence to X. Wang, Center on the Early Life Origins of Disease, Department of P...
Source: EHP Research - June 14, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Advancing Alternative Analysis: Integration of Decision Science
Conclusions: We advance four recommendations: a) engaging the systematic development and evaluation of decision approaches and tools; b) using case studies to advance the integration of decision analysis into alternatives analysis; c) supporting transdisciplinary research; and d) supporting education and outreach efforts. https://doi.org/10.1289/EHP483 Received: 16 December 2015 Revised: 09 May 2016 Accepted: 19 September 2016 Published: 13 June 2017 Address correspondence to T. F. Malloy, UCLA School of Law, Box 951476, 3113 Law Building, Los Angeles, CA, 90095-1476. Telephone: 310-794-5278. E-mail:malloy@law.ucla.e...
Source: EHP Research - June 14, 2017 Category: Environmental Health Authors: Karla Gonzalez Tags: Review Source Type: research

Age at Menopause: Do Chemical Exposures Play a Role?
PDF Version (2.2 MB) About This Article Published: 12 June 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. With its associated hot flashes, mood swings, and insomnia, menopause can be a chal...
Source: EHP Research - June 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: News Focus Source Type: research

Human CYP2A13 and CYP2F1 Mediate Naphthalene Toxicity in the Lung and Nasal Mucosa of CYP2A13/2F1-Humanized Mice
Conclusion: CYP2F1 is an active enzyme. Both CYP2A13 and CYP2F1 are active toward NA in the CYP2A13/2F1-humanized mice, where they play significant roles in NA-induced respiratory tract toxicity. https://doi.org/10.1289/EHP844 Received: 20 July 2016 Revised: 22 October 2016 Accepted: 07 November 2016 Published: 08 June 2017 Address correspondence to L. Van Winkle, Center for Health and the Environment, Building 3792, Room 129, Old Davis Rd., UC Davis, Davis, CA 95616 USA. Telephone: (530) 754-9060. E-mail: lsvanwinkle@ucdavis.edu , and X. Ding, College of Nanoscale Science and Engineering, SUNY Polytechnic Institute,...
Source: EHP Research - June 9, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

Environmental Exposures to Lead, Mercury, and Cadmium and Hearing Loss in Adults and Adolescents: KNHANES 2010 –2012
Conclusions: The results of the present study suggest that exposure to environmental lead and cadmium in adults and exposure to environmental cadmium in adolescents may play a role in the risk of hearing loss. https://doi.org/10.1289/EHP565 Received: 02 January 2016 Revised: 27 May 2016 Accepted: 19 September 2016 Published: 08 June 2017 Address Correspondence to Yoon-Hyeong Choi, 155 Gaetbeol-ro, Yeonsu-gu, Incheon, Republic of Korea, 21999. Telephone: 82-32-899-6586. E-mail: yoonchoi@gachon.ac.kr Supplemental Material is available online (https://doi.org/10.1289/EHP565). The authors declare they have no actual or p...
Source: EHP Research - June 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Genome-wide Association Study of Susceptibility to Particulate Matter –Associated QT Prolongation
Conclusions: The findings suggest that biologically plausible genetic factors may alter susceptibility to PM10-associated QT prolongation in populations protected by the U.S. Environmental Protection Agency’s National Ambient Air Quality Standards. Independent replication and functional characterization are necessary to validate our findings. https://doi.org/10.1289/EHP347 Received: 11 April 2016 Revised: 07 September 2016 Accepted: 19 September 2016 Published: 08 June 2017 Address correspondence to R. Gondalia, Department of Epidemiology, University of North Carolina, 137 E. Franklin St., Chapel Hill, NC 27514. Te...
Source: EHP Research - June 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Assessment of the Probability of Autochthonous Transmission of Chikungunya Virus in Canada under Recent and Projected Climate Change
This study identifies that southern Canada may be the very northern limit for transmission of these pathogens with climate change. Other factors need to be explored however, which include understanding when and where Canadian travelers are likely to return, infrastructure in Canada that may support vector populations in what would be expected to be climatically unsuitable regions, and whether or not there are other competent vectors in Canada. Further research to close the gap on our current understanding of CHIKV and CHIKV vectors, improved surveillance on Ae. albopictus in North America, and enhanced climate projection m...
Source: EHP Research - June 5, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies
Conclusions: This is, to our knowledge, the first report of an association between house dust endotoxin and leukocyte count in a national survey. The finding was replicated in a farming population. Peripheral leukocyte count may be influenced by residential endotoxin exposure in diverse settings. https://doi.org/10.1289/EHP661 Received: 15 June 2016 Revised: 13 September 2016 Accepted: 27 September 2016 Published: 31 May 2017 Address correspondence to: M.B. Fessler, MD, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., P.O. Box 12233, Maildrop D2-01, Research Triangle Park, NC 27709. Tele...
Source: EHP Research - May 31, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

Time-series Analysis of Heat Waves and Emergency Department Visits in Atlanta, 1993 to 2012
Conclusions: Heat waves can confer additional risks of ED visits beyond those of daily air temperature, even in a region with high air-conditioning prevalence. https://doi.org/10.1289/EHP44 Received: 29 February 2016 Revised: 13 October 2016 Accepted: 24 October 2016 Published: 31 May 2017 Address correspondence to H.H. Chang, Department of Biostatistics and Bioinformatics, Emory University, 1518 Clifton Rd. NE, Atlanta, Georgia 30322. Telephone: (404) 712-4627; E-mail: howard.chang@emory.edu Supplemental Material is available online (https://doi.org/10.1289/EHP44). The authors declare they have no...
Source: EHP Research - May 31, 2017 Category: Environmental Health Authors: Terrie Young Tags: Research Source Type: research

Expansion of the Lyme Disease Vector Ixodes scapularis in Canada Inferred from CMIP5 Climate Projections
Conclusion: Our results highlight the potential for climate change to have an effect on future Lyme disease risk in Canada even if the Paris Agreement’s goal to keep global warming below 2°C is achieved, although mitigation reducing emissions from RCP8.5 levels to those of RCP6.0 or less would be expected to slow tick invasion after the 2030s. https://doi.org/10.1289/EHP57 Received: 02 March 2016 Revised: 26 August 2016 Accepted: 30 August 2016 Published: 31 May 2017 Address correspondence to H. Beltrami, Earth Science Department, Physical Sciences Center, PO Box 5000, 1 West St, Antigonish, NS B2G 1W5. Telepho...
Source: EHP Research - May 31, 2017 Category: Environmental Health Authors: Terrie Young Tags: Research Source Type: research