Molecular mechanisms of trehalose in modulating glucose homeostasis in diabetes
Publication date: Available online 23 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Habib Yaribeygi, Alijan Yaribeygi, Thozhukat Sathyapalan, Amirhossein SahebkarAbstractDiabetes mellitus is the most prevalent metabolic disorder contributing to significant morbidity and mortality in humans. Many preventative and therapeutic agents have been developed for normalizing glycemic profile in patients with diabetes. In addition to various pharmacologic strategies, many non-pharmacological agents have also been suggested to improve glycemic control in patients with diabetes. Trehalose...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 23, 2019 Category: Endocrinology Source Type: research

Subclinical vascular disease in patients with diabetes is associated with insulin resistance
Publication date: Available online 23 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): María M. Adeva-Andany, Raquel Funcasta-Calderón, Carlos Fernández-Fernández, Eva Ameneiros-Rodríguez, Alberto Domínguez-MonteroAbstractPatients with diabetes experience increased cardiovascular risk that is not fully explained by deficient glycemic control or traditional cardiovascular risk factors such as smoking and hypercholesterolemia. Asymptomatic patients with diabetes show structural and functional vascular damage that includes impaired vasodilat...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 23, 2019 Category: Endocrinology Source Type: research

Complications of type 2 diabetes in Iranian population: An updated systematic review and meta-analysis
Publication date: Available online 23 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Yousef Moradi, Hamid Reza Baradaran, Shirin Djalalinia, Ahdieh Chinekesh, Mohamad Ebrahim Khamseh, Maryam Dastoorpoor, Amir-Babak Sioofy-Khojine, Lotfollah Saed, Mostafa QorbaniAbstractComplications among patients with type 2 diabetes mellitus (T2DM) have increased dramatically through two past decades. Thus, the aim of this updated systematic review and meta-analysis was to t estimate the pooled prevalence of T2DM complications in Iranian patients. Using Medical Subject Headings terms, Emtree,...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 23, 2019 Category: Endocrinology Source Type: research

Effectiveness of cognitive-behavioral therapy on nutrition improvement and weight of overweight and obese adolescents: A randomized controlled trial
Publication date: Available online 22 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Seyedeh Fatemeh Miri, Maryam Javadi, Chung-Ying Lin, Mark D. Griffiths, Maria Björk, Amir H. PakpourAbstractAimTo assess the effectiveness of a cognitive-behavioral treatment (CBT) program on weight reduction among Iranian adolescents with overweight.MethodsUsing a randomized controlled trial design, 55 adolescents with overweight (mean [SD] age = 14.64 [1.69] years; zBMI = 2.18 [0.65]) were recruited in the CBT program and 55 in the treatment as usual (TAU; mean age = 14.88 [1...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 22, 2019 Category: Endocrinology Source Type: research

The influence of diabetes and or periodontitis on inflammation and adiponectin level
ConclusionLocal inflammation such as periodontitis, elevated systemic inflammatory markers (TNF-α/IL-10 ratio). Meanwhile chronic hyperglycemia alter adipocytokines level. The changes of systemic inflammation among diabetic group had not been shown yet in this study since some antidiabetic and antilipid drugs possess anti-inflammtory effect. Age, WC and FBG correlated with severe periodontitis. Adiponectin, leptin, TNF-α and IL-10 levels did not correlated with severe periodontitis. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 22, 2019 Category: Endocrinology Source Type: research

Study of correlation between chronic stressor, biochemical markers and hematologic indices in Shahrekord Cohort Study: A population-based cross-sectional study
ConclusionThis study reported that the level of exposure to stressors was higher than that of other studies, and the results of this study are recommended to be used for screening and early detection of the consequences of exposure to chronic stressors, especially for the prevention of cardiovascular diseases. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 17, 2019 Category: Endocrinology Source Type: research

Evaluation of muscle mass in obesity, prediabetes and diabetes mellitus by different equations used for the measurement of muscle mass
Publication date: Available online 15 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Mustafa Reşat Dabak, Elif Sevinç, Sabah Tüzün, Emine Özel GünAbstractObjectiveInsulin resistance is one of risk factors for sarcopenia and there is no specific equation for the measurement of muscle mass. The present study aimed to evaluate muscle mass in the patients with obesity, prediabetes (PDM) and type 2 diabetes mellitus (DM) by different equations for the measurement of muscle mass.MethodsObese patients aged 18–65 years old, who presented between 2013 a...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 16, 2019 Category: Endocrinology Source Type: research

Strategies to ameliorate endothelial dysfunction associated with metabolic syndrome, where are we?
Publication date: Available online 14 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Sigfrid Casmir ShayoAbstractThere is a paucity of aggregated clinical trials on strategies of ameliorating endothelial dysfunction associated with Metabolic Syndrome (MS). We reviewed clinical trials conducted between 2008 and 2017, reporting on strategies of improving endothelial function in patients with MS. A comprehensive search of published articles by the Google Scholar and PubMed were carried out. Only studies involving non-invasive, objective measurement of endothelial function were inc...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 15, 2019 Category: Endocrinology Source Type: research

A health needs assessment of adults with diabetic foot disease in the US
Publication date: Available online 13 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Hanxu ShiAbstractIntroductionDiabetic foot disease has been considered as an important complication of diabetes mellitus. The main risk factor to cause diabetic foot disease is peripheral neuropathy. Diabetic foot disease usually started from diabetic foot ulceration, it would develop to diabetic foot infection and amputation even death when conducting the poor prognosis and management of diabetic foot ulceration. Despite this, incidence of diabetic foot disease is still increasing and is there...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 14, 2019 Category: Endocrinology Source Type: research

Efficacy and safety of the second generation basal insulin analogs in type 2 diabetes mellitus: A critical appraisal
Publication date: Available online 12 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Vargas-Uricoechea Hernando, Frias Juan Pablo (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 14, 2019 Category: Endocrinology Source Type: research

Effect of Sudarshan Kriya Yoga on anxiety, depression, and quality of life in people with type 2 diabetes: A pilot study in Kuwait
ConclusionResults indicate that SKY can be potentially beneficial for treating anxiety, insomnia, and depression associated in people with T2DM and in improving the quality of life in people with T2DM. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 9, 2019 Category: Endocrinology Source Type: research

A validation study of questionnaire towards mobile based health applications in uncontrolled diabetic population of India (South)
ConclusionThe final version of questionnaire was found to be statistically internally consistent, reproducible and reliable and could be used to assess the awareness and attitude of patients towards self-management of diabetes mellitus. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 8, 2019 Category: Endocrinology Source Type: research

The effect of glycemic control on salivary lipid peroxidation in type II diabetic patients
ConclusionEvaluation of salivary MDA levels could be useful in prediction of glycemic control. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 8, 2019 Category: Endocrinology Source Type: research

Change in insulin resistance, beta cell function, glucagon-like Peptide-1 and calcitonin levels two weeks after bariatric surgery
ConclusionsAt 2 weeks following bariatric surgery, hepatic insulin resistance decreased while beta cell function improved due to increase in postprandial GLP-1 level without any change in fasting calcitonin levels. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 8, 2019 Category: Endocrinology Source Type: research

Obesity an overview: Genetic conditions and recent developments in therapeutic interventions
Publication date: Available online 7 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Vikram Rao B. Vasanth Rao, Mayuren Vasanth Rao, Subrat Kumar BhattamisraAbstractObesity is a complex disorder that is linked to many coexisting disorders. Recent epidemiological data have suggested that the prevalence of obesity is at an all-time high, growing to be one of the world's biggest problems. There are several mechanisms on how individuals develop obesity which includes genetic and environmental factors. Not only does obesity contribute to other health issues but it also greatly affect...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 8, 2019 Category: Endocrinology Source Type: research

Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome
Publication date: Available online 7 May 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Shayaq Ul Abeer Rasool, Sairish Ashraf, Mudasar Nabi, Fouzia Rashid, Khalid Majid Fazili, Shajrul AminAbstractAimsPCOS is associated with various immediate and long term health complications. The aim of this study was to investigate the association of serum fasting insulin concentration with cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.MethodsA total of 349 women, 249 women with polycystic ovary syndrome and 100 age-matched healthy controls, were recruited in...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 8, 2019 Category: Endocrinology Source Type: research

Proinsulin/insulin ratio as a predictor of insulin resistance in patients with diabetic nephropathy
ConclusionThis study demonstrate a strong relationship between insulin resistance and CKD and this relationship was stronger in the presence of obesity. Pro insulin/insulin ratio was found to be a significant predictor for insulin resistance. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 4, 2019 Category: Endocrinology Source Type: research

Vitamin D status of Turkish type 1 diabetic patients
ConclusionAs a result there were no difference between type 1 diabetics and healthy controls according to their vitamin D levels. Further studies with a larger sample of patients will improve our understanding of the relation of vitamin D and diabetes. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 30, 2019 Category: Endocrinology Source Type: research

Does reviewing fasting plasma glucose results patterns before glycosylated hemoglobin testing in type-2 diabetic patients lead to better testing decision?
ConclusionsSome FPG patterns were more predictive of HbA1c findings than focusing on one-time FPG results. Reviewing and recognizing certain patterns of FPGs prior to taking HbA1c tests can lead to better HbA1c testing decision than randomly prescribing the tests. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 29, 2019 Category: Endocrinology Source Type: research

Self-care behaviors in patients with type 2 diabetes: Education intervention base on social cognitive theory
This study aimed to determine the effect of education intervention, based on social cognitive theory, on self-care behaviors in patients with type 2 diabetes.MethodsThis study was conducted in descriptive and interventional stages. The effective factors and constructs of social cognitive theory were identified in a descriptive study (n = 320). After that, a quasi-experimental study was conducted to determine the effect of intervention on 120 diabetic patients whom were randomly assigned to experimental and control groups. The educational intervention was implemented in six 40 -minute sessions for the experimental group...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 28, 2019 Category: Endocrinology Source Type: research

A complete review of empagliflozin: Most specific and potent SGLT2 inhibitor used for the treatment of type 2 diabetes mellitus
Publication date: Available online 26 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Gita Chawla, Krishna Kr Chaudhary (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Affordability effect of diabetic medicine on Patient's treatment adherence case study: Itojo Hospital in Ntungamo District
The objective of this study was to assess the affordability effect of diabetic medicine on patient's treatment adherence among patients aged 18 and above who sought treatment at IH diabetic clinic.The source of data was primary which was collected by the researcher from IH. The independent variable was considered as affordability of the diabetic medicine and adherence was the dependent variable in this study. Findings showed that Sex, marital status, education level, estimated monthly income were significantly associated with treatment adherence at the bivariate level.The objectives of the study were looking at the afforda...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Level of hyperlipidemia in blood donors: A correlative study in North Indian population
Publication date: Available online 26 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Nishat Fatima, Tulika Chandra, Abbas Ali Mahdi, Devisha AgarwalAbstractBackgroundHyperlipidemia can be caused by abnormal elevation of lipids and lipoproteins in the blood. This increased can lead to heart disease. Risks which can be controlled include alcohol intake, physical activity, smoking, high blood pressure and genetic factors. Markers of increased cardiovascular risk appear to be lower in regular blood donor compared with single time donors as reflected by significantly lower total c...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Xanthine oxidase activity in type 2 diabetic Nigerians
ConclusionIncreased activity of xanthine oxidase in DM was associated with increased lipid peroxidation and could be a salient entity towards the onset on complications. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Effect of Sudarshan Kriya Yoga on anxiety, depression, and quality of life in people with type 2 diabetes: A pilot study in Kuwait
ConclusionResults indicate that SKY can be potentially beneficial for treating anxiety, insomnia, and depression associated in people with T2DM and in improving the quality of life in people with T2DM. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Proinsulin/insulin ratio as a predictor of insulin resistance and B-cell dysfunction in obese Egyptians ((insulin resistance & B-cell dysfunction in obese Egyptian))
Conclusionboth beta cell dysfunction and insulin resistance increased in obese group and so increased risk of type 2 diabetes. We found that Pro insulin/insulin ratio is a significant predictor for insulin resistance and Proinsulin is good predictor for beta cell dysfunction. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

C1q/TNF-related protein-3 and glucose homeostasis
Publication date: Available online 25 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Habib Yaribeygi, Farin Rashidfarrokhi, Stephen L. Atkin, Amirhossein SahebkarAbstractAdipokines are cytokines produced by adipocytes that may mediate inflammatory processes, whilst adipocyte-derived proteins may have the converse effect. C1q/TNF-related protein-3 or CTRP3 is a novel adipokine that is expressed and released by most types of human tissues including adipose tissue. This adipokine, considered as an adiponectin, can normalize blood glucose by several mechanisms. In addition, it ca...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Efficacy and safety of the second generation basal insulin analogs in type 2 diabetes mellitus: A critical appraisal
Publication date: Available online 25 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Hernando Vargas-Uricoechea, Juan Pablo Frias (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 27, 2019 Category: Endocrinology Source Type: research

Clinical characteristics, types and complications of diabetics with young age at the onset (14–25 years)
Conclusion: Osmotic symptoms and ketosis were more common in young age type 1 DM. Family history of DM was more common in parents of type 2 DM. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 25, 2019 Category: Endocrinology Source Type: research

Serum adiponectin and resistin: Correlation with metabolic syndrome and its associated criteria among temiar subtribe in Malaysia
This study aimed to investigate the relationship between serum adiponectin and resistin with MetS criteria among Temiar subtribe in Kuala Betis.Materials and methodsThis cross sectional study involved 123 subjects from Temiar subtribe in Kuala Betis, Gua Musang, Kelantan. MetS criteria were measured according to standard protocol by modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guideline. Anthropometric and biochemical measurements were performed including serum adiponectin and resistin for every study subjects.ResultsSerum adiponectin was significantly lower in MetS subjects (7.9...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 25, 2019 Category: Endocrinology Source Type: research

Association of glycemic status and interferon-γ production with leukocytes and platelet indices alterations in type2 diabetes
ConclusionDiabetes was correlated significantly with dyslipidemia and atherogenic risk in parallel with an increase in IFN-γ production and hematological inflammatory biomarkers; leukocytes, neutrophil/lymphocyte and platelet/lymphocyte ratios, MPV and PDW values. The amelioration in inflammatory biomarkers was associated with improvement in glycemic control. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 25, 2019 Category: Endocrinology Source Type: research

Are SGLT2 inhibitors joining the mainstream therapy for diabetes type 2?
ConclusionSGLT2 inhibitors have relatively safe profiles and can efficiently decrease HbA1c as well as fasting and postprandial glucose levels. Furthermore, SGLT2 inhibitors administrations are not associated with significant hypoglycemic episodes or weight gain. Thus, combination of SGLT2 inhibitors and other less harmful anti-diabetic medicines could be considered if there is no any contraindication. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 25, 2019 Category: Endocrinology Source Type: research

Factors associated with therapeutic target achievement in the control of complications in consequence of diabetes: A hospital-based study in west of Iran
ConclusionsThis study found that a considerable proportion of subjects with diabetes mellitus, insulin-dependent and diabetes mellitus, type II did not achieve the goals of care guidelines of Iran on secondary prevention of complications related to diabetes, especially vascular complication. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Should metformin still be the first-line of treatment in type 2 diabetes mellitus? A comprehensive review and suggested algorithm
Publication date: Available online 23 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Azza Khalifa Bin Hussain, Elamin Abdelgadir, Fauzia Rashid, Abeer Al Haj, Puja Thadani, Alaaeldin M.K. BashierAbstractFor more than a century, the high occurrences of coronary and peripheral artery diseases in diabetes mellitus patients has been well recognised; despite that, the ability to improve CV event rates by optimizing glycaemic control has remained elusive. Nevertheless, the last decade has seen several cardiovascular outcome clinical trials (CVOTs) of many antihyperglycemic agents t...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Imbalance between Angiotensin II - Angiotensin (1-7) system is associated with vascular endothelial dysfunction and inflammation in type 2 diabetes with newly diagnosed hypertension
ConclusionImbalance between AngiotensinII – Angiotensin1-7 is associated with increased inflammation and vascular dysfunction in diabetics and can contribute to development of hypertension in these patients. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Nutrition transition – Pattern IV: Leads Bangladeshi youth to the increasing prevalence of overweight and obesity
This study provides evidence of increasing trend and threat to overweight and obesity for the Bangladeshi youth. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Association between waist circumference and waist-to-height ratio with insulin resistance biomarkers in normal-weight adults working in a private educational institution
ConclusionElevated WC and high WHtR were associated with a high TG/HDL-C ratio in women. It is necessary to perform prospective follow-up studies in Peruvian population in order to corroborate our results. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

The effect of melatonin supplementation on lipid profile and anthropometric indices: A systematic review and meta-analysis of clinical trials
ConclusionsThe results of our systematic review and Meta-analyzes showed that supplementation of melatonin could be effective in improving lipid parameters and should be considered in the prevention of cardiovascular disease, although the effect of this supplement on anthropometric indices needs further investigation. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Are SGLT2 inhibitors joining the mainstream therapy for diabetes type 2?
ConclusionSGLT2 inhibitors have relatively safe profiles and can efficiently decrease HbA1c as well as fasting and postprandial glucose levels. Furthermore, SGLT2 inhibitors administrations are not associated with significant hypoglycemic episodes or weight gain. Thus, combination of SGLT2 inhibitors and other less harmful anti-diabetic medicines could be considered if there is no any contraindication. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Evaluation of antioxidant defense markers in relation to hormonal and insulin parameters in women with polycystic ovary syndrome (PCOS): A case-control study
ConclusionLow levels of antioxidants and increased oxidative stress with insulin resistance along with the observed correlation between these parameters suggest that women with PCOS are under oxidative stress which supports the concept that oxidative stress is involved in PCOS pathophysiology. Thus oxidative stress could be a contributory factor to future cardiovascular disease risk in these women in addition to known features like dyslipidemia, central obesity, etc. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Vitamin D status in diabetic patients (type 2) and its relation to glycemic control & diabetic nephropathy
ConclusionVitamin D level appeared to be lower in diabetic patients and is associated with poor glycemic control & microalbuminuria. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Determinant of postprandial triglyceride levels in healthy young adults
This study aims to assess the determinant of postprandial TG in healthy young adults.MethodsThis is a quasy-experimental study that involved 200 healthy young adults. This study compared fasting with postprandial TG and analyzed the relationship between postprandial TG with various demographic and metabolic parameters after ingestion of standardized high fat liquid meal.ResultThere was an upward trend from fasting TG to 2 h postprandial TG and 4 h postprandial TG. There was strong correlation between fasting TG and 2 h postprandial TG with 4 h postprandial TG (r = 0.731; p 
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 24, 2019 Category: Endocrinology Source Type: research

Visceral fat thickness of erosive and non-erosive reflux disease subjects in Indonesia's tertiary referral hospital
ConclusionVisceral fat thickness as measured by ultrasonography has no significant difference between NERD and ERD. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 21, 2019 Category: Endocrinology Source Type: research

Serum vitamin D status in type 2 diabetic patients from Gaza Strip
Publication date: Available online 17 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Maged M. Yassin, Abed El-Raoof D. Masoud, Mohammed M. YasinAbstractObjectiveTo assess serum vitamin D status and its relations to other biochemical parameters in type 2 diabetic patients from Gaza Strip.Materials and methodsThis case-control study included 58 type 2 diabetic patients as well as 58 non-diabetic controls. Patients and controls were matched for age and gender. Data were obtained from questionnaire interview, and biochemical analysis of blood samples.ResultsSerum vitamin D was si...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research

The effects of glycemic control on salivary lipid peroxidation in type II diabetic patients
Conclusionevaluation of salivary MDA levels could be useful in prediction of glycemic control. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research

A study to identify bacteriological profile and other risk factors among diabetic and non-diabetic foot ulcer patients in a guyanese hospital setting
Publication date: Available online 17 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Rajini Kurup, Abdullah Adil AnsariAbstractDiabetic foot infection is a global epidemic and a major public health concern. Development of microbial resistance to many antimicrobial agents in foot ulcer leads to serious complications. Therefore, the study aims to identify the microbiological profile and the potential risk factors among diabetic and non-diabetic foot ulcer patients.A prospective cross sectional study was carried out among 183 ulcer patients from diabetic foot clinic and wound dr...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research

Intensive monitoring for post-transplant diabetes mellitus and treatment with dipeptidyl peptidase-4 inhibitor therapy
Publication date: Available online 17 April 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Srivathsan Thiruvengadam, Brian Hutchison, Wai Lim, Kirsten Bennett, Gloria Daniels, Narelle Cusack, Angela Jacques, Brett Cawley, Shreyas Thiruvengadam, Aron ChakeraAbstractAimCurrent monitoring practices fail to diagnose patients with post-transplant hyperglycaemia and tend to delay initiation of treatment, which potentially results in adverse graft and morbidity outcomes. This real-world study set out to assess the impact on insulin resistance indices of a new clinical pathway for diagnosi...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research

Effect of Patient Education on Metabolic Syndrome Components among Females in Zagazig University Outpatient Clinics, Egypt: An Intervention Study.
ConclusionPatient education improved all MS components and considered significantly more effective than traditionally adopted management. So, we recommend its application on all MS patients. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research

Study of Angiopoietin-2 and vascular endothelial growth factor as markers of diabetic nephropathy onset in egyptians diabetic patients with non-albuminuric state
ConclusionVEGF and Ang-2 were significantly elevated in diabetic nephropathy patients without albuminuria, their levels steadily increase with the progress of albuminuria, So can use them as markers for diagnosis of diabetic nephropathy onset and progression specially in patients without an increase in albumin excretion . (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research

Frequency of type I and II diabetes in newly diagnosed diabetic patients: Measuring C-Peptide level
ConclusionAnti-GAD test can be used as a predictive test for early diagnosis of disease and screening of people with a diagnosis of diabetes based on the type of diabetes. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 18, 2019 Category: Endocrinology Source Type: research