Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis
Dis Markers. 2023 Nov 1;2023:9013756. doi: 10.1155/2023/9013756. eCollection 2023.ABSTRACTDupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated with DUP were analysed by metabolome analysis using gas chromatography-mass spectrometry. Total 148 metabolites were detected, and the rela...
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Shoko Miyamoto Yasutomo Imai Masako Matsutani Makoto Nagai Kiyofumi Yamanishi Nobuo Kanazawa Shin Nishiumi Source Type: research
Retracted: Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders
Dis Markers. 2023 Nov 1;2023:9792838. doi: 10.1155/2023/9792838. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/9116502.].PMID:37946798 | PMC:PMC10632054 | DOI:10.1155/2023/9792838 (Source: Disease Markers)
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis
Dis Markers. 2023 Nov 1;2023:9013756. doi: 10.1155/2023/9013756. eCollection 2023.ABSTRACTDupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated with DUP were analysed by metabolome analysis using gas chromatography-mass spectrometry. Total 148 metabolites were detected, and the rela...
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Shoko Miyamoto Yasutomo Imai Masako Matsutani Makoto Nagai Kiyofumi Yamanishi Nobuo Kanazawa Shin Nishiumi Source Type: research
Retracted: Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders
Dis Markers. 2023 Nov 1;2023:9792838. doi: 10.1155/2023/9792838. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/9116502.].PMID:37946798 | PMC:PMC10632054 | DOI:10.1155/2023/9792838 (Source: Disease Markers)
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis
Dis Markers. 2023 Nov 1;2023:9013756. doi: 10.1155/2023/9013756. eCollection 2023.ABSTRACTDupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated with DUP were analysed by metabolome analysis using gas chromatography-mass spectrometry. Total 148 metabolites were detected, and the rela...
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Shoko Miyamoto Yasutomo Imai Masako Matsutani Makoto Nagai Kiyofumi Yamanishi Nobuo Kanazawa Shin Nishiumi Source Type: research
Retracted: Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders
Dis Markers. 2023 Nov 1;2023:9792838. doi: 10.1155/2023/9792838. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/9116502.].PMID:37946798 | PMC:PMC10632054 | DOI:10.1155/2023/9792838 (Source: Disease Markers)
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis
Dis Markers. 2023 Nov 1;2023:9013756. doi: 10.1155/2023/9013756. eCollection 2023.ABSTRACTDupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated with DUP were analysed by metabolome analysis using gas chromatography-mass spectrometry. Total 148 metabolites were detected, and the rela...
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Shoko Miyamoto Yasutomo Imai Masako Matsutani Makoto Nagai Kiyofumi Yamanishi Nobuo Kanazawa Shin Nishiumi Source Type: research
Retracted: Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders
Dis Markers. 2023 Nov 1;2023:9792838. doi: 10.1155/2023/9792838. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/9116502.].PMID:37946798 | PMC:PMC10632054 | DOI:10.1155/2023/9792838 (Source: Disease Markers)
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis
Dis Markers. 2023 Nov 1;2023:9013756. doi: 10.1155/2023/9013756. eCollection 2023.ABSTRACTDupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated with DUP were analysed by metabolome analysis using gas chromatography-mass spectrometry. Total 148 metabolites were detected, and the rela...
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Shoko Miyamoto Yasutomo Imai Masako Matsutani Makoto Nagai Kiyofumi Yamanishi Nobuo Kanazawa Shin Nishiumi Source Type: research
Retracted: Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders
Dis Markers. 2023 Nov 1;2023:9792838. doi: 10.1155/2023/9792838. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/9116502.].PMID:37946798 | PMC:PMC10632054 | DOI:10.1155/2023/9792838 (Source: Disease Markers)
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis
Dis Markers. 2023 Nov 1;2023:9013756. doi: 10.1155/2023/9013756. eCollection 2023.ABSTRACTDupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated with DUP were analysed by metabolome analysis using gas chromatography-mass spectrometry. Total 148 metabolites were detected, and the rela...
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Shoko Miyamoto Yasutomo Imai Masako Matsutani Makoto Nagai Kiyofumi Yamanishi Nobuo Kanazawa Shin Nishiumi Source Type: research
Retracted: Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders
Dis Markers. 2023 Nov 1;2023:9792838. doi: 10.1155/2023/9792838. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/9116502.].PMID:37946798 | PMC:PMC10632054 | DOI:10.1155/2023/9792838 (Source: Disease Markers)
Source: Disease Markers - November 10, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
Meta-Analysis of Assessment of Total Oxidative Stress and Total Antioxidant Capacity in Patients with Periodontitis
CONCLUSIONS: The present meta-analysis showed significantly higher TOS and lower TAC in periodontitis, reflecting the elevated oxidative stress level than the control group. Clinical Relevance. Scientific rationale for the study: The imbalance between oxidants and antioxidants (oxidative stress (OS)) plays a critical role in the onset and progression of periodontitis; the assessment of the relationship between OS-related biomarkers in regional samples and systemic samples of patients with periodontitis helps us to evaluate the periodontal disease progression. The OS biomarker levels can be used to assess periodontal diseas...
Source: Disease Markers - November 8, 2023 Category: Laboratory Medicine Authors: Khadijah Mohideen Krithika Chandrasekaran Harsha Veeraraghavan Shahul Hameed Faizee Safal Dhungel Snehashish Ghosh Source Type: research
Retracted: Bioinformatics Analysis Identifies < em > ASCL1 < /em > as the Key Transcription Factor in Hepatocellular Carcinoma Progression
Dis Markers. 2023 Oct 18;2023:9894804. doi: 10.1155/2023/9894804. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2023/3560340.].PMID:37886108 | PMC:PMC10599856 | DOI:10.1155/2023/9894804 (Source: Disease Markers)
Source: Disease Markers - October 27, 2023 Category: Laboratory Medicine Authors: Disease Markers Source Type: research
