Effect of matrix metalloproteinase 8 inhibitor and chlorhexidine on the cytotoxicity, oxidative stress and cytokine level of MDPC-23
The deterioration of resin –dentin bonds has become a focus of research in contemporary adhesive dentistry due to the proteolysis of collagen matrix of the hybrid layers [1]. Chlorhexidine (CHX), a nonspecific protease inhibitor of matrix metalloproteinase (MMP) and cysteine cathepsins, has been found to be beneficial to ma intaining the integrity of the hybrid layer and preventing the loss of bond strength with time [2,3]. However, emerging evidence suggests that CHX exhibits both cytotoxicity and genotoxicity to oral cells, which greatly restricts its application in adhesive dentistry [4–6]. (Source: Dental Materials)
Source: Dental Materials - September 17, 2018 Category: Materials Science Authors: Qianmin Ou, Lingping Tan, Xiaojun Huang, Qipei Luo, Yan Wang, Xuefeng Lin Source Type: research

Multifaceted roles of environmental factors toward dental implant performance: Observations from clinical retrievals and in vitro testing
Commercially pure (cp) titanium (Ti) is currently the material of choice for dental implant applications due to its biocompatibility, mechanical properties, and excellent corrosion resistance [1,2]. Titanium oxidation constitutes the principal reason of its excellent biocompatibility. Earlier in vitro studies have suggested that Ti oxide (TiO2) can pacify tissue-destroying agents immediately after surgical trauma inherent to implantation by reducing free radical production [3,4]. The original theory of osseointegration rested on the passivation of implant titanium surface [5]. (Source: Dental Materials)
Source: Dental Materials - September 13, 2018 Category: Materials Science Authors: Sathyanarayanan Sridhar, Frederick Wang, Thomas G. Wilson, Pilar Valderrama, Kelli Palmer, Danieli C. Rodrigues Source Type: research

Biofilm formation on restorative materials and resin composite cements
Dental implants made from zirconia can be considered a promising metal free alternative to the well-established titanium implants [1 –4]. Due to the materials' sensitivity to tensile stress, most zirconia implants are offered as one-piece devices. Therefore, a restoration has to be cemented directly on the implant. For cemented restorations on titanium implants, biological complications as a consequence of remaining excess ceme nt were recorded [5–9]. Removing excess cement after fixing a prosthodontic restoration on an implant is challenging for dentists and if not performed adequately, excess cement acts as a co-fact...
Source: Dental Materials - September 13, 2018 Category: Materials Science Authors: Monika Astasov-Frauenhoffer, Stephanie Glauser, Jens Fischer, Fredy Schmidli, Tuomas Waltimo, Nadja Rohr Source Type: research

Effect of aging and testing method on bond strength of CAD/CAM fiber-reinforced composite to dentin
Over the years, clinicians have relied upon laboratory evaluations to choose which adhesive systems to use in their daily practice. Although the relationship between bond strength tests and clinical performance of dental adhesives remains questionable [1,2], recent evidence shows that clinical results can, to some extent, be estimated based upon laboratory results [3 –5]. Moreover, mechanical testing of bonded interfaces has provided some valuable information to identify substrate variables [6,7] and to define guidelines for application procedures [8]. (Source: Dental Materials)
Source: Dental Materials - September 13, 2018 Category: Materials Science Authors: Lucas Fracassi de Oliveira Lino, Camila Moreira Machado, Vitor Guar çoni de Paula, Hugo Alberto Vidotti, Paulo G. Coelho, Ernesto Byron Benalcázar Jalkh, Thiago Amadei Pegoraro, Estevam Augusto Bonfante Source Type: research

Effect of loading frequency on cyclic fatigue lifetime of a standard-diameter implant with an internal abutment connection
Over the past decade, root-form titanium dental implants have been widely used to restore missing teeth due to improvements in implant designs and understanding of their proper indications [1]. However, biological and technical complications of dental implants commonly occur, and this sometimes significantly compromises the clinical outcome of dental implant therapy and the quality of life for patients. Technical complications of dental implants include fracture or loosening of the abutment and abutment screw, implant body fracture, and superstructure fractures. (Source: Dental Materials)
Source: Dental Materials - September 13, 2018 Category: Materials Science Authors: Yuanyuan Duan, Jason A. Griggs Source Type: research

FTIR characterization of the setting reaction of biodentine ™
To provide insight of the setting reactions of Biodentine ™, a hydraulic calcium silicate cement, based upon observations using Fourier Transform Infra-Red (FTIR) spectroscopy. (Source: Dental Materials)
Source: Dental Materials - September 12, 2018 Category: Materials Science Authors: J. Alotaibi, S. Saji, M.V. Swain Source Type: research

Influence of light-cured luting agents and associated factors on the color of ceramic laminate veneers: A systematic review of in vitro studies
The luting agent plays a significant role in the appearance of ceramic laminate veneers (CLV), allowing improved/stable shade matching with adjacent teeth. A systematic review was conducted to investigate the influence of light-cured luting agents and color-associated factors aiming to draw guidelines for stable shade matching of CLV. The paper has also given an overview of the compositional characteristics of all luting agents and ceramic systems whose performance was presented herein. (Source: Dental Materials)
Source: Dental Materials - September 10, 2018 Category: Materials Science Authors: Ana Paula Perroni, Marina R. Kaizer, Alvaro Della Bona, Rafael R. Moraes, No éli Boscato Source Type: research

Functionalized epigallocatechin gallate copolymer inhibit dentin matrices degradation: Mechanical, solubilized telopeptide and proteomic assays
Organic dentin matrices, composed mainly of type I collagen and non-collagenous proteins, contain proteolytic enzymes such as matrix metalloproteinases (MMPs) and cysteine cathepsins, developmentally secreted as latent proenzymes. In adhesive procedures and during microbial metabolism of carbohydrates, when there is a drop of pH in the dentinal microenvironment, these proteases are uncovered and activated, and are regarded as contributors to dentin degradation. (Source: Dental Materials)
Source: Dental Materials - September 7, 2018 Category: Materials Science Authors: Anuradha Prakki, Yaoyang Xiong, Jana ína Bortolatto, Lucélia Lemes Gonçalves, Arwa Bafail, Greg Anderson, Alexander Terry Stavroullakis Source Type: research

Acrylamides and methacrylamides as alternative monomers for dental adhesives
The degradation of adhesive resin is related to the formulation of dental adhesives with hydrophilic functional monomers and the presence of water. These adhesive systems are composed by monomers having hydroxyl, carboxyl, and ester groups making them more prone to water sorption, leading to the disruption of covalent bonds between monomers of polymeric chain and, consequently, resin weight loss [1 –5]. Therefore, resulting in permeable adhesive interface that also promotes lower elastic modulus of adhesive resin and compromises the long-term of restoration treatment [6]. (Source: Dental Materials)
Source: Dental Materials - September 7, 2018 Category: Materials Science Authors: St éfani Becker Rodrigues, Cesar Liberato Petzhold, Douglas Gamba, Vicente Castelo Branco Leitune, Fabrício Mezzomo Collares Source Type: research

Modulating pH through lysine integrated dental adhesives
Over 170 million composite and amalgam restorations are placed annually in the United States and results from clinical studies suggest that more than half are replacements for failed restorations [1]. The primary reason for restoration failure is recurrent decay, i.e. decay on the margins of existing restorations, but the incidence of recurrent decay can be 3 to 3.5 times greater for composite restorations [2,3]. A clear difference between amalgam and composite is the inherent ability of amalgam to seal marginal defects, i.e. (Source: Dental Materials)
Source: Dental Materials - September 7, 2018 Category: Materials Science Authors: Linyong Song, Xueping Ge, Qiang Ye, Kyle Boone, Sheng-Xue Xie, Anil Misra, Candan Tamerler, Paulette Spencer Source Type: research

Functions of transcription factors NF- κB and Nrf2 in the inhibition of LPS-stimulated cytokine release by the resin monomer HEMA
Theoretical model of the HEMA-induced inhibition of LPS-stimulated cytokine secretion. (Source: Dental Materials)
Source: Dental Materials - September 6, 2018 Category: Materials Science Authors: Helmut Schweikl, Marialucia Gallorini, Gerd P öschl, Vera Urmann, Christine Petzel, Carola Bolay, Karl-Anton Hiller, Amelia Cataldi, Wolfgang Buchalla Source Type: research

Stability and aging resistance of a zirconia oral implant using a carbon fiber-reinforced screw for implant-abutment connection
Since their first application more than 50years ago [1], titanium implants constantly developed over time. Improvements affected the implant surface (turned, micro-roughened, active), the implant-abutment connection (from external to internal connections and from matched to switched platforms), and the alloys used for fabrication (from gold to titanium for abutment-screws and from pure titanium to titanium –zirconium alloys for the bulk material) [2], significantly reducing the incidence of technical and biological complications over time [3]. (Source: Dental Materials)
Source: Dental Materials - September 1, 2018 Category: Materials Science Authors: Benedikt C. Spies, Alexander Fross, Erik Adolfsson, Aimen Bagegni, Sam Doerken, Ralf-Joachim Kohal Source Type: research

Evaluating dental zirconia
To survey simple contact testing protocols for evaluating the mechanical integrity of zirconia dental ceramics. Specifically, to map vital material property variations and to quantify competing damage modes. (Source: Dental Materials)
Source: Dental Materials - August 29, 2018 Category: Materials Science Authors: Yu Zhang, Brian R. Lawn Source Type: research

Calcium phosphates as ion-releasing fillers in restorative resin-based materials
Calcium phosphates (CaP) are the main constituents of the mineral phase in bones and teeth and, along with calcium silicates and bioactive glasses, have been extensively investigated in remineralization of enamel and dentin. When used as ion-releasing fillers in resin-based materials, they could contribute to extend the service life of adhesive restorations, remineralize caries-affected dentin or prevent caries lesions under sealants and orthodontic brackets. However, the development of resin-based bioactive materials is not straightforward because of the several compositional variables involved in ion release. (Source: Dental Materials)
Source: Dental Materials - August 20, 2018 Category: Materials Science Authors: Roberto Ruggiero Braga Source Type: research

Editorial Board
(Source: Dental Materials)
Source: Dental Materials - August 15, 2018 Category: Materials Science Source Type: research