Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study
CONCLUSIONS
The high rates of DPN among youth with diabetes are a cause of concern and suggest a need for early screening and better risk factor management. Interventions in youth that address poor glycemic control and dyslipidemia may prevent or delay debilitating neuropathic complications. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Jaiswal, M.; Divers, J.; Dabelea, D.; Isom, S.; Bell, R. A.; Martin, C. L.; Pettitt, D. J.; Saydah, S.; Pihoker, C.; Standiford, D. A.; Dolan, L. M.; Marcovina, S.; Linder, B.; Liese, A. D.; Pop-Busui, R.; Feldman, E. L. Tags: Complications-Neuropathy Pathophysiology/Complications Source Type: research
A Team-Based Online Game Improves Blood Glucose Control in Veterans With Type 2 Diabetes: A Randomized Controlled Trial
CONCLUSIONS
Patients with diabetes who were randomized to an online game delivering DSME demonstrated sustained and meaningful HbA1c improvements. Among patients with poorly controlled diabetes, the DSME game reduced HbA1c by a magnitude comparable to starting a new diabetes medication. Online games may be a scalable approach to improve outcomes among geographically dispersed patients with diabetes and other chronic diseases. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Kerfoot, B. P.; Gagnon, D. R.; McMahon, G. T.; Orlander, J. D.; Kurgansky, K. E.; Conlin, P. R. Tags: Diabetes Education Emerging Technologies and Therapeutics Source Type: research
Visit-to-Visit Variations in Fasting Plasma Glucose and HbA1c Associated With an Increased Risk of Alzheimer Disease: Taiwan Diabetes Study
CONCLUSIONS
FPG CV and HbA1c CV are independently associated with AD. The associations between glycemic variability and AD demonstrated in this study suggest a linked pathophysiological mechanism, which is worthy of further investigation. Further research is required to confirm our results and to evaluate whether FPG CV and HbA1c CV can be valuable therapeutic targets for patients with T2DM at risk. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Li, T.-C.; Yang, C.-P.; Tseng, S.-T.; Li, C.-I.; Liu, C.-S.; Lin, W.-Y.; Hwang, K.-L.; Yang, S.-Y.; Chiang, J.-H.; Lin, C.-C. Tags: Epidemiology-Other Epidemiology/Health Services Research Source Type: research
Cardiac Stress and Inflammatory Markers as Predictors of Heart Failure in Patients With Type 2 Diabetes: The ADVANCE Trial
CONCLUSIONS
Only NT-proBNP strongly and consistently improved the prediction of heart failure in patients with type 2 diabetes beyond a wide range of clinical risk factors and biomarkers. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Ohkuma, T.; Jun, M.; Woodward, M.; Zoungas, S.; Cooper, M. E.; Grobbee, D. E.; Hamet, P.; Mancia, G.; Williams, B.; Welsh, P.; Sattar, N.; Shaw, J. E.; Rahimi, K.; Chalmers, J.; on behalf of the ADVANCE Collaborative Group Tags: Epidemiology/Health Services Research Source Type: research
Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study
CONCLUSIONS
These results show clear differences in the initiation of autoimmunity according to genetic factors and environmental exposures that give rise to IAA or GADA as the first appearing indication of autoimmunity. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Krischer, J. P.; Lynch, K. F.; Lernmark, A.; Hagopian, W. A.; Rewers, M. J.; She, J.-X.; Toppari, J.; Ziegler, A.-G.; Akolkar, B.; the TEDDY Study Group Tags: Epidemiology-Type 1 Diabetes Epidemiology/Health Services Research Source Type: research
Hemoglobin A1c Variability Predicts Symptoms of Depression in Elderly Individuals With Type 2 Diabetes
CONCLUSIONS
Variability in glycemic control is associated with more depressive symptoms. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Ravona-Springer, R.; Heymann, A.; Schmeidler, J.; Moshier, E.; Guerrero-Berroa, E.; Soleimani, L.; Sano, M.; Leroith, D.; Preiss, R.; Tzukran, R.; Silverman, J. M.; Beeri, M. S. Tags: Epidemiology-Diabetes Complications Epidemiology/Health Services Research Source Type: research
Poor Reliability and Poor Adherence to Self-Monitoring of Blood Glucose Are Common in Women With Gestational Diabetes Mellitus and May Be Associated With Poor Pregnancy Outcomes
CONCLUSIONS
Although women with GDM are considered to be highly motivated, SMBG adherence and reliability are of concern and may be associated with poor gestational prognosis, suggesting that caregivers should systematically check the glucose meter memory to improve GDM management. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Cosson, E.; Baz, B.; Gary, F.; Pharisien, I.; Nguyen, M. T.; Sandre-Banon, D.; Jaber, Y.; Cussac-Pillegand, C.; Banu, I.; Carbillon, L.; Valensi, P. Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
Improvement in Glycemic Control of Type 2 Diabetes After Successful Treatment of Hepatitis C Virus
CONCLUSIONS
DAA-based eradication of HCV is associated with improved glycemic control in patients with diabetes as evidenced by decreased mean HbA1c and decreased insulin use. These endocrine benefits of SVR provide additional justification for considering antiviral treatment in all patients with diabetes. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Hum, J.; Jou, J. H.; Green, P. K.; Berry, K.; Lundblad, J.; Hettinger, B. D.; Chang, M.; Ioannou, G. N. Tags: Integrated Physiology-Liver Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
My Child Is Islet Autoantibody Positive: Impact on Parental Anxiety
CONCLUSIONS
Infant genetic screening for type 1 diabetes raises parent anxiety when the child is at increased risk, but anxiety dissipates over time in cases of repeated IA– results. IA+ results heighten parent anxiety, and parents faced with two or more types of IA+ results may experience considerable anxiety for longer periods. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Johnson, S. B.; Lynch, K. F.; Roth, R.; Schatz, D.; the TEDDY Study Group Tags: Psychosocial, Behavioral Medicine Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
Diabetes in a Large Dementia Cohort: Clinical Characteristics and Treatment From the Swedish Dementia Registry
CONCLUSIONS
Patients with diabetes were younger at dementia diagnosis and obtained less dementia medication for Alzheimer disease, suggesting less optimal dementia treatment. Future research should evaluate survival and differences in metabolic profile in patients with diabetes and different dementia disorders. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Secnik, J.; Cermakova, P.; Fereshtehnejad, S.-M.; Dannberg, P.; Johnell, K.; Fastbom, J.; Winblad, B.; Eriksdotter, M.; Religa, D. Tags: Epidemiology-Aging Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
George Alberti: A Myriad of Contributions to Diabetes and Beyond
(Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Home, P. Tags: Profiles in Progress Source Type: research
The War Is Not Yet Won
(Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Young, L. A.; Buse, J. B. Tags: Epidemiology-Other Commentary Source Type: research
Composite Primary End Points in Cardiovascular Outcomes Trials Involving Type 2 Diabetes Patients: Should Unstable Angina Be Included in the Primary End Point?
Reductions in cardiovascular (CV) outcomes in recently reported trials, along with the recent approval by the U.S. Food and Drug Administration of an additional indication for empagliflozin to reduce the risk of CV death in type 2 diabetes patients with evidence of CV disease, have renewed interest in CV outcome trials (CVOTs) of glucose-lowering drugs. Composite end points are a pragmatic necessity in CVOTs to ensure that sample size and duration of follow-up remain reasonable. Combining clinical outcomes into a composite end point increases the numbers of events ascertained and thus statistical power and precision. Histo...
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Marx, N.; McGuire, D. K.; Perkovic, V.; Woerle, H.-J.; Broedl, U. C.; von Eynatten, M.; George, J. T.; Rosenstock, J. Tags: Perspectives in Care Source Type: research
Declines in the Incidence of Diabetes in the U.S.--Real Progress or Artifact?
We present and discuss data that suggest improved detection and changes in screening and diagnostic practices may have resulted in the depletion of the "susceptible population." Providing this context for the recent declines in new diabetes diagnoses observed in national data is critical to help avoid misinterpretation. We argue that it is premature to declare victory against the epidemic of diabetes in the U.S. and discuss how we might better focus current public health efforts, including a specific emphasis to address prediabetes. (Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Selvin, E.; Ali, M. K. Tags: Perspectives in Care Source Type: research
In This Issue of Diabetes Care
(Source: Diabetes Care)
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Tags: In This Issue Source Type: research
