Investigation of IL-6 serum level in COVID-19 patients with positive COVID-19 IgG/IgM antibody titers to check inflammation and disease progression
CONCLUSION: As a result, the relationship between different serum levels of cytokine IL-6 with different titers of IgM and IgG antibodies was observed in both male and female populations. In general, it can be concluded that the correlation between different concentrations of IL-6 with different IgM titers was similar in both men and women, but in the case of different IgG titers, this correlation was higher in women than men.PMID:38432065 | DOI:10.1016/j.cyto.2024.156564 (Source: Cytokine)
Source: Cytokine - March 3, 2024 Category: Molecular Biology Authors: Samaneh Mollazadeh Mahmoud Mahmoudi Mojgan Mohammadi Ramiar Kamal Kheder Hussein Nasiri Mahallati Salime Sarbaz Haghighi Elnaz Masoumi Zahra Javanmardi Seyed-Alireza Esmaeili Source Type: research
Th2-predominant immune response underlies the pathogenesis of Dengue
CONCLUSION: The study reveals a Th2-predominant immune response in all Dengue patients, regardless of disease severity, with overexpression of IL-8 and MIP-1α being observed in patients with warning signs.PMID:38430693 | DOI:10.1016/j.cyto.2024.156562 (Source: Cytokine)
Source: Cytokine - March 2, 2024 Category: Molecular Biology Authors: Dipesh Kale Ashish Kumar Vyas Girish Chandra Bhatt Ashvini Kumar Yadav Anirudh K Singh Shashwati Nema Debasis Biswas Source Type: research
Cancer energy reprogramming and the immune responses
This study highlighted some prospects and future experiments in harnessing the host immune response towards the altered energy metabolism due to cancer.PMID:38430694 | DOI:10.1016/j.cyto.2024.156561 (Source: Cytokine)
Source: Cytokine - March 2, 2024 Category: Molecular Biology Authors: Yuan Xingxing Serge Yannick Ouedraogo Muhammed Tarawally Yurong Tan Ousman Bajinka Source Type: research
Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice
CONCLUSIONS: Our study suggests that PF-127/PH hydrogel has excellent potential for treating traumatic skin defects.PMID:38417214 | DOI:10.1016/j.cyto.2024.156556 (Source: Cytokine)
Source: Cytokine - February 28, 2024 Category: Molecular Biology Authors: Chenggang Huang Jiajia Teng Wei Liu Junzhe Wang An Liu Source Type: research
Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice
CONCLUSIONS: Our study suggests that PF-127/PH hydrogel has excellent potential for treating traumatic skin defects.PMID:38417214 | DOI:10.1016/j.cyto.2024.156556 (Source: Cytokine)
Source: Cytokine - February 28, 2024 Category: Molecular Biology Authors: Chenggang Huang Jiajia Teng Wei Liu Junzhe Wang An Liu Source Type: research
Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice
CONCLUSIONS: Our study suggests that PF-127/PH hydrogel has excellent potential for treating traumatic skin defects.PMID:38417214 | DOI:10.1016/j.cyto.2024.156556 (Source: Cytokine)
Source: Cytokine - February 28, 2024 Category: Molecular Biology Authors: Chenggang Huang Jiajia Teng Wei Liu Junzhe Wang An Liu Source Type: research
Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice
CONCLUSIONS: Our study suggests that PF-127/PH hydrogel has excellent potential for treating traumatic skin defects.PMID:38417214 | DOI:10.1016/j.cyto.2024.156556 (Source: Cytokine)
Source: Cytokine - February 28, 2024 Category: Molecular Biology Authors: Chenggang Huang Jiajia Teng Wei Liu Junzhe Wang An Liu Source Type: research
Hookworm infection as a model for deepen knowledge of iron metabolism and erythropoiesis in anemia
In this study we investigated the effects of hookworm infection on iron metabolism and how the hosts response to anemia is affected using hamsters infected with Ancylostoma ceylanicum as a model. Our data revealed interesting relationships between infection-induced anemia, erythropoiesis, iron metabolism, and immune modulation, such that the elevated production of erythropoietin (EPO) in renal tissue indicated intensified erythropoiesis in response to anemia. Additionally, the increased expression of the erythroferrone (ERFE) gene in the spleen suggested its involvement in iron regulation and erythropoiesis. Gene expressio...
Source: Cytokine - February 27, 2024 Category: Molecular Biology Authors: Luis Fernando Viana Furtado William Pereira Alves Vivian Jordania da Silva Élida Mara Leite Rabelo Source Type: research
Expression of Siglec-9 in peripheral blood neutrophils was increased and associated with disease severity in patients with AECOPD
CONCLUSION: The increased expression of Siglec-9 in peripheral blood neutrophils of AECOPD patients leads to elevated NET expression in induced sputum, exacerbating the systemic inflammatory response and worsening lung function and quality of life in these patients.PMID:38412768 | DOI:10.1016/j.cyto.2024.156558 (Source: Cytokine)
Source: Cytokine - February 27, 2024 Category: Molecular Biology Authors: Linyang Ge Nan Wang Zi Chen Shuanglan Xu Linfu Zhou Source Type: research
Joost Oppenheim: A pioneer of cytokine research
Cytokine. 2024 Feb 23:156544. doi: 10.1016/j.cyto.2024.156544. Online ahead of print.NO ABSTRACTPMID:38402113 | DOI:10.1016/j.cyto.2024.156544 (Source: Cytokine)
Source: Cytokine - February 24, 2024 Category: Molecular Biology Authors: Dhan V Kalvakolanu Howard A Young Scott Durum Source Type: research
Joost Oppenheim: A pioneer of cytokine research
Cytokine. 2024 Feb 23:156544. doi: 10.1016/j.cyto.2024.156544. Online ahead of print.NO ABSTRACTPMID:38402113 | DOI:10.1016/j.cyto.2024.156544 (Source: Cytokine)
Source: Cytokine - February 24, 2024 Category: Molecular Biology Authors: Dhan V Kalvakolanu Howard A Young Scott Durum Source Type: research
Causal relationships between circulating inflammatory cytokines and diabetic neuropathy: A Mendelian Randomization study
CONCLUSION: Our MR research identified four upstream inflammatory cytokines implicated in diabetic neuropathy. Overall, these findings suggest the potential for innovative therapeutic strategies. Further large-scale cohort studies are required for validation.PMID:38395012 | DOI:10.1016/j.cyto.2024.156548 (Source: Cytokine)
Source: Cytokine - February 23, 2024 Category: Molecular Biology Authors: Zhaoxiang Wang Li Zhang Bing Lu Heping Sun Shao Zhong Source Type: research
Causal relationships between circulating inflammatory cytokines and diabetic neuropathy: A Mendelian Randomization study
CONCLUSION: Our MR research identified four upstream inflammatory cytokines implicated in diabetic neuropathy. Overall, these findings suggest the potential for innovative therapeutic strategies. Further large-scale cohort studies are required for validation.PMID:38395012 | DOI:10.1016/j.cyto.2024.156548 (Source: Cytokine)
Source: Cytokine - February 23, 2024 Category: Molecular Biology Authors: Zhaoxiang Wang Li Zhang Bing Lu Heping Sun Shao Zhong Source Type: research
Interferon- α induces differentiation of cancer stem cells and immunosuppression in hepatocellular carcinoma by upregulating CXCL8 secretion
In this study, we investigated whether IFN-α could directly induce the production of CXCL8 in HCC cells and whether CXCL8 could antagonize the antitumor activity of IFN-α. We found that IFN-α not only upregulated the expression of the inducible genes CXCL9, CXCL10, CXCL11 and PD-L1, but also significantly stimulated CXCL8 secretion in HCC cells. Mechanically, IFN-α induces CXCL8 expression by activating the AKT and JNK pathways. In addition, our results demonstrate that IFN-α exposure significantly increases the differentiation of HCC stem cells, but this effect is reversed by the addition of the CXCL8 receptor CXCR1/...
Source: Cytokine - February 22, 2024 Category: Molecular Biology Authors: Yu-Ting Ma Lu Zheng Cheng-Wen Zhao Yue Zhang Xin-Wei Xu Xin-Yu Wang Guo-Ping Niu Zhong-Song Man Feng Gu Yong-Qiang Chen Source Type: research
Expression of concern "Expression of fibroblast growth factor 21 in patients with biliary atresia" [Cytokine 83 (2016) 13-18]
Cytokine. 2024 Apr;176:156525. doi: 10.1016/j.cyto.2024.156525. Epub 2024 Feb 3.NO ABSTRACTPMID:38388068 | DOI:10.1016/j.cyto.2024.156525 (Source: Cytokine)
Source: Cytokine - February 22, 2024 Category: Molecular Biology Authors: Dawei Li Tianfei Lu Conghuan Shen Yuan Liu Jiang Zhang Yuhua Shan Yi Luo Zhifeng Xi Bijun Qiu Qimin Chen Jianjun Zhang Qiang Xia Source Type: research
