Biopolymers as promising vehicles for drug delivery to the brain
Drug Metab Rev. 2023 Nov 13:1-16. doi: 10.1080/03602532.2023.2281855. Online ahead of print.ABSTRACTThe brain is a privileged organ, tightly guarded by a network of endothelial cells, pericytes, and glial cells called the blood brain barrier. This barrier facilitates tight regulation of the transport of molecules, ions, and cells from the blood to the brain. While this feature ensures protection to the brain, it also presents a challenge for drug delivery for brain diseases. It is, therefore, crucial to identify molecules and/or vehicles that carry drugs, cross the blood brain barrier, and reach targets within the central ...
Source: Drug Metabolism Reviews - November 13, 2023 Category: Drugs & Pharmacology Authors: Rajeswara Babu Mythri Mysore Rajeswara Babu Aishwarya Source Type: research