Diagnostic flow of patients in a national fast-track referral system for malignant melanoma
Dan Med J. 2024 Jan 25;71(2):A07230435. doi: 10.61409/A07230435.ABSTRACTElderly people and patients with chronic lifestyle diseases are at risk of being hit harder by environmental influences. Environmental impacts increase the risk of various lifestyle diseases. Biomimetics gives us a unique opportunity to find new treatments for lifestyle diseases and counteract health effects of environmental threats. A biomimetic alliance for better health achieved through cross-disciplinal collaboration may not only contribute to better health but also to a better and more sustainable environment: What is good for the planet is good f...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Silje Haukali Omland Anna Harager Peter Phillipsen Katrine Karmisholt Source Type: research

Adherence to guidelines prior to endoscopic sinus surgery in patients with chronic rhinosinusitis and asthma
CONCLUSIONS: Asthma was lower in the study population than in the literature. Danish national guidelines on CRS management are insufficient regarding attention to asthma. Results call attention to the need for more multidisciplinary team management.FUNDING: None.TRIAL REGISTRATION: Not relevant.PMID:38314735 | DOI:10.61409/A04230241 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Lotte Buskbjerg N øhr Therese Ovesen Kasra Zainali-Gill Source Type: research

Outpatient pain service in trauma and orthopaedic surgery
CONCLUSIONS: Establishing an outpatient pain service for persistent pain after surgery and trauma may encourage the use of analgesia regimens that are in accordance with international guidelines and ensure that opioids are not continued inappropriately.FUNDING: None.TRIAL REGISTRATION: Not relevant.PMID:38314736 | DOI:10.61409/A02230105 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Claus Bredahl Simone H østgaard Jannie Bisgaard Source Type: research

Infrequent transition to direct oral anticoagulants in patients with cancer
CONCLUSIONS. In patients with cancer, the one-year cumulative incidence of switching from LMWH to DOAC was less-t 35% in patients eligible for DOAC, revealing a potential for improved anticoagulant treatment. Furthermore, contemporary data elaborated on potential DDIs between DOACs/antineoplastic agents.FUNDING: "Helsefonden" (21-B-0350) and the "Karen Elise Jensens Fonden" (29-4-2021) funded the study.TRIAL REGISTRATION: Not relevant.PMID:38314737 | DOI:10.61409/A05230278 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Nina Nouhravesh Caroline Sindet-Pedersen Maja Hellfritzsch Ali Akil Al-Alak Thomas K ümler Erik L Grove Morten Lamberts Source Type: research

"Pain without loosening"-revisions of knee arthroplasties in the Danish Knee Arthroplasty Register
CONCLUSIONS: The indication "pain without loosening" covered patients revised due to pain, but other hidden indications were also present. Stiffness and malposition of components were hidden indications and these are not provided as indication options in the DKR and other registers. The relatively high frequency of arthrosis grade 1-2 prior to primary knee arthroplasty is concerning and may explain the occurrence of knee pain without any other pathology present.FUNDING: The Danish Rheumatism Association, the Region of Southern Denmark, the Research Fund of Region Zeeland and Region of Southern Denmark, and the University o...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Kristine Bollerup Arndt Henrik Morville Schr øder Anders Troelsen Mikkel Rathsach Andersen Lasse Enkeb ølle Rasmussen Martin Lindberg-Larsen Source Type: research

Reduced graft survival in renal transplant patients with urinary tract infections - a meta-analysis
CONCLUSIONS: Filtering the literature for a strict definition of UTI allowed us to establish an association between UTI and graft loss in renal transplant patients. However, further investigation and stronger studies using the Goldman criteria are needed to allow stratification for UTI severity and effect on graft loss.PMID:38314732 | DOI:10.61409/A06230424 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Aimi Dm Hamilton Helle A Pr ætorius Source Type: research

The therapeutic potential of galanin in the management of pain - a review article
Dan Med J. 2024 Jan 23;71(2):A10230653. doi: 10.61409/A10230653.ABSTRACTNeuropeptides represent the most diverse family of neurotransmitters counting numerous members and even more G protein-coupled receptors, all of which are potential targets for drug development. Here, we focus on galanin and its three receptors by describing their possible involvement in pain and regeneration. Although animal experiments indicate that galanin, together with other molecules, may act as an endogenous system protecting against pain and improving nerve growth, these results have so far not been translated into patient treatments.PMID:38314...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Tomas H ökfelt Zsuzsanna Wiesenfeld-Hallin Source Type: research

Diagnostic flow of patients in a national fast-track referral system for malignant melanoma
Dan Med J. 2024 Jan 25;71(2):A07230435. doi: 10.61409/A07230435.ABSTRACTElderly people and patients with chronic lifestyle diseases are at risk of being hit harder by environmental influences. Environmental impacts increase the risk of various lifestyle diseases. Biomimetics gives us a unique opportunity to find new treatments for lifestyle diseases and counteract health effects of environmental threats. A biomimetic alliance for better health achieved through cross-disciplinal collaboration may not only contribute to better health but also to a better and more sustainable environment: What is good for the planet is good f...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Silje Haukali Omland Anna Harager Peter Phillipsen Katrine Karmisholt Source Type: research

Adherence to guidelines prior to endoscopic sinus surgery in patients with chronic rhinosinusitis and asthma
CONCLUSIONS: Asthma was lower in the study population than in the literature. Danish national guidelines on CRS management are insufficient regarding attention to asthma. Results call attention to the need for more multidisciplinary team management.FUNDING: None.TRIAL REGISTRATION: Not relevant.PMID:38314735 | DOI:10.61409/A04230241 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Lotte Buskbjerg N øhr Therese Ovesen Kasra Zainali-Gill Source Type: research

Outpatient pain service in trauma and orthopaedic surgery
CONCLUSIONS: Establishing an outpatient pain service for persistent pain after surgery and trauma may encourage the use of analgesia regimens that are in accordance with international guidelines and ensure that opioids are not continued inappropriately.FUNDING: None.TRIAL REGISTRATION: Not relevant.PMID:38314736 | DOI:10.61409/A02230105 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Claus Bredahl Simone H østgaard Jannie Bisgaard Source Type: research

Infrequent transition to direct oral anticoagulants in patients with cancer
CONCLUSIONS. In patients with cancer, the one-year cumulative incidence of switching from LMWH to DOAC was less-t 35% in patients eligible for DOAC, revealing a potential for improved anticoagulant treatment. Furthermore, contemporary data elaborated on potential DDIs between DOACs/antineoplastic agents.FUNDING: "Helsefonden" (21-B-0350) and the "Karen Elise Jensens Fonden" (29-4-2021) funded the study.TRIAL REGISTRATION: Not relevant.PMID:38314737 | DOI:10.61409/A05230278 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Nina Nouhravesh Caroline Sindet-Pedersen Maja Hellfritzsch Ali Akil Al-Alak Thomas K ümler Erik L Grove Morten Lamberts Source Type: research

"Pain without loosening"-revisions of knee arthroplasties in the Danish Knee Arthroplasty Register
CONCLUSIONS: The indication "pain without loosening" covered patients revised due to pain, but other hidden indications were also present. Stiffness and malposition of components were hidden indications and these are not provided as indication options in the DKR and other registers. The relatively high frequency of arthrosis grade 1-2 prior to primary knee arthroplasty is concerning and may explain the occurrence of knee pain without any other pathology present.FUNDING: The Danish Rheumatism Association, the Region of Southern Denmark, the Research Fund of Region Zeeland and Region of Southern Denmark, and the University o...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Kristine Bollerup Arndt Henrik Morville Schr øder Anders Troelsen Mikkel Rathsach Andersen Lasse Enkeb ølle Rasmussen Martin Lindberg-Larsen Source Type: research

Reduced graft survival in renal transplant patients with urinary tract infections - a meta-analysis
CONCLUSIONS: Filtering the literature for a strict definition of UTI allowed us to establish an association between UTI and graft loss in renal transplant patients. However, further investigation and stronger studies using the Goldman criteria are needed to allow stratification for UTI severity and effect on graft loss.PMID:38314732 | DOI:10.61409/A06230424 (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Aimi Dm Hamilton Helle A Pr ætorius Source Type: research

The therapeutic potential of galanin in the management of pain - a review article
Dan Med J. 2024 Jan 23;71(2):A10230653. doi: 10.61409/A10230653.ABSTRACTNeuropeptides represent the most diverse family of neurotransmitters counting numerous members and even more G protein-coupled receptors, all of which are potential targets for drug development. Here, we focus on galanin and its three receptors by describing their possible involvement in pain and regeneration. Although animal experiments indicate that galanin, together with other molecules, may act as an endogenous system protecting against pain and improving nerve growth, these results have so far not been translated into patient treatments.PMID:38314...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Tomas H ökfelt Zsuzsanna Wiesenfeld-Hallin Source Type: research

Diagnostic flow of patients in a national fast-track referral system for malignant melanoma
Dan Med J. 2024 Jan 25;71(2):A07230435. doi: 10.61409/A07230435.ABSTRACTElderly people and patients with chronic lifestyle diseases are at risk of being hit harder by environmental influences. Environmental impacts increase the risk of various lifestyle diseases. Biomimetics gives us a unique opportunity to find new treatments for lifestyle diseases and counteract health effects of environmental threats. A biomimetic alliance for better health achieved through cross-disciplinal collaboration may not only contribute to better health but also to a better and more sustainable environment: What is good for the planet is good f...
Source: Danish Medical Journal - February 5, 2024 Category: General Medicine Authors: Silje Haukali Omland Anna Harager Peter Phillipsen Katrine Karmisholt Source Type: research