Epidemiology, Clinical, and Therapeutic Aspects of Paracoccidioidomycosis
Abstract Paracoccidioidomycosis, or PCM, was described by Adolfo Lutz 105 years ago. Since then the disease has taken a prominent position among the systemic fungal infections because it mainly affects individuals in the most productive years of their lives in various countries of Latin America. In Brazil, the disease is considered endemic in some regions. However, it is still a neglected disease. With the recent discovery that Paracoccidioides brasiliensis is not the only species of this genus, numerous studies have contributed to better understanding and recognition of this pathogen and its pathology in ma...
Source: Current Tropical Medicine Reports - June 1, 2014 Category: Tropical Medicine Source Type: research

Shigella: A Highly Virulent and Elusive Pathogen
Abstract Despite a significant decrease in Shigella-related mortality, shigellosis continues to carry a significant burden of disease worldwide, particularly in Asia and Africa. Shigella is a highly virulent pathogen comprised of four major species with numerous subtypes. Shigella dysenteriae and Shigella flexneri infections are predominant in resource-limited settings. Clinical presentations range from mild watery diarrhea to severe dysentery with systemic complications such as electrolyte imbalance, seizures and hemolytic uremic syndrome. S. dysenteriae subtype 1, the producer of Shiga toxin, causes the most se...
Source: Current Tropical Medicine Reports - June 1, 2014 Category: Tropical Medicine Source Type: research

Tropical Medicine in the Horse Latitudes
Abstract Some of the world’s highest rates of neglected tropical diseases (NTDs) now occur among impoverished populations who live in the midst of wealth, especially in middle- and high-income countries. An illustrative example is the poor who live in nations between the 30th and 35th parallels, also known as the “horse latitudes.” Focusing on the northern horse latitudes, emerging information reveals that the neglected tropical diseases are widespread in the Middle East and North Africa, Afghanistan, Pakistan, North India, Nepal, China, and in Texas and the southern United States, particularly ...
Source: Current Tropical Medicine Reports - March 1, 2014 Category: Tropical Medicine Source Type: research

The History of Dengue in the United States and its Recent Emergence
Abstract Dengue virus (DENV) is the most common and widespread vector-borne arbovirus in the world, and over the past 30 years, there has been a dramatic increase in incidence and geographic spread. Considering the difficulty of preventing infections and consequence of severe disease, it is important to reflect on the history of dengue in the United States and focus attention on its recent re-emergence. In this paper, we report the historical significance of dengue outbreaks in the USA between 1780 and 1945, along with the elimination strategies of the vector mosquito, Aedes aegypti. We then detail the re-em...
Source: Current Tropical Medicine Reports - March 1, 2014 Category: Tropical Medicine Source Type: research

Current Tropical Medicine Reports: A Path Forward to Highlight Research and Clinical Advances, New Trends and Innovations
(Source: Current Tropical Medicine Reports)
Source: Current Tropical Medicine Reports - March 1, 2014 Category: Tropical Medicine Source Type: research