A case of large cell neuroendocrine carcinoma of the uterine cervix misdiagnosed as adenocarcinoma in Thinprep cytology test
Jong-Hee Nam, Jongin Na, Nah-Ihm Kim, Ga-Eon Kim, Chang-Soo Park, Yoo-Duk ChoiCytoJournal 2017 14(1):28-28 Large cell neuroendocrine carcinoma (LCNEC) of uterine cervix is a rare malignancy with aggressive behavior and poor clinical outcome even in its early stage. Few cytopathologic features of cervical LCNEC have been reported previously. A 57-year-old postmenopausal African American female, presented to the local health department with a chief complaint of heavy vaginal bleeding. A 45-year-old female presented with 20 months of vaginal pruritus and foul odor. Cervical malignancy was suspected by pelvis magnetic resonan...
Source: CytoJournal - November 24, 2017 Category: Pathology Authors: Jong-Hee Nam Jongin Na Nah-Ihm Kim Ga-Eon Kim Chang-Soo Park Yoo-Duk Choi Source Type: research

Cytologic features of primary monophasic synovial sarcoma of the thyroid gland
This report presents fine needle aspiration (FNA) cytology of primary monophasic SS of the thyroid gland. A 47-year- old woman incidentally detected thyroid nodule in the isthmus of right thyroid gland on an ultrasonography by regular health check-up. Because the possibility of malignancy could not be ruled out, FNA and surgical resection were performed. The cytological, histopathological, immunohistochemical, and molecular genetic study of SYT-SSX transcript were discussed. For the past 3 years of follow-up after surgery, no recurrence or metastasis has been identified. (Source: CytoJournal)
Source: CytoJournal - October 12, 2017 Category: Pathology Authors: Chang-Soo Park Young Kim Eun-Hui Jeong Nah-Ihm Kim Yoo-Duk Choi Source Type: research

A case of painful ankle swelling: Cytomorphological clues and pitfalls
Biswajit Dey, Archana Hemant Deshpande, Pushpanjali Ojha, Chitrawati Bal Gargade, Jitendra Singh Nigam, Amit RayCytoJournal 2017 14(1):25-25 (Source: CytoJournal)
Source: CytoJournal - October 12, 2017 Category: Pathology Authors: Biswajit Dey Archana Hemant Deshpande Pushpanjali Ojha Chitrawati Bal Gargade Jitendra Singh Nigam Amit Ray Source Type: research

Cytomorphological spectrum of epididymal nodules: An institution & #39;s experience
Conclusions: FNAB is an easily available technique for palpable lesions of epididymis, and it helps in making an early, near definitive diagnosis of epididymal lesions. It also helps to avoid unnecessary surgical interventions and helps in timely management. (Source: CytoJournal)
Source: CytoJournal - October 12, 2017 Category: Pathology Authors: Jyotsna Naresh Bharti Biswajit Dey Jenna Bhattacharya Shyama Jain Source Type: research

Perihepatic cystic mass: Zebra or horse ?
Alan Marcus, June Koizumi, Brian Robinson, Tamara GiorgadzeCytoJournal 2017 14(1):21-21 (Source: CytoJournal)
Source: CytoJournal - September 25, 2017 Category: Pathology Authors: Alan Marcus June Koizumi Brian Robinson Tamara Giorgadze Source Type: research

Significance of finding benign endometrial cells in women 40 & #8211;45 versus 46 years or older on Papanicolaou tests and histologic follow-up
Conclusion: Clinically significant endometrial lesions occurred predominantly in women older than 50 years (4.6%) and in only one woman between ages 46 and 50 years (1.5%). Therefore, endometrial sampling should be performed in women aged 47 years and older with BECs, especially when additional clinical indicators (e.g., postmenopausal bleeding) are recognized. (Source: CytoJournal)
Source: CytoJournal - September 25, 2017 Category: Pathology Authors: Shanna M Colletti Ghassan A Tranesh Aziza Nassar Source Type: research

Fine needle aspiration of spindle cell ductal carcinoma in situ of the breast: A case report and the use of ancillary tests for the differential diagnosis of metaplastic carcinoma
Yosep Chong, Young Sub Lee, Tae-Jung Kim, Woo-Chan Park, Chang Suk Kang, Eun Jung LeeCytoJournal 2017 14(1):23-23 Spindle cell ductal carcinoma in situ (DCIS) is a recently recognized subtype of DCIS, which is associated with a very rare and unique morphology. Although the histologic features have been relatively well described in a few reports, the cytologic features have not. Even though the distinction of this lesion from usual DCIS is not crucial clinically, it should be noted that this lesion might simulate the features of metaplastic carcinoma on fine needle aspiration cytology. Here, we report a case of spindle cel...
Source: CytoJournal - September 25, 2017 Category: Pathology Authors: Yosep Chong Young Sub Lee Tae-Jung Kim Woo-Chan Park Chang Suk Kang Eun Jung Lee Source Type: research

Cytologic features of tubular adenoma of ampulla causing distal common bile duct stricture: A case report and review of the literature
Sangeeta Mantoo, Madhusudhan R Sanaka, Deborah J ChuteCytoJournal 2017 14(1):19-19 Adenomas of the ampulla of Vater are distinctly rare, representing <10% of periampullary neoplasms. Very few reports of the cytologic features of ampullary adenomas are present in literature, particularly in bile duct brushing samples. A case report and review of the literature is presented. The typical cytologic features of ampullary adenomas on cytologic preparations include tall, thin columnar cells with mildly hyperchromatic elongated nuclei and nuclear pseudostratification, in a relatively clean background. The ke...
Source: CytoJournal - August 22, 2017 Category: Pathology Authors: Sangeeta Mantoo Madhusudhan R Sanaka Deborah J Chute Source Type: research

Can an inadequate cervical cytology sample in ThinPrep be converted to a satisfactory sample by processing it with a SurePath preparation ?
Conclusions: Converting cytology samples from ThinPrep to SurePath processing can reduce the number of unsatisfactory samples. The samples should be run through the “nongynecology” program to ensure an adequate number of cells. (Source: CytoJournal)
Source: CytoJournal - August 22, 2017 Category: Pathology Authors: Sveinung Wergeland Sorbye Mette Kristin Pedersen Bente Ekeberg Merete E. Johansen Williams Torill Sauer Ying Chen Source Type: research

Interobserver reproducibility of the Paris system for reporting urinary cytology
Conclusions: Our findings indicated that the scheme recommended by the Paris System shows adequate precision for the category NHGUC, but the other categories demonstrated unacceptable interobserver variability. This low level of diagnostic precision may negatively impact the applicability of the Paris System for widespread clinical application. (Source: CytoJournal)
Source: CytoJournal - July 24, 2017 Category: Pathology Authors: Theresa Long Lester J Layfield Magda Esebua Shellaine R Frazier D Tamar Giorgadze Robert L Schmidt Source Type: research

A diagnostically difficult case of a cellular pleural fluid: Morphology, immunohistochemistry, and fluorescence in situ hybridization study
Minhua Wang, Shabnam Samankan, Amarpreet Bhalla, N Paul Ohori, Nora K FrischCytoJournal 2017 14(1):18-18 (Source: CytoJournal)
Source: CytoJournal - July 24, 2017 Category: Pathology Authors: Minhua Wang Shabnam Samankan Amarpreet Bhalla N Paul Ohori Nora K Frisch Source Type: research

Myoepithelioma of soft tissue in the gluteal region: Diagnostic pitfall in cytology
Viral M Bhanvadia, Neeru M Agarwal, Alpesh D Chavda, Bharat V BhetariyaCytoJournal 2017 14(1):14-14 (Source: CytoJournal)
Source: CytoJournal - June 20, 2017 Category: Pathology Authors: Viral M Bhanvadia Neeru M Agarwal Alpesh D Chavda Bharat V Bhetariya Source Type: research

Metastatic prostatic stromal sarcoma: A challenging diagnosis on fine-needle aspiration with broad differential diagnosis
We report a 48-year-old man diagnosed with metastatic high grade prostatic stromal sarcoma by a CT-scan guided fine needle aspiration (FNA) biopsy of a right lower lung lobe nodule. We reviewed the literature on the epidemiologic, cyto-histological, and immunophenotypic findings and discussed the differential diagnosis for this rare entity. (Source: CytoJournal)
Source: CytoJournal - June 20, 2017 Category: Pathology Authors: Muhammad Siddique Khurram Ghassan Tranesh Ramen Sakhi Ameer Hamza Warda Ibrar Roohi Bano Source Type: research

Metastatic neoplasms to the thyroid diagnosed by fine-needle aspiration/core needle biopsy: Clinicopathologic and cytomorphologic correlation
Conclusion: Metastases to the thyroid diagnosed by FNA and/or CNB are exceedingly rare in our institution, comprising only 0.04% of total FNA/CNB and only 1.1% of all thyroid neoplasms. We report the first known case of metastatic olfactory neuroblastoma to the thyroid diagnosed by aspiration cytology. In addition, an occult primary may present as a thyroid mass on FNA or CNB as occurred with two of our cases. FNA/CNB proved to be highly effective in the diagnosis of metastases to the thyroid, with ROSE proving valuable in assuring specimen adequacy. Thyroid FNA and CNB demonstrated great utility in t...
Source: CytoJournal - June 20, 2017 Category: Pathology Authors: Mobeen Rahman Ashley Rae Okada Kevin Guan Pamela Tauchi-Nishi Source Type: research

An elderly man with a solitary liver lesion
Lisa Barton, Lichao Zhao, Jessica N Doty, Thomas Stasko, Rachel ConradCytoJournal 2017 14(1):11-11 (Source: CytoJournal)
Source: CytoJournal - May 26, 2017 Category: Pathology Authors: Lisa Barton Lichao Zhao Jessica N Doty Thomas Stasko Rachel Conrad Source Type: research