Understanding alcohol motivation using the Alcohol Purchase Task: A methodological systematic review
Behavioral economics is a framework that integrates concepts from economics and operant psychology to understand seemingly irrational decision making (e.g., substance abuse, risky sexual behavior; Bickel and Vuchinich, 2000). The behavioral economic methodology encompasses several constructs that have proved especially useful in understanding alcohol use disorder (AUD; MacKillop, 2016). Among the most frequently used constructs are delay discounting, proportionate alcohol-related reinforcement, alcohol-savings discretionary expenditure, and demand. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - August 2, 2018 Category: Addiction Authors: Brent A. Kaplan, Rachel N.S. Foster, Derek D. Reed, Michael Amlung, James G. Murphy, James MacKillop Source Type: research
Effect of electronic screening and brief intervention on hazardous or harmful drinking among adults in the hospital outpatient setting: A randomized, double-blind, controlled trial
Globally, over three million deaths per annum (one in 20) are caused by alcohol consumption (World Health Organization, 2014a). Alcohol screening and brief intervention (SBI), which is “a structured set of questions designed to identify individuals at risk for alcohol use problems, followed by a brief discussion between an individual and a service provider, with referral to specialized treatment as needed” (American Public Health Association and Education Development Center In c, 2008), is estimated to reduce alcohol consumption by 20 grams per week (95% CI: -28 to -12) in non-dependent patients presenting for primar...
Source: Drug and Alcohol Dependence - August 2, 2018 Category: Addiction Authors: Natalie A. Johnson, Kypros Kypri, John B. Saunders, Richard Saitz, John Attia, Joanna Latter, Patrick McElduff, Adrian Dunlop, Christopher Doran, Luke Wolfenden, Jim McCambridge Tags: Full length article Source Type: research
The effect of quinine in two bottle choice procedures in C57BL6 mice: opioid preference, somatic withdrawal, and pharmacokinetic outcomes
Opioid abuse remains a persistent public health concern in the United States, resulting in over 33,000 deaths in 2015 alone (Rudd et al., 2016). From 1999 to 2015, the number of overdose deaths attributable to prescription opioids has quadrupled (Center for Disease Control, 2017), highlighting prescribed analgesics as a substantial contributing factor to the epidemic. Similar to heroin, prescription opioids possess unwanted effects in addition to their therapeutic properties, notably abuse liability (Jimenez et al., 2017). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - August 2, 2018 Category: Addiction Authors: Travis W. Grim, Scarlet Jinhong Park, Cullen L. Schmid, Robert B. Laprairie, Michael Cameron, Laura M. Bohn Tags: Full length article Source Type: research
Comparing the contribution of prescribed opioids to opioid-related hospitalizations across Canada: a multi-jurisdictional cross-sectional study
In Canada, over 2800 deaths were opioid-related in 2016, and 13 people are hospitalized every day from an opioid-related toxicity event (Canadian Institute for Health Information and Canadian Centre on Substance Abuse, 2016; Government of Canada, 2017). Although these rates have risen considerably across the country over the past two decades, considerable geographic variation exists in the rates of fatal and non-fatal overdoses (Alberta Health, 2017; British Columbia Coroners Service, 2017a, b; Canadian Institute for Health Information and Canadian Centre on Substance Abuse, 2016; Gomes et al., 2017). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - August 1, 2018 Category: Addiction Authors: Tara Gomes, Wayne Khuu, Diana Craiovan, Diana Martins, Jordan Hunt, Kathy Lee, Mina Tadrous, Muhammad M. Mamdani, J. Michael Paterson, David N. Juurlink Tags: Full length article Source Type: research
Social networks and substance use after transitioning into permanentsupportive housing
Substance use disorders are the most common mental health conditions among persons experiencing homelessness (Fazel et al., 2008), and engaging in substance use is associated with worse outcomes for this population, including chronic homelessness (Fichter and Quadflieg, 2006; Kuhn and Culhane, 1998; Lipton et al., 2000), morbidity (Shannon et al., 2006), and mortality (Beijer et al., 2011). Permanent supportive housing (PSH), which combines stable housing with health and other supportive services, is an evidence-based, long-term solution for ending chronic homelessness (Byrne et al., 2014; Rog et al., 2014; Smelson et al.,...
Source: Drug and Alcohol Dependence - July 28, 2018 Category: Addiction Authors: Harmony Rhoades, Wichada La Motte-Kerr, Lei Duan, Darlene Woo, Eric Rice, Benjamin Henwood, Taylor Harris, Suzanne L. Wenzel Tags: Full length article Source Type: research
Substance use patterns among women living with HIV compared with the general female population of Canada
Substance use is a common health risk behavior among people living with HIV (PLWH), who have a demonstrated greater prevalence than their general population counterparts (Ikeda et al., 2016; Mdodo et al., 2015; Tron et al., 2014). Substance use is considered a major barrier to successful HIV care and treatment (Cofrancesco et al., 2008; Cook et al., 2009; Durvasula and Miller, 2014; Gonzalez et al., 2011; Hicks et al., 2007; Malta et al., 2008) despite the substantial advances obtained from combination antiretroviral therapy (cART), e.g., improved life expectancy in PLWH (2008). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - July 28, 2018 Category: Addiction Authors: Mostafa Shokoohi, Greta R. Bauer, Angela Kaida, Ashley Lacombe-Duncan, Mina Kazemi, Brenda Gagnier, Alexandra de Pokomandy, Mona Loutfy, On Behalf of the CHIWOS Research Team Tags: Full length article Source Type: research
Social networks and substance use after transitioning into permanent supportive housing
Substance use disorders are the most common mental health conditions among persons experiencing homelessness (Fazel et al., 2008), and engaging in substance use is associated with worse outcomes for this population, including chronic homelessness (Fichter and Quadflieg, 2006; Kuhn and Culhane, 1998; Lipton et al., 2000), morbidity (Shannon et al., 2006), and mortality (Beijer et al., 2011). Permanent supportive housing (PSH), which combines stable housing with health and other supportive services, is an evidence-based, long-term solution for ending chronic homelessness (Byrne et al., 2014; Rog et al., 2014; Smelson et al.,...
Source: Drug and Alcohol Dependence - July 28, 2018 Category: Addiction Authors: Harmony Rhoades, Wichada La Motte-Kerr, Lei Duan, Darlene Woo, Eric Rice, Benjamin Henwood, Taylor Harris, Suzanne L. Wenzel Tags: Full length article Source Type: research
Cue reactivity and opioid blockade in amphetamine dependence: A randomized, controlled fMRI study
Amphetamine use disorder is a global health problem for which there is still no approved pharmacological treatment. In Northern Europe, amphetamine has dominated injection drug use for decades (Hakansson et al., 2009). One of the few promising pharmacological treatments for amphetamine dependence is the opioid antagonist naltrexone (Karila et al., 2010), which is currently used clinically for the treatment of alcohol and opioid dependence (Lobmaier et al., 2011; R ösner et al., 2010). In a number of human laboratory studies, it has consistently been shown that pre-treatment with naltrexone attenuates the subjective effect...
Source: Drug and Alcohol Dependence - July 26, 2018 Category: Addiction Authors: Joar Guterstam, Nitya Jayaram-Lindstr öm, Jonathan Berrebi, Predrag Petrovic, Martin Ingvar, Peter Fransson, Johan Franck Tags: Full length article Source Type: research
Prenatal and concurrent cocaine, alcohol, marijuana, and tobacco effects on adolescent cognition and attention
Understanding the long-term effects of prenatal drug and alcohol exposures is a critical component of informed public health prevention and intervention efforts, as well as in developing knowledge regarding environmental effects on neurocognitive development. The cocaine epidemic of the late 1980 ’s created a large U.S. population of children who were polydrug-exposed in the prenatal period who are now adolescents or young adults. Cocaine is a potent monoaminergic neurotransmitter that can impact fetal and long-term neurocognitive development directly through disruption of neural ontogeny, through vascular effects, and i...
Source: Drug and Alcohol Dependence - July 25, 2018 Category: Addiction Authors: Lynn T. Singer, Meeyoung O. Min, Sonia Minnes, Elizabeth Short, Barbara Lewis, Adelaide Lang, Miaoping Wu Tags: Full length article Source Type: research
Longitudinal associations between youth tobacco and substance use in waves 1 and 2 of the population assessment of tobacco and health (path) study
Cigarette smoking is the leading preventable cause of morbidity and mortality in the United States (U.S.) (U.S. Department of Health and Human Services, 2014). Despite overall declines in conventional cigarette use in the past several decades, non-cigarette tobacco-product use among U.S. youth has been increasing (Arrazola et al., 2015; Johnston et al., 2017). Wave 1 (2013 –2014) estimates from the Population Assessment of Tobacco and Health (PATH) Study show that, overall, 22% of youths had ever used tobacco (Kasza et al., 2017). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - July 25, 2018 Category: Addiction Authors: Marushka L. Silveira, Kevin P. Conway, Victoria R. Green, Karin A. Kasza, James D. Sargent, Nicolette Borek, Cassandra A. Stanton, Amy Cohn, Nahla Hilmi, K. Michael Cummings, Raymond S. Niaura, Elizabeth Y. Lambert, Mary F. Brunette, Izabella Zandberg, Su Tags: Full length article Source Type: research
Prenatal and concurrent cocaine, alcohol, marijuana, and tobacco effects of adolescent cognition and attention
Understanding the long-term effects of prenatal drug and alcohol exposures is a critical component of informed public health prevention and intervention efforts, as well as in developing knowledge regarding environmental effects on neurocognitive development. The cocaine epidemic of the late 1980 ’s created a large U.S. population of children who were polydrug-exposed in the prenatal period who are now adolescents or young adults. Cocaine is a potent monoaminergic neurotransmitter that can impact fetal and long-term neurocognitive development directly through disruption of neural ontogeny, through vascular effects, and i...
Source: Drug and Alcohol Dependence - July 25, 2018 Category: Addiction Authors: Lynn T. Singer, Meeyoung O. Min, Sonia Minnes, Elizabeth Short, Barbara Lewis, Adelaide Lang, Miaoping Wu Source Type: research
Correlation of cytokines, BDNF levels, and memory function in patients with opioid use disorder undergoing methadone maintenance treatment
The lifetime prevalence rate of opioid use disorder (OUD) is high —2.1% in the US (Grant et al., 2016) and 0.22% globally (Degenhardt et al., 2014)—and is the cause of substantial public health problems throughout the globe (Degenhardt et al., 2014). The development of OUD is associated with multiple genetic, environmental, and developmental risk factors (Volk ow et al., 2016). In addition to the classical etiology for OUD, emerging evidence also suggests that dysregulated neuroinflammation is involved in the development of addiction (Coller and Hutchinson, 2012). (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - July 25, 2018 Category: Addiction Authors: Tzu-Yun Wang, Sheng-Yu Lee, Yun-Hsuan Chang, Shiou-Lan Chen, Po-See Chen, Chun-Hsien Chu, San-Yuan Huang, Nian-Sheng Tzeng, I. Hui Lee, Kao Chin Chen, Yen-Kuang Yang, Shih-Heng Chen, Jau-Shyong Hong, Ru-Band Lu Tags: Full length article Source Type: research
Falling rates of marijuana dependence among heavy users
Since the turn of the century, the United States has seen dramatic changes in marijuana policy, use, and social context. Eight states and Washington DC have legalized possession, use, production, and sale of marijuana for non-medical use; more than thirty states have legalized some form of medical marijuana, often with dispensaries. Perceptions of marijuana ’s risks have been falling (Pacek et al., 2015), and approval for legalization is now nearly two-thirds (Gallup, 2017). Marijuana use has also changed in other ways, e.g., increasing THC potency, an increasing acceptance and availability of marijuana for medical use, ...
Source: Drug and Alcohol Dependence - July 25, 2018 Category: Addiction Authors: Steven Davenport Tags: Short communication Source Type: research
Study characteristics influence the efficacy of substance abuse treatments: A meta-analysis of medications for alcohol use disorder
Clinical researchers have long recognized that study characteristics can influence estimates of treatment efficacy (i.e., the difference between active and control condition outcomes) (Del Re et al., 2013a; Etter et al., 2007; Yildiz et al., 2011). However, which and how much study characteristics predict outcomes is unclear. Knowledge of which specific characteristics lead to increased or decreased effect sizes of treatments and whether effects are due to changes in the active or placebo condition should improve interpretation of findings from clinical trials and inform researchers of the potential impact of methodologica...
Source: Drug and Alcohol Dependence - July 24, 2018 Category: Addiction Authors: Elias M. Klemperer, John R. Hughes, Shelly Naud Tags: Review Source Type: research
Illicit drug use and work in a model therapeutic workplace
Illicit drug use is prevalent among adults in the workforce (SAMHSA, 2014). Drug policy has developed under the assumption that drug use affects workplace performance and is accompanied by significant costs (Foster and Vaughan, 2005). In his Executive Order 12,564 (1986) creating a Drug-Free Federal Workplace, President Ronald Reagan stated, “Federal employees who use illegal drugs, on or off duty, tend to be less productive, less reliable, and prone to greater absenteeism than their fellow employees who do not use illegal drugs” (p. (Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - July 24, 2018 Category: Addiction Authors: Shrinidhi Subramaniam, August F. Holtyn, Brantley P. Jarvis, Mikhail N. Koffarnus, Jeannie S. Leoutsakos, Kenneth Silverman Tags: Full length article Source Type: research
