[Sugar content in non-alcoholic beverages and dietary recemmendations for children and adolescents].
CONCLUSIONS: Significant monosaccharides and sucrose content in the tested non-alcohollic beverages tends to claim that their manufacturers should be obliged to place warnings on the labels addressed to patients suffering from disorders of carbohydrate metabolism. Educational programs for children and adolescents with diabetes should include information about the content of a large amount of sugars in fruit products: fruit juices, fruit drinks and fruit nectar. PMID: 26615582 [PubMed - in process] (Source: Diabetes Metab)
Source: Diabetes Metab - December 2, 2015 Category: Endocrinology Authors: Bilek M, Rybakowa M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Insulin-like growth factor-1 (IGF-1) - structure and the role in the human body].
Abstract In the recent years, managed to broadly explore the structure and role of insulin-like growth factors type 1 and 2 (IGF1 I 2). They belong to the structure of polypeptide hormones homologous to proinsulin. They are characterized by a wide range of activities. IGF-1 is a key mediator of most tissue effects of growth hormone (GH). In addition to effects on growth processes of the body, is also an important factor for cell homeostasis, is subject to both endocrine and tissue-specific auto- and paracrine regulation. In this paper, the current, general knowledge on the structure, function and mechanism...
Source: Diabetes Metab - December 2, 2015 Category: Endocrinology Authors: Filus A, Zdrojewicz Z Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Yeast-like fungi in the gastrointestinal tract in children and adolescents with diabetes type 1].
Abstract In recent years the frequency of fungal infections in human populations has increased considerably. The most common type offungus attacking the human organism is Candida albicans. Yeast-like fungi occur naturally in the oral cavity, intestines, vagina, or skin, however in amounts not dangerous to human health. The studies so far have shown that patients with diabetes type 1 (T1DM) to a large degree are exposed to complications related to fungal infections. A substantial growth of fungi observed in diabetic patients may unfavorably affect metabolic compensation, and lead to increased demand for ins...
Source: Diabetes Metab - December 2, 2015 Category: Endocrinology Authors: Kowalewska B, Kawko M, Zorena K, Myśliwiec M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Response to low dose indomethacin in two children with nephrogenic diabetes insipidus.
Abstract Two children with nephrogenic diabetes insipidus (NDI) were treated with oral indomethacin (0.75-1.2 mg/kg/day) three times a day for a mean duration of 3 yrs. Remission occurred in both patients in terms of achieving a normal fluid balance and body growth and the drug was withdrawn in one patient after 2 yrs. The treatment was well tolerated and no side effects were noted. The mean duration of follow-up was 6.5 yrs. These long-term observations of a favourable response to low dose indomethacin in 2 children with NDI need to be tested on larger number of patients. PMID: 26615585 [PubMed -...
Source: Diabetes Metab - December 2, 2015 Category: Endocrinology Authors: Dayal D, Verma Attri S, Kumar Bhalla A, Kumar R Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Trends in mortality due to diabetes in Brazil, 1996-2011.
CONCLUSION: Mortality due to diabetes declined in Brazil from 1996 to 2011, minimally in men and considerably in women. The lesser declines in recent years may reflect the increasing prevalence of diabetes, and suggest that current efforts to prevent diabetes and minimize the impact of its complications need to be reinforced to ensure that declines will continue. PMID: 26617678 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - December 2, 2015 Category: Endocrinology Authors: Schmidt MI, Duncan BB, Ishitani L, da Conceição Franco G, de Abreu DM, Lana GC, França E Tags: Diabetol Metab Syndr Source Type: research

Effects on lipid profile of supplementation with vitamin D in type 2 diabetic patients with vitamin D deficiency.
CONCLUSIONS: Correction of vitamin D deficiency in type 2 diabetic patients decreases total cholesterol. Our results do not rule out reductions in LDL cholesterol, non-HDL cholesterol and triglycerides. PMID: 26623001 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - December 1, 2015 Category: Endocrinology Authors: Ramiro-Lozano JM, Calvo-Romero JM Tags: Ther Adv Endocrinol Metab Source Type: research

Vitamin D as a risk factor for premature atherosclerosis in patients with type 2 diabetes.
CONCLUSIONS: Decreased vitamin D levels in patients with diabetes lead to increased CIMT. The absence of a statistically significance difference in lipid profile between increased and normal CIMT groups raises the possibility of underlying causes for atherosclerosis in patients with diabetes other than dyslipidemia. PMID: 26623002 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - December 1, 2015 Category: Endocrinology Authors: Hamdy Al-Said N, Abd El Ghaffar Mohamed N, Salam RF, Fawzy MW Tags: Ther Adv Endocrinol Metab Source Type: research

Comparison of conventional risk factors in middle-aged versus elderly diabetic and nondiabetic patients with myocardial infarction: prediction with decision-analytic model.
CONCLUSIONS: The CART model is capable of symbolizing interpretable clinical data for confirming and better prediction of MI occurrence in clinic or in hospital. Therefore, predictor variables in pattern could affect the outcome based on age group variable. Hyperglycemia, hypertension, hyperlipidemia and hyperuricemia were serious predictors for occurrence of MI in diabetics. PMID: 26623003 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - December 1, 2015 Category: Endocrinology Authors: Mahmoodi MR, Baneshi MR, Rastegari A Tags: Ther Adv Endocrinol Metab Source Type: research

Oral Presentation.
Authors: PMID: 26608948 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - November 29, 2015 Category: Endocrinology Tags: Diabetes Metab Res Rev Source Type: research

Infertility and Reproductive Function in Patients with Congenital Adrenal Hyperplasia: Pathophysiology, Advances in Management, and Recent Outcomes.
Abstract Individuals with congenital adrenal hyperplasia have reduced fertility. However, reproductive outcomes have improved over the years. This review provides an update on the multiple pathologic processes that contribute to reduced fertility in both sexes, from alterations of the hypothalamic-pituitary-gonadal axis to the direct effect on gonadal function by elevated circulating adrenal androgens. In addition, elevated serum progesterone concentrations may hinder ovulation and embryo implantation in women, whereas in men testicular adrenal rest tumors can be a major cause of infertility. Suppression o...
Source: Diabetes Metab - November 20, 2015 Category: Endocrinology Authors: Lekarev O, Lin-Su K, Vogiatzi MG Tags: Endocrinol Metab Clin North Am Source Type: research

Reproductive Issues in Women with Turner Syndrome.
Abstract Turner syndrome is one of the most common chromosomal abnormalities affecting female infants. The severity of clinical manifestations varies and it affects multiple organ systems. Women with Turner syndrome have a 3-fold increase in mortality, which becomes even more pronounced in pregnancy. Reproductive options include adoption or surrogacy, assisted reproductive techniques, and in rare cases spontaneous pregnancy. Risks for women with Turner syndrome during pregnancy include aortic disorders, hepatic disease, thyroid disease, type 2 diabetes, and cesarean section delivery. Providers must be fami...
Source: Diabetes Metab - November 20, 2015 Category: Endocrinology Authors: Folsom LJ, Fuqua JS Tags: Endocrinol Metab Clin North Am Source Type: research

Reproductive Endocrinology.
PMID: 26568499 [PubMed - in process] (Source: Diabetes Metab)
Source: Diabetes Metab - November 20, 2015 Category: Endocrinology Authors: LeRoith D Tags: Endocrinol Metab Clin North Am Source Type: research

Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies.
Abstract Obesity is gaining acceptance as a serious primary health burden that impairs the quality of life because of its associated complications, including diabetes, cardiovascular diseases, cancer, asthma, sleep disorders, hepatic dysfunction, renal dysfunction, and infertility. It is a complex metabolic disorder with a multifactorial origin. Growing evidence suggests that oxidative stress plays a role as the critical factor linking obesity with its associated complications. Obesity per se can induce systemic oxidative stress through various biochemical mechanisms, such as superoxide generation from NAD...
Source: Diabetes Metab - November 20, 2015 Category: Endocrinology Authors: Manna P, Jain SK Tags: Metab Syndr Relat Disord Source Type: research

Expression of REG Iα gene in type 2 diabetics in Pakistan.
CONCLUSION: REG Iα may be used as a marker/predictor of type 2 diabetes especially in the early stages of the disease. PMID: 26568772 [PubMed] (Source: Diabetes Metab)
Source: Diabetes Metab - November 20, 2015 Category: Endocrinology Authors: Uppal SS, Naveed AK, Baig S, Chaudhry B Tags: Diabetol Metab Syndr Source Type: research

Endocrine abnormalities in ring chromosome 11: a case report and review of the literature.
Abstract Ring chromosomes (RCs) are uncommon cytogenetic findings, and RC11 has only been described in 19 cases in the literature. Endocrine abnormalities associated with RC11 were reported for two of these cases. The clinical features of RC11 can result from an alteration in the structure of the genetic material, ring instability, mosaicism, and various extents of genetic material loss. We herein describe a case of RC11 with clinical features of 11q-syndrome and endocrine abnormalities that have not yet been reported. A 20-year-old female patient had facial dysmorphism, short stature, psychomotor developm...
Source: Diabetes Metab - November 20, 2015 Category: Endocrinology Authors: Lange R, Von Linsingen C, Mata F, Moraes AB, Arruda M, Vieira Neto L Tags: Endocrinol Diabetes Metab Case Rep Source Type: research