Limb salvage in diabetic patients with no-option critical limb ischemia: outcomes of a specialized center experience.
Conclusions: The application of dedicated and standardized strategies permitted limb salvage in one-third of patients with no-option CLI. Patients with stable lesions limited to the forefoot and without ischaemic pain had a greater probability to successfully receive conservative treatments. Limb salvage was associated with subsequent higher one-year survival. PMID: 31839898 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - December 18, 2019 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Serum vitamin D and diabetic foot complications.
Conclusion: We found various lower extremity complications to be associated with low serum vitamin D including PAD, DFI, and DFU. While other studies have questioned the role of vitamin D and CN, we were unable to identify any significant difference between diabetic patients with and without Charcot neuroarthropathy. Level of evidence: Level 2. PMID: 30815231 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - March 5, 2019 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Diabetes-related foot disorders among adult Ghanaians.
Conclusions: We have found a trend towards an increased incidence of diabetic foot in an outpatient tertiary diabetes setting in Ghana. Systemic and individual-level factors aimed at preventive foot screening as well as vascular risk factor control should be intensified in diabetic patients in Ghana and other LMICs. Abbreviations: BMI: Body Mass Index, BP: Blood Pressure, CI: Confidence Interval, HR: Hazard Ratio, HbA1c: Glycated Hemoglobin, PAD: Peripheral Arterial Disease, NCDs: Non Communicable Disease, SSA: Sub Saharan Africa. PMID: 30202507 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - September 12, 2018 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Cost-effectiveness analysis of the human recombinant epidermal growth factor in the management of patients with diabetic foot ulcers.
Conclusions: The intra- and perilesional application of rhEGF is a more effective therapeutic option than conventional therapy in the treatment of patients with Wagner's 3 or 4 diabetic foot ulcers and is cost-effective, taking as an outcome the QALYs for Colombia from the perspective of the health system. PMID: 29963295 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - July 4, 2018 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Diabetic foot ulcer outcomes from a podiatry led tertiary service in Kuwait.
Conclusions: The incidence of new DFUs in our tertiary clinic is 3.4%. The incidence of diabetic foot ulceration, days to heal, healing rate and the risk factors influencing healing are in accordance with other multidisciplinary facilities with podiatry input. PMID: 29868165 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - June 7, 2018 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Follow up of MRI bone marrow edema in the treated diabetic Charcot foot - a review of patient charts.
Conclusion: EESC on MRI disappear in response to prolonged offloading and immobilizing treatment; however, physiologic as well as pathologic fluctuations of posttraumatic EESC have to be considered when interpreting the MR images. Conventional MRI is useful for surveillance of active-stage Charcot foot recovery. PMID: 29713425 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - May 2, 2018 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Building a scalable diabetic limb preservation program: four steps to success.
We describe four key components for a successful program that, developed sequentially with temporal overlap, can allow the program to scale. The first component includes establishment of a 'hot foot line' for urgent emergency department/inpatient referral. The second includes development of a wound-healing clinic to address outpatient care through to remission. The third component focuses on the diabetic foot in remission to maximize ulcer-free days following healing. The fourth and final component focuses on implementation of local and widespread screening clinics to identify and triage patients into appropriate therapeut...
Source: Diabetic Foot and Ankle - April 28, 2018 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

The abrupt temperature changes in the plantar skin thermogram of the diabetic patient: looking in to prevent the insidious ulcers.
Conclusion: A diabetic patient, with an asymmetric thermogram, as physiological interpretation of the thermoregulation, may indicate a decrease of the blood supply, which may be corroborated by vascular ultrasound. The regions of abrupt temperature change, cold or hot spots, may correspond to ischaemic or inflammatory processes. PMID: 29410772 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - February 9, 2018 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Is surgical debridement necessary in the diabetic foot treated with photodynamic therapy?
Conclusion: Our data indicates that debridement is not necessary in the treatment of diabetic foot in patients that have enough peripheral arterial perfusion. In addition, we reproduced previous studies confirming that PDT is an efficient, safe, simple and affordable treatment method for the diabetic foot. PMID: 29057063 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - October 25, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Beyond dichotomous thinking: a process perspective on diabetic foot disease.
Conclusions: The process perspective on the DF seems suitable for understanding inadequate patient behaviors not easily understood with a dichotomous perspective on DF disease, opening up new avenues for clinical practice and research to help patients live a life with long remission phases, few relapses, and a high quality of life. PMID: 29057064 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - October 25, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Nerve decompression and neuropathy complications in diabetes: Are attitudes discordant with evidence?
Authors: Nickerson DS Abstract External neurolysis of the nerve at fibro-osseous tunnels has been proprosed to treat or prevent signs, symptoms, and complications in the lower extremity of diabetes patients with sensorimotor polyneuropathy. Nerve decompression is justified in the presence of symptomatic compressed nerves in the several fibro-osseous tunnels of the extremities, which are known to be frequent in diabetes. Quite a body of literature has accumulated reporting results after such nerve decompression in the leg, describing pain relief and sensibility improvement, as well as balance recovery, diab...
Source: Diabetic Foot and Ankle - September 30, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Clinical and surgical characteristics of infected diabetic foot ulcers in a tertiary hospital of Mexico.
Conclusions: Therefore, an effective antibiotic treatment and an education of the patient on the adequate care of their lesions are essential in increasing the welfare of patients, especially when they have a low level of education. PMID: 28904744 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - September 16, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

The thermoregulation of healthy individuals, overweight-obese, and diabetic from the plantar skin thermogram: a clue to predict the diabetic foot.
Conclusions: An asymmetric thermogram of the plantar skin of diabetic individuals, where one foot is hotter than the other, may mean that the coldest foot is losing the capacity to communicate properly with the central nervous system and/or that vasoconstriction/vasodilatation is having problems in regulating the passing of blood through the vessels. Thus, the asymmetric thermograms of diabetic patients, and particularly those coldest regions of foot are of interest, because of the reduction of the local autonomic sensing and the lack of achieving properly the passing of the blood. PMID: 28839522 [PubMed] (Source: ...
Source: Diabetic Foot and Ankle - August 27, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

An innovative sealed shoe to off-load and heal diabetic forefoot ulcers - a feasibility study.
Conclusions: Sealing a therapeutic shoe is a feasible way to off-load and heal forefoot ulcers. A controlled trial is needed to compare the effectiveness and safety of a sealed shoe to other non-removable devices. PMID: 28804593 [PubMed] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - August 16, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research

Clinical profile and outcome of diabetic foot ulcer, a view from tertiary care hospital in Semarang, Indonesia.
Conclusions: Diabetic foot problems constitute a source of morbidity, a reason for LEA surgery as well as being a cause of death among patients with diabetes mellitus. PMID: 28649296 [PubMed - in process] (Source: Diabetic Foot and Ankle)
Source: Diabetic Foot and Ankle - June 28, 2017 Category: Endocrinology Tags: Diabet Foot Ankle Source Type: research