Cystatin C and Seminal Parameter Evaluation in Patients with End-Stage Renal Disease
Objective:We aimed to investigate the possible relationship between seminal parameters and cystatin C seminal levels in an infertility evaluation of chronic hemodialysis patients.Materials and Methods:This was a cross-sectional study, aged 18-60 years, in a group of 60 men undergoing hemodialysis (case) for more than 6 months, and a group of 15 healthy men (control) without clinical or laboratory signs of genitourinary tract infection. We performed a spermogram, hormonal profile, and assessment of leukocytes and cystatin levels in the semen.Results: The ages in the case and control were similar (p = 0.060).The seminal cyst...
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Acknowledgements to Reviewers
Curr Urol 2020;14:222-224 (Source: Current Urology)
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Squamous Cell Carcinoma in a Transgender Man's Neo-Urethra after Metoidioplasty
We report the novel case of a patient with urethral stricture 4 years after metoidioplasty found to have squamous cell carcinoma in situ likely originating from the vaginal mucosa grafted to the neourethra, and highlight the importance of sending such strictures for pathologic evaluation.Curr Urol 2020;14:219-221 (Source: Current Urology)
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Should Scrotal Color Doppler Ultrasound Be Routinely Indicated in Fertility Evaluation of Non-Azoospermic Men?
Conclusions:Testicular volume which has a close relation to the semen parameters could be used as a clinical prediction factor for the quality of semen.Curr Urol 2020;14:211-218 (Source: Current Urology)
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Investigation of Triamcinolone Instillation in the Long-term Rate of Anterior Urethral Strictures' Recurrence
In this study, the efficacy of triamcinolone instillation based on a newly introduced protocol on the rate of recurrence in patients with anterior urethral strictures was evaluated.Methods:A total of 66 patients were divided into treatment group (n = 33), in which triamcinolone was instilled on urethra after removing of Foley catheter and control group (n = 33) that not received any intervention. Each 40 mg/1 ml of triamcinolone vial was dissolved in 9 ml of distilled water and then a 2 ml of diluted solution was used for each instillation and 8 ml was kept in 4 °C. Triamcinolone was instilled based on daily in week 1, ev...
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Antimicrobial Susceptibility Patterns of < b > < i > Escherichia coli < /i > < /b > among Tunisian Outpatients with Community-Acquired Urinary Tract Infection (2012-2018)
Conclusion:Antimicrobial susceptibility profiles of uropathogenicE. coli are constantly changing, due to modifications in the antibiogram interpretation criteria and antibiotic prescription habits. Rigorous surveillance of resistance rate is necessary to determine appropriate empirical treatment and limit the spread of multiresistant strains.Curr Urol 2020;14:200-205 (Source: Current Urology)
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Evaluation of Holmium Laser Enucleation of the Prostate Learning Curves with and without a Structured Training Programme
Background/Aims:To evaluate perioperative parameters, early functional outcomes, and the safety profile of holmium laser enucleation of the prostate learning curves with and without mentoring.Methods:The learning curves of 2 surgeons of their first 100 consecutive patients treated with holmium laser enucleation of the prostate were retrospectively analyzed. We analyzed demographic parameters, clinical outcomes, adverse events, and the progress during each learning experience.Results: The only statistically significant differences between the two learning curves were found for operation time (138.2 ± 60.7 vs. 98.2 ± 37.7 ...
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Tumor Location Based Segmentation in Upper-Tract Urothelial Carcinoma Impacts on the Urothelial Recurrence-Free Survival: A Multi-Institutional Database Study
Introduction and Objectives:The predictive impact of primary tumor location for patients with upper-tract urothelial carcinoma (UTUC) in the presence of concomitant urothelial bladder cancer, along with urothelial recurrence after the curative treatment is still contentious. We evaluated the association between precise tumor location and concomitant presence of urothelial bladder cancer and urothelial recurrence-free survival in patients with UTUC treated by radical nephroureterectomy with a bladder cuff.Methods:A total of 1,349 patients with localized UTUC (Ta-4N0M0) from a retrospective multi-institutional cohort were st...
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Cognitive and Psychological Impacts of Different Treatment Options for Prostate Cancer: A Critical Analysis
Conclusion:Emotional distress and cognitive decline may accompany every PCa treatment option to different degrees. Accurate information on the short- and long-term effect of treatments on cognitive and psychological aspects should be provided to patients during treatment decision-making. There is also a need to develop well-targeted psychological and neurological interventions that could help those experiencing ongoing post-treatment difficulties.Curr Urol 2020;14:169-177 (Source: Current Urology)
Source: Current Urology - December 17, 2020 Category: Urology & Nephrology Source Type: research

Adrenal-Renal Fusion with Adrenal Cortical Adenoma and Ectopic Adrenal Tissue, Presenting as Suspected Renal Mass: A Case Report
We describe a case of a 62-year-old woman with an upper pole cystic renal mass on imaging, who underwent robotic partial nephrectomy. Intraoperatively the renal mass was found to be an adrenal-renal fusion anomaly, with ectopic adrenal tissue. Adrenal-renal infusion of an adrenal cortical adenoma was confirmed on final pathology. Due to lack of imaging-based diagnosis, this condition should be considered in the differential for upper pole renal masses.Curr Urol 2020;14:163-165 (Source: Current Urology)
Source: Current Urology - October 12, 2020 Category: Urology & Nephrology Source Type: research

Cook's Hernia: Renal Tumor Parasitic Vessels Herniating into Right Inguinal Canal
We report the incidental findings and management of a hernia whose contents included renal tumor parasitic vessels in a 52-year-old male who presented with a 22 cm large right renal tumor. His initial complaints were right sided fullness and hematuria. Incidentally on CT scan, the patient's large right renal mass was identified, as well as lower pole parasitic tumor vessels which were herniating into the patient's right inguinal canal. Parasitic tumor vessels are often found on larger obscure tumors. Few side effects or associated problems have been reported from issues with the parasitic vessels other than excessive bleed...
Source: Current Urology - October 12, 2020 Category: Urology & Nephrology Source Type: research

The Effect of Acetylcysteine on Renal Function in Experimental Models of Cyclophosphamide-and Ifosfamide-Induced Cystitis
Conclusions: Acetylcysteine used in the experimental model of cyclophosphamide- and ifosfamide-induced cystitis had a uroprotective effect and also reduced renal dysfunction, which suggests its potential use as a nephroprotective compound in cyclophosphamide/ifosfamide therapy.Curr Urol 2020;14:150-162 (Source: Current Urology)
Source: Current Urology - October 12, 2020 Category: Urology & Nephrology Source Type: research

Prostate-Specific Antigen Modulatory Effect of a Fermented Soy Supplement for Patients with an Elevated Risk of Prostate Cancer: a Non-Randomized, Retrospective Observational Registration
Objective: To investigate the efficacy of a 6-month fermented soy supplement (equol-containing), measured by prostate-specific antigen (PSA) stabilization or PSA decrease from baseline (PSA modulatory effect) in men with an elevated risk of prostate cancer (PCa), with a WHO performance 0-2 and a follow-up of 12 months.Methods: The patient population consisted of men with an elevated risk of PCa and a prior negative prostate biopsy within 1 year from starting therapy. Serum PSA values were recorded at inclusion (iPSA), at 6 months (1PSA), and optionally at 12 months (2PSA). Statistical analysis was carried out using the Wil...
Source: Current Urology - October 12, 2020 Category: Urology & Nephrology Source Type: research

Preoperative Clinical Predictors of Lymphovascular Invasion of Bladder Tumors at Transurethral Resection Pathology
Background: The assessment of lymphovascular invasion (LVI) on the specimens of a transurethral resection of bladder tumors (TURBT) is very important for risk stratification and decision-making on further treatment for bladder cancer.Objectives: The present study aimed to identify clinical predictors associated with the risk of bladder cancer with LVI before a first TURBT.Methods: A total of 291 patients underwent a first TURBT for bladder cancer at Toho University Sakura Medical Center between January 2012 and December 2016. We analyzed predictors of LVI based on data from 217 patients and predictors of high grade and ≥...
Source: Current Urology - October 12, 2020 Category: Urology & Nephrology Source Type: research

A Retrospective Study of Immunotherapy Treatment with Uro-Vaxom (OM-89 ®) for Prophylaxis of Recurrent Urinary Tract Infections
Objectives: To present our experience with the long-term preventive effect of immunotherapy with Uro-Vaxom ® on recurrent urinary tract infections (UTI) in adult patients.Materials and Methods: Retrospective analysis of 79 patients with recurrent UTI treated with Uro-Vaxom. Recurrent UTIs were defined as ≥ 2 infections in 6 months or ≥ 3 in 12 months. Patients received a 6 mg Uro-Vaxom capsule daily for 90 days followed by discontinuation for 3 months and then administration for the first 10 days of subsequent months 7, 8 and 9 as a ‘booster' regime. The primary outcome measure was the number of UTIs encountered in ...
Source: Current Urology - October 12, 2020 Category: Urology & Nephrology Source Type: research