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Regulation of ROS/inflammasome Axis is Essential for Cardiac Regeneration in Aging Rats Receiving Transplantation of Mesenchymal Stem Cells
CONCLUSION: These findings suggest that mesenchymal stem cell transplantation effectively ameliorates aging hearts through oxidative stress/inflammasome axis regulation. The results from this study provide clinical potential for stem cell-based therapy in the treatment of aging hearts.PMID:38031779 | DOI:10.2174/011574888X276612231121065203 (Source: Current Stem Cell Research and Therapy)
Source: Current Stem Cell Research and Therapy - November 30, 2023 Category: Stem Cells Authors: Wei-Syun Hu Jing-Yi Chen Wei-Yu Liao Chin-Hsien Chang Tung-Sheng Chen Source Type: research

Identifying Dental Pulp Stem Cell as A Novel Therapeutic Strategy for Digestive Diseases
Curr Stem Cell Res Ther. 2023 Nov 24. doi: 10.2174/011574888X275737231120045815. Online ahead of print.ABSTRACTMesenchymal stem cells (MSCs) have been identified as potential therapeutics for various diseases. In contrast to other sources of MSCs, dental stem cells (DSCs) have received increased attention due to their high activity and easy accessibility. Among them, dental pulp stem cells (DPSCs) exhibit superior self-renewal, multipotency, immunomodulatory, and regenerative capacities. Following their inspiring performance in animal models and clinical trials, DPSCs show pharmacological potential in regenerative medicine...
Source: Current Stem Cell Research and Therapy - November 29, 2023 Category: Stem Cells Authors: Xieyin Sun Zhaoyi Lin Nuo Xu Yinqi Chen Saiyan Bian Wenjie Zheng Source Type: research

The miR-210 Primed Endothelial Progenitor Cell Exosomes Alleviate Acute Ischemic Brain Injury
CONCLUSION: These findings suggest that miR210-EPC-EXs protect the brain from acute ischemia- induced cell apoptosis and oxidative stress partially through the VEGFR2/PI3k and TrkB/PI3k signal pathways.PMID:37957914 | DOI:10.2174/011574888X266357230923113642 (Source: Current Stem Cell Research and Therapy)
Source: Current Stem Cell Research and Therapy - November 14, 2023 Category: Stem Cells Authors: Jinju Wang Shuzhen Chen Harshal Sawant Yanfang Chen Ji Bihl Source Type: research

Differentiation of Human Adipose-derived Stem Cells to Exosome-affected Neural-like Cells Extracted from Human Cerebrospinal Fluid Using Bioprinting Process
CONCLUSION: CSF-derived exosomes can contribute to the neuronal differentiation of adipose- derived stem cells in alginate hydrogel scaffolds created by the bioprinting process.PMID:37957915 | DOI:10.2174/011574888X270145231102062259 (Source: Current Stem Cell Research and Therapy)
Source: Current Stem Cell Research and Therapy - November 14, 2023 Category: Stem Cells Authors: Mojtaba Cheravi Javad Baharara Parichehreh Yaghmaei Nasim Hayati Roudbari Source Type: research