An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.ABSTRACTNanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases mo...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Wenqing Liang Chao Zhou Songtao Jin Lifeng Fu Hengjian Zhang Xiaogang Huang Hengguo Long Wenyi Ming Jiayi Zhao Source Type: research
The direct transfer approach for transcellular drug delivery
Drug Deliv. 2023 Dec;30(1):2288799. doi: 10.1080/10717544.2023.2288799. Epub 2023 Nov 30.ABSTRACTA promising paradigm for drug administration that has garnered increasing attention in recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT requires direct cell-cell contact and facilitates unidirectional and bidirectional matter exchange between neighboring cells. Consequently, DT enables fast and deep penetration of drugs into the targeted tissues. This comprehensive review discusses the direct transfer concept, which can be delineated into the following three distinct modalities: memb...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Yi-Fan Wang Ze-Fan Shen Fang-Yue Xiang Heng Wang Pu Zhang Qi Zhang Source Type: research
An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.ABSTRACTNanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases mo...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Wenqing Liang Chao Zhou Songtao Jin Lifeng Fu Hengjian Zhang Xiaogang Huang Hengguo Long Wenyi Ming Jiayi Zhao Source Type: research
The direct transfer approach for transcellular drug delivery
Drug Deliv. 2023 Dec;30(1):2288799. doi: 10.1080/10717544.2023.2288799. Epub 2023 Nov 30.ABSTRACTA promising paradigm for drug administration that has garnered increasing attention in recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT requires direct cell-cell contact and facilitates unidirectional and bidirectional matter exchange between neighboring cells. Consequently, DT enables fast and deep penetration of drugs into the targeted tissues. This comprehensive review discusses the direct transfer concept, which can be delineated into the following three distinct modalities: memb...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Yi-Fan Wang Ze-Fan Shen Fang-Yue Xiang Heng Wang Pu Zhang Qi Zhang Source Type: research
An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.ABSTRACTNanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases mo...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Wenqing Liang Chao Zhou Songtao Jin Lifeng Fu Hengjian Zhang Xiaogang Huang Hengguo Long Wenyi Ming Jiayi Zhao Source Type: research
The direct transfer approach for transcellular drug delivery
Drug Deliv. 2023 Dec;30(1):2288799. doi: 10.1080/10717544.2023.2288799. Epub 2023 Nov 30.ABSTRACTA promising paradigm for drug administration that has garnered increasing attention in recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT requires direct cell-cell contact and facilitates unidirectional and bidirectional matter exchange between neighboring cells. Consequently, DT enables fast and deep penetration of drugs into the targeted tissues. This comprehensive review discusses the direct transfer concept, which can be delineated into the following three distinct modalities: memb...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Yi-Fan Wang Ze-Fan Shen Fang-Yue Xiang Heng Wang Pu Zhang Qi Zhang Source Type: research
An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.ABSTRACTNanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases mo...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Wenqing Liang Chao Zhou Songtao Jin Lifeng Fu Hengjian Zhang Xiaogang Huang Hengguo Long Wenyi Ming Jiayi Zhao Source Type: research
The direct transfer approach for transcellular drug delivery
Drug Deliv. 2023 Dec;30(1):2288799. doi: 10.1080/10717544.2023.2288799. Epub 2023 Nov 30.ABSTRACTA promising paradigm for drug administration that has garnered increasing attention in recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT requires direct cell-cell contact and facilitates unidirectional and bidirectional matter exchange between neighboring cells. Consequently, DT enables fast and deep penetration of drugs into the targeted tissues. This comprehensive review discusses the direct transfer concept, which can be delineated into the following three distinct modalities: memb...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Yi-Fan Wang Ze-Fan Shen Fang-Yue Xiang Heng Wang Pu Zhang Qi Zhang Source Type: research
An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.ABSTRACTNanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases mo...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Wenqing Liang Chao Zhou Songtao Jin Lifeng Fu Hengjian Zhang Xiaogang Huang Hengguo Long Wenyi Ming Jiayi Zhao Source Type: research
The direct transfer approach for transcellular drug delivery
Drug Deliv. 2023 Dec;30(1):2288799. doi: 10.1080/10717544.2023.2288799. Epub 2023 Nov 30.ABSTRACTA promising paradigm for drug administration that has garnered increasing attention in recent years is the direct transfer (DT) of nanoparticles for transcellular drug delivery. DT requires direct cell-cell contact and facilitates unidirectional and bidirectional matter exchange between neighboring cells. Consequently, DT enables fast and deep penetration of drugs into the targeted tissues. This comprehensive review discusses the direct transfer concept, which can be delineated into the following three distinct modalities: memb...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Yi-Fan Wang Ze-Fan Shen Fang-Yue Xiang Heng Wang Pu Zhang Qi Zhang Source Type: research
An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.ABSTRACTNanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases mo...
Source: Drug Delivery - December 1, 2023 Category: Drugs & Pharmacology Authors: Wenqing Liang Chao Zhou Songtao Jin Lifeng Fu Hengjian Zhang Xiaogang Huang Hengguo Long Wenyi Ming Jiayi Zhao Source Type: research
Lipidization as a tool toward peptide therapeutics
We describe how individual types of lipidization are achieved and describe their advantages and drawbacks. Peptide modifications are performed with the goal of reaching a longer half-life, reducing immunogenicity and improving bioavailability. In the case of neuropeptides, lipidization aids their activity in the central nervous system after the peripheral administration. At the end of our review, we summarize all lipidized peptide-based drugs that are currently on the market.PMID:38010881 | DOI:10.1080/10717544.2023.2284685 (Source: Drug Delivery)
Source: Drug Delivery - November 27, 2023 Category: Drugs & Pharmacology Authors: Aneta My šková David S ýkora Jaroslav Kune š Lenka Malet ínská Source Type: research
