Issue Information
Diseases of the Esophagus,Volume 29, Issue 8, Page 895-896, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

Recommendations for neoadjuvant pathologic staging (ypTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
Diseases of the Esophagus,Volume 29, Issue 8, Page 906-912, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

Recommendations for pathologic staging (pTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
Diseases of the Esophagus,Volume 29, Issue 8, Page 897-905, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

Recommendations for clinical staging (cTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
Diseases of the Esophagus,Volume 29, Issue 8, Page 913-919, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

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Diseases of the Esophagus,Volume 29, Issue 8, Page 895-896, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

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Diseases of the Esophagus,Volume 29, Issue 8, Page 906-912, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

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Diseases of the Esophagus,Volume 29, Issue 8, Page 897-905, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

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Diseases of the Esophagus,Volume 29, Issue 8, Page 913-919, November/December 2016. (Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - December 1, 2016 Category: Gastroenterology Source Type: research

Recommendations for clinical staging (cTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
We report analytic and consensus processes that produced recommendations for clinical stage groups (cTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition. The Worldwide Esophageal Cancer Collaboration (WECC) provided data on 22,123 clinically staged patients with epithelial esophageal cancers. Risk‐adjusted survival for each patient was developed using random survival forest analysis from which (1) data‐driven clinical stage groups were identified wherein survival decreased monotonically and was distinctive between and homogeneous within groups and (2) data‐driv...
Source: Diseases of the Esophagus - November 30, 2016 Category: Gastroenterology Authors: Thomas W. Rice, Hemant Ishwaran, Eugene H. Blackstone, Wayne L. Hofstetter, David P. Kelsen, Carolyn Apperson ‐Hansen, Tags: WECCS Manuscripts Source Type: research

Recommendations for neoadjuvant pathologic staging (ypTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
We report analytic and consensus processes that produced recommendations for neoadjuvant pathologic stage groups (ypTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition. The Worldwide Esophageal Cancer Collaboration provided data for 22,654 patients with epithelial esophageal cancers; 7,773 had pathologic assessment after neoadjuvant therapy. Risk‐adjusted survival for each patient was developed. Random forest analysis identified data‐driven neoadjuvant pathologic stage groups wherein survival decreased monotonically with increasing group, was distinctive between ...
Source: Diseases of the Esophagus - November 30, 2016 Category: Gastroenterology Authors: Thomas W. Rice, Hemant Ishwaran, David P. Kelsen, Wayne L. Hofstetter, Carolyn Apperson ‐Hansen, Eugene H. Blackstone, Tags: WECCS Manuscripts Source Type: research

Recommendations for pathologic staging (pTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals
We report analytic and consensus processes that produced recommendations for pathologic stage groups (pTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition. The Worldwide Esophageal Cancer Collaboration provided data for 22,654 patients with epithelial esophageal cancers; 13,300 without preoperative therapy had pathologic assessment after esophagectomy or endoscopic treatment. Risk‐adjusted survival for each patient was developed using random survival forest analysis to identify data‐driven pathologic stage groups wherein survival decreased monotonically with incr...
Source: Diseases of the Esophagus - November 30, 2016 Category: Gastroenterology Authors: T. W. Rice, H. Ishwaran, W. L. Hofstetter, D. P. Kelsen, C. Apperson ‐Hansen, E. H. Blackstone, Tags: WECCS Manuscripts Source Type: research

Issue Information
(Source: Diseases of the Esophagus)
Source: Diseases of the Esophagus - November 30, 2016 Category: Gastroenterology Tags: Issue Information Source Type: research

Venous thromboembolism in patients with esophageal or gastric cancer undergoing neoadjuvant chemotherapy
Summary There is a well‐established link between cancer and venous thromboembolism (VTE), and patients receiving chemotherapy for esophageal or gastric cancer appear at high risk of developing VTE. The incidence of VTE in the neoadjuvant setting in these patients is poorly understood, as is the role for thromboprophylaxis during neoadjuvant chemotherapy. A PubMed search was conducted using a combination of terms including; esophageal & gastric cancer, deep venous thrombosis (DVT), VTE, neoadjuvant, chemotherapy and chemoradiotherapy. One hundred and fifty‐four articles were retrieved and a narrative review was cond...
Source: Diseases of the Esophagus - November 22, 2016 Category: Gastroenterology Authors: M. Marshall ‐Webb, T. Bright, T. Price, S. K. Thompson, D. I. Watson Tags: Original Article Source Type: research

Survival outcomes of consolidation chemoradiotherapy in esophageal cancer patients who achieve clinical complete response but refuse surgery after neoadjuvant chemoradiotherapy
This study was performed to investigate the survival outcomes of these patients. Between 2000 and 2012, we identified 190 patients with resectable esophageal squamous cell carcinoma (ESCC) who did not proceed to surgery following nCRT. Subjects who had a clinical complete response (cCR) and were medically fit for surgery were deemed eligible. Survival rates, recurrence patterns, and risk factors for recurrence served as the main outcome measures. The study cohort consisted of 73 patients (67 males and 6 females; mean age: 61.3 years). The 5‐year overall survival was 39.6% (median survival time: 46.77 months). Cancer recu...
Source: Diseases of the Esophagus - November 22, 2016 Category: Gastroenterology Authors: Hsin ‐Yueh Fang, Yin‐Kai Chao, Hsien‐Kun Chang, Chen‐Kan Tseng, Yun‐Hen Liu Tags: Original Article Source Type: research

Tagging polymorphisms of methyl ‐CpG binding domain 4 and gastric cardiac adenocarcinoma risk in a Chinese population
Summary Potential effects of genetic factors on carcinogenesis of gastric cardiac adenocarcinoma (GCA) may exist. The present experiment specifically evaluated the genetic influence of single nucleotide in methyl‐CpG binding domain 4 (MBD4) on GCA tumorigenesis. A case–control experiment based on hospital recruited 330 GCA patients and 608 non‐cancer patients was carried out. We employed ligation detection reaction method to detect the genotypes. The results revealed that MBD4 rs3138373, rs2005618, and rs3138355 mutations had no significant association with the risk of GCA. However, a lower risk of GCA presented in m...
Source: Diseases of the Esophagus - November 20, 2016 Category: Gastroenterology Authors: Xu Wang, Changqing Dong, Jun Yin, Weifeng Tang, Zhenya Shen Tags: Original Manuscript Source Type: research