Association of Kidney Stones and Recurrent UTIs: the Chicken and Egg Situation. A Systematic Review of Literature
AbstractPurpose of ReviewKidney stone disease (KSD) and recurrent urinary tract infections (rUTI) are frequently concomitant conditions. We conducted a systematic review to determine the association of UTI in patients with KSD and to assess the outcomes of kidney stone treatment in the resolution of rUTI.Recent FindingsOur systematic review included 17 papers and a strong association between KSD and rUTI was demonstrated by numerous studies. Surgical clearance of kidney stones usually resulted in the resolution of UTI, but discordant data persist regarding recurrence rates after surgery. In vitro studies might unveil the c...
Source: Current Urology Reports - July 25, 2022 Category: Urology & Nephrology Source Type: research
Correction to: Role of Probiotics for Recurrent UTIs in the Twenty-First Century: a Systematic Review of Literature
(Source: Current Urology Reports)
Source: Current Urology Reports - July 13, 2022 Category: Urology & Nephrology Source Type: research
Role of Hysteropexy in the Management of Pelvic Organ Prolapse
AbstractPurpose of ReviewTo discuss considerations for hysteropexy for apical pelvic organ prolapse (POP) and summarize available literature comparing various hysteropexy techniques to analogous procedures involving hysterectomy.Recent FindingsHysteropexy for apical POP has increased in popularity in recent years, although anatomic factors and gynecologic cancer risk must be taken into account. Native tissue hysteropexy options include the LeFort colpocleisis, sacrospinous hysteropexy, and uterosacral hysteropexy. Although vaginal mesh was banned by the Food and Drug Administration in 2019, abdominal mesh sacrohysteropexy ...
Source: Current Urology Reports - July 5, 2022 Category: Urology & Nephrology Source Type: research
Update on Urethral Bulking for Stress Urinary Incontinence in Women
AbstractPurpose of ReviewUrethral bulking agents are an effective treatment for stress urinary incontinence in select females. The material and techniques used for urethral bulking are constantly evolving. With the introduction of several new agents, there is an ongoing debate over which agent is the most effective, durable, and safe.Recent FindingsCurrent available bulking agents include Bulkamid ®, Macroplastiue®, Durasphere®, Coaptite®, or Urolastic®. Each of these agents has its own biophysical properties that affect its efficacy and safety. Evidence evaluating bulking agents has increased over time but there is n...
Source: Current Urology Reports - July 4, 2022 Category: Urology & Nephrology Source Type: research
Review of Ischemic and Non-ischemic Priapism
AbstractPurpose of ReviewPriapism is a rare condition that has different presentations, etiologies, pathophysiology, and treatment algorithms. It can be associated with significant patient distress and sexual dysfunction. We aim to examine the most up-to-date literature and guidelines in the management of this condition.Recent FindingsPriapism is a challenging condition to manage for urologists, since the etiology is often multi-factorial and the suggested treatment algorithms are based on small studies and expert anecdotal experience, perhaps due to the rarity of the disorder.SummaryIschemic priapism of less than 24 h c...
Source: Current Urology Reports - July 1, 2022 Category: Urology & Nephrology Source Type: research
The Use of Neutrophil Gelatinase –Associated Lipocalin (NGAL) as a Diagnostic and Prognostic Biomarker in Urinary Tract Obstruction: a Systematic Review
AbstractPurpose of ReviewThe early recognition of urinary tract obstruction (UTO) is vital in order to prevent mortality and morbidity associated with an acute kidney injury (AKI) and progression to irreversible kidney damage. Urinary biomarkers such as neutrophil gelatinase –associated lipocalin(NGAL) have been recognised as an accurate tool in the timely diagnosis of AKI, but its role in the detection, prognosis and subsequent monitoring of a variety of obstructive uropathies has not yet been explored. We performed a systematic review of literature in accordance with Cochrane methodology from inception to August 2021.R...
Source: Current Urology Reports - June 9, 2022 Category: Urology & Nephrology Source Type: research
Combination and Novel Pharmacologic Agents for OAB
AbstractPurpose of ReviewTo evaluate recent literature on combination and novel pharmacologic therapies for overactive bladder (OAB).Recent FindingsCombination therapies demonstrating greater efficacy than monotherapy include combination anticholinergics, anticholinergic plus β-3 agonist, and anticholinergic with behavioral modification, percutaneous tibial nerve stimulation, or sacral neuromodulation. Promising novel therapies include new bladder selective anticholinergics, new β-3 agonists, and gabapentin.SummaryOAB is a symptom complex caused by dysfunction in the interconnected neural, muscular, and urothelial system...
Source: Current Urology Reports - May 14, 2022 Category: Urology & Nephrology Source Type: research
Review of Ischemic and Non-ischemic Priapism
AbstractPurpose of ReviewPriapism is a rare condition that has different presentations, etiologies, pathophysiology, and treatment algorithms. It can be associated with significant patient distress and sexual dysfunction. We aim to examine the most up-to-date literature and guidelines in the management of this condition.Recent FindingsPriapism is a challenging condition to manage for urologists, since the etiology is often multi-factorial and the suggested treatment algorithms are based on small studies and expert anecdotal experience, perhaps due to the rarity of the disorder.SummaryIschemic priapism of less than 24 h c...
Source: Current Urology Reports - May 10, 2022 Category: Urology & Nephrology Source Type: research
Diagnosis and Treatment of Small Renal Masses: Where Do We Stand?
AbstractPurpose of ReviewTo present an overview of the current evidence-based studies covering diagnostic and management of SRM.Recent FindingsRenal cell carcinoma (RCC) represents 3% of the cancers. Nowadays, partial nephrectomy (PN) represents gold standard treatment. New nephron-sparing approaches such as active surveillance and ablative therapies have been increasingly used as an alternative to surgical intervention. Due to novel comprehension of RCC and widespread use of imaging techniques, diagnosis at early stage in elderly patients has increased. Treatment decision-making should be based on patient and tumour chara...
Source: Current Urology Reports - May 4, 2022 Category: Urology & Nephrology Source Type: research
Non-antibiotic Approaches to Preventing Pediatric UTIs: a Role for D-Mannose, Cranberry, and Probiotics?
AbstractPurpose of ReviewWhile antibiotics have been a staple in the management and even prevention of urinary tract infections (UTIs), it is not without significant consequences due to intolerance and development of antibiotic resistant bacteria. These concerns necessitate alternatives to antibiotic use in the management of pediatric UTIs. This review seeks to evaluate non-antibiotic means of preventing UTI in the pediatric population.Recent FindingsThe search for preventative alternatives to antibiotics has included D-mannose, cranberry, and probiotics. These products similarly work through competitive inhibition of urop...
Source: Current Urology Reports - April 20, 2022 Category: Urology & Nephrology Source Type: research
Clear Cell Renal Cell Carcinomas with Aggressive Behavior Display Low Intratumor Heterogeneity at the Histological Level
AbstractPurpose of ReviewIntratumor heterogeneity (ITH) is an inherent characteristic of most tumors and its detection remains a key task for pathologists. However, the clinical significance of the degree of development of this feature is still poorly understood.Recent FindingsA series of 28 clear cell renal cell carcinomas (CCRCC) have been exhaustively analyzed with two different sampling protocols [multisite tumor sampling (MSTS) and total sampling] to evaluate to what point the level (low vs. high) of histological ITH detected in routine practice influences tumor behavior and patients ’ survival. All CCRCC (n = 1...
Source: Current Urology Reports - April 13, 2022 Category: Urology & Nephrology Source Type: research
Intravascular Ultrasound for the Evaluation and Management of Retroperitoneal, Genitourinary Malignancies
AbstractPurpose of ReviewHerein we provide a review of intravascular ultrasound (IVUS) and its ability to assist in the evaluation and surgical management of advanced retroperitoneal, genitourinary tumors.Recent FindingsAdvanced retroperitoneal tumors such as advanced renal cell carcinoma, bulky retroperitoneal lymphadenopathy associated with advanced testicular carcinoma, large adrenal tumors, and retroperitoneal sarcomas can invade, compress, or distort vascular anatomy making surgical resection challenging and high risk. Intravascular ultrasonography is commonly used by vascular and cardiothoracic surgery to provide a r...
Source: Current Urology Reports - March 14, 2022 Category: Urology & Nephrology Source Type: research
Surgical Complications in the Management of Benign Prostatic Hyperplasia Treatment
AbstractPurpose of ReviewThere are a variety of treatment options for men with symptomatic benign prostatic hyperplasia (BPH); transurethral resection of the prostate (TURP) remains the gold standard surgical treatment. The field continues to evolve with the introduction of new energy and laser technologies, increasing adoption of enucleation techniques, in addition to the advent of minimally invasive surgical technologies (MIST) that enable office-based treatments. The choice in surgical management has become very nuanced depending on a variety of patient and anatomic factors. There continues to be high success rates for ...
Source: Current Urology Reports - March 9, 2022 Category: Urology & Nephrology Source Type: research
