Opioids and frequency counts in the US Food and Drug Administration Adverse Event Reporting System (FAERS) database: a quantitative view of the epidemic
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - August 19, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Selexipag in the management of pulmonary arterial hypertension: an update
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - August 5, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Critical evaluation of the validity of drug promotion materials in Ethiopia
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - July 24, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Utilization of over-the-counter analgesics in two private medical insurance schemes in South Africa
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - July 17, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Evaluation of vancomycin use in university-affiliated hospitals in Southern Khorasan Province (East Iran) based on HICPAC guidelines
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - April 8, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Adherence to risk management guidelines for drugs which cause vitamin D deficiency & ndash; big data from the Swedish health system
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - March 22, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Evaluation to improve the quality of medication preparation and administration in pediatric and adult intensive care units
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - March 19, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Pulmonary hypertension occurring with diazoxide use in a preterm infant with hypoglycemia
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - March 4, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Pattern of medication use in geriatric patients at primary healthcare facilities in Karawang, Indonesia
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - February 8, 2019 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Ceftriaxone-associated nephrolithiasis and gallstone in adults
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - December 12, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Clinical factors predicting drug-induced liver injury due to flucloxacillin
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - November 21, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

A pilot study on secondhand tobacco exposure: parental knowledge about health impact and feasibility of cessation
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - October 12, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Predictors of non adherence to antiretroviral therapy at an urban HIV care and treatment center in Tanzania
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - August 21, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Development and validation of a questionnaire to self-assess patient knowledge of direct oral anticoagulants (KODOA-test)
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - July 20, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Long-term safety profile of tolvaptan in autosomal dominant polycystic kidney disease patients: TEMPO Extension Japan Trial [Corrigendum]
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - July 16, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Therapeutic potential of medicinal marijuana: an educational primer for health care professionals
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - June 11, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Concomitant use of opioid medications with triptans or serotonergic antidepressants in US office-based physician visits
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - May 3, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Evaluating cardiac risk: exposure response analysis in early clinical drug development
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - April 18, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Evaluation of vancomycin therapy in the adult ICUs of a teaching hospital in southern Iran
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - April 5, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Calculating reading ease score of patient package inserts in Iran
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - March 19, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Prevalence of medication errors in primary health care at Bahrain Defence Force Hospital & ndash; prescription-based study
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - February 7, 2018 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Older adults and high-risk medication administration in the emergency department
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - November 8, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Long-term safety profile of tolvaptan in autosomal dominant polycystic kidney disease patients: TEMPO Extension Japan Trial
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - October 25, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

A suspected case of autoinduction of voriconazole metabolism in a patient with cerebral aspergillosis
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - September 8, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Early rehospitalizations of frail elderly patients & ndash; the role of medications: a clinical, prospective, observational trial
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - August 18, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Potential drug & ndash;drug interactions in inpatients treated at the Internal Medicine ward of Tikur Anbessa Specialized Hospital
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - August 14, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Prediction of drug-related problems in diabetic outpatients in a number of hospitals, using a modeling approach
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - July 28, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Adaptation of the European Commission-recommended user testing method to patient medication information leaflets in Japan
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - June 14, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Update on the renal toxicity of iodinated contrast drugs used in clinical medicine
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - May 22, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Patient safety attitudes of pharmacy students in an Ethiopian university: a cross-sectional study
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - May 8, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Update on the usage and safety of epinephrine auto-injectors, 2017
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - March 21, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Quantifying the relationship between patient characteristics and involvement in developing and implementing a treatment plan
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - January 16, 2017 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Development and validation of evaluation tools of nursing students & rsquo; clinical pharmacology unit
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - December 15, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Implementation of co-trimoxazole preventive therapy policy for malaria in HIV-infected pregnant women in the public health facilities in Tanzania
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - December 13, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Pattern of chemotherapy-related adverse effects among adult cancer patients treated at Gondar University Referral Hospital, Ethiopia: a cross-sectional study
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - December 7, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Positive clinical outcomes derived from using Streptococcus salivarius K12 to prevent streptococcal pharyngotonsillitis in children: a pilot investigation
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - November 21, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Point prevalence of hospital-acquired infections in two teaching hospitals of Amhara region in Ethiopia
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - August 23, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Extent of dispensing prescription-only medications without a prescription in community drug retail outlets in Addis Ababa, Ethiopia: a simulated-patient study
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - July 14, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Topiramate-induced maculopathy in IgG4-related disease
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - June 8, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

The virgin land of quality management: a first measure of patient safety climate at the National Hospital of the Faroe Islands
Solvejg Kristensen,1,2 Naina Túgvustein,3 Hjørdis Zachariassen,3 Svend Sabroe,4 Paul Bartels,1,5 Jan Mainz5,6 1The Danish Clinical Registries, Aarhus, 2Department of Health Science and Technology, Aalborg University, Denmark; 3National Hospital of the Faroe Islands, Torshavn, Faroe Islands; 4Department of Public Health, Aarhus University, Aarhus, 5Department of Clinical Medicine, Aalborg University, Aalborg, 6Aalborg University Hospital, Psychiatry, Aalborg, Denmark Purpose: The Faroe Islands are formally part of the Kingdom of Denmark, but the islands enjoy extensive autonomy as home ruled. In Denmark, exten...
Source: Drug, Healthcare and Patient Safety - April 26, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Patient safety climate at the Faroe Islands
Kristensen S, Túgvustein N, Zachariassen H, Sabroe S, Bartels P, Mainz J (Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - April 26, 2016 Category: Drugs & Pharmacology Source Type: research

Seasonality in acute liver injury? Findings in two health care claims databases
The objective of this study was to determine whether there were any temporal patterns in hospitalizations for ALI that would correspond to assumed acetaminophen use in cold/flu season. Methods: In the period 2002–2010, monthly hospitalization rates for ALI using a variety of case definitions were calculated. Data sources included Truven MarketScan® Commercial Claims and Encounters (CCAE) and Medicare Supplemental and Coordination of Benefits (MDCR) databases. We performed a statistical test for seasonality of diagnoses using the periodic generalized linear model. To validate that the test can distinguish seasonal...
Source: Drug, Healthcare and Patient Safety - March 31, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Seasonality in acute liver injury?
Weinstein RB, Schuemie MJ, Ryan PB, Stang PE (Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - March 30, 2016 Category: Drugs & Pharmacology Source Type: research

Safety of apixaban for venous thromboembolism prophylaxis: the evidence to date
Vladimir Trkulja Department of Pharmacology, Zagreb University School of Medicine, Zagreb, Croatia Abstract: Apixaban, a direct orally active anticoagulant (selective, direct factor Xa inhibitor) is approved for (primary) prevention of venous thromboembolism (VTE) in patients undergoing elective total-hip or total-knee arthroplasty, for acute treatment/prevention of recurrent events in patients with VTE, and extended prophylaxis in patients with a history of VTE. Another approved use is prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. The present overview focuses on the safety of...
Source: Drug, Healthcare and Patient Safety - February 18, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Safety of apixaban in VTE
Trkulja V (Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - February 17, 2016 Category: Drugs & Pharmacology Source Type: research

Clinical utility, safety, and efficacy of pregabalin in the treatment of fibromyalgia
Santosh Bhusal,1 Sherilyn Diomampo,1 Marina N Magrey2 1Division of Rheumatology, Metrohealth Medical Center, 2Case Western Reserve University School of Medicine at Metrohealth Medical Center, Cleveland OH, USA Abstract: Fibromyalgia is a chronic debilitating medical syndrome with limited therapeutic options. Pregabalin, an anticonvulsant and α-2-Δ subunit receptor ligand, is one of the anchor drugs approved by the US Food and Drug Administration for the treatment of fibromyalgia. The drug has shown clinically meaningful benefits across multiple symptom domains of fibromyalgia. Efficacy of pregabalin in fibromya...
Source: Drug, Healthcare and Patient Safety - February 16, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

Pregabalin in fibromyalgia
Bhusal S, Diomampo S, Magrey MN (Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - February 16, 2016 Category: Drugs & Pharmacology Source Type: research

A fatal adverse effect of cefazolin administration: severe brain edema in a patient with multiple meningiomas
We present a rare case of fatal cefazolin hypersensitivity in a female who was diagnosed with multiple meningiomas and scheduled for craniotomy and tumor removal. Immediately after cefazolin IV administration, the patient developed acute hypertensive crisis, which resolved within 10 minutes after the treatment. This was followed by unexplained metabolic acidosis. The patient then developed severe brain edema 100 minutes later. The patient had facial edema when her face was exposed for the next 30 minutes. A computed tomography scan revealed global brain edema with herniation. She was admitted to the intensive care unit for...
Source: Drug, Healthcare and Patient Safety - February 9, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research

A fatal adverse effect of cefazolin administration
Tribuddharat S, Sathitkarnmanee T, Kitkhuandee A, Theerapongpakdee S, Ngamsaengsirisup K, Chanthawong S (Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - February 8, 2016 Category: Drugs & Pharmacology Source Type: research

Benefit & ndash;risk assessment of golimumab in the treatment of refractory ulcerative colitis
(Source: Drug, Healthcare and Patient Safety)
Source: Drug, Healthcare and Patient Safety - February 2, 2016 Category: Drugs & Pharmacology Tags: Drug, Healthcare and Patient Safety Source Type: research