Gender Differences in Depression in the General Population of Indonesia: Confounding Effects
CONCLUSIONS: Possible confounding effects on the association between gender and depression are methodological issues, cultural orientation transition, and stereotypical symptoms. Low depression scores found for gender may reflect dimension-counterpart coping strategies.PMID:34258060 | PMC:PMC8253638 | DOI:10.1155/2021/3162445 (Source: Depression Research and Treatment)
Source: Depression Research and Treatment - July 14, 2021 Category: Psychiatry Authors: Andi Agus Mumang Saidah Syamsuddin Ida Leida Maria Irawan Yusuf Source Type: research

Prevalence and Associated Factors of Depressive Disorder among Prisoners in Mekelle General Prison Center, Tigray, Ethiopia: A Cross-Sectional Study Design
Depress Res Treat. 2021 Jun 1;2021:1942674. doi: 10.1155/2021/1942674. eCollection 2021.ABSTRACTBACKGROUND: Depression is the most prevalent mental disorder among prisoners and is the second leading cause of disability worldwide. Depression affects more for those who are less educated, female, single, and young prisoners, and worldwide prevalence of depression among prisoners is 10.2% and 14% for male and female prisoners, respectively. However, a study conducted on prevalence of depression and associated factors is scarce in Ethiopia (Tigray) despite there is high magnitude. Methodology. An institution-based cross-section...
Source: Depression Research and Treatment - June 23, 2021 Category: Psychiatry Authors: Solomon Gidey Welu Desta Hailu Aregawi Hagos Tsegabrhan Gebreslassie Kokob Gebru Kidanu Source Type: research

Adenylyl Cyclase (AC) Mediates the Antidepressant-Like Effects of Tropisetron on a Mouse Model of Maternal Separation Stress
Depress Res Treat. 2021 Apr 22;2021:5586119. doi: 10.1155/2021/5586119. eCollection 2021.ABSTRACTThe adenylyl cyclase (AC) pathway is involved in the pathophysiology of depression. Finding new antidepressants with high medicinal properties and low side effects is warranted. Therefore, this study was designed to determine the antidepressant-like effect of tropisetron on a maternal separation (MS) model in mice, considering the possible role of AC. NMRI male mice were divided into eleven groups. The control group was treated with saline and MS groups were treated with saline, tropisetron (a 5-HT3 receptor antagonist) at dose...
Source: Depression Research and Treatment - May 12, 2021 Category: Psychiatry Authors: Ali Hosseinzadeh Shakiba Nasiri Boroujeni Elham Saghaei Zahra Loriooini Saeid Habibian Dehkordi Shima Balali-Dehkordi Mohammad Rahimi-Madiseh Hossein Amini-Khoei Source Type: research