Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
ConclusionU.S. military veterans who are APOE ε4 allele carriers and exposed to a high number of traumas may be at increased risk for developing PTSD symptoms than ε4 noncarriers. Greater social support may moderate this association, thereby highlighting the potential importance of social support promoting interventions in mitigating the effect of ε4 × cumulative trauma burden on PTSD risk. (Source: Depression and Anxiety)
Source: Depression and Anxiety - November 24, 2017 Category: Psychiatry Authors: Natalie P. Mota, Shizhong Han, Ilan Harpaz ‐Rotem, Paul Maruff, John H. Krystal, Steven M. Southwick, Joel Gelernter, Robert H. Pietrzak Tags: RESEARCH ARTICLE Source Type: research

The impact of resilience and subsequent stressful life events on MDD and GAD
ConclusionsThe pattern of findings was the same for MDD and GAD, wherein main effects and two‐way interactions of resilience and SLEs were significant, such that greater resilience was protective even in the context of high numbers of past‐year SLEs. The three‐way interaction was not significant, suggesting that the relationship between SLEs and resilience on psychopathology was the same for both men and women. Findings support the conceptualization of resilience as a buffer against the impact of future life stressors on common internalizing psychopathology. Longitudinal designs and trajectory‐based studies that in...
Source: Depression and Anxiety - November 24, 2017 Category: Psychiatry Authors: Christina M. Sheerin, Mackenzie J. Lind, Emily A. Brown, Charles O. Gardner, Kenneth S. Kendler, Ananda B. Amstadter Tags: RESEARCH ARTICLE Source Type: research

Adverse life events increase risk for postpartum psychiatric episodes: A population ‐based epidemiologic study
ConclusionsACE primarily due to parental psychopathology and disability contributes to increased risk of postpartum psychiatric episodes; and greater numbers of ACE increases risk for postpartum psychiatric illness with an observed dose–response effect. Future work should explore genetic and environmental factors that increase risk and/or confer resilience. (Source: Depression and Anxiety)
Source: Depression and Anxiety - November 24, 2017 Category: Psychiatry Authors: S. Meltzer ‐Brody, J. T. Larsen, L. Petersen, J. Guintivano, A. Di Florio, W. C. Miller, P. F. Sullivan, T. Munk‐Olsen Tags: RESEARCH ARTICLE Source Type: research

President's letter November 2017
(Source: Depression and Anxiety)
Source: Depression and Anxiety - November 7, 2017 Category: Psychiatry Authors: Karen Lynn Cassiday Tags: ADAA PRESIDENT'S LETTER Source Type: research

Issue Information
(Source: Depression and Anxiety)
Source: Depression and Anxiety - November 7, 2017 Category: Psychiatry Tags: ISSUE INFORMATION Source Type: research

The impact of race and ethnicity on rates of return to psychotherapy for depression
ConclusionsProvider and healthcare system variation were stronger predictors of patient return to psychotherapy than race and ethnicity. More research is needed to understand why providers and healthcare systems determine psychotherapy return rates for patients of all racial and ethnic groups. (Source: Depression and Anxiety)
Source: Depression and Anxiety - November 2, 2017 Category: Psychiatry Authors: John E. Zeber, Karen J. Coleman, Heidi Fischer, Tae K. Yoon, Brian K. Ahmedani, Arne Beck, Samuel Hubley, Zac E. Imel, Rebecca C. Rossom, Susan M. Shortreed, Christine Stewart, Beth E. Waitzfelder, Greg E. Simon Tags: RESEARCH ARTICLE Source Type: research

Erratum: Quantitative evaluation of the clinical efficacy of attention bias modification treatment for anxiety disorders
(Source: Depression and Anxiety)
Source: Depression and Anxiety - November 1, 2017 Category: Psychiatry Authors: Marian Linetzky, Lee Pergamin ‐Hight, Daniel S. Pine, Yair Bar‐Haim Tags: ERRATUM Source Type: research

Depressive symptoms prior to and after incident cardiovascular disease and long ‐term survival. A population‐based study of older persons
ConclusionsDuring 15 years follow‐up in community‐dwelling older adults, the relation between higher depressive symptoms measured before first incident CVD and mortality was not independent of health status. Whereas, higher depressive symptoms measured after CVD was associated with increased mortality, was not independent of pre‐CVD depressive symptoms. Given the associations observed between positive affect and mortality, positive affect may be the reason we observed a relation between depressive symptoms and mortality. (Source: Depression and Anxiety)
Source: Depression and Anxiety - November 1, 2017 Category: Psychiatry Authors: Rosanne Freak ‐Poli, M. Arfan Ikram, Oscar H Franco, Albert Hofman, Henning Tiemeier Tags: RESEARCH ARTICLE Source Type: research

Vortioxetine versus placebo in major depressive disorder comorbid with social anxiety disorder
ConclusionsIn this preliminary trial vortioxetine appears safe and effective for patients with MDD comorbid with SAD, with robust effect sizes on dimensional measures of both depression and social anxiety, but failure to separate from placebo on the primary outcome measure of composite responder rate. More studies of patients with comorbid conditions are needed, as this mirrors what is often seen in clinical practice. (Source: Depression and Anxiety)
Source: Depression and Anxiety - November 1, 2017 Category: Psychiatry Authors: Michael R. Liebowitz, Jason Careri, Kyra Blatt, Ann Draine, Junko Morita, Melissa Moran, Rita Hanover Tags: RESEARCH ARTICLE Source Type: research

Hypothalamic –pituitary–thyroid (HPT) axis functioning in anxiety disorders. A systematic review
Abstract Depression has repeatedly been linked to subclinical hypothyroidism, and thyroid hormones have successfully been used to augment antidepressant treatment. By contrast, the extent of thyroid dysfunction in anxiety disorders remains less clear. This is surprising, given that anxiety‐related symptoms (e.g., nervousness, palpitations, increased perspiration) are highly prevalent in hyperthyroidism. The present study was undertaken to synthesize the literature on hypothalamic–pituitary–thyroid (HPT) axis functioning in anxiety disorders. The PubMed and PsycINFO databases were systematically searched. Three types ...
Source: Depression and Anxiety - October 24, 2017 Category: Psychiatry Authors: Susanne Fischer, Ulrike Ehlert Tags: REVIEW Source Type: research

President's Letter October 2017
(Source: Depression and Anxiety)
Source: Depression and Anxiety - October 5, 2017 Category: Psychiatry Authors: Karen Lynn Cassiday Tags: ADAA PRESIDENT'S LETTER Source Type: research

Issue Information
(Source: Depression and Anxiety)
Source: Depression and Anxiety - October 5, 2017 Category: Psychiatry Tags: ISSUE INFORMATION Source Type: research

Predictive validity and correlates of self ‐assessed resilience among U.S. Army soldiers
ConclusionsFindings supported validity of self‐assessed resilience among soldiers, although its predictive effect on incidence of emotional disorder was modest. In conjunction with assessment of known risk factors, measurement of resilience could help predict adaptation to foreseen stressors like deployment. (Source: Depression and Anxiety)
Source: Depression and Anxiety - October 1, 2017 Category: Psychiatry Authors: Laura Campbell ‐Sills, Ronald C. Kessler, Robert J. Ursano, Xiaoying Sun, Charles T. Taylor, Steven G. Heeringa, Matthew K. Nock, Nancy A. Sampson, Sonia Jain, Murray B. Stein Tags: RESEARCH ARTICLE Source Type: research

Erratum
(Source: Depression and Anxiety)
Source: Depression and Anxiety - October 1, 2017 Category: Psychiatry Tags: ERRATUM Source Type: research

A randomized controlled pilot trial of vilazodone for adult separation anxiety disorder
ConclusionsFindings demonstrate feasibility of a clinical trial in ASAD, and they suggest that vilazodone may have efficacy in the treatment of ASAD and warrants further study. (Source: Depression and Anxiety)
Source: Depression and Anxiety - October 1, 2017 Category: Psychiatry Authors: Franklin R. Schneier, Danielle M. Moskow, Tse ‐Hwei Choo, Hanga Galfalvy, Raphael Campeas, Arturo Sanchez‐Lacay Tags: RESEARCH ARTICLE Source Type: research